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Clinical trials for Osteoarthritis, Knee AND Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    228 result(s) found for: Osteoarthritis, Knee AND Pain. Displaying page 4 of 12.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2008-001712-21 Sponsor Protocol Number: ESBA105CRD02 Start Date*: 2009-03-05
    Sponsor Name:Delenex Therapeutics AG
    Full Title: A double-blind, randomised placebo-controlled Phase I/IIa study to investigate the safety, tolerability and efficacy on pain of intra-articular ESBA105 applied to patients with severely painful os...
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-002598-13 Sponsor Protocol Number: 42160443PAI3003 Start Date*: 2015-06-24
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: Randomized, 16-Week, Multi-Phase, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Fulranumab as Monotherapy in Subjects with Signs and Symptoms of Osteo...
    Medical condition: Osteoarthritis of the Hip or Knee
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004859 10023476 Knee osteoarthritis LLT
    17.1 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) BE (Completed) CZ (Prematurely Ended) GB (Completed) NL (Completed) PL (Completed) FR (Completed) SK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003879-37 Sponsor Protocol Number: 42160443PAI3002 Start Date*: 2015-07-17
    Sponsor Name:Janssen-Cilag International NV
    Full Title: Randomized, 16-Week, Multi-Phase, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Fulranumab as Monotherapy in Subjects with Signs and Symptoms of Osteo...
    Medical condition: Osteoarthritis of the Hip or Knee
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10023476 Knee osteoarthritis LLT
    18.1 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-002439-10 Sponsor Protocol Number: PAKA-33601-AS117013 Start Date*: 2013-10-23
    Sponsor Name:University of Warwick [...]
    1. University of Warwick
    2. University Hospitals Coventry & Warwickshire NHS Trust
    Full Title: Perioperative Analgesia for Knee Arthroplasty: A prospective randomised controlled trial
    Medical condition: Osteoarthritis of the knee is a common problem; it causes inability to walk without pain and a reduction in activity levels. Total knee replacements are performed for relief of this disabilitating ...
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-003602-26 Sponsor Protocol Number: CBA106191 Start Date*: 2007-05-04
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A double-blind, two-period, placebo controlled cross-over study of the effects of the CB2 agonist GW842166 on pain and sensitisation in patients with osteoarthritis.
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-004313-41 Sponsor Protocol Number: 47659 Start Date*: 2014-05-19
    Sponsor Name:UMCG
    Full Title: Effect of pre-operative pain treatment by means of duloxetine on postoperative outcome after total hip or knee arthroplasty
    Medical condition: Osteoarthritis (knee or hip)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10023476 Knee osteoarthritis LLT
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014734-16 Sponsor Protocol Number: B0541004 Start Date*: 2010-01-04
    Sponsor Name:Pfizer Limited, Ramsgate Road, Sandwich, Kent CT13 9NJ
    Full Title: A PHASE 2A RANDOMIZED, DOUBLE-BLINDED, DOUBLE DUMMY, PLACEBO AND ACTIVE CONTROLLED, TWO-WAY CROSS-OVER, FLARE-ENRICHED MULTI-CENTRE CLINICAL TRIAL TO EXAMINE THE PAIN RELIEF PRODUCED BY 2 WEEKS OF ...
    Medical condition: OSTEOARTHRITIS OF THE KNEE
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002638-19 Sponsor Protocol Number: 2012GR03 Start Date*: 2013-10-21
    Sponsor Name:University of Dundee & NHS Tayside
    Full Title: The Effect of Spironolactone on Pain in Older People with Osteoarthris
    Medical condition: Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-003224-40 Sponsor Protocol Number: 42160443PAI3007 Start Date*: 2015-11-11
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: Randomized, 16-Week, Multi-Phase, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of Fulranumab as Adjunctive Therapy in Subjects with Signs and Symptoms o...
    Medical condition: Osteoarthritis of the Hip or Knee
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10023476 Knee osteoarthritis LLT
    18.1 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) CZ (Prematurely Ended) HU (Completed) SE (Completed) PL (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-000796-16 Sponsor Protocol Number: 000014/BT Start Date*: 2020-03-03
    Sponsor Name:Bone Therapeutics SA
    Full Title: A Multicenter, Randomized, Double-blind, Placebo- and Active-Controlled Phase III Study on the Safety and Efficacy of a Single Intra-articular Administration of JTA-004 in Symptomatic Knee Osteoart...
    Medical condition: Symptomatic osteoarthritis of the knee with Kellgren-Lawrence grade II and III
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) BE (Completed) GB (GB - no longer in EU/EEA) PL (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2007-001457-26 Sponsor Protocol Number: A6171016 Start Date*: 2008-04-24
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: A LONG-TERM, RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP, PLACEBO-CONTROLLED, RADIOGRAPHIC STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF ORALLY ADMINISTERED SD-6010 IN SUBJECTS WITH SYMPTOMATIC OSTE...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: HU (Completed) BE (Completed) DE (Completed) ES (Completed) CZ (Completed) SK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-002357-23 Sponsor Protocol Number: BUP9007 Start Date*: 2009-03-12
    Sponsor Name:Newcastle Upon Tyne NHS Foundation Trust
    Full Title: An open label, randomized 2 part crossover study to investigate the effect of buprenorphine transdermal delivery system (BTDS) compared with co-codamol on physical activity in subjects aged 60 year...
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-002035-15 Sponsor Protocol Number: 0 Start Date*: 2016-05-20
    Sponsor Name:Helsinki University Central Hospital
    Full Title: Outcome after total knee arthroplasty under general or spinal anesthesia, a randomized study
    Medical condition: Patients undego total knee arthroplasty operation in general or spinal anaesthesia because of osteoarthritis, rheumatoid arthritis or other degenerative condition of the knee
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10031174 Osteoarthrosis LLT
    19.0 100000004859 10031158 Osteo arthritis knees LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-006104-17 Sponsor Protocol Number: CDFV890B12201 Start Date*: 2021-07-21
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, two-arm, placebo-controlled, participant and investigator-blinded study investigating the efficacy, safety and tolerability of DFV890 in patients with symptomatic knee osteoarthritis
    Medical condition: knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Trial now transitioned) SK (Completed) CZ (Trial now transitioned) ES (Ongoing) BE (Completed) RO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-003770-11 Sponsor Protocol Number: GROSKNEEPA01 Start Date*: 2012-11-26
    Sponsor Name:C4Pain ApS
    Full Title: A multi-center, randomized parallel group pilot study to investigate the mechanism of action of tapentadol PR and oxycodone CR in subjects with osteoarthritis knee pain
    Medical condition: Osteoarthritic Knee Pain.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10029877 OA knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-004179-35 Sponsor Protocol Number: OSKNEEPA02 Start Date*: 2012-04-30
    Sponsor Name:C4Pain ApS
    Full Title: A single center, randomized, double-blind, placebo-controlled 2-way crossover study to investigate the mechanism of action of etoricoxib in subjects with osteoarthritis knee pain
    Medical condition: Osteoarthritic Knee Pain.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10029877 OA knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003467-60 Sponsor Protocol Number: M13-741 Start Date*: 2014-06-11
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 2a Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients with Knee Osteoarthritis
    Medical condition: Adult male and female patients with mild to moderate, symptomatic, radiographic and inflammatory osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) GB (Completed) NL (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-002675-97 Sponsor Protocol Number: ONO-4474-02 Start Date*: 2016-12-23
    Sponsor Name:Ono Pharmaceutical Co., Ltd.
    Full Title: A randomised, double-blind, placebo controlled, parallel group, multi-centre, study to evaluate the efficacy, safety, tolerability and pharmacokinetics of ONO-4474 in patients with pain due to oste...
    Medical condition: Osteoarthritic Pain
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10073925 Generalised osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DK (Prematurely Ended) ES (Completed) PL (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-002279-27 Sponsor Protocol Number: DICL001 Start Date*: 2014-10-28
    Sponsor Name:Hi-Tech Pharmacal Co., Inc.
    Full Title: A Double-Blind, Randomized, Placebo-Controlled, Parallel Group, Three-Arm, Multi-Site Study to Evaluate the Clinical Equivalence of Diclofenac Sodium Topical Gel 1% (Hi-Tech Pharmacal Co., Inc.) wi...
    Medical condition: osteoarthritis of the knee
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: EE (Completed) LV (Completed) LT (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001443-39 Sponsor Protocol Number: 167700-004CL Start Date*: 2016-09-23
    Sponsor Name:Proximagen Ltd.
    Full Title: A Randomised, Parallel Arm, Placebo-Controlled, Double-Blind, Study of the Safety and Efficacy of PRX167700 Added to Existing Non-steroidal Anti-inflammatory Therapy in Adults with Moderate-to-Seve...
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) CZ (Completed) PL (Completed) ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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