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Clinical trials for Physiological effect

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    409 result(s) found for: Physiological effect. Displaying page 4 of 21.
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    EudraCT Number: 2012-000122-21 Sponsor Protocol Number: SJ-193 Start Date*: 2012-08-10
    Sponsor Name:Department of Neurology, Roskilde Hospital
    Full Title: Acethylcholineesterase inhibition and orthostatic hypotension in patients with parkinsons disease
    Medical condition: Ortostatic hypotension in patients with Parkinsons disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10031127 Orthostatic hypotension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-001529-27 Sponsor Protocol Number: 20050401 Start Date*: 2005-06-13
    Sponsor Name:Jan Engvall
    Full Title: Effect of reperfusion on infarct size and cardiac function evaluated with MRI and echocardiography/Effekt av reperfusion på infarktstorlek och hjärtfunktion utvärderat med MR och ultraljud
    Medical condition: Patients recovering 6weeks after primary PCI for ST-elevation Myocardial Infarction. This application concerns the use of gadolinium contrast to visualise myocardial infarct size using MRI. Aden...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-005758-39 Sponsor Protocol Number: 9812/A Start Date*: 2006-08-16
    Sponsor Name:Greater Glasgow Health Board
    Full Title: Effect site controlled, reaction time safeguarded, patient maintained sedation with Propofol A) in oral surgery patients B) in general dentistry patients C) in colonoscopy patients
    Medical condition: No specific medical condition. IMP will be used to provide conscious sedation for patients undergoing potentially unpleasant procedures including dentistry and colonoscopy.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-004082-33 Sponsor Protocol Number: erythstom2 Start Date*: 2011-10-05
    Sponsor Name:UZLeuven
    Full Title: The role of induced phase 3 contractions in the control of hunger and food intake
    Medical condition: Gastrointestinal contractility will be studied in healthy volunteers for 7 hours in a fasting condition
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002017-28 Sponsor Protocol Number: LinaclotideRectumColon Start Date*: 2014-07-16
    Sponsor Name:KULEUVEN
    Full Title: ROLE OF THE TYPE AND SITE OF DISTENSION IN THE EVALUATION OF DRUGS EFFICACY IN MODULATING THE SENSORY AND MOTOR RESPONSE OF THE DESCENDING COLON AND THE RECTUM IN MAN
    Medical condition: HEALTHY SUBJECTS AND PATIENTS WITH IRRITABLE BOWEL SYNDROME
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000434-21 Sponsor Protocol Number: LP1 Start Date*: 2005-06-15
    Sponsor Name:Kognitive Neurologie, Institut für Medizin, Forschungszentrum Jülich
    Full Title: Neurochemische Modulation von Exekutiv- und Gedächtnisfunktionen
    Medical condition: Progressive cognitive decline in physiological aging
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004708-51 Sponsor Protocol Number: ABR55478 Start Date*: 2015-12-17
    Sponsor Name:LUMC, VRSP
    Full Title: Facilitating Sexual Memory consolidation by a partial NMDA receptors agonist
    Medical condition: Sexual arousal disorders
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003514-39 Sponsor Protocol Number: GNCbumet Start Date*: Information not available in EudraCT
    Sponsor Name:Gillberg Neuropsychiatry Centre
    Full Title: Testing E/I imbalance in autism with Bumetanide – a parallel group randomized waitlist-control trial in adolescents and adults
    Medical condition: Autism Spectrum Disorder
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000324-19 Sponsor Protocol Number: DDDCF14 Start Date*: 2014-09-18
    Sponsor Name:KU Leuven - Drug Delivery & Disposition
    Full Title: Collection and characterization of gastrointestinal fluids in different populations and conditions
    Medical condition: healthy human volunteers (administration of a proton-pump inhibitor)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2004-003833-15 Sponsor Protocol Number: MEU04/118A Start Date*: 2006-11-21
    Sponsor Name:South Manchester University NHS Trust [...]
    1. South Manchester University NHS Trust
    2. Medicines Evaluation Unit
    3. University of Manchester
    Full Title: A randomised parallel group study to investigate the effect of Seretide withdrawal in COPD using non-invasive biomarkers and physiological measurements
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-003631-37 Sponsor Protocol Number: UDC1 Start Date*: 2017-01-24
    Sponsor Name:Universitaire ziekenhuis Leuven
    Full Title: Therapeutic effect of ursodeoxycholic acid on duodenal permeability and meal related sensory motor function in functional dyspepsia patients
    Medical condition: Functional dyspepsia (FD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-003104-20 Sponsor Protocol Number: Rimona2011 Start Date*: 2011-10-06
    Sponsor Name:UZLeuven
    Full Title: The effect of Acomplia® (rimonabant) on esophageal sensitivity and gastric accommodation during food intake in healthy volunteers: a single-blind, placebo-controlled study
    Medical condition: study is conducted on healthy volunteers, no medical condition is investigated
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-002623-29 Sponsor Protocol Number: Lundbeckstudy2016 Start Date*: 2016-08-29
    Sponsor Name:Aalborg Universitets Hospital
    Full Title: The Effect of Morphine on the Human Central Nervous System
    Medical condition: Healthy volunteers (Brain response to i.v. morphine)
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-000804-14 Sponsor Protocol Number: OPHT-070119 Start Date*: 2019-05-10
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: The effect of hyperoxia and hypoxia on fluorescence lifetime imaging ophthalmoscopy in healthy subjects
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005534-19 Sponsor Protocol Number: FRIA_FATSURG_1 Start Date*: 2012-01-31
    Sponsor Name:Vrije Universiteit Brussel
    Full Title: The effect of peri-operative anti-inflammatory treatment on postoperative muscle weakness and muscle fatigue in elderly elective surgery patients: a double blinded randomized placebo-controlled trial.
    Medical condition: Post-operative muscle weakness, fatigue and inflammation.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003687-12 Sponsor Protocol Number: RAV1.2 Start Date*: 2017-11-22
    Sponsor Name:Region Ostergotland
    Full Title: Infusion rate and volumekinetics for hyperoncotic albumin in healthy subjects (RAV), - A phase IV, randomized, open-labeled, cross-over study
    Medical condition: Healthy adult volunteers Fluid mobilisation.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2013-003418-42 Sponsor Protocol Number: WOE_2013_TUE Start Date*: 2015-03-23
    Sponsor Name:Wörwag Pharma GmbH & Co. KG
    Full Title: Effect of Mg-Orotate administration on cardiocirculatory Performance, the muscular concentration of phosphocreatine and the adaptation of muscle cellular level: A double blind, randomized, placebo-...
    Medical condition: Evaluation of cardiocirculatory performance using clinical and relevant muscle laboratory parameters while taking Mg-Orotate and application of workouts
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001390-26 Sponsor Protocol Number: PRO-RENAL-REG-064 Start Date*: 2004-11-09
    Sponsor Name:Baxter R&D Europe SCRL
    Full Title: A Subjective Evaluation of Inflow Pain: Comparison of Extraneal to Extraneal Physiological pH
    Medical condition: Patients with End Stage Renal Disease (ESRD) undergoing peritoneal dialysis (PD) therapy and experiencing pain on infusion with Extraneal not related to the catheter or volume of dialysis fluid.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10014646 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-002506-37 Sponsor Protocol Number: SANNI-project:03 Start Date*: 2020-01-08
    Sponsor Name:Region Skane
    Full Title: Dexmedetomidine for analgosedation to newborn infants during neonatal intensive care – a prospective pharmacokinetic/ pharmacodynamic/ pharmacogenetic observational study.Cohort 3 in The SANNI Pr...
    Medical condition: Sick newborn infants in need of intensive care.
    Disease:
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-002717-41 Sponsor Protocol Number: TRAPEZIUS Start Date*: 2023-06-27
    Sponsor Name:HOSPITAL CLINIC DE BARCELONA
    Full Title: EFFICACY AND SAFETY OF LOCAL TREATMENT OF TRAPEZIUS MYOFASCIAL SYNDROME IN PATIENTS WITH FIBROMYALGIA THROUGH ULTRASOUND-GUIDED INTERFASCIAL BLOCK OF THE TRAPEZIUS MUSCLE
    Medical condition: TRAPEZIUS MYOFASCIAL SYNDROME IN FIBROMYALGIA PATIENTS
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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