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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,338 result(s) found. Displaying page 475 of 2,217.
    EudraCT Number: 2009-013286-26 Sponsor Protocol Number: 002 Start Date*: 2010-04-29
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Phase IIb, Randomized, Active Comparator-Controlled, Open-Label Clinical Trial to Study the Efficacy and Safety of MK-2578 for the Treatment of Anemia in ESA (Erythropoiesis-Stimulating Agent)-Na...
    Medical condition: Correction of anemia in ESA-naïve patients with chronic kidney disease (CKD) who are not on dialysis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-013320-23 Sponsor Protocol Number: 030(H)SC09143 Start Date*: 2009-10-14
    Sponsor Name:ANGELINI
    Full Title: A randomized, double-blind, placebo-controlled trial of benzydamine hydrochloride cream in the treatment of plaque psoriasis: a proof-of-concept and dose-finding study
    Medical condition: mild/severe plaque psorias
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040785 SOC
    9.1 10037153 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-013348-35 Sponsor Protocol Number: 7915 Start Date*: 2009-08-04
    Sponsor Name:University Medical Center Utrecht
    Full Title: (Patho)Physiological aspects of the bile salt-FXR-FGF19-axis: potential consequences in Crohn's disease.
    Medical condition: Patients with quiescent Crohn’s colitis, defined as a Crohn’s Disease Activity Index <150 ; non-IBD patients will serve as disease controls.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011400 Crohn's colitis LLT
    9.1 10011401 Crohn's disease LLT
    9.1 10011402 Crohn's disease (colon) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-006443-30 Sponsor Protocol Number: 06-RHY-003 Start Date*: 2007-05-21
    Sponsor Name:Intercytex
    Full Title: A phase IIa open-label study using ICX-RHY to enhance the aesthetic appearance of facial skin imperfections.
    Medical condition: Facial skin imperfections such as small scars, depressions, pock-marks and other localised contour deformities of healthy adults
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002642-32 Sponsor Protocol Number: Protocol No. PR-00908 Start Date*: 2009-01-06
    Sponsor Name:Warner Chilcott UK Limited
    Full Title: A Placebo Controlled, Single-Blind, Pilot Clinical Evaluation of the Effect of a Novel Antibiotic Preparation on the Cutaneous Microflora and Clinical Signs in Acne Patients.
    Medical condition: WC3018 will be indicated for the treatment of of mild to moderate acne vulgaris.
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002650-38 Sponsor Protocol Number: Pre65 Start Date*: 2008-07-01
    Sponsor Name:Organisation name was not entered
    Full Title: Vähentääkö pregabaliini opioidikipulääkityksen tarvetta ja kroonisen kivun esiintyvyyttä alle 65-vuotiailla potilailla sydänleikkauksen jälkeen?
    Medical condition: Tutkimukseen otetaan potilaan suostumuksella alle 65-vuotiaita avosydänleikkauk-seen joko koronaariohitus- tai sydämen läppärekonstruktioon tulevia potilaita, jotka leikatataan perfuusioleikkauksena.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011099 Coronary disease LLT
    9.1 10002906 Aortic stenosis LLT
    9.1 10027716 Mitral insufficiency LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001123-35 Sponsor Protocol Number: IDI-ONC-2-20070220 Start Date*: 2007-11-18
    Sponsor Name:ISTITUTO DERMOPATICO IMMACOLATA
    Full Title: PHASE II STUDY OF DOCETAXEL AND OXALIPLATIN ASSOCIATION AS I LINE THERAPY IN ADVANCED NON SMALL CELL LUNG CANCER (NSCLC) PATIENTS: SCHEDULE-DEPENDENT ACTIVITY AND MOLECULAR TARGETS EVALUATION
    Medical condition: NON SMALL CELL LUNG CANCER (NSCLC)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029521 Non-small cell lung cancer stage IIIB LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-006557-25 Sponsor Protocol Number: RAPYD-STUDY Start Date*: 2007-12-20
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: RAPAMYCIN FOR TREATMENT OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
    Medical condition: ADPKD type I
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038359 Renal and urinary disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006595-11 Sponsor Protocol Number: 07EU/Prg06 Start Date*: 2008-09-25
    Sponsor Name:IBSA Institut Biochimique SA
    Full Title: Efficacy and Tolerability of Subcutaneous Progesterone (IBSA) versus Vaginal Progesterone Gel (Crinone) for Luteal Phase Support in Patients Undergoing In-Vitro Fertilization (IVF).
    Medical condition: Patient undergoing in-Vitro Fertilization (IVF)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021572 In vitro fertilization LLT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed) HU (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-007603-32 Sponsor Protocol Number: 0726 Start Date*: 2008-07-24
    Sponsor Name:CHU de Grenoble
    Full Title: Opothérapie par hydrocortisone après injection unique d'etomidate chez le patient de réanimation
    Medical condition: patients admis en réanimation ayant reçu une injection unique d'etomidate dans le cadre d'une induction en séquence rapide en situation préhospitalière ou au déchocage.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014270-18 Sponsor Protocol Number: CL3-06911-003 Start Date*: 2010-01-13
    Sponsor Name:Laboratorios Servier S.L.
    Full Title: "Eficacia y seguridad de una administración oral diaria de S06911 (combinación fija de ranelato de estroncio 2g / vitamina D3 1000UI) en la deficiencia de vitamina D para el tratamiento de la osteo...
    Medical condition: Osteoporosis en hombres y mujeres postmenopáusicas
    Disease: Version SOC Term Classification Code Term Level
    9 10031283 Osteoporosis fracture LLT
    9 10031285 Osteoporosis postmenopausal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) BE (Completed) DK (Prematurely Ended) SK (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-014275-53 Sponsor Protocol Number: 112267 Start Date*: 2009-10-06
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: An open, single centre study to evaluate the long-term antibody persistence and immune memory between 16 and 20 years after the primary study HAB-028 (208127/021) in which healthy adults were vacc...
    Medical condition: Immunisation of healthy adults with Twinrix Adult
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-001728-30 Sponsor Protocol Number: MPEX-204 Start Date*: 2008-08-26
    Sponsor Name:Mpex Pharmaceuticals, Inc.
    Full Title: A Phase 2, Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability and Efficacy of Three Dosage Regimens of MP- 376 Solution for Inhalation Given for 2...
    Medical condition: Pseudomonas aeruginosa infection in patients suffering from stable Cystic Fibrosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011763 Cystic fibrosis lung LLT
    9.1 10021860 Infection pseudomonas aeruginosa LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-011590-32 Sponsor Protocol Number: CQAX576A2207 Start Date*: 2010-06-22
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A Multi-Center, Randomized, Double Blind, Placebo-Controlled, ‘add-on’ study to investigate the efficacy and safety of 24 weeks intravenous treatment with QAX576 in patients (≥18-75 years) with per...
    Medical condition: persistent moderate to severe asthma patients not adequately controlled with inhaled corticosteroids and long acting β2-agonists
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2009-013036-20 Sponsor Protocol Number: 2009292 Start Date*: 2009-10-15
    Sponsor Name:Rigshospital
    Full Title: Effekten af Gabapentin på urin kateter gener hos patienter med et abdominalt aorta aneurisme som behandles med en endovaskulær stent
    Medical condition: Patienter med et infrarenalt abdominalt aorta aneurisme (AAA) >18 år. KAD i den tidlige postoperative periode medføre smerter/gener med øgning af som opleves værre end smerter sekundært til operati...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-013052-76 Sponsor Protocol Number: VHLSUT09 Start Date*: 2010-02-12
    Sponsor Name:ARTIC (Association pour la Recherche de Thérapeutiques Innovantes en Cancérologie)
    Full Title: A single-arm, phase II study of SU11248 (sunitinib) in patients with von Hippel-Lindau (VHL) disease.
    Medical condition: von Hippel-Lindau (VHL) disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10047716 Von Hippel-Lindau disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009369-32 Sponsor Protocol Number: ENB-003-08 Start Date*: 2009-03-30
    Sponsor Name:Alexion Pharma GmbH
    Full Title: Extension Study of ENB-0040 (Human Recombinant Tissue-Nonspecific Alkaline Phosphatase Fusion Protein) in Severely Affected Infants and Young Children with Hypophosphatasia (HPP)
    Medical condition: Infantile hypoposphatasia
    Disease: Version SOC Term Classification Code Term Level
    19.1 10010331 - Congenital, familial and genetic disorders 10049933 Hypophosphatasia PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-019373-15 Sponsor Protocol Number: 291202BS Start Date*: 2010-06-15
    Sponsor Name:Marinomed Biotechnologie GmbH
    Full Title: A phase IIa, single-center, randomized, reference-controlled, observer-blind trial to assess the efficacy of a topical Aescin formulation in experimentally induced itch, wheal and flare reactions i...
    Medical condition: subjects with proven type I allergy against one of the three allergens: grass pollen, tree pollen, cat epithelia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10036019 Pollen allergy LLT
    12.1 10066093 Birch pollen allergy LLT
    12.1 10001742 Allergy to animal LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022403-22 Sponsor Protocol Number: CLCI699C2201 Start Date*: 2011-07-04
    Sponsor Name:NOVARTIS FARMA
    Full Title: A proof-of concept, open-label, forced titration, multicenter study to assess the safety/tolerability and efficacy of 10-weeks treatment of LCI699 in patients with Cushing’s disease
    Medical condition: Cushing's disease
    Disease: Version SOC Term Classification Code Term Level
    14.0 10014698 - Endocrine disorders 10011652 Cushing's syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022406-41 Sponsor Protocol Number: CPRO400A2201 Start Date*: 2011-09-16
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 3-month, exploratory, non-randomized, multi-center, open label study to evaluate the reliability, safety and usability of the Transplantation Sensor System combined with Myfortic in adult kidney ...
    Medical condition: Maintenance of renal transplantant recipients (>6 months post transplant).
    Disease: Version SOC Term Classification Code Term Level
    14.0 10038359 - Renal and urinary disorders 10023418 Kidney failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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