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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,351 result(s) found. Displaying page 489 of 2,218.
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    EudraCT Number: 2008-003346-28 Sponsor Protocol Number: GIM 200805 Start Date*: 2009-11-11
    Sponsor Name:Landstinget Västmanland, Division Kirurgi, Operationskliniken
    Full Title: Postoperative analgesia with wound catheter och Baxter Infusor after inguinalhernia operation ad modum Lichtenstein with net. Postoperativ smärtlindring med sårkateter och Baxter Infusor efter öppe...
    Medical condition: Postoperative pain relief after inguinalhernia operation ad modum Lichtenstein with net.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003359-58 Sponsor Protocol Number: CPS/04/2008 Start Date*: 2008-09-18
    Sponsor Name:CPS Research
    Full Title: A pilot study to examine the efficacy and safety of escitalopram in doses up to 50 mg for the treatment of patients with Major Depressive Disorder (MDD).
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025453 Major depressive disorder NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012957-39 Sponsor Protocol Number: CLL2P Start Date*: 2010-12-23
    Sponsor Name:University of Cologne
    Full Title: A phase I/II safety and efficacy trial of a combination of bendamustine, rituximab and lenalidomide (BRL) in patients with relapsed or refractory chronic lymphocytic leukemia
    Medical condition: Patients (age 18 or older) with relapsed or refractory chronic lymphocytic leukemia requiring treatment
    Disease: Version SOC Term Classification Code Term Level
    12.1 10008976 Chronic lymphocytic leukemia LLT
    12.1 10008977 Chronic lymphocytic leukemia recurrent LLT
    12.1 10008978 Chronic lymphocytic leukemia refractory LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001346-33 Sponsor Protocol Number: GS-US-103-0518 Start Date*: Information not available in EudraCT
    Sponsor Name:Gilead Sciences Inc
    Full Title: A Phase 3 Double-Blind Randomised, Placebo-Controlled Study of the safety and Efficacy of Adefovir Dipivoxil in Children and Adolescents (Age 2to <18) with Chronic Hepatitis B
    Medical condition: Chronic Hepatitis B
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-000960-25 Sponsor Protocol Number: 2005/R/CAR/04 Start Date*: 2005-04-29
    Sponsor Name:Lothian NHS trust
    Full Title: Role of Inflammation and Platelet Activation in the adverse Cardiovascular Outcomes of Patients with Critical Limb Ischaemia - a double-blind randomised trial of Clopidogrel.
    Medical condition: Peripheral Vascular Disease (Critical Limb Ischaemia)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-006238-87 Sponsor Protocol Number: 4717 Start Date*: 2010-01-22
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: Improving the safety and efficacy of anticoagulation therapy for thromboembolic disease through vitamin K
    Medical condition: Patients will be recruited who are receiving long term warfarin therapy for the treatment or prevention of venous or arterial thrombosis or embolism
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-011187-11 Sponsor Protocol Number: ACROSS-2009-01 Start Date*: 2009-09-07
    Sponsor Name:ACROSS
    Full Title: “Estudio fase III multicéntrico, aleatorizado y abierto de dos pautas de hierro intravenoso en combinación con epoetina beta para el tratamiento de la anemia inducida por quimioterapia en pacientes...
    Medical condition: ANEMIA EN PACIENTES ADULTOS CON TUMORES NO MIELOIDES EN TRATAMIENTO CON QUIMIOTERAPIA
    Disease: Version SOC Term Classification Code Term Level
    9 10054310 Anemia of chronic disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000765-33 Sponsor Protocol Number: AGMT_NSCLC 1 Start Date*: 2009-11-19
    Sponsor Name:AGMT gemeinnützige GmbH
    Full Title: Phase II Study to Investigate the Treatment of Patients with NSCLC Stage IIIB and IV without the Option of Surgery with a Combination of Cisplatin, Docetaxel and Bevacizumab
    Medical condition: Inoperable NSCLC, stages IIIB and IV
    Disease: Version SOC Term Classification Code Term Level
    12.0 10029521 Non-small cell lung cancer stage IIIB LLT
    12.0 10029522 Non-small cell lung cancer stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-001382-15 Sponsor Protocol Number: ATI-2042-CLN-205 Start Date*: 2007-09-20
    Sponsor Name:ARYx Therapeutics
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Study of ATI-2042 in Patients with Paroxysmal Atrial Fibrillation and Pacemakers with Atrial Fibrillation Data Logging Capabilities
    Medical condition: The trial is to investigate the efficacy of the new drug ATI-2042 to reduce the atrial tachyarrhythmia burden in patients with paroxysmal atrial fabrilation. ATI-2042 is designed to act like Amioda...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003661 Atrial fibrillation paroxysmal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001403-38 Sponsor Protocol Number: V44P11S Start Date*: 2007-05-10
    Sponsor Name:Novartis Vaccines and Diagnostics GmbH & Co. KG
    Full Title: A Phase III, multicenter, uncontrolled, open-label study to evaluate safety and immunogenicity of Begrivac®, preservative free, inactivated split influenza vaccine, using the strain composition 200...
    Medical condition: No medical condition, healthy volunteers will be recruited into clinical trial for annual approval of influenza vaccine with the new strain composition according WHO and EMEA recommendation and CPM...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-011751-46 Sponsor Protocol Number: IC 2009-01 Start Date*: 2009-10-06
    Sponsor Name:INSTITUT CURIE
    Full Title: Etude de phase II monocentrique associant Bevacizumab et Temozolomide chez des patients atteints de mélanome uvéal en première ligne métastatique.
    Medical condition: Mélanome uvéal métastatique.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027151 Melanoma of choroid LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014741-89 Sponsor Protocol Number: 0916202 Start Date*: 2009-10-20
    Sponsor Name:Centre Hospitalier de Toulouse
    Full Title: Recherche de la DE90 d'un bolus de sufentanil pour l'analgésie des soins douloureux de nursing des malades intubés de réanimation
    Medical condition: patients intubés en réanimation sous ventilation mécanique
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014742-28 Sponsor Protocol Number: ANRS147 Start Date*: 2009-11-18
    Sponsor Name:Agence nationale de recherches sur le sida et les hépatites virales ANRS
    Full Title: Essai randomisé multicentrique de phase III évaluant chez des patients en primo-infection VIH-1 l’impact sur les réservoirs (par quantification de l’ADN-VIH-1 dans les PBMC) d’une combinaison compr...
    Medical condition: Primo infection VIH-1
    Disease: Version SOC Term Classification Code Term Level
    12.0 10058427 Primary HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014373-41 Sponsor Protocol Number: H135 Start Date*: 2010-02-12
    Sponsor Name:NHS Greater Glasgow and Clyde
    Full Title: A randomised Phase II trial of Imatinib (IM) versus Hydroxychloroquine (HCQ) and Imatinib (IM) for patients with Chronic Myeloid Leukaemia (CML) in Cytogenetic Response (CyR) with residual disease ...
    Medical condition: Chronic Myeloid Leukaemia
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10009013 Chronic myeloid leukaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-012847-40 Sponsor Protocol Number: Pergoveris_Cetrorelix_1 Start Date*: 2009-11-11
    Sponsor Name:NHS Lothian [...]
    1. NHS Lothian
    2. The University of Edinburgh
    Full Title: A Randomised Study Comparing Two Different Regimens of Ovarian Stimulation Using Pergoveris and Cetrorelix for Controlled Ovarian Superovulation in Assisted Conception Treatment.
    Medical condition: Subfertility
    Disease: Version SOC Term Classification Code Term Level
    12. 10042391 Subfertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-018038-12 Sponsor Protocol Number: P05897 Start Date*: 2011-10-18
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: A 26-week, multi-center, open-label, flexible dose, long-term safety trial of asenapine in adolescent subjects with schizophrenia
    Medical condition: Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10039626 Schizophrenia LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: RO (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2008-001872-54 Sponsor Protocol Number: ARC1779−006 Start Date*: 2009-01-24
    Sponsor Name:Archemix Corp
    Full Title: A Randomized, Double−blind, Placebo−controlled, Clinical Outcome Study of ARC1779 Injection in Patients with Thrombotic Microangiopathy.
    Medical condition: Thrombotic microangiopathy (TMA) disorders
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009731 Coagulation disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) AT (Prematurely Ended) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001886-26 Sponsor Protocol Number: TRI-002-INT Start Date*: 2010-06-29
    Sponsor Name:GALENICA S.A.
    Full Title: A multicenter, double-blind, randomized, placebo controlled phase III study of the efficacy and safety of Trimebutine 300 mg twice daily for the relief of functional dyspeptic patients
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017026-39 Sponsor Protocol Number: UCBT-002 Start Date*: 2009-12-28
    Sponsor Name:Aldagen, Inc
    Full Title: A PHASE III TRIAL OF ALD-101 ADUVANT THERAPY of UNRELATED UMBILICAL CORD BLOOD TRANSPLANTATION (UCBT) IN PATIENTS WITH INBORN ERRORS OF METABOLISM
    Medical condition: Inborn errors of metabolism
    Disease: Version SOC Term Classification Code Term Level
    9.1 10062018 Inborn error of metabolism LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017032-41 Sponsor Protocol Number: AI424-402 Start Date*: 2011-08-01
    Sponsor Name:Bristol Myers Squibb International Corporation
    Full Title: An Open-Label, Randomized Study Evaluating a Switch from a Regimen of Two Nucleoside Reverse Transcriptase Inhibitors plus any Third Agent to either a Regimen of Atazanavir/Ritonavir Once Daily and...
    Medical condition: HIV-1 infected subjects who are virologically suppressed on a regimen of 2 NRTIs plus any 3rd agent, but experience safety and/or tolerability issues to this regimen.
    Disease: Version SOC Term Classification Code Term Level
    15.0 10021881 - Infections and infestations 10068341 HIV-1 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed) PL (Completed) IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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