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Clinical trials for Healthy Volunteer

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    199 result(s) found for: Healthy Volunteer. Displaying page 5 of 10.
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    EudraCT Number: 2012-003090-26 Sponsor Protocol Number: 110401 Start Date*: 2013-03-25
    Sponsor Name:TECNIMEDE ? SOCIEDADE TÉCNICO MEDICINAL S.A.
    Full Title: STUDY TO EVALUATE THE PROPORTIONALITY OF 3 ORAL DOSES OF PIRLINDOLE IN HEALTHY VOLUNTEERS.
    Medical condition: Not applicable (including healthy volunteers).
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-004129-89 Sponsor Protocol Number: Motor-Neuromod_01, Part I-III Start Date*: 2005-09-19
    Sponsor Name:Universitätsklinikum Münster
    Full Title: Potentiation of procedural motor learning by pharmacological neuromodulation and brain stimulation
    Medical condition: Healthy volunteers Patients in the chronic stage (> 1 year) after stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002795-96 Sponsor Protocol Number: CBFH772A2201 Start Date*: 2008-12-11
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A single center, phase I, partially blinded, placebo-controlled, first-in-man study to evaluate the safety, tolerability and Proof of Mechanism (PoM) of a single administration of BFH772 in healthy...
    Medical condition: Plaque psoriasis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037153 Psoriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001265-92 Sponsor Protocol Number: VAC065 Start Date*: 2016-06-24
    Sponsor Name:University of Oxford, CTRG
    Full Title: A Phase I/IIa Sporozoite Challenge Study to Assess the Safety and Protective Efficacy of adjuvanted R21 at different doses and the Combination Malaria Vaccine Candidate Regimen of adjuvanted R21 + ...
    Medical condition: Plasmodium falciparum infection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-002383-27 Sponsor Protocol Number: CHDR1806 Start Date*: 2019-08-01
    Sponsor Name:Centre for Human Drug Research
    Full Title: An exploratory, single-center, double-blinded, healthy volunteer controlled study to characterize psoriasis patients and explore novel biomarkers for the treatment response of psoriasis with a mult...
    Medical condition: Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10037153 Psoriasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-005470-41 Sponsor Protocol Number: CTR0028 Start Date*: 2006-11-16
    Sponsor Name:Regent Medical
    Full Title: Hibiscrub EN12791 Testing using current application and 2 new application methods
    Medical condition: This trial will be carried out on healthy volunteers. Hibiscrub is a 4% chlorhexidine glucnate based pre-operative surgical hand disinfectant. Volunteers are going to use the product in three dif...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000232-12 Sponsor Protocol Number: SYNC-01-AC-P1 Start Date*: 2007-01-31
    Sponsor Name:Syntopix Group plc
    Full Title: Novel topical therapies for acne vulgaris: a randomised, controlled, double blind comparison of the antibacterial efficacy of 1% w/v formulations of tert-butylhydroquinone, zinc pyrithione and benz...
    Medical condition: Healthy volunteer study. The product under development will be used for the treatment of acne vulgaris.
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016855-23 Sponsor Protocol Number: CD09/9088 Start Date*: 2010-08-20
    Sponsor Name:University of Leeds
    Full Title: Targeting systemic inflammation to improve endothelial function in obesity
    Medical condition: Healthy volunteer trial in obese subjects (body mass index 30 or greater) in which the IMP will be used to reduce inflammation by inhibiting tumour necrosis factor(TNF)-α in order to assess the eff...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015175-27 Sponsor Protocol Number: NVI-250 Start Date*: 2010-02-16
    Sponsor Name:Netherlands Vaccine Institute
    Full Title: Immunogenicity and safety of intradermal injection of reduced dose Inactivated Poliovirus vaccine (IPV) with a jet injector in healthy adults
    Medical condition: The vaccine in this healthy volunteer trial is indicated to prevent poliomyelitis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-004833-17 Sponsor Protocol Number: CBD VP 128/05 Start Date*: 2009-05-01
    Sponsor Name:Dstl
    Full Title: Assessment of the effect of prior anthrax vaccine precipitated (AVP) vaccination on the immune response to booster AVP vaccination.
    Medical condition: Vaccination against potential exposure to anthrax (Bacillus anthracis).
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008954-22 Sponsor Protocol Number: APOMST003 Start Date*: 2009-10-27
    Sponsor Name:Medisch Spectrum Twente
    Full Title: Non Steroidal Anti-Inflammatory Drugs and the antiplatelet effects of acetylsalicylic acid
    Medical condition: This is a healthy volunteer trial. Indications of the IMP's in the context of this trial are: Elevated risk on cardiovascular event Rheumatoid arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024649-61 Sponsor Protocol Number: POXY11 Start Date*: 2011-04-05
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Pilot study: performance of the Progensa PCA3 test in post-oxytocin urine specimens
    Medical condition: Healthy volunteer trial: intended indication for product is to mobilize prostate cells in urethra for PCA3 test.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10033329 Oxytocin PT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-004360-44 Sponsor Protocol Number: VAC034 Start Date*: 2008-04-29
    Sponsor Name:University of Oxford
    Full Title: Assessment of protection against malaria by sporozoite challenge of healthy adults vaccinated with AdCh63 ME-TRAP and MVA ME-TRAP
    Medical condition: Malaria
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-000826-39 Sponsor Protocol Number: S-20130165 Start Date*: 2014-06-17
    Sponsor Name:Ortopædkirurgisk afdeling Odense Universitetshospital
    Full Title: Determining the tissue concentration of dicloxacillin using Microdialysis (on healthy male subjects)
    Medical condition: The trial is conducted on healthy male volunteers. An intravenous dose of 2 grams of dicloxacillin is administered intravenously and the muscle- and subcutaneous tissue concentrations are measured ...
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004862 10059428 Postoperative infection LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2020-005842-41 Sponsor Protocol Number: 20-687 Start Date*: 2021-01-22
    Sponsor Name:KRKA, d.d., Novo mesto
    Full Title: COMPARATIVE, RANDOMISED, SINGLE-DOSE, CROSSOVER, 3-WAY BIOAVAILABILITY STUDY OF DAPAGLIFLOZIN 10 mg FORMULATIONS IN HEALTHY VOLUNTEERS UNDER FED CONDITIONS
    Medical condition: Healthy voluneers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001974-11 Sponsor Protocol Number: HEPATOTEST Start Date*: 2013-08-29
    Sponsor Name:INSTITUTO DE INVESTIGACION SANITARIA LA FE
    Full Title: PILOT TRIAL FOR THE EVALUATION OF HEPATOTEST IN PREOPERATIVE ASSESSMENT IN LIVER FUNCTION.
    Medical condition: Patients with liver metastases (mainly colorectal cancer) who will be undergoing major hepatic resection (3 or more liver segments) which have been treated with neoadjuvant chemotherapy.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001518-40 Sponsor Protocol Number: LPS16764 Start Date*: 2020-12-15
    Sponsor Name:Sanofi Aventis Recherche & Developpement
    Full Title: Open-label exploratory study to evaluate the effect of dupilumab on skin barrier function in pediatric patients with moderate to severe atopic dermatitis
    Medical condition: Atopic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10012438 Dermatitis atopic PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2017-001075-23 Sponsor Protocol Number: VAC066 Start Date*: 2018-09-05
    Sponsor Name:University of Oxford, CTRG
    Full Title: A Phase I/IIa Sporozoite Challenge Study to assess the safety, immunogenicity and protective efficacy of intravenous boosting with malaria vaccine candidates ChAd63 and MVA encoding ME-TRAP
    Medical condition: Plasmodium falciparum infection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-001015-14 Sponsor Protocol Number: VAC18195RSV1001 Start Date*: 2022-10-05
    Sponsor Name:Janssen Vaccines & Prevention B.V.
    Full Title: A Randomized, Double-blind, Placebo-controlled Phase 1/2a Study for Safety and Immunogenicity Evaluations of various RSV.preF-based Vaccine Formulations in Adults Aged 60 Years and Older
    Medical condition: Healthy volunteer (prevention of lower respiratory tract disease caused by respiratory syncytial virus (RSV))
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-004860-37 Sponsor Protocol Number: 280312BS Start Date*: Information not available in EudraCT
    Sponsor Name:Arcutis Pharmaceuticals
    Full Title: A phase IIIb/IV, single-center, randomized, controlled, observer-blind study to assess the effects of topical formulations containing clindamycin-benzoyl peroxide on epidermal functions in subjects...
    Medical condition: Healthy volunteer trial to investigate the effects of IDP-110 Gel compared to two marketed products containing cindamycin-benzoyl peroxide on epidermal functions
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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