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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,393 result(s) found. Displaying page 591 of 2,220.
    «« First « Previous 587  588  589  590  591  592  593  594  595  Next» Last»»
    EudraCT Number: 2004-000646-20 Sponsor Protocol Number: C04-001 Start Date*: 2004-09-21
    Sponsor Name:ALEXION PHARMACEUTICALS INCORPORATED
    Full Title: A Hemoglobin Stabilization and Transfusion Reduction Efficacy and Safety Clinical Investigation, Randomized, Multi-Center, Double-Blind, Placebo-Controlled, Using Eculizumab in Paroxysmal Nocturnal...
    Medical condition: paroxysmal nocturnal hemoglobinuria
    Disease: Version SOC Term Classification Code Term Level
    7.0 10034042 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) IE (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000649-39 Sponsor Protocol Number: EMR62202-502 Start Date*: 2004-12-01
    Sponsor Name:Merck KGaA
    Full Title: A randomized, controlled, multicenter, phase I/II study of cetuximab plus irinotecan investigating the pharmacodynamics, genomics and -genetics as well as the safety and efficacy of a dose escalat...
    Medical condition: Metastatic colorectal cancer refractory to irinotecan treatment
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000675-34 Sponsor Protocol Number: EU 101 Start Date*: 2004-12-21
    Sponsor Name:University Medical Center Utrecht
    Full Title: A Prospective, Randomized, Controlled, Multi-center, (Pilot) Study of Osigraft® in Instrumented Posterolateral Fusions
    Medical condition: Subjects qualifying for decompression and fusion of one spinal level (L3-S1) with the use of autograft will be recruited through the medical institutions of participating investigators. All subject...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000677-62 Sponsor Protocol Number: CVAA489A2306 Start Date*: 2004-09-06
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, double-blind, multicenter, active-controlled, parallel design trial to evaluate the safety and efficacy of the combination of valsartan/amlodipine 160/10 mg versus amlodipine 10 mg al...
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) HU (Completed) LT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000678-30 Sponsor Protocol Number: PRO-RENAL-REG-056 Start Date*: 2004-11-22
    Sponsor Name:Baxter Healthcare S.A.
    Full Title: An Evaluation of the Efficacy of Epo-Omega in Treatment of Anaemia in ESRD Patients When Administered by Thrice Weekly Intravenous Injection: A Dose Dependency Evaluation.
    Medical condition: Anaemia in End Stage Renal Disease (ESRD) hemodialyzed Patients
    Disease: Version SOC Term Classification Code Term Level
    7.0 10009120 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2004-002812-27 Sponsor Protocol Number: CEP-1347-201 Start Date*: 2005-05-04
    Sponsor Name:deCODE genetics ehf.
    Full Title: A prospective, randomised, double-blind, placebo-controlled, parallel group dose ranging study in asthma patients in Iceland to assess the safety, tolerability and efficacy of the MLK inhibitor, CE...
    Medical condition: Asthma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IS (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002823-42 Sponsor Protocol Number: A00401 Start Date*: 2005-05-02
    Sponsor Name:UCB S.A. Pharma Sector
    Full Title: A multicentre, double-blind, parallel, randomized, placebo-controlled study : Evaluation of the efficacy and safety of Levocetirizine 5 mg and Desloratadine 5 mg administered orally as capsules onc...
    Medical condition: Allergic Rhinitis (AR)
    Disease: Version SOC Term Classification Code Term Level
    7.1 10001723 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002079-18 Sponsor Protocol Number: FG-506-17-07 Start Date*: 2004-11-01
    Sponsor Name:Fujisawa GmbH
    Full Title: A MULTICENTRE, RANDOMISED, DOUBLE BLIND, DOUBLE- DUMMY PARALLEL-GROUP STUDY INVESTIGATING THE EFFICACY AND SAFETY OF THREE DIFFERENT DOSES OF TACROLIMUS INHALATION AEROSOL AND A STANDARD DOSE OF ...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    7.0 10003553 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2004-004434-14 Sponsor Protocol Number: FFR103184 Start Date*: 2005-04-05
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A randomized, double-blind, placebo-controlled, parallel group, multicenter two week study to evaluate the efficacy and safety of once-daily, intranasal administration of GW685698X aqueous nasal sp...
    Medical condition: Seasonal allergic rhinitis (SAR)
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) LT (Completed) EE (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2004-002173-23 Sponsor Protocol Number: GD3-134-201 Start Date*: 2004-11-09
    Sponsor Name:GENZYME
    Full Title: PHASE 2 CLINICAL STUDY PROTOCOL: SAFETY AND EFFICACY OF RISING DOSES OF DEFERITRIN IN BETA-THALASSEMIA PATIENTS
    Medical condition: Patients with iron overload secondary to beta-thalassemia
    Disease: Version SOC Term Classification Code Term Level
    10043391 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-002197-34 Sponsor Protocol Number: 04/Q1104/27 Start Date*: 2004-12-14
    Sponsor Name:University College London
    Full Title: A phase III multicentre randomised clinical trial comparing rituximab with CHOP given every 14 days and rituximab with CHOP given every 21 days for the treatment of patients with newly diagnosed d...
    Medical condition: Newly diagnosed diffuse large B cell non-Hodgkin's lymphoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001965-16 Sponsor Protocol Number: 101-AC-OSL-124 Start Date*: 2005-01-26
    Sponsor Name:LABORATORIOS LETI
    Full Title: ENSAYO CLÍNICO, MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO CONTROLADO CON PLACEBO, DE INMUNOTERAPIA SUBLINGUAL CON EXTRACTO ALERGÉNICO DE DERMATOPHAGOIDES PTERONYSSINUS EN PACIENTES CON ASMA, DE INTE...
    Medical condition: La inmunoterapia consiste en la administración, generalmente subcutánea, de dosis progresivamente crecientes del material alergénico al que el paciente está sensibilizado, con el fin de mejorar la ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001966-41 Sponsor Protocol Number: 6043-AC-OSL-123 Start Date*: 2005-01-19
    Sponsor Name:LABORATORIOS LETI
    Full Title: ENSAYO CLÍNICO, MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO CONTROLADO CON PLACEBO, DE INMUNOTERAPIA SUBLINGUAL CON EXTRACTO DE POLEN DE PHLEUM PRATENSE EN PACIENTES CON HIPERSENSIBILIDAD AL POLEN DE ...
    Medical condition: La inmunoterapia consiste en la administración, generalmente subcutánea, de dosis progresivamente crecientes del material alergénico al que el paciente está sensibilizado, con el fin de mejorar la ...
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001967-24 Sponsor Protocol Number: L 9259 Start Date*: 2004-09-22
    Sponsor Name:Sanofi-Synthelabo Rt.
    Full Title: Kiegészítő zolpidem kezelés friss antidepresszáns kezelés alatt álló disztimiás vagy depressziós betegek alvászavarának kezelésében
    Medical condition: A depresszióban szenvedő betegek alvászavarára jellemzően megfigyelhető kóros alvásparaméterek lehetnek az elalvás nehezítettsége, töredezett, felszínes alvás gyakori felébredésekkel, az újra elalv...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2005-000403-33 Sponsor Protocol Number: GEICAM/2004-04 Start Date*: 2005-06-01
    Sponsor Name:GRUPO ESPAÑOL DE INVESTIGACIÓN EN CÁNCER DE MAMA (GEICAM)
    Full Title: Randomized clinical trial to evaluate the predictive accuracy of a gene expression profile-based test to select patients for preoperative taxane/anthracycline chemotherapy for stage I-III breast ca...
    Medical condition: Patients with histologically confirmed stage I-III invasive carcinoma of the breast for whom adjuvant chemotherapy is indicated.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000083-27 Sponsor Protocol Number: GT-08 Start Date*: 2004-09-19
    Sponsor Name:ALK-Abelló A/S
    Full Title: A randomised, parallel-group, double-blind, placebo-controlled Phase III trial assessing the efficacy and safety of ALK Grass Tablet Phleum pratense in subjects with seasonal grass pollen induced r...
    Medical condition: Rhinoconjunctivitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) IT (Completed) ES (Completed) AT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001608-11 Sponsor Protocol Number: SPD405-310 Start Date*: 2004-11-18
    Sponsor Name:Shire Pharmaceutical Development Ltd
    Full Title: A Multi-centre, Open Label, Randomised, Parallel Group Pilot Study to assess the Efficacy and Safety of Lanthanum Carbonate and Sevelamer Hydrochloride in Patients Receiving Haemodialysis for End S...
    Medical condition: Hyperphosphataemia in Patients Receiving Haemodialysis for End Stage Renal Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-003771-37 Sponsor Protocol Number: Hx-CD20-403 Start Date*: 2006-03-03
    Sponsor Name:Genmab A/S
    Full Title: A double-blind, randomized, placebo controlled, dose escalation, multi-center phase I/II trial of HuMax-CD20, a fully human monoclonal anti-CD20 antibody, in patients with active rheumatoid arthrit...
    Medical condition: Active Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10039073 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2004-000990-78 Sponsor Protocol Number: 10413 Start Date*: 2004-10-04
    Sponsor Name:H. Lundbeck A/S
    Full Title: A Double-Blind, Multicentre, Randomised, Parallel-group, Placebo-controlled Study Assessing the Efficacy and Safety of Escitalopram in Post-Myocardial Infarction Patients Suffering from Depressive ...
    Medical condition: Depressive symptoms in post myocardial infarction patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) AT (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2004-001035-32 Sponsor Protocol Number: ISG-STS 04/03 Start Date*: 2004-05-13
    Sponsor Name:ITALIAN SARCOMA GROUP
    Full Title: NON-MYELOABLATIVE ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION FROM HLA IDENTICAL SIBLING FOR METASTATIC SOFT TISSUE SARCOMAS
    Medical condition: METASTATIC SOFT TISSUE SARCOMAS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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