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Clinical trials for Heart surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    628 result(s) found for: Heart surgery. Displaying page 7 of 32.
    «« First « Previous 3  4  5  6  7  8  9  10  11  Next» Last»»
    EudraCT Number: 2012-001983-31 Sponsor Protocol Number: 1842012 Start Date*: 2012-05-25
    Sponsor Name:Juha Hartikainen
    Full Title:
    Medical condition: Coronary artery by-pass surgery patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10011076 Coronary artery atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005985-33 Sponsor Protocol Number: 402-C-319 Start Date*: 2020-12-16
    Sponsor Name:Pacira Pharmaceuticals, Inc.
    Full Title: A Multicenter Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postsurgical Analgesia in Pediatric Subjects Aged 6 to Less Than 17 Years
    Medical condition: Postsurgical pain
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-002756-21 Sponsor Protocol Number: 1663/2020 Start Date*: 2021-02-23
    Sponsor Name:Department of Cardiothoracic Anesthesia and Intensive Care Medicine, Medical University of Vienna
    Full Title: Plasma Pharmacokinetics of Prophylactic Cefazolin Administered for Cardiac Surgery: Comparison of Cardiopulmonary Bypass Priming with Additive Human Albumin 20% vs.Pure Crystalloid Priming: A singl...
    Medical condition: This is a pharmacokinetic trial for patients undergoing cardiac surgery. It will be investigated whether cardiopulmonary bypass priming substituted with human albumin 20% has an effect on the pharm...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-005370-11 Sponsor Protocol Number: SR12/2014 Start Date*: 2015-05-04
    Sponsor Name:University Hospitals Leuven
    Full Title: Xenon for the prevention of postoperative delirium in cardiac surgery: Aprosptective randomized controlled trial
    Medical condition: Xenon anesthesia in cardiac surgery
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-001806-32 Sponsor Protocol Number: ARG-01 Start Date*: 2021-12-14
    Sponsor Name:Sahlgrenska University Hospital
    Full Title: Influence of Argipressin on blood loss and inflammatory response during hepatic resection; a double blinded, randomized, placebo-controlled trial
    Medical condition: Hepatic resection due to primary malignant disease, metastasis or benign tumour
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10019701 Hepatic neoplasm malignant resectable LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-004191-35 Sponsor Protocol Number: AGO/2013/011 Start Date*: 2014-11-28
    Sponsor Name:Ghent University Hospital
    Full Title: Evaluation of the effects and plasma concentration of the potent platelet inhibitor ticagrelor, after crushed and non-crushed intake, after semi-urgent coronary bypass and in patients after cardiac...
    Medical condition: Group A: Patients who received CPR because of cardiac arrest. Group B: Patients in need of semi-urgent coronary bypass surgery, allowing interrupting the administration of ticagrelor 3 days before ...
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10063919 Bypass surgery LLT
    17.1 10007541 - Cardiac disorders 10007515 Cardiac arrest PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-001645-12 Sponsor Protocol Number: ALPHA2PREVENT Start Date*: 2021-06-28
    Sponsor Name:Oslo University Hospital
    Full Title: Alpha 2 adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): randomised controlled trial.
    Medical condition: Postoperative delirium and cognitive decline in male and female participants aged 70+ scheduled for open heart surgery
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-004141-90 Sponsor Protocol Number: 4.0 Start Date*: 2017-02-28
    Sponsor Name:Queen Mary University of London
    Full Title: Stopping Perioperative Angiotensin II Converting Enzyme inhibitors and/or receptor blockers in major non-cardiac surgery (SPACE): a phase II, explanatory, randomised controlled trial.
    Medical condition: Myocardial injury (as measured by plasma troponin) after major surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10061024 Cardiac disorder PT
    20.0 10007541 - Cardiac disorders 10061024 Cardiac disorder PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2013-001922-24 Sponsor Protocol Number: 120541 Start Date*: 2013-07-12
    Sponsor Name:University College London (UCL)
    Full Title: The effect of remote ischaemic preconditioning and glyceryl trinitrate on peri-operative myocardial injury in cardiac bypass surgery patients (ERIC-GTN study)- a four arm randomised controlled trial
    Medical condition: We are investigating the phenomenon of ischaemic-reperfusion injury. Reperfusion of the ischaemic myocardium is known to cause further myocardial damage. We wish to investigate the phenomenon of Re...
    Disease: Version SOC Term Classification Code Term Level
    16.0 10007541 - Cardiac disorders 10051624 Myocardial reperfusion injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001265-41 Sponsor Protocol Number: 200621 Start Date*: 2006-06-16
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Trust
    Full Title: A comparison of Sirolimus versus Tacrolimus as a delayed treatment of recipients of non heart beating donor kidneys after anti-IL2 monoclonal antibody
    Medical condition: Kidney transplantation from non heart beating donors for end-stage renal disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005701-43 Sponsor Protocol Number: PROP-001-CP3 Start Date*: 2013-04-11
    Sponsor Name:Fresenius Kabi Deutschland GmbH
    Full Title: Therapeutic Equivalence Study of Propofol Using Target-Controlled Infusion of Propofol 2% (20 mg/mL) MCT Fresenius Compared with Diprivan® 20 mg/mL (AstraZeneca) in Patients Undergoing Elective Sur...
    Medical condition: Elective minor Surgery
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2016-001584-36 Sponsor Protocol Number: 2014-03-11 Start Date*: 2016-06-01
    Sponsor Name:Universitetssjukhuset Örebro
    Full Title: Is high oxygen concentration a riskfactor for postoperative complications? A prospective, randomized, singel blinded study in elderly patients undergoing vascular surgery
    Medical condition: Elective vascular surgery (peripheral vascular and aortic surgery)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001505-90 Sponsor Protocol Number: 18CH049 Start Date*: 2018-10-01
    Sponsor Name:CHU de Saint Etienne
    Full Title: Decolonization of patients carrying S. aureus before cardiac surgery: study of the risk factors associated with failure
    Medical condition: Decolonization of S. aureus nasal carriers before cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10075981 Staphylococcus aureus infection LLT
    20.0 100000004865 10048935 Open heart surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022579-68 Sponsor Protocol Number: COR-1/02 Start Date*: 2011-08-16
    Sponsor Name:Corimmun GmbH
    Full Title: COR-1, an anti-ß1 receptor antibody cyclopeptide in heart failure: a phase II, multicentre, randomised, double-blind and placebo-controlled study with parallel groups
    Medical condition: Heart Failure, Dilated Cardiomyopathy
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10056419 Dilated cardiomyopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005559-17 Sponsor Protocol Number: ACA-SPAI-12-07 Start Date*: 2013-04-22
    Sponsor Name:Rosa Herrera Castro
    Full Title: Hemodynamic consequences of isobaric levobupivacaine versus hyperbaric bupivacaine for spinal anesthesia in patients over 65 years, underwent hip surgery
    Medical condition: In patients 65 years or older undergoing hip surgery.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10051060 Hip surgery PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003113-26 Sponsor Protocol Number: CoLeBu Start Date*: 2018-05-09
    Sponsor Name:ROSA HERRERA CASTRO
    Full Title: Hemodynamic safety of isobaric levobupivacaine versus isobaric bupivacaine for spinal anesthesia in patients over 65 years, underwent hip surgery.
    Medical condition: In patients 65 years or older undergoing hip surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10051060 Hip surgery PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002409-23 Sponsor Protocol Number: 2012/421 Start Date*: 2012-09-21
    Sponsor Name:Aarhus University Hospital
    Full Title: Coagulation Profile in Patients Undergoing Video Assisted Thoracoscopic Surgery (VATS) for lung cancer - a randomized, controlled trial
    Medical condition: Coagulation profile in patients undergoing lung surgery due to cancer in the lung.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006480-23 Sponsor Protocol Number: 10,176 Start Date*: 2007-10-12
    Sponsor Name:University Hospitals of Leicester
    Full Title: Autologous Bone Marrow-Derived Cells for Cardioprotection During Heart Surgery
    Medical condition: Improvement of cardioprotection during elective coronary artery bypass graft surgery using the patients own bone marrow cells.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-001056-22 Sponsor Protocol Number: NDOL-001-2016 Start Date*: 2016-08-24
    Sponsor Name:Medical Univerity Vienna
    Full Title: Neodolpasse® Infusion Solution versus diclofenac 75 mg infusion in the treatment of postoperative pain after elective knee surgery - an exploratory placebo-controlled clinical study to investigate ...
    Medical condition: major elective knee surgery (cruciate ligament surgery)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-004465-32 Sponsor Protocol Number: 2011/386 Start Date*: 2011-12-12
    Sponsor Name:Dept. of Cardiothoracic & Vascular Surgery, Aarhus University Hospital, Skejby
    Full Title: Can post-operative treatment with parathyroid hormone enhance bone healing and quality of newly formed bone after sternotomy in cardiac surgery patients?
    Medical condition: Sternotomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10051332 Surgical procedure LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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