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Clinical trials for Necrosis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    422 result(s) found for: Necrosis. Displaying page 7 of 22.
    EudraCT Number: 2006-004715-22 Sponsor Protocol Number: VX06-702-304 Start Date*: 2006-10-26
    Sponsor Name:Vertex Pharmaceuticals Incorporated
    Full Title: A Phase 2, 12-Week, Randomized, Placebo-Controlled Study to Evaluate the Antiinflammatory Effects of VX-702 when Administered Concomitantly with Methotrexate
    Medical condition: Rheumatoid Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2014-005369-64 Sponsor Protocol Number: iBEAST/2 Start Date*: 2015-06-19
    Sponsor Name:Consorci MAr Parc de Salut de Barcelona
    Full Title: Improve the myocardial reperfusion in ST elevation myocardial infarction: a randomized study between standard percutaneous coronary intervention with thrombectomy and pharmacological approach guide...
    Medical condition: ST elevation myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003731-20 Sponsor Protocol Number: HODIVA Start Date*: 2008-10-21
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Postoperative Hyperbaric Oxygen treatments to reduce complications in Diabetic patients undergoing Vascular Surgery (HODIVA) - A double blind, randomized controlled study
    Medical condition: Postoperative complications after vascular surgery in the leg. This includes wound infections, wound dehiscience and necrosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057480 Hyperbaric oxygen therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013622-17 Sponsor Protocol Number: REMEDY Start Date*: 2009-10-20
    Sponsor Name:CARDIOLOGIA UNIVERSITARIA - OSPEDALE CLINICIZZATO SS. ANNUNZIATA - VIA DEI VESTINI - 66013 CHIETI
    Full Title: ROSUVASTATIN FOR REDUCTION OF MYOCARDIAL DAMAGE AND SYSTEMIC INFLAMMATION DURING CORONARY ANGIOPLASTY - The REMEDY Study
    Medical condition: In patients with suspected stable CAD candidates to PCI
    Disease: Version SOC Term Classification Code Term Level
    12.1 10011085 Ischaemic coronary artery disorders HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006562-42 Sponsor Protocol Number: RD-5103-007-06 Start Date*: 2008-02-21
    Sponsor Name:Derby Hospitals NHS Foundation Trust
    Full Title: An Observational and Exploratory Study to determine the effect of anti TNF Biologic Treatment in Rheumatoid Cachexia
    Medical condition: Cachexia in patients with Rheumatoid arthritis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-001481-32 Sponsor Protocol Number: Effetto anti-infiammatorio insulin Start Date*: 2006-09-21
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: Evaluation of the anti-inflammatory effect of continous insulin infusion in non-diabetic patients undergoing cardia surgery
    Medical condition: Patients candidate to cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 Cardiac disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005653-22 Sponsor Protocol Number: NL13PAR Start Date*: 2014-08-25
    Sponsor Name:Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital [...]
    1. Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital
    2. Takeda Nederland B.V.
    Full Title: TachoSil patch application as replacement of closed suction wound drainage by parotid gland surgery; a prospective study.
    Medical condition: The surgical procedure of parotidectomy whereby a protid tumor is removed. During this procedure the wound surface will be covered by the surgical sealing patch TachoSil instead of the use of a c...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004512-11 Sponsor Protocol Number: FJD-VITDAMI-14-01 Start Date*: 2015-08-06
    Sponsor Name:INSTITUTO DE INVESTIGACION SANITARIA FJD
    Full Title: Multicenter, randomized, double-blind, placebo-controlled study to evaluate the effect of vitamin D on ventricular remodeling in patients with acute myocardial infarction: Test VITDAMI (Vitamin D i...
    Medical condition: Acute myocardial infarction with ST segment elevation anterior
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005310-35 Sponsor Protocol Number: AD-03-013 Start Date*: 2014-08-13
    Sponsor Name:Fundación para la Investigación en Enfermedades del Aparato Digestivo
    Full Title: A phase IV double-blind, randomized, placebo-controlled, multi-center study with pancreatic enzyme replacement therapy (PERT) in subjects suffering from pancreatic exocrine insufficiency (PEI) afte...
    Medical condition: Patients 2 weeks after discharge from the hospital after an attack of acute necrotizing pancreatitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002427-32 Sponsor Protocol Number: TCA-01-III Start Date*: 2008-07-16
    Sponsor Name:UNIVERSITA' DEGLI STUDI DI FERRARA
    Full Title: Ajuste del tratamiento con tirofibán en pacientes que presentan resistencia a la aspirina o al clopidogrel: 3T/2R Tailoring Treatment with Tirofiban in patients showing Resistance to aspirin and/o...
    Medical condition: Pacientes con enfermedad coronaria que van a someterse a una intervención coronaria percutánea. Patients with coronary disease undergoing percutaneous coronary intervention
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011099 Coronary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001428-38 Sponsor Protocol Number: RRK2939 Start Date*: 2006-09-18
    Sponsor Name:University Hospitals Birmingham NHS Foundation Trust
    Full Title: Remission Induction in Very Early Rheumatoid Arthritis (RIVERA): a comparison of etanercept plus methotrexate plus steroid with standard therapy
    Medical condition: Patients with early inflamatory arthritis (duration of symptoms of < 12 weeks) who are at very high risk of the development of rheumatoid arthritis (seropositivity for Rheumatoid factor and anti-C...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004468-23 Sponsor Protocol Number: version3.0 Start Date*: 2020-02-10
    Sponsor Name:St George's, University of London
    Full Title: Comparison of abatacept with tumor necrosis factor inhibitors in the treatment of rheumatoid arthritis pain: A phase IV trial
    Medical condition: Rheumatoid arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-004527-32 Sponsor Protocol Number: SITADS Start Date*: 2016-11-22
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Kings College Hospital NHS Foundation Trust
    Full Title: Pilot randomised controlled trial of SITAgliptin for Depressive Symptoms in type 2 diabetes
    Medical condition: Depression in type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10012378 Depression PT
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-003978-10 Sponsor Protocol Number: INT/ISS 1 Start Date*: 2006-10-31
    Sponsor Name:ISTITUTO SUPERIORE DI SANITA'
    Full Title: Pilot Study with fixed dose of Cisplatinum in combination with esomeprazole (dose-ranging) as salvage treatment in patients with pre-treated advanced/methastatic melanoma
    Medical condition: Patient with metastatic melanoma (stage IV)
    Disease: Version SOC Term Classification Code Term Level
    6.1 10025671 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017448-15 Sponsor Protocol Number: GAIN Start Date*: 2009-12-15
    Sponsor Name:ISTITUTO NEUROLOGICO MEDITERRANEO NEUROMED
    Full Title: A multicenter, open label, hystorical Group controlled study by evaluate the effectivness and sAfety in the use of INfliximab (Tumor necrosis factor - alfa antibody) in preventing or reducing cereb...
    Medical condition: patient with cerebral hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    9.1 10047065 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-023006-12 Sponsor Protocol Number: 2010-362 Start Date*: 2011-01-14
    Sponsor Name:Professor Krzysztof Tadeusz Drzewiecki
    Full Title: Lipofilling with MSC enriched fat, a permanent autologous filler?
    Medical condition: Patients who have a need of reconstruction after surgery, eg. after mastectomy. The purpose of this clinical trial, is to make a reproducible and safe method for fat transplantation, that can be us...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10037773 Radical mastectomy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-002625-35 Sponsor Protocol Number: PERIOC_CTP001 Start Date*: 2015-01-26
    Sponsor Name:PerioC Ltd
    Full Title: The effect of locally delivered ciclosporin as an adjunct to healing after treatment of periodontal pockets
    Medical condition: Moderate to severe chronic periodontitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003594-95 Sponsor Protocol Number: MTXSB2018 Start Date*: 2019-04-30
    Sponsor Name:Amsterdam UMC location AMC
    Full Title: Methotrexate to suppress immunogenicity to anti-tumor necrosis factor therapy in IBD patients with loss of response
    Medical condition: Inflammatory bowel disease: Crohn's disease and Ulcerative colitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10011401 Crohn's disease PT
    20.1 10017947 - Gastrointestinal disorders 10045365 Ulcerative colitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004191-13 Sponsor Protocol Number: AVT-01/2/AST/04 Start Date*: 2007-01-23
    Sponsor Name:Avontec GmbH
    Full Title: Efficacy and safety of AVT-01 10 mg single dose in patients with mild asthma challenged with inhaled tumor necrosis factor alpha – A double-blind, randomized, placebo-controlled clinical study
    Medical condition: Male outpatients aged 18 - 65 with moderate persistent atopic asthma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003638 Atopic asthma LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022248-19 Sponsor Protocol Number: 114825 Start Date*: 2011-01-25
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: An open, phase II long term extension study to evaluate the immune responses to and safety of GSK Biologicals’ candidate herpes zoster vaccine, (gE/AS01B), at Months 48, 60 and 72 post-vaccination ...
    Medical condition: Evaluation of persistence of immune responses following immunisation of healthy elderly subjects (60-69 and ≥70 years) against Herpes Zoster (HZ)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019974 Herpes zoster LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) NL (Completed) CZ (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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