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Clinical trials for General anesthesia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    368 result(s) found for: General anesthesia. Displaying page 8 of 19.
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    EudraCT Number: 2021-003703-18 Sponsor Protocol Number: 2021/04 Start Date*: 2021-09-14
    Sponsor Name:CMC Ambroise Paré
    Full Title: Opioid free anesthesia in total hip arthroplasty. A randomized, controlled and triple-blind clinical trial.
    Medical condition: Total hip arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042613 Surgical and medical procedures SOC
    20.0 10042613 - Surgical and medical procedures 10043413 Therapeutic procedures and supportive care NEC HLGT
    20.0 10042613 - Surgical and medical procedures 10002185 Analgesia supportive care HLT
    21.1 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-000968-25 Sponsor Protocol Number: CHL1/02-2006/M; INN60M2006 Start Date*: 2007-07-16
    Sponsor Name:SINTETICA ITALIA S.R.L.
    Full Title: Prospective, blind observer, randomised clinical study to investigate and compare the efficacy of intrathecal plain solutions containing Chloroprocaine 1% (50 mg) versus Bupivacaine 0.5% (10 mg)
    Medical condition: patients undergoing elective short-duration (< 40 min) in low abdominal (gynaecology and urology disciplines) or lower limbs (no more than 1/3 of cases) surgery under spinal anaesthesia.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041536 Spinal anaesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-001252-35 Sponsor Protocol Number: DANA-2018-1. Start Date*: 2018-09-06
    Sponsor Name:Kirsten Møller
    Full Title: Neuroplasticity induced by general anaesthesia
    Medical condition: This trial investigates the effects of general anaesthesia on the helathy human brain. Thus, only healthy, young adults with no medical conditions will participate as volunteers in this study.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-000709-18 Sponsor Protocol Number: T2017-7 Start Date*: 2018-07-02
    Sponsor Name:Bernhoven
    Full Title: The effect of erector spinae block on postoperative pain and opioid use in patients undergoing breast cancer surgery with sentinel node dissection
    Medical condition: Patients undergoing unilateral (modified) mastectomy with sentinel node dissection for breast cancer
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004770-16 Sponsor Protocol Number: PNL_protocol_v01 Start Date*: 2016-01-04
    Sponsor Name:Jens Børglum
    Full Title: Ultrasoundguided Transmuscular Quadratus Lumborum(TQL) block for percutaneous nephrolithotomy (PNL) - a randomized controlled trial
    Medical condition: The postoperative pain after percutaneous nephrolithotomy(PNL) operation. Our one year retrospective study of patients treated with PNL, revealed that, 71% of all patients undergoing PNL operation...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004865 10038286 Regional nerve block LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-001770-15 Sponsor Protocol Number: 1418 Start Date*: 2020-01-24
    Sponsor Name:Complejo Asistencial Universitario de León
    Full Title: Analysis of the effectiveness of Non-painful Endovenous Management (MENA) in the administration of Propofol
    Medical condition: Propofol is used as an intravenous agent for induction and anesthetic maintenance. However, without any intervention before your administration, as is usually administered, the incidence of local p...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001777-86 Sponsor Protocol Number: 91710346.1.2 Start Date*: 2012-10-23
    Sponsor Name:
    Full Title: Pilot study for classification of attempted movement from the electroencephalogram in healthy participants with a temporary paralysis of one arm induced by local administration of rocuronium
    Medical condition: Intraoperative awareness during general anesthesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001592-20 Sponsor Protocol Number: 91710346.2.1 Start Date*: 2013-07-25
    Sponsor Name:
    Full Title: Pilot study for studying the influence of low-dose propofol on the classification of movements from the electroencephalogram in healthy participants
    Medical condition: Intraoperative awareness during general anesthesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004353-80 Sponsor Protocol Number: 179/2020 Start Date*: 2021-01-04
    Sponsor Name:
    Full Title: Laparoscopically inserted transversus abdominis plane block versus local wound anesthesia in laparoscopic peritoneal endometriosis surgery: a prospective randomized controlled double-blinded LTAP-t...
    Medical condition: The study subjects are patients with endometriosis needing surgical treatment.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2015-003956-32 Sponsor Protocol Number: POSTPAL Start Date*: 2016-03-15
    Sponsor Name:Umeå University
    Full Title: Effects of postoperative palonosetron in ambulatory patients identified with high risk for postdischarge nausea and vomiting (PDNV) – a randomized controlled trial with comparison to placebo.
    Medical condition: Nausea and vomiting in the home (after discharge) after day-case surgery under general anesthesia-
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004856 10028817 Nausea and vomiting symptoms HLT
    18.1 100000004863 10036285 Postoperative nausea LLT
    18.1 100000004865 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    18.1 100000004865 10054182 Perioperative nausea and vomiting prophylaxis LLT
    18.1 100000004863 10028818 Nausea postoperative LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005574-38 Sponsor Protocol Number: IJB-SUR-DESIGN-2015 Start Date*: 2016-03-17
    Sponsor Name:Institut Jules Bordet
    Full Title: The DESIGN trial A randomised, Double-blind, placEbo-controlled Study to assess the effectIveness of pectoral nerves block (Pecs) after breast surGery on Piritramide coNsumption.
    Medical condition: Locoregional analgesia in breast surgery (either conservative or non-conservative breast surgery associated with axillary dissection).
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10054799 Perioperative analgesia PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-002175-42 Sponsor Protocol Number: GernerDex001 Start Date*: 2011-10-12
    Sponsor Name:Paracelsus Medizinische Universität - Universitätsklinik für Anästhesie
    Full Title: The effect and safety of dexmedetomidine as an additive to ropivacaine for interscalene brachial plexus blocks for shoulder surgery
    Medical condition: The goal of the present study is to investigate the safety and efficiacy of dexmedetomidine added to ropivacaine for interscalene brachial plexus nerve block for shoulder surgery in humans. Provi...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-000556-11 Sponsor Protocol Number: RAPID_01 Start Date*: 2022-04-26
    Sponsor Name:Medical University of Vienna, Department of Anesthesia, Intensive Care Medicine and Pain Medicine
    Full Title: The effect of desflurane versus Sevoflurane on postoperative recovery in patients undergoing minor- to moderate-risk noncardiac surgery - a prospective double-blinded randomized clinical trial
    Medical condition: The evaluation of recovery times between desflurane and sevoflurane general anesthesia in patients ≥ 65 years of age undergoing minor- to moderate-risk noncardiac surgery
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-002947-23 Sponsor Protocol Number: DP10027 Start Date*: 2023-04-14
    Sponsor Name:Acacia Pharma Ltd
    Full Title: Randomized, double-blind, Phase 2/3 study of IV amisulpride as prevention of post-operative nausea and vomiting in pediatric patients
    Medical condition: post-operative nausea and vomiting in pediatric patients
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    Population Age: Newborns, Infants and toddlers, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-002306-21 Sponsor Protocol Number: P2014/PE2 Start Date*: Information not available in EudraCT
    Sponsor Name:Hôpital Universitaire Des Enfants Reine Fabiola
    Full Title: Monocentric, prospective randomized controlled clinical trial assessing the effect on the lower limb spinal motoneuron excitability, the efficacy in term of morphinic sparing and safety of of earl...
    Medical condition: Peri and post operative pain management
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-003909-26 Sponsor Protocol Number: BOP-TCI-001 Start Date*: 2014-02-04
    Sponsor Name:UMCG
    Full Title: Bayesian optimized Propofol Target-Controlled Infusion
    Medical condition: Patients requiring general anaesthesia for surgery using propofol and requiring an arterial line for invasive blood pressure monitoring as part of their clinical care.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004555-79 Sponsor Protocol Number: 16-115 Start Date*: 2017-08-08
    Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty
    Full Title: Impact of preoperative midazolam on outcome of elderly patients: a multicenter randomised controlled trial
    Medical condition: Under investigation are elderly patients (≥65 years of age) undergoing each kind of surgery with planned general or combined regional and general anaesthesia. Primary, we will investigate the posto...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-003178-17 Sponsor Protocol Number: 0869-148 Start Date*: 2009-01-19
    Sponsor Name:Merck & Co., Inc.
    Full Title: Estudio multicéntrico de 2 partes para evaluar la farmacocinética, la seguridad y la tolerabilidad del aprepitant en pacientes pediátricos sometidos a una intervención quirúrgica. A Multicenter, 2-...
    Medical condition: Prevención de nauseas y vómitos postoperatorios en pacientes pediátricos. Prevention of Postoperative nausea and vomiting in pediatric patients.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) FI (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-005384-31 Sponsor Protocol Number: RSIv80 Start Date*: 2021-03-19
    Sponsor Name:Rigshospitalet
    Full Title: A single blinded multicenter randomized study comparing intubating conditions during rapid sequence induction with either suxamethonium 1.0 mg/kg or rocuronium 1.0 mg/kg in elderly patients (≥ 80 y...
    Medical condition: The aim of this study is to determine the proportion of excellent tracheal intubation conditions at 60 seconds after administration of either rocuronium 1.0 mg/kg or suxamethonium 1 mg/kg in patien...
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004865 10051079 Orthopedic procedure LLT
    20.0 100000004856 10000082 Abdominal pain generalised LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002035-15 Sponsor Protocol Number: 0 Start Date*: 2016-05-20
    Sponsor Name:Helsinki University Central Hospital
    Full Title: Outcome after total knee arthroplasty under general or spinal anesthesia, a randomized study
    Medical condition: Patients undego total knee arthroplasty operation in general or spinal anaesthesia because of osteoarthritis, rheumatoid arthritis or other degenerative condition of the knee
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10031174 Osteoarthrosis LLT
    19.0 100000004859 10031158 Osteo arthritis knees LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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