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Clinical trials for Side effects

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    2,084 result(s) found for: Side effects. Displaying page 8 of 105.
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    EudraCT Number: 2013-000630-35 Sponsor Protocol Number: Start Date*: 2013-10-07
    Sponsor Name:Alder Hey Children's NHS Foundation Trust
    Full Title: Pilot study on use of Sulphur hexafluoride Microbubbles (SonoVue®) as a Magnetic Resonance Imaging contrast agent in the imaging of brain tumours.
    Medical condition: Patients undergoing pre-operative/follow up MRI investigation for a known enhancing brain tumour
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-002996-27 Sponsor Protocol Number: 13CC34 Start Date*: 2015-02-02
    Sponsor Name:Great Ormond Street Hospital For Children NHS Foundation Trust
    Full Title: Optimising effectiveness and minimising toxicity of intravenous salbutamol in children with acute asthma
    Medical condition: The mainstay of asthma treatment worldwide are β2-agonists and steroids. Current management of childhood acute asthma is based on British Thoracic Society guidelines, which recommend IVS as second ...
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-004860-31 Sponsor Protocol Number: 2.2.20110919 Start Date*: 2011-10-27
    Sponsor Name:Medical University of Vienna
    Full Title: Multimodal Assessment of Neurobiological Markers for Psychiatric Disorders
    Medical condition: Major Depressive Disorder Anxiety Disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-001151-40 Sponsor Protocol Number: CTU148N Start Date*: 2019-07-09
    Sponsor Name:RIEMSER Pharma GmbH
    Full Title: Phase II pilot study: To determine an effective and tolerable dose of Hylase® "Dessau" (bovine hyaluronidase) in the treatment of hyaluronic acid filler overshoots by injection into defined areas o...
    Medical condition: In this study, healthy subjects get an artificial over-injection with Hyaluron acid filler on the back of the hands. To demonstrate the effectiveness of hylase® "Dessau" as an antidote for hyaluro...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004872-76 Sponsor Protocol Number: RECUT-Trial Start Date*: 2020-05-07
    Sponsor Name:Medizinische Universtitätsklinik, Kantonsspital Baselland
    Full Title: Reduction of corticosteroid use in outpatient treatment of exacerbated COPD – a randomized, double-blind, non-inferiority study (The “RECUT”-Trial)
    Medical condition: acute exacerbation of COPD; acute exacerbation (defined solely by clinical parameters according to the Anthonisen criteria, meaning ≥2 of the following: change of baseline dyspnea, change of cough,...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10010953 COPD exacerbation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-005116-64 Sponsor Protocol Number: 16092021 Start Date*: 2021-12-13
    Sponsor Name:Aarhus University Hospital, Department of Anesthesiology
    Full Title: Low-dose ketamine as an adjunct to morphine for acute pain in the ED: a randomized, double-blinded, superiority trial
    Medical condition: Acute pain in the Emergency Department
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-001550-42 Sponsor Protocol Number: 1.8_20190705 Start Date*: 2014-06-17
    Sponsor Name:Medizinische Universität Wien
    Full Title: Patient stratification and treatment response prediction in neuropharmacotherapy using PET/MR – Predicting drug efficacy using hybrid PET/MR imaging with pharmacological challenge and multirecepto...
    Medical condition: Major depressive disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-006646-12 Sponsor Protocol Number: POMAlternative Start Date*: 2024-04-25
    Sponsor Name:Amsterdam UMC
    Full Title: Alternative dosing scheme of pomalidomide 4 mg every other day versus pomalidomide 2 mg and 4 mg every day: reduction in costs, same efficacy? A PKPD bioequivalence pilot study.
    Medical condition: Multiple myeloma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004261-14 Sponsor Protocol Number: 1703001 Start Date*: 2019-02-12
    Sponsor Name:Vestre Viken Trust
    Full Title: MUscle Side-Effects of atorvastatin in coronary patients (MUSE)
    Medical condition: Coronary heart disease patients With perceived statin Associated muscle symptoms or statin discontinuaton due to muscle symptoms
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000988-68 Sponsor Protocol Number: O2021-1 Start Date*: 2021-03-31
    Sponsor Name: Region Stockholm
    Full Title: Immune response after covid-19 vaccination in patients with renal failure stadium 4 or 5 .
    Medical condition: Renal failure stage 4 and 5.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2021-004049-19 Sponsor Protocol Number: NL77938.018.23 Start Date*: 2023-10-13
    Sponsor Name:Amsterdam UMC
    Full Title: Sodium oxybate as a potential new treatment for catatonia in patients with depression, bipolar disorder or a psychotic disorder, a randomized controlled trial. The Laborit study.
    Medical condition: Catatonia in patients with depression, bipolar disorder or a psychotic disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-000964-27 Sponsor Protocol Number: WP2018 Start Date*: 2018-05-09
    Sponsor Name:Karolinska Institutet
    Full Title: Medical termination of pregnancy from day 85 to day 153 of gestation: A randomized comparison between administration of the initial dose of misoprostol at home or in the clinic
    Medical condition: Unwanted pregnancy
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-000408-36 Sponsor Protocol Number: 08440012010002 Start Date*: 2022-10-25
    Sponsor Name:ZonMw
    Full Title: OMAMA-study – prevention of opioid-induced constipation in patients with advanced cancer
    Medical condition: Opioid-induced constipation in patients with advanced cancer, starting with opioids for pain
    Disease: Version SOC Term Classification Code Term Level
    24.0 10017947 - Gastrointestinal disorders 10071128 Opioid induced constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-001909-25 Sponsor Protocol Number: Start Date*: Information not available in EudraCT
    Sponsor Name:
    Full Title: Effekter av behandling med atomoxetine ved komorbid ADHD hos pasienter med Pervasive Developmental Disorders (Effects of treatment with atomoxetine in children with Pervasive Developmental Disorder...
    Medical condition: Open treatment with atomoxetine for 10 weeks: •Week 1: 0,5 mg/kg/day in 1 or 2 doses. •Week 2 – 6: 1,2 mg/kg/day i 1 or 2 doses. •Week 6 – 8: Significant improvements: Continue on 1,2 mg/kg/day in ...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000460-90 Sponsor Protocol Number: AGO/2006/002 Start Date*: 2006-03-09
    Sponsor Name:University Hospital Ghent
    Full Title: Echocardiographic study of the haemodynamic effects of remifentanil with and without glycopyrrolate in healthy children
    Medical condition: ASA I and II children
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002479-33 Sponsor Protocol Number: R2377 Start Date*: 2020-03-02
    Sponsor Name:Hull University Teaching Hospitals NHS Trust
    Full Title: A parallel group, double-blind, randomised, placebo-controlled trial comparing the effectiveness and cost effectiveness of low dose oral modified release morphine versus placebo on patient-reported...
    Medical condition: Chronic breathlessness due to cardiac, respiratory disease or cancer.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007554 Cardiac failure PT
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10009026 Chronic obstructive airways disease LLT
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10022611 Interstitial lung disease PT
    21.0 100000004864 10048683 Advanced cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-003542-32 Sponsor Protocol Number: SCOPE Start Date*: 2020-02-28
    Sponsor Name:Dr. José Manuel Porcel Pérez
    Full Title: Randomised clinical trial: saline washouts versus standard treatment in complicated parapneumonic pleural effusion or empyema. SCOPE study.
    Medical condition: Treatment of complicated parapneumatic pleural effusion or empyema
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002910-37 Sponsor Protocol Number: TEA Start Date*: 2019-10-07
    Sponsor Name:Erasmus MC
    Full Title: Study on the pharmacokinetic interaction between green tea and tamoxifen in patients with breast cancer. “the TEA study”
    Medical condition: Breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005060-24 Sponsor Protocol Number: Chirocain 2010 Start Date*: 2005-12-08
    Sponsor Name:Klinikum Leverkusen gGmbH
    Full Title: Comparison of Levobupivacaine and Ropivacaine for epidural application in obstetric gynaecology
    Medical condition: Comparison of Levobupivacaine and Ropivacaine for epidural application in obstetric gynaecology
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-006162-33 Sponsor Protocol Number: ML 19835 Start Date*: 2006-07-03
    Sponsor Name:ROCHE
    Full Title: Relationships between pharmacokinetic and pharmacodynamic strategies for assessment of the risks for acute rejection and side effects of mofetil mycophenolate
    Medical condition: Kidney transplantation
    Disease: Version SOC Term Classification Code Term Level
    6.1 10023439 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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