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Clinical trials for Type 2 diabetes

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    2,112 result(s) found for: Type 2 diabetes. Displaying page 9 of 106.
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    EudraCT Number: 2008-005263-34 Sponsor Protocol Number: MMB003 Start Date*: 2009-01-14
    Sponsor Name:The Mater Foundation/HRB Grant
    Full Title: The effect of insulin therapy on beta-cell survival in patients with Maturity Onset Diabetes of the Young ( MODY) 3. A 2 year, single-centre, open-label, randomised, parallel-group trial comparing...
    Medical condition: The effect of insulin therapy on beta-cell survival in patients with Maturity Onset Diabetes of the Young ( MODY ) 3.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012613 Diabetes mellitus non-insulin-dependent PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-005136-41 Sponsor Protocol Number: FIM-DAPA-2018-01 Start Date*: 2018-12-12
    Sponsor Name:Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina Y Salud (FIMABIS)
    Full Title: SGLT-2 Inhibition and Cardiovascular Disease. Metabolomics Study of Potential Factors Involved in Cardioprotection
    Medical condition: Type 2 Diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011399-31 Sponsor Protocol Number: NN1250-3718 Start Date*: 2009-12-21
    Sponsor Name:Novo Nordisk A/S
    Full Title: BEGIN™: EASY PM A trial comparing the efficacy and safety of NN1250 and insulin glargine in subjects with type 2 diabetes
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.0 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) HU (Completed) FR (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2004-002159-16 Sponsor Protocol Number: 0431-024 Start Date*: 2004-11-03
    Sponsor Name:Suomen MSD Oy
    Full Title: A Multicenter, Double-Blind, Randomized Study to Evaluate the Safety and Efficacy of the Addition of MK-0431 Compared With Sulfonylurea Therapy in Patients With Type 2 Diabetes With Inadequate Glyc...
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    7.0 10045242 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SE (Completed) DK (Completed) AT (Completed) LT (Completed) HU (Completed) CZ (Completed) GB (Completed) IT (Completed) DE (Completed) BE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-018318-62 Sponsor Protocol Number: 0431-229 Start Date*: 2010-06-01
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Phase III, Randomized, Clinical Trial to Evaluate the Safety and Efficacy of the Addition of Sitagliptin in Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on a Sulfon...
    Medical condition: Diabetes Mellitus type 2
    Disease: Version SOC Term Classification Code Term Level
    12.1 10067585 Type 2 diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-006092-21 Sponsor Protocol Number: NN2211-1797 Start Date*: 2007-05-14
    Sponsor Name:Novo Nordisk a/s
    Full Title: Effect on glycaemic control of liraglutide or exenatide added to metformin, sulphonylurea or a combination of both in subjects with type 2 diabetes A 26-week randomised, open-label, active compara...
    Medical condition: type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) IE (Completed) FI (Completed) DE (Completed) ES (Completed) DK (Completed) SI (Completed) FR (Completed) PL (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-000886-35 Sponsor Protocol Number: TAK-875_203 Start Date*: 2013-12-04
    Sponsor Name:Takeda Development Centre Europe Ltd.
    Full Title: A Phase 2 Randomized, Placebo-Controlled, Double-Blind Parallel-Group, Multicenter Study to Evaluate the Glycemic Effects and Safety of Fasiglifam 25 mg Twice Daily and 50 mg Once Daily on Glycemic...
    Medical condition: Type 2 diabetes mellitus (T2DM)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10063624 Type II diabetes mellitus inadequate control LLT
    14.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    14.1 10027433 - Metabolism and nutrition disorders 10029505 Non-insulin-dependent diabetes mellitus LLT
    14.1 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    14.1 10027433 - Metabolism and nutrition disorders 10012613 Diabetes mellitus non-insulin-dependent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-005979-97 Sponsor Protocol Number: 0816202 Start Date*: 2009-01-27
    Sponsor Name:CHU de Toulouse
    Full Title: EFFICACITE DU TRAITEMENT PAR POMPE A INSULINE EXTERNE CHEZ LE DIABETIQUE DE TYPE 2 : ETUDE RANDOMISEE EN PARALLELE SUR 1 AN VERSUS MULTI-INJECTIONS
    Medical condition: diabète de type II
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023433-35 Sponsor Protocol Number: 2010.639 Start Date*: 2011-06-01
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Implication des radicaux libres produits par la xanthine oxydase dans les altérations mitochondriales du muscle squelettique de patients diabétiques
    Medical condition: diabète type 2
    Disease: Version SOC Term Classification Code Term Level
    12.1 10067585 Type 2 diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003666-85 Sponsor Protocol Number: 11418 Start Date*: 2015-12-03
    Sponsor Name:Oxford University Hospitals NHS Trust
    Full Title: Investigation of appropriate timing of additional insulin dosing for fat and protein in children with type 1 diabetes using multiple daily injections
    Medical condition: Type 1 diabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-004434-41 Sponsor Protocol Number: 70917 Start Date*: 2020-04-16
    Sponsor Name:Flemming Pociot
    Full Title: Fenofibrate as an Early Treatment Option in Type 1 Diabetes: A randomized, double-blind, placebo-controlled, trial to evaluate antidiabetic effects of Fenofibrate in patient with newly onset type 1...
    Medical condition: Newly onset Type 1 Diabetes, with first insulin injection maximum six weeks prior inclusion in this trial
    Disease: Version SOC Term Classification Code Term Level
    21.1 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-007334-22 Sponsor Protocol Number: EFC10780 Start Date*: 2009-11-02
    Sponsor Name:Sanofi-Aventis Recherche & Développement
    Full Title: A randomized, double-blind, double-dummy, 2-arm parallel-group, multicenter 24-week study comparing the efficacy and safety of AVE0010 to sitagliptin as add-on to metformin in obese type 2 diabetic...
    Medical condition: Type II Diabetes
    Disease: Version SOC Term Classification Code Term Level
    11.1 10045242 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001692-19 Sponsor Protocol Number: NN304-1633 Start Date*: 2005-02-25
    Sponsor Name:Novo Nordisk AS
    Full Title: A single-centre, randomised, double-blind, cross-over trial comparing the within-subject variability of the pharmacokinetic profiles of insulin detemir and insulin glargine in children and adolesce...
    Medical condition: Type I Diabetes
    Disease: Version SOC Term Classification Code Term Level
    7.0 10012608 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2022-000743-68 Sponsor Protocol Number: LDX0122 Start Date*: 2022-12-13
    Sponsor Name:DOMPé FARMACEUTICI S.P.A.
    Full Title: A phase II randomized, placebo-controlled, double-blinded, 2-parallel arm, clinical trial evaluating Ladarixin 400 mg twice a day as adjunctive therapy to improve glycemic control in overweight ins...
    Medical condition: overweight insulin-resistant patients with type 1 diabetes
    Disease: Version SOC Term Classification Code Term Level
    21.1 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-003760-38 Sponsor Protocol Number: E7001-H001 Start Date*: 2005-10-14
    Sponsor Name:Sten Madsbad
    Full Title: Effect of three doses of nasal glp-1 versus placebo on postprandial hyperglycaemia in type 2 diabetes.
    Medical condition: postprandial hyperglycaemia in type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    10045242
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002104-32 Sponsor Protocol Number: NN1218-3888 Start Date*: 2014-11-14
    Sponsor Name:Novo Nordisk A/S
    Full Title: A trial investigating the pharmacokinetic properties of FIAsp in children, adolescents and adults with type 1 diabetes
    Medical condition: Diabetes Mellitus, Type 1
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004861 10045228 Type I diabetes mellitus LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-004993-68 Sponsor Protocol Number: 85256 Start Date*: 2022-04-28
    Sponsor Name:Steno Diabetes Center Copenhagen
    Full Title: The HYPO-AVOID STUDY: Low-dose Glucagon and Advanced Hybrid Closed-loop System for Prevention of Exercise-Induced Hypoglycaemia in People with Type 1 Diabetes
    Medical condition: Type 1 Diabetes
    Disease: Version SOC Term Classification Code Term Level
    21.1 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001392-37 Sponsor Protocol Number: 0431-053 Start Date*: 2006-07-21
    Sponsor Name:Merck Sharp & Dohme GesmbH
    Full Title: A Multicenter, Double-Blind, Randomized Study to Evaluate the Safety and Efficacy of the Addition of Sitagliptin to Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Me...
    Medical condition: type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    7.0 10045242 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-001634-28 Sponsor Protocol Number: CVMD-DU-087 Start Date*: 2008-11-11
    Sponsor Name:University of Dundee
    Full Title: Identification of genetic and functional biomarkers that predict PPAR-gamma-associated fluid retention and oedema
    Medical condition: Patients with Type 2 diabetes mellitus (T2DM) whoa re not receiving insulin treatment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012613 Diabetes mellitus non-insulin-dependent LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-000641-54 Sponsor Protocol Number: 1245.10 Start Date*: 2008-08-28
    Sponsor Name:Boehringer Ingelheim Finland Ky
    Full Title: A Phase II, randomized, parallel group safety, efficacy, and pharmacokinetics study of BI 10773 (1mg, 5mg, 10mg, 25mg, and 50mg) administered orally once daily over 12 weeks compared double blind t...
    Medical condition: Typr 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) FR (Completed) ES (Completed) DE (Completed) LV (Completed) AT (Completed) SK (Completed) CZ (Completed) HU (Completed) EE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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