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Clinical trials for 1

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44353   clinical trials with a EudraCT protocol, of which   7380   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    39,280 result(s) found for: 1. Displaying page 901 of 1,964.
    EudraCT Number: 2004-000766-12 Sponsor Protocol Number: SCO/BIA-2093-301 Start Date*: 2005-03-21
    Sponsor Name:BIAL Portela & Companhia, S.A.
    Full Title: Efficacy and safety of BIA 2-093 as adjunctive therapy for refractory partial seizures in a double-blind, randomised, placebo-controlled, parallel-group, multicentre clinical trial
    Medical condition: About 40% of the patients suffering from epilepsy are not satisfactorily controlled and 25% suffer from significant adverse events. This lack of seizure control means that combination therapy is of...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001019-23 Sponsor Protocol Number: 04-TH01-01 Start Date*: 2005-05-11
    Sponsor Name:BioInvent International AB
    Full Title: A double blind, phase I/II, randomized, single and repeat dose, dose escalation study of the antibody BI-201 directed against Tat, given IV, versus Placebo in asymptomatic HIV-1 patients.
    Medical condition: HIV-1 (asymptomatic patients)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001246-16 Sponsor Protocol Number: CCR104458 Start Date*: 2005-08-16
    Sponsor Name:GlaxoSmithKline Research and Development
    Full Title: A Phase III, randomized, double-blind, placebo-controlled, multicenter, parallel group study to compare the efficacy and safety of GW873140 400mg BID in combination with a ritonavir-containing opti...
    Medical condition: Treatment of HIV-1 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) IE (Completed) DK (Prematurely Ended) GB (Completed) AT (Completed) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-000489-37 Sponsor Protocol Number: SURF-04-01 Start Date*: 2005-08-26
    Sponsor Name:Nektar Therapeutics
    Full Title: An open label, randomized, controlled study to evaluate the safety and efficacy of aerosolized surfactant, Curosurf®, delivered via nasal continuous positive airway pressure pulmonary drug delivery...
    Medical condition: The medical condition for this application is the Respiratory Distress Syndrome (RDS). RDS, also known as hyaline membrane disease, is characterized by lung immaturity and surfactant deficiency a...
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002744-25 Sponsor Protocol Number: RK100.1 Start Date*: 2006-06-29
    Sponsor Name:Roskamp Institute
    Full Title: An open label evaluation of the safety and efficacy of nilvadipine in mild to moderate Alzheimer's Disease
    Medical condition: Alzheimer's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000619-85 Sponsor Protocol Number: 2937 Start Date*: 2005-05-25
    Sponsor Name:The University of Liverpool [...]
    1. The University of Liverpool
    2. The Royal Liverpool and Broadgreen University Hospitals NHS Trust
    Full Title: The relationship between genetic polymorphisms in the organic cation transporter genes and the pharmacokinetics and pharmacodynamics of metformin
    Medical condition: Type 2 diabetes mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001870-29 Sponsor Protocol Number: 205.324 Start Date*: 2005-08-29
    Sponsor Name:Hospital Clínic de Barcelona
    Full Title: EFECTOS DE UN ANTICOLINÉRGICO DE ACCIÓN PROLONGADA (BROMURO DE TIOTROPIO) SOBRE EL DESEQUILIBRIO DE LAS RELACIONES VENTILACIÓN-PERFUSIÓN (VA/Q) EN LA ENFERMEDAD PULMONAR OBSTRUCTIVA CRÓNICA ESTABLE
    Medical condition: enfermedad pulmonar obstructiva crónica
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001356-20 Sponsor Protocol Number: 0602001 Start Date*: 2006-06-05
    Sponsor Name:Reckitt Benckiser (UK) Limited
    Full Title: A preliminary single dose, three-way, double-blind, placebo-controlled crossover study of intravenous buprenorphine/naloxone in the treatment of neuropathic pain of diabetic neuropathy origin.
    Medical condition: Neuropathic pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-003775-13 Sponsor Protocol Number: testa-collo Start Date*: 2004-10-12
    Sponsor Name:OSPEDALE ONCOLOGICO DI BARI
    Full Title: A phase II study of Capecitabine in combination with Cisplatin in advanced head and neck Cancer
    Medical condition: Advanced or metastatic head and neck cancer
    Disease: Version SOC Term Classification Code Term Level
    10024530 HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000282-11 Sponsor Protocol Number: HADUEGRO 2006 Start Date*: 2006-08-17
    Sponsor Name:Universitätsklinikum Hamburg-Eppendorf
    Full Title: Clinical trial for the research into changes in renal function of adolescent and adult patients with Glycogen storage disease type Ia.
    Medical condition: Glycogen storage disease type Ia
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000051-10 Sponsor Protocol Number: A091200 Start Date*: 2008-05-19
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
    Full Title: 11C metomidate PET scanning for Conn's syndrome
    Medical condition: Primary hyperaldosteronism - Conn's syndrome and bilateral adrenal hyperplasia. Imaging of adrenal lesions using 11C-metomidate PET. Pre-suppression with dexamethasone and/or fludrocortisone to opt...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004371-19 Sponsor Protocol Number: ARC1779-004 Start Date*: 2007-11-20
    Sponsor Name:Archemix Corp.
    Full Title: A Phase 2 Pilot Study of the Safety, Pharmacokinetics, and Pharmacodynamics of ARC1779 Injection in Patients with von Willebrand Factor-Related Platelet Function Disorders
    Medical condition: von Willebrand Factor- related platelet function disorders : thrombotic thrombocytopenic purpura(TTP) in remission, acute TTP, and von Willebrand Disease Type- 2b (vWD-2b).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037563 Purpura thrombopenic thrombotic LLT
    9.1 10047715 Von Willebrand's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005747-42 Sponsor Protocol Number: 1255/08 Start Date*: 2009-02-03
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Efficacy of a medical product containing sorbitol, simethicone and citrate potassium, in comparison with domperidone in patients affected by disfunctional dyspepsia: randomized monocentric cross-ov...
    Medical condition: dysfunctional dyspepsia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064536 Functional dyspepsia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003887-21 Sponsor Protocol Number: 0802/SM Start Date*: 2010-01-21
    Sponsor Name:Univ.-Doz. Dr. Karl-Heinz Smolle
    Full Title: Klinische Studie zur Überprüfung des Einflusses einer intradialytischen Verabreichung von Vitamin E und Vitamin C auf biochemische Indikatoren für die antioxidative Kapazität sowie auf Entzündungsm...
    Medical condition: Akutes Nierenversagen und Sepsis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-005777-22 Sponsor Protocol Number: MRSA-01 Start Date*: 2009-04-07
    Sponsor Name:Dermal Laboratories
    Full Title: Control of MRSA skin and wound colonisation.
    Medical condition: MRSA-colonised community patients with "uncomplicated" venous leg ulcers scheduled to receive regular nursing care, for 12 to 15 weeks, will be considered for the study. NB: There is no intention t...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000163-26 Sponsor Protocol Number: HS-05-161 Start Date*: 2008-08-01
    Sponsor Name:Camurus AB
    Full Title: A randomised, two-period cross-over, multicentre, double-blind, single-dose, placebo-controlled study to assess the local analgesic effect of CAM2028 in head-and-neck cancer patients suffering from...
    Medical condition: Head-and-neck cancer patients suffering from radiation-indused oral mucositis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037763 Radiation mucositis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2008-005025-11 Sponsor Protocol Number: BAY43-9006/13162 Start Date*: 2009-05-06
    Sponsor Name:Bayer Healthcare AG, D-51368 Leverkusen, Germany
    Full Title: A Phase 2b, Double Blind, Randomized Study Evaluating the Efficacy and Safety of Sorafenib Compared With Placebo When Administered in Combination With Chemotherapy (Modified FOLFOX6) for the Treatm...
    Medical condition: The patient population includes patients with Stage IV metastatic colorectal cancer (mCRC), with Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1. Patients must have measurable ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000073-39 Sponsor Protocol Number: 248.524 Start Date*: 2007-05-29
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: A double-blind, double-dummy, placebo-controlled, randomized, three parallel groups study comparing the Efficacy, Safety and Tolerability of Pramipexole ER versus placebo and versus Pramipexole IR ...
    Medical condition: Male or female patients with idiopathic Parkinson’s disease (PD), diagnosed within 5 years, having Modified Hoehn and Yahr stage of 1 to 3.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061536 Parkinson's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed) CZ (Completed) HU (Completed) AT (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2009-016608-22 Sponsor Protocol Number: PHRCIR09-DrTOURNEUX Start Date*: 2010-01-27
    Sponsor Name:CHU AMIENS
    Full Title: Administration de Surfactant précoce : Evaluation chez le Nouveau-né ≥ 35 semaines d’aménorrhée présentant une détresse respiratoire
    Medical condition: Détresse respiratoire du nouveau-né entre 35 et 41 semaines d'aménorrhées
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006177-88 Sponsor Protocol Number: FARM65KNKY Start Date*: 2008-01-24
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: A randomized controlled trial of alteplase (rt-PA) vs standard treatment in acute ischemic hemispheric stroke in patients aged more than 80 years where thrombolysis is initiated within 3 hours afte...
    Medical condition: acute ischemic stroke
    Disease: Version SOC Term Classification Code Term Level
    9.1 10043647 Thrombotic stroke LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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