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Clinical trials for II

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    11,926 result(s) found for: II. Displaying page 96 of 597.
    EudraCT Number: 2015-002799-26 Sponsor Protocol Number: Start Date*: 2015-10-27
    Sponsor Name:Papworth Hospital NHS Foundation Trust
    Full Title: TRANSFORM-UK: A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension
    Medical condition: Pulmonary arterial hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-003728-36 Sponsor Protocol Number: 21012 Start Date*: 2004-12-10
    Sponsor Name:E.O.R.T.C. - EUROPEAN ORGANIZATION FOR RESEARCH AND TREATMENT OF CANCER
    Full Title: PHASE II CLINICAL TRIAL WITH CAELYX MONO-CHEMOTHERAPY IN PATIENTS WITH ADVANCED MYCOSIS FUNGOIDES STAGE IIb, IVa AND IVb WITH OR WITHOUT PREVIOUS CHEMOTHERAPY.
    Medical condition: ADVANCED STAGE CUTANEOUS T CELL LYMPHOMA.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-013103-63 Sponsor Protocol Number: 1884 Start Date*: 2011-12-14
    Sponsor Name:Asklepios Kliniken Hamburg GmbH
    Full Title: Pilot study investigating the effect of intra-coronary and intra-myocardial application of enriched CD133pos autologous bone marrow derived stem cells for improving left ventricular function in chr...
    Medical condition: Patients with chronic ischemic cardiomyopathy with an LVEF ≤45% and symptomatic heart failure NYHA ≥ II under optimal therapy and drug treatment according to the current ESC heart failure guidelines.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000924-42 Sponsor Protocol Number: LAPADO-Study Start Date*: 2007-06-06
    Sponsor Name:Sana Klinikum Lichtenberg
    Full Title: Phase I/II-Studie zur neoadjuvanten Chemotherapie mit nicht-pegyliertem liposomalem Doxorubicin, Paclitaxel und Lapatinib bei Patientinnen mit HER2-überexprimierenden, primärem Mammakarzinomen
    Medical condition: Im Rahmen der klinischen Studie soll eine Chemotherapie, die aus den Medikamenten nicht-pegyliertes liposomales Doxorubicin, Paclitaxel und Lapatinib besteht, verabreicht werden. Das Ziel dieser kl...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-000823-15 Sponsor Protocol Number: NEUPRODEX Start Date*: 2013-12-23
    Sponsor Name:Charité – Universitätsmedizin Berlin
    Full Title: Neuroprotection with Dexmedetomidine in patients undergoing elective cardiac or abdominal surgery
    Medical condition: The drug Dexmedetomidine will be investigated in patients (men and women) undergoing elective cardiac or abdominal surgery. The study medication will be administered perioperatively by intravenous ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001362-40 Sponsor Protocol Number: CSTI571BIT15 Start Date*: 2004-07-22
    Sponsor Name:NOVARTIS FARMA
    Full Title: PHASE II STUDY OF IMATINIB MESYLATE IN CHORDOMA
    Medical condition: Treatment of advanced or unresectable chordoma
    Disease: Version SOC Term Classification Code Term Level
    6.1 10008747 PT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-021410-34 Sponsor Protocol Number: EOC-2-Opht-2010 Start Date*: 2010-08-12
    Sponsor Name:Medical Centre Haaglanden
    Full Title: A double blind randomized study on the efficacy of cyclopentolate 1% and cyclopentolate 1% with tropicamide 1% in children
    Medical condition: Depth of cycloplegia; changes of astigmatism; recuperation from cycloplegia and mydriasis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10011719 Cycloplegia LLT
    12.1 10011719 Cycloplegia PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002117-30 Sponsor Protocol Number: 000010/BT Start Date*: 2016-02-16
    Sponsor Name:Bone Therapeutics S.A.
    Full Title: A Two-stage 6-month, Multicentre, Randomised, Double-blind, Controlled Study on the Safety and Efficacy of a Single Intra-articular Administration of JTA-004 in Patients with Symptomatic Knee Osteo...
    Medical condition: Symptomatic osteoarthritis of the knee with Kellgren-Lawrence grade II and III
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-001415-21 Sponsor Protocol Number: MRI-R-USPIO-05-2005 Start Date*: 2005-07-20
    Sponsor Name:Institut für Röntgendiagnostik der Technischen Universität München
    Full Title: Phase II Studie zur Evaluierung der SH U 555 C unterstützten Magnetresonanztomographie der arteriosklerotischen Karotisstenose bei Patienten vor Thrombendarteriektomie
    Medical condition: Arteriosklerotische Karotisstenose
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001754-92 Sponsor Protocol Number: AAE581C2201 Start Date*: 2005-02-14
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A phase II, 12-month, double-blind, placebo-controlled, dose-finding, multicenter study to evaluate the safety, tolerability, and disease modifying efficacy of daily oral AAE581 (10, 25 and 50 mg t...
    Medical condition: Osteoarthritis (OA) is a disease with a complex pathophysiology leading to the degeneration of articular cartilage and bone. It is characterized by pain, biochemical and enzymatic changes, cartilag...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004449-32 Sponsor Protocol Number: AR II 01-2005 Start Date*: 2006-01-12
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALI RIUNITI DI BERGAMO A.O. DI RILIEVO NAZIONALE
    Full Title: EFFECTIVENESS OF THE LEVOSIMENDAN IN THE THERAPY OF DIASTOLIC DYSFUNCTION OF CARDIAC SURGERY
    Medical condition: DIASTOLIC DYSFUNCTION OF CARDIAC SURGERY TREATMENT BEFORE SURGERY
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-007056-18 Sponsor Protocol Number: 3403 Start Date*: 2007-03-16
    Sponsor Name:The Newcastle upon tyne Hospitals NHS Trust
    Full Title: The Discoid Lupus Research Project
    Medical condition: Discoid lupus erythematosus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013072 Discoid lupus erythematosus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-007974-45 Sponsor Protocol Number: EKZ-AMC001 Start Date*: 2009-07-16
    Sponsor Name:AMC
    Full Title: Phase II trial of the combination of gemcitabine and 131I-MIBG therapy in paediatric patients with relapsed or progressive neuroblastoma
    Medical condition: relapsed or progressive neuroblastoma in pediatric patients of 1 to 18 years
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing) DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000233-18 Sponsor Protocol Number: AIO KRK 0205 Start Date*: 2008-04-09
    Sponsor Name:Universität zu Köln
    Full Title: Phase I/II Studie zum Einsatz von Capecitabin und Oxaliplatin (XELOX) in Kombination mit Bevacizumab und Imatinib in der Erstlinientherapie von Patienten mit fortgeschrittenem kolorektalem Karzinom
    Medical condition: fortgeschrittenes kolorektalen Karzinom mit inoperablen Metastasen
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010035 Colorectal cancer stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-016317-20 Sponsor Protocol Number: SCA_LITIO_12 Start Date*: 2009-10-26
    Sponsor Name:UNIVERSITA` DEGLI STUDI DI NAPOLI FEDERICO II
    Full Title: PILOT STUDY TO ASSESS SAFETY AND TOLERABILITY OF LITHIUM ON SPINOCEREBELLAR ATAXIA OF TYPE 2
    Medical condition: Spinocerebellar ataxia type 2
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031722 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007241-12 Sponsor Protocol Number: PH-L19SIPI131-07/07 Start Date*: 2008-10-06
    Sponsor Name:Philogen S.p.A.
    Full Title: A PHASE I/II DOSE FINDING AND EFFICACY STUDY OF THE TUMOUR TARGETING HUMAN 131I-L19SIP MONOCLONAL ANTIBODY IN PATIENTS WITH CANCER
    Medical condition: Cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007050 Cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-024018-71 Sponsor Protocol Number: 2010-024018-71 Start Date*: 2011-03-31
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: PREMEDICATION IN CHILDREN: CLONIDINE VERSUS MELATONIN
    Medical condition: HEALTHY CHILDREN UNDERGOING ELECTIVE MINOR SURGERY
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002689-30 Sponsor Protocol Number: MedOPP107 Start Date*: 2017-03-16
    Sponsor Name:Medica Scientia Innovation Research (MedSIR ARO)
    Full Title: Multicenter open-label, phase II trial, to evaluate the efficacy and safety of nal-IRI for progressing brain metastases in patients with HER2-negative breast cancer
    Medical condition: Progressing brain metastases in patients with HER2-negative breast cancer.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004864 10027475 Metastatic breast cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001261-33 Sponsor Protocol Number: Start Date*: 2019-11-05
    Sponsor Name:University College London
    Full Title: Randomised phase II/III study of Rituximab and Ibrutinib (RI) versus Dexamethasone, Rituximab and Cyclophosphamide (DRC) as initial therapy for Waldenström's macroglobulinaemia
    Medical condition: Waldenström's macroglobulinaemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-005506-40 Sponsor Protocol Number: CLDE225B2203 Start Date*: 2009-08-06
    Sponsor Name:Novartis Pharma
    Full Title: A double-blind, randomized, vehicle-controlled Proof of Concept (PoC) study, to evaluate the safety, local tolerability, pharmacokinetics and pharmacodynamics of multiple topical administrations of...
    Medical condition: Gorlin syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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