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Clinical trials for II

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    11,926 result(s) found for: II. Displaying page 97 of 597.
    EudraCT Number: 2019-002051-42 Sponsor Protocol Number: R119861 Start Date*: 2019-10-25
    Sponsor Name:University of Manchester
    Full Title: A phase I-II, study of autologous CD34+ haematopoietic stem cells transduced ex vivo with CD11b lentiviral vector encoding for human SGSH in patients with mucopolysaccharidosis type IIIA (MPS IIIA,...
    Medical condition: MPS IIIA, mucopolysaccharidosis type IIIA
    Disease: Version SOC Term Classification Code Term Level
    20.1 10010331 - Congenital, familial and genetic disorders 10028093 Mucopolysaccharidosis PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-006191-30 Sponsor Protocol Number: IDI-ONC-3-20080901 Start Date*: 2008-12-20
    Sponsor Name:ISTITUTO DERMOPATICO IMMACOLATA
    Full Title: Biweekly Bevacizumab and weekly Carboplatin and Paclitaxel as II line therapy in advanced Malignant Melanoma patients: a phase II study
    Medical condition: patients with histologically confirmed progressive metastastic melanoma progressed after first line chemotherapy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040785 SOC
    9.1 10027480 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017848-14 Sponsor Protocol Number: ML25189 Start Date*: 2010-03-16
    Sponsor Name:Roche Farma, S.A.
    Full Title: Estudio fase II de capecitabina- oxaliplatino-trastuzumab (XELOX-trastuzumab) como tratamiento perioperatorio de pacientes con adenocarcinoma gástrico o de la unión gastroesofágica, resecable (esta...
    Medical condition: Pacientes diagnosticados de adenocarcinoma gástrico o de la unión gastroesofágica, resecable (estadios II-IV).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-022579-68 Sponsor Protocol Number: COR-1/02 Start Date*: 2011-08-16
    Sponsor Name:Corimmun GmbH
    Full Title: COR-1, an anti-ß1 receptor antibody cyclopeptide in heart failure: a phase II, multicentre, randomised, double-blind and placebo-controlled study with parallel groups
    Medical condition: Heart Failure, Dilated Cardiomyopathy
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10056419 Dilated cardiomyopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-013075-21 Sponsor Protocol Number: V72P9E1 Start Date*: 2009-08-18
    Sponsor Name:Novartis Vaccines and Diagnostics Srl.
    Full Title: A Phase 2, Open-Label, Single-Center, Extension Study Evaluating Antibody Persistence compared to Naïve Children and Safety, Tolerability and Immunogenicity of a Booster Dose of Novartis rMenB±OMV ...
    Medical condition: The Novartis Meningococcal B recombinant vaccine is intended for prevention of meningitis and/or septicemia caused by Neisseria meningitidis serogroup B. The objective of the Novartis Meningococcal...
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-004029-87 Sponsor Protocol Number: KCL/PCT-CT2004-1 Start Date*: 2005-01-24
    Sponsor Name:Institute of Psychiatry
    Full Title: Pillot randomised controlled trial of antidepressant switching for treatmetn-refractory depression in primary care
    Medical condition: Depression
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012063-33 Sponsor Protocol Number: H 569 000-0908 Start Date*: 2009-08-10
    Sponsor Name:Almirall Hermal GmbH
    Full Title: Double-blind, randomized, multi-centre phase II study to evaluate the efficacy and safety of topically applied LAS41007 once daily and LAS41007 twice daily versus Solaraze® 3% gel twice daily in th...
    Medical condition: Patients aged 18 and older suffering from actinic keratoses. Patients to be considered have at least four and up to ten actinic keratoses of grade I to grade II in two treatment blocks of 25 cm2 ea...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000614 Actinic keratosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-006073-24 Sponsor Protocol Number: CCR2983 Start Date*: 2008-05-22
    Sponsor Name:Royal Marsden Hospital
    Full Title: CINATRA: Chromosomal Instability and Anti-Tubulin Response Assessment: A Phase II Study of Epothilone B in Metastatic Colon Carcinoma in patients with Microsatellite Instability or Chromosomal Inst...
    Medical condition: Metastatic or locally recurrent colorectal cancer in genetically unselected patients, followed by recruitment of patients selected for microsatellite positive tumours
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010035 Colorectal cancer stage IV LLT
    9.1 10010030 Colorectal cancer recurrent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000354-31 Sponsor Protocol Number: 69529029 Start Date*: 2007-03-30
    Sponsor Name:GISCAD
    Full Title: A randomized trial investigating the role of FOLFOX-4 regimen duration (3 versus 6 months) and bevacizumab as adjuvant therapy for patients with stage II/III colon cancer
    Medical condition: treatment of metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061045 Colon neoplasm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004466-33 Sponsor Protocol Number: DCC 04 AM 012 Start Date*: 2005-08-01
    Sponsor Name:Dr. Theiss Naturwaren GmbH
    Full Title: doubleblind (observer blind), placebo-controlled, clinical-experimental study phase II in order to examine the local compatibility of Dr. Theiss Ringelblumen Salbe N by the duhring-chamber-test and...
    Medical condition: healthy subjects with normal skin conditions
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002290-52 Sponsor Protocol Number: ATC C09CA07 Start Date*: 2007-12-20
    Sponsor Name:University Clinic Erlangen, Medical Clinic II
    Full Title: Telmisartan und systemische Inflammationsparameter bei Patienten mit arterieller Hypertonie und asymtomatischer Koronarer Herzkrankheit
    Medical condition: Rekrutiert werden Patienten mit arterieller Hypertonie und asymptomatischer KHK. Bei diesen Patienten soll untersucht werden, ob Telmisartan zusätzlich zu seinem bekannten antihypertensiven Effekt ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000714-74 Sponsor Protocol Number: 1.0 Start Date*: 2008-07-15
    Sponsor Name:Institution of Paediatric Anaesthesia and intensiv care, Astrid Lindgren Childrens Hospital, Karolin
    Full Title: Premedication in paediatric patients: Dose finding study of clonidine administrated as nasal aerosol.
    Medical condition: Premedication prior to anaesthesia
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000394-21 Sponsor Protocol Number: HDP 605 Start Date*: 2005-07-05
    Sponsor Name:Heidelberg Pharma
    Full Title: A Double-Blind Phase II Study of HDP 99.0006 in Patients with Actinic Keratosis
    Medical condition: Aktinic Keratosis Stage II and III.
    Disease: Version SOC Term Classification Code Term Level
    7.1 10000614 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015005-39 Sponsor Protocol Number: MW005 Start Date*: 2009-11-03
    Sponsor Name:Dr. Willmar Schwabe GmbH & Co. KG
    Full Title: Monocentric prospective randomized controlled open phase IV study to explorate the mechanismen of the synergetic effect of the Crateagus -Extract WS® 1442 in addition to endurance training related ...
    Medical condition: heart failure, stage NYHA II
    Disease: Version SOC Term Classification Code Term Level
    12.0 10019279 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-004910-16 Sponsor Protocol Number: P/2013/209 Start Date*: 2014-03-31
    Sponsor Name:Centre Hospitalier régional Universitaire de Besançon
    Full Title: Therapeutic multicentric phase II trial evaluating the efficacy of omalizumab (Xolair ®) in idiopathic refractory severe solar urticaria
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002213-19 Sponsor Protocol Number: ELICE-BD-O1 Start Date*: 2019-09-19
    Sponsor Name:University of British Columbia
    Full Title: A 6-Week Randomised, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy of Lurasidone Adjunctive Therapy in Improving Cognitive Functioning in Euthymic Bipolar Disorder Pa...
    Medical condition: Euthymic Bipolar disorder
    Disease: Version SOC Term Classification Code Term Level
    21.1 10037175 - Psychiatric disorders 10057667 Bipolar disorder PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-002109-24 Sponsor Protocol Number: 09122019 Start Date*: 2019-08-01
    Sponsor Name:Tampere University Hospital
    Full Title: Oral Disodiumpyrophosphate (Na2H2PPi) Absorption in Pseudoxanthoma Elasticum
    Medical condition: Pseudoxanthoma elasticum
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010738-23 Sponsor Protocol Number: MPN-SG01-09 Start Date*: 2009-11-12
    Sponsor Name:Universitätsklinikum Ulm
    Full Title: Multi-Center Phase II Study with Pomalidomide in Patients with Myeloproliferative Neoplasms in Fibrotic Stage
    Medical condition: This is a phase II, multi-center study of pomalidomide in adult patients with Primary myelofibrosis, Secondary myelofibrosis, and unclassifiable Myeloproliferative Neoplasms showing at least grade ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001528-69 Sponsor Protocol Number: EmergencyMedicineTrial001 Start Date*: 2016-10-07
    Sponsor Name:Royal College of Surgeons in Ireland
    Full Title: PENICILLIN FOR THE EMERGENCY DEPARTMENT-DIRECTED OUTPATIENT TREATMENT OF CELLULITIS (PEDOCELL) STUDY: A NON-INFERIORITY ADAPTIVE RANDOMISED CONTROLLED TRIAL.
    Medical condition: Skin Infection
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004614-32 Sponsor Protocol Number: IEO S262/505 Start Date*: 2006-01-20
    Sponsor Name:ISTITUTO EUROPEO DI ONCOLOGIA
    Full Title: Randomized phase II trial of Budesonide Turbuhaler 800 micrograms/twice daily versus placebo in high-risk population with undetermined lung nodules detected at screening low dose CT scan
    Medical condition: Intermediate biomarker modulation in lung carcinogenesis
    Disease: Version SOC Term Classification Code Term Level
    6.1 10049498 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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