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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 975 of 2,219.
    EudraCT Number: 2006-000775-15 Sponsor Protocol Number: TERBI 06/05 Start Date*: 2006-09-11
    Sponsor Name:PLIVA - ISTRAŽIVANJE I RAZVOJ d.o.o.
    Full Title: Double blind, comparative, randomized, placebo controlled, clinical study of therapeutic equivalence and tolerability of the topical preparation Terbinafine cream 1% (Pliva Croatia) with the medica...
    Medical condition: Uncomplicated Tinea pedis.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002744-28 Sponsor Protocol Number: IOM-510-2 Start Date*: 2006-09-12
    Sponsor Name:iOMEDICO
    Full Title: Effektivitätsoptimierte und toxizitätsreduzierte Therapie des metastasierten Kolorektalkarzinoms in der First-line Therapie
    Medical condition: metastastic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    8.1 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002925-29 Sponsor Protocol Number: 200605 Start Date*: 2005-09-20
    Sponsor Name:University Childrens Hospital
    Full Title: Irinotecan singele drug treatment for children with refractory or relapsed hepatoblastoma
    Medical condition: Refractory or recurrent hepatoblastoma
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000583-28 Sponsor Protocol Number: NIME – 04 – 14 Start Date*: 2005-11-03
    Sponsor Name:HELSINN HEALTHCARE SA
    Full Title: EFFICACY AND TOLERABILITY OF NIMESULIDE FOR THE TREATMENT OF MIGRAINE TTACKS: A RANDOMISED, MULTICOUNTRY, DOUBLE BLIND, PLACEBO CONTROLLED, CROSS-OVER TRIAL
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001067-64 Sponsor Protocol Number: BURKIMAB007/04 Start Date*: 2005-07-25
    Sponsor Name:PETHEMA Foundation
    Full Title: Multicentre study of optimization of therapy in mature B-cell acute lymphoblastic leukemia and Burkitt's lymphoma in adults (over 15 years)
    Medical condition: Adults B-ALL and Burkitt´s Lymphoma
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002880-19 Sponsor Protocol Number: lapaz2006 Start Date*: 2006-09-14
    Sponsor Name:Servicio de psiquiatria. Hospital Universitario La Paz
    Full Title: Comparación de dos estrategias de intervención para el tratamiento de los trastornos depresivos en pacientes oncológicos
    Medical condition: Major depressive Disorder, one episode or several episodes. ICD: 296.2x, 296.3x
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002060-26 Sponsor Protocol Number: 1401201 Start Date*: 2006-12-04
    Sponsor Name:Intendis GmbH
    Full Title: A double-blind, randomized, vehicle-controlled, 6-week exploratory multicenter pilot study of the efficacy and safety of Azelaic Acid (AzA) 15% gel in the topical treatment of mild to moderate seb...
    Medical condition: Patients with mild to moderate seborrheic dermatitis of the facial area and meeting the specific eligibility criteria
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012488 Dermatitis seborrheic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001430-40 Sponsor Protocol Number: 012-06 Start Date*: 2007-05-04
    Sponsor Name:University Hospital Department of Cardiology
    Full Title: Tiral of Invasive versus Medical therapy of Early coronary artery disease in Diabetes (TIME-DM)
    Medical condition: The prevalence of type II diabetes is increasing rapidly, contributing importantly to a new "epidemic" of coronary artery disease (CAD). Atherosclerosis accounts for 65-80% of all death among diabe...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004151-35 Sponsor Protocol Number: PK-1 Start Date*: Information not available in EudraCT
    Sponsor Name:Universität Heidelberg
    Full Title: Pharmacokinetics of oral cefuroxime-axetil compared to intravenous cefuroxime in term neonates and possible adjustment of the oral therapy
    Medical condition: 12 Patients (full term neonates with 7 to 28 days of age) with infections of the skin, the nails or the respiratory tract.
    Disease:
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001472-20 Sponsor Protocol Number: LEO19123-C21 Start Date*: 2006-08-15
    Sponsor Name:LEO Pharma A/S
    Full Title: LEO19123 Cream in the Treatment of Atopic Dermatitis A Phase II, proof of concept study, testing once daily use of two dose-combinations of LEO19123 cream (calcipotriol and LEO80122) in the treatm...
    Medical condition: Atopic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003639 Atopic dermatitis LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed) FI (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002273-41 Sponsor Protocol Number: OPHT-110106 Start Date*: 2006-06-12
    Sponsor Name:Medical University of Vienna; Clinical Pharmacology
    Full Title: Effect of antioxidants on ocular blood flow, endothelial function, and cytokine levels in LPS induced inflammatory model in humans.
    Medical condition: only healthy volunteers are involved
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2004-004314-16 Sponsor Protocol Number: 1 R01 NS45109-01A1 Start Date*: 2005-04-25
    Sponsor Name:NINDS
    Full Title: Ensayo multicéntrico de tratamiento de la hipotiroxinemia transitoria en los niños <= 1000 gr de peso al nacimiento o <= 28 semanas de gestación y seguimiento del desarrollo psicomotor hasta los 5 ...
    Medical condition: The aims of the study are to compare two dosing levels and the mode of administration of thyroid hormones or iodine supplementation in premature infants to achieve optimal plasma hormone targets. T...
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003666-42 Sponsor Protocol Number: CXUO320BES04 Start Date*: 2006-09-04
    Sponsor Name:Fundación Castellano-Leonesa de Cardiología (FUCALEC)
    Full Title: ENSAYO CLÍNICO DE FASE IV / III, DOBLE CIEGO, ALEATORIZADO, PROSPECTIVO, PARA EVALUAR LA EFICACIA DE FLUVASTATINA SOBRE LOS MARCADORES INFLAMATORIOS EN LA PROGRESIÓN HEMODINÁMICA DE LA ESTENOSIS AÓ...
    Medical condition: Aortic stenosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-007068-27 Sponsor Protocol Number: 0604603 Start Date*: 2007-03-23
    Sponsor Name:CHU Toulouse
    Full Title: Réduction de la reconsolidation du souvenir traumatique par le propranolol : un essai pilote.
    Medical condition: Troubles du Stress Post-Traumatique (TSPT)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036316 Post-traumatic stress disorder LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002185-19 Sponsor Protocol Number: C119 Start Date*: 2006-09-06
    Sponsor Name:NeurogesX Incorporated
    Full Title: A MULTICENTER RANDOMIZED, DOUBLE-BLIND, CONTROLLED STUDY OF NGX-4010 FOR THE TREATMENT OF PAINFUL HIV-ASSOCIATED NEUROPATHY
    Medical condition: Treatment of painful HIV-associated neuropathy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10054095 Neuropathic pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001468-21 Sponsor Protocol Number: KIIOIW001 Start Date*: 2006-08-24
    Sponsor Name:Karolinska Institutet
    Full Title: Sympthomatic and prophylactic treatment of drug induced oral dryness in elderly patients with high drug consumption.
    Medical condition: Oral dryness is a common problem with serious consquences, especially among elderly individuals. The most common reason for oral dryness is drug consumption. Research has shown that an individual w...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001680-33 Sponsor Protocol Number: MH-130 Start Date*: 2006-06-23
    Sponsor Name:BRACCO IMAGING
    Full Title: Phase IV, Double-blind, Multi-center, Randomized, Cross-over Study to Compare 0.10 mmol/kg of MultiHance R with 0.10 mmol/kg of Omniscan R in Magnetic Resonance Imaging MRI of the Brain
    Medical condition: patients sent to the sites with a request for assessment/diagnoses of certain/suspected brain neoplasms
    Disease: Version SOC Term Classification Code Term Level
    6.1 10029816 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004836-61 Sponsor Protocol Number: Dexmed-2006-PICU Start Date*: 2006-11-08
    Sponsor Name:Royal Hospital for Sick Children, Glasgow
    Full Title: Dexmedetomidine as a sedative in paediatric intensive care.
    Medical condition: Children who require sedation and analgesia whilst receiving ventilatory support in the paediatric intensive care unit.
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004768-32 Sponsor Protocol Number: A0081147 Start Date*: 2008-04-21
    Sponsor Name:Pfizer S.A.
    Full Title: “ESTUDIO DE SEGURIDAD Y EFICACIA A LARGO PLAZO DE PREGABALINA EN SUJETOS CON TRASTORNO DE ANSIEDAD GENERALIZADA” "LONG TERM SAFETY AND EFFICACY STUDY OF PREGABALIN IN SUBJECTS WITH GENERALIZED ANX...
    Medical condition: Trastorno de ansiedad generalizada (TAG)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018105 Generalized anxiety disorder LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) LT (Completed) FI (Completed) AT (Completed) CZ (Completed) SI (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2006-004366-14 Sponsor Protocol Number: MK-0364 012 Start Date*: 2006-11-13
    Sponsor Name:Merck Sharp & Dohme (Sweden) AB
    Full Title: Full title of the trial A Study to Assess the Efficacy and Tolerability of MK-0364 in Maintaining Weight Loss Induced by Diet in Obese Patients Followed by a 1-Year Extension
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    8.1 10029883 Obesity LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) DK (Prematurely Ended)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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