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Clinical trials for II

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    11,926 result(s) found for: II. Displaying page 98 of 597.
    EudraCT Number: 2004-002908-15 Sponsor Protocol Number: B9E-XM-O401 Start Date*: 2004-12-15
    Sponsor Name:Carlos Gómez Martín
    Full Title: ENSAYO FASE I/II, MULTICENTRICO DE LA COMBINACIÓN DE CARBOPLATINO Y GEMCITABINA EN EL TRATAMIENTO DE PACIENTES CON CARCINOMA DE OVARIO EN 1ª RECIDIVA TRAS QUIMIOTERAPIA SENSIBLES A PLATINO
    Medical condition: Carcinoma de ovario en primera recidiva tras quimioterapia sensible a platino
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004686-15 Sponsor Protocol Number: LUD 03-007 Start Date*: 2005-08-04
    Sponsor Name:Ludwig Institute For Cancer Research
    Full Title: Phase I/II study of immunization with multiple peptides mixed with the immunological adjuvant CpG 7909 in HLA-A2 patients with metastatic melanoma ...
    Medical condition: HLA-A2 patients with metastatic melanoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-001378-29 Sponsor Protocol Number: RAE02 Start Date*: 2005-05-23
    Sponsor Name:Bradford Teaching Hospitals NHS Foundation Trust
    Full Title: A double blinded randomised controlled trial of injection of botulinum toxin versus normal saline into the puborectalis muscle in patients with pelvic floor dyssynergia.
    Medical condition: Obstructed defeacation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001171-36 Sponsor Protocol Number: TG-MV-001 Start Date*: 2005-05-13
    Sponsor Name:ThromboGenics Ltd.
    Full Title: A Dose-Escalation Clinical Trial of Intravitreal Microplasmin in Patients Undergoing Surgical Vitrectomy for Vitreomacular Traction Maculopathy
    Medical condition: Vitreomacular Traction Maculopathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002081-19 Sponsor Protocol Number: 252313 Start Date*: 2006-10-16
    Sponsor Name:VU University Medical Centre
    Full Title: The Effects of EGFR Inhibition on Pulmonary Arterial Hypertension Associated with Systemic Sclerosis A phase II open-label safety and efficacy study.
    Medical condition: Pulmonary arterial hypertension associated with systemic sclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002389-21 Sponsor Protocol Number: NWCOG-3 Start Date*: 2006-09-04
    Sponsor Name:North Wales NHS Trust
    Full Title: A phase I/II study of Docetaxel (Taxotere, TM), Cisplatinum and Capecitabine (Xeloda, TM) (TCX) in patients with advanced oesophago-gastric cancer.
    Medical condition: Locally advanced or metastatic adenocarcinoma, squamous cell carcinoma or undifferentiated carcinoma of the oesophagus, oesophago-gastric junction or stomach.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10055102 Oesophageal cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002895-32 Sponsor Protocol Number: ML21308 Start Date*: 2007-08-29
    Sponsor Name:Roche AB
    Full Title: A phase II trial assessing Metronidazol Actavis 1% topical cream in the prevention and treatment of Erlotinib associated rash
    Medical condition: Erlotinib associated rash
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004566-16 Sponsor Protocol Number: CSPP100A2238 Start Date*: 2007-03-12
    Sponsor Name:Novartis Pharma Services AG
    Full Title: Part 1: An open Label Pilot Study to Determine Interstitial and Tissue Concentrations of Aliskiren and Effects on the Renin-Angiotensin System (RAS) in Fat and Skeletal Muscle of Hypertensive Patie...
    Medical condition: Hypertension
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022169-91 Sponsor Protocol Number: ONC-2010-002 Start Date*: 2011-06-30
    Sponsor Name:ISTITUTO CLINICO HUMANITAS
    Full Title: PHASE II STUDY WITH BENDAMUSTINE GEMCITABINE AND VINORELBINE (BeGEV) AS INDUCTION THERAPY IN RELAPSED/REFRACTORY HODGKIN’S LYMPHOMA PATIENTS BEFORE HIGH DOSE CHEMOTHERAPY WITH AUTOLOGOUS HEMATOPOIE...
    Medical condition: patients with relapsed-refractory Hodgkin's Lymphoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10020266 Hodgkin's disease recurrent PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10020267 Hodgkin's disease refractory PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002152-26 Sponsor Protocol Number: ISRCTN86894066 Start Date*: 2009-01-20
    Sponsor Name:The Royal Marsden Foundation Trust and The Institute of Cancer Research
    Full Title: Randomised double-blind controlled phase III trial of hyperbaric oxygen therapy in patients suffering long-term adverse effects of radiotherapy for pelvic cancer
    Medical condition: Chronic radiation-induced gastrointestinal symptoms
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10057480 Hyperbaric oxygen therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-004511-39 Sponsor Protocol Number: DCC04AM005 Start Date*: 2005-04-29
    Sponsor Name:Dr. Theiss Naturwaren GmbH
    Full Title: Double blind (observer Blind) Placebo controlled, clinical-experimental Study of the Phase II for the examination of the local tolerance by Duhring-Chamber-Test as well as open user trial of the pr...
    Medical condition: healthy subjects with normal skin conditions
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000482-35 Sponsor Protocol Number: ARA102198 Start Date*: 2004-10-11
    Sponsor Name:GlaxoSmithKline Research & Development Ltd.
    Full Title: A randomised, double-blind, placebo-controlled, parallel group study to investigate the anti-inflammatory and metabolic effects of rosiglitazone XR, 8mg once daily, in subjects with rheumatoid arth...
    Medical condition: Rheumatoid Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004632-40 Sponsor Protocol Number: AGO 2005/ANE/propsev Start Date*: 2005-11-25
    Sponsor Name:University Hospital Ghent
    Full Title: Study on the pharmacodynamic interactions between propofol and sevoflurane during induction of anesthesia.
    Medical condition: Anesthesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002180-90 Sponsor Protocol Number: Hypergliom2005 Start Date*: Information not available in EudraCT
    Sponsor Name:Neurologische Uniklinik Regensburg
    Full Title: Lókoregionale Tiefenhyperthermie begleitend zu ACNU in der Rezidivtherapie von Patienten mit malignen Gliomen (WHO°III/IV)- Phase I/II-Studie
    Medical condition: Recurrent malignant glioma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-004282-34 Sponsor Protocol Number: 2833 Start Date*: 2006-10-13
    Sponsor Name:Royal Marsden NHS Foundation Trust
    Full Title: A phase II study of bethanechol chloride to treat pseudomembranous candidosis in cancer patients with salivary gland dysfunction.
    Medical condition: Oral candidosis (pseudomembranous subtype)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-006174-97 Sponsor Protocol Number: BST22006 Start Date*: 2007-05-02
    Sponsor Name:University of Oxford, Research Governance & Clinical Trials Office
    Full Title: Which oxygen saturation level should we use for very premature infants? A randomised controlled trial (BOOST-II UK)
    Medical condition: Respiratory distress of newborn ICD codes P22.0, P22.8, P22.9
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-007042-35 Sponsor Protocol Number: 2005/07 Start Date*: 2008-04-04
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Phase II trial of transdermic buprenorfine in children with pain cancer
    Medical condition: pain cancer in children
    Disease: Version SOC Term Classification Code Term Level
    6.1 10027484 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010736-18 Sponsor Protocol Number: C1 1207 Start Date*: 2009-05-04
    Sponsor Name:Pharming Technologies B.V.
    Full Title: An open-label exploratory Phase II study of the safety and prophylactic effect of a weekly 50 U/kg rC1INH treatment in asymptomatic patients with hereditary C1INH deficiency (HAE)
    Medical condition: Explore the effect of rC1INH in patients with HAE in preventing the occurence of acute HAE attacks.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2011-004155-39 Sponsor Protocol Number: BAY1000394/14858 Start Date*: Information not available in EudraCT
    Sponsor Name:Bayer Healthcare AG
    Full Title: Phase Ib / II study of BAY 1000394 in combination with cisplatin / etoposide or carboplatin / etoposide as first-line therapy in subjects with extensive disease small cell lung cancer
    Medical condition: Subjects with histologically or cytologically confirmed, extensive disease SCLC without prior systemic antitumor therapy are eligible. Subjects should have evaluable or measurable disease.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041068 Small cell lung cancer extensive stage PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2015-002516-33 Sponsor Protocol Number: NCT01420393 Start Date*: 2015-09-03
    Sponsor Name:University of Ottawa Heart Institute
    Full Title: A Randomized Ablation-based atrial Fibrillation rhythm control versus rate control Trial in patients with heart failure and high burden Atrial Fibrillation
    Medical condition: The study is comparing two accepted treatment methods (rhythm control-Catheter ablation with or without anti-arrhythmic drug control of maintaining sinus rhythm versus rate controls with medical th...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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