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Clinical trials for II

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    11,926 result(s) found for: II. Displaying page 99 of 597.
    EudraCT Number: 2009-015837-55 Sponsor Protocol Number: RAA09-004 Start Date*: 2010-08-17
    Sponsor Name:Kings College London [...]
    1. Kings College London
    2. South London and Maudsley NHS Foundation Trust
    Full Title: Double-blind, 36 month, placebo-controlled trial of mifepristone on cognition in alcoholics
    Medical condition: Alcoholism
    Disease: Version SOC Term Classification Code Term Level
    18.0 10037175 - Psychiatric disorders 10001639 Alcoholism PT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001459-38 Sponsor Protocol Number: KTP-004 Start Date*: 2019-12-10
    Sponsor Name:Karus Therapeutics Limited
    Full Title: A Phase II study of selective HDAC6 inhibition with KA2507 in advanced biliary tract cancer previously treated with standard of care chemotherapy (ABC-11)
    Medical condition: Advanced Biliary Tract Cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-001709-25 Sponsor Protocol Number: CCR5119 Start Date*: 2020-02-06
    Sponsor Name:The Institute of Cancer Research
    Full Title: Randomised phase II trial testing efficacy of intra-tumoural hydrogen peroxide as a radiation sensitiser in patients with locally advanced/recurrent breast cancer
    Medical condition: Patients with locally advanced/recurrent breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2004-001452-36 Sponsor Protocol Number: XM02-02-INT Start Date*: 2004-06-30
    Sponsor Name:BioGeneriX
    Full Title: Efficacy and Safety of XM 02 compared to Filgrastim in patients with breast cancer receiving chemotherapy. Multinational, multicentre, randomised, controlled study
    Medical condition: Patients with breast cancer high risk stage II or stage III/IV (classification according to American Joint Committee on Cancer [AJCC] receiving chemotherapy and developing Neutropenia due to chemot...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000638-35 Sponsor Protocol Number: CZOL446N2312 Start Date*: 2004-09-15
    Sponsor Name:Novartis Sverige AB
    Full Title: A 2-year randomized, multicenter, double-blind, placebocontrolled study to determine the efficacy and safety of intravenous zoledronic acid 5 mg administered either annually at randomization and 12...
    Medical condition: Postmenopausal Osteoporosis
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-002376-42 Sponsor Protocol Number: ASL603LIOM02 Start Date*: 2005-01-12
    Sponsor Name:G.O.N.O. - GRUPPO ONCOLOGICO NORD OVEST
    Full Title: PHASE II TRIAL OF SEQUENTIAL CHEMO-IMMUNOTHERAPY WITH CAPECITABINE PLUS INTERFERON ALPHA2a FOLLOWED BY IL-2 IN PATIENTS WITH METASTATIC KIDNEY CANCER
    Medical condition: TREATMENT OF METASTATIC KIDNEY CANCER
    Disease: Version SOC Term Classification Code Term Level
    6.1 10050018 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001902-10 Sponsor Protocol Number: 2006/168 Start Date*: 2006-05-31
    Sponsor Name:Kirurgisk Forskningsafsnit, Herning Sygehus
    Full Title: Effects of caffeine on people suffering from intermittens claudication. Three double blinded, placebo-controlled cross-over studies and a follow-up study.
    Medical condition: Intermittens claudication, peripheral arterial disease (PAD) Atherosclerotic disease of the lower extremities
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003737-33 Sponsor Protocol Number: 2006-07 Start Date*: 2006-10-05
    Sponsor Name:Örebro University Hospital
    Full Title: Continuous Intraperitoneal Infusion of Local Anesthetics vs. Patient Controlled Intraperitoneal injection for Postoperative Pain relief following Abdominal Hysterectomy. A randomized, double-blind ...
    Medical condition: Postoperative pain after open abdominal hysterectomy
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001841-32 Sponsor Protocol Number: SVS20-ESP-03-02 Start Date*: 2006-06-23
    Sponsor Name:TRBChemedica
    Full Title: Eficacia y Seguridad de SVS20 en pacientes con síndrome de ojo seco moderado bilateral: Estudio Piloto de 3 meses, fase II, aleatorio de pares correspondientes, controlado y enmascarado para el eva...
    Medical condition: Ojo Seco
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004008-38 Sponsor Protocol Number: NG 06/06 Start Date*: 2006-10-24
    Sponsor Name:University Medical Center Utrecht
    Full Title: The Breast CARE Study: Capecitabine (Xeloda®) combined with RHenium-188-HEDP in breast cancer patients with bone metastses; a Re-188-HEDP phase I dose escalation study and phase II efficacy study.
    Medical condition: Breast cancer with painful bone metastases.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027475 Metastatic breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-004309-69 Sponsor Protocol Number: SPaCe-01 Start Date*: 2005-01-13
    Sponsor Name:GISCAD
    Full Title: A randomized phase II study of gemcitabine/cisplatin with or without Cetuximab to evaluate the efficacy in patients with locally advanced or metastatic EGFR-positive pancreatic cancer. SpaCe TRIAL.
    Medical condition: Locally advanced or metastatic EGFR-positive pancreatic cancer.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10015674 HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001037-98 Sponsor Protocol Number: 2203/07 Start Date*: 2008-03-10
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: The minimum effect-site concentration of propofol that is able to prevent the responses to stimuli used to evoke cranial reflexes
    Medical condition: patients undergoing general anaesthesia for elective surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021885-31 Sponsor Protocol Number: N10TIL Start Date*: 2011-03-24
    Sponsor Name:NKI-AVL
    Full Title: Randomized Phase II Study Using a Non-myeloablative Lymphocyte Depleting Regimen of Chemotherapy Followed by Infusion of Tumor Infiltrating Lymphocytes and Interleukin-2 in Metastatic Melanoma’
    Medical condition: Patients with metastatic (stage IV) melanoma will be randomized to either treatment arm A (dacarbazine) or treatment arm B (TIL) after metastasectomy and feasibility of culturing of TIL.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10053571 Melanoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-014906-33 Sponsor Protocol Number: UCL/08/0254 Start Date*: 2010-09-17
    Sponsor Name:University College London
    Full Title: A Pilot study of Response to Velcade combination chemotherapy in AL amyloidosis (REVEAL)
    Medical condition: Systemic AL amyloidosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021428 - Immune system disorders 10002022 Amyloidosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-021224-10 Sponsor Protocol Number: interscalaenus block 1.0 Start Date*: 2010-09-02
    Sponsor Name:Universitätsklinik für Anästhesie,Intesivmedizin und Schmerztherapie,Mediniz.Universität Wien
    Full Title: The Impact of Interscalene Brachial Plexus Blockade on Postoperative Function after Shoulder Surgery
    Medical condition: The impact of interscalene brachial plexus blockade on postoperative function after shoulder surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-006717-32 Sponsor Protocol Number: 554 Start Date*: 2007-01-31
    Sponsor Name:Stefan Lundeberg
    Full Title: Pharmacokinetic study of the opioid ketobemidone in children and adolescens after intravenous administration
    Medical condition: Pain treatment with opioids in children
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001656-13 Sponsor Protocol Number: K/599 Start Date*: 2006-10-19
    Sponsor Name:Cassella-med
    Full Title: Multizentrischer, randomisierter, doppelblinder, Placebo-kontrollierter Parallelgruppenvergleich zum Nachweis der Wirksamkeit und Unbedenklichkeit von Cineol im Rahmen der Langzeittherapie bei Pati...
    Medical condition: Asthma bronchiale
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003418-25 Sponsor Protocol Number: CTU/2014/120 Start Date*: 2016-03-29
    Sponsor Name:MeiraGTx UK II Ltd
    Full Title: An Open-label, Multi-centre, Phase I/II Dose Escalation Trial of an Adeno-Associated Virus Vector (AAV2/5-OPTIRPE65) for Gene Therapy of Adults and Children with Retinal Dystrophy associated with D...
    Medical condition: Leber Congenital Amaurosis (LCA) caused by mutations in RPE65
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10070667 Leber's congenital amaurosis PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001545-15 Sponsor Protocol Number: 307720 Start Date*: 2004-11-04
    Sponsor Name:Schering AG
    Full Title: Estudio multicéntrico, doble ciego, aleatorizado, controlado con placebo de Testogel® (testosterona 50–100mg) para evaluar su eficacia y seguridad en hombres que presentan síntomas típicos de defic...
    Medical condition: Déficit Androgénico parcial en la edad avanzada.
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: ES (Completed) IE (Completed)
    Trial results: View results
    EudraCT Number: 2010-019206-16 Sponsor Protocol Number: EBP-FHC-2010-3 Start Date*: 2010-05-12
    Sponsor Name:Medicinsk Forskning, Regionshospitalet Holstebro
    Full Title: Effekten af atorvastatin på NO-systemet patienter med type 2 diabetes med nefropati
    Medical condition: Diabetisk Nefropati Formålet er at måle effekten af atorvastatin på L-NMMA inducerede ændringer i den renale tubulære transport af natrium og vand , central hæmodynamik og vasoaktive hormoner hos...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012638 Diabetes with renal manifestations LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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