Clinical trials

The European Union Clinical Trials Register allows you to search for protocol and results information on:

interventional clinical trials that are conducted in the European Union (EU) and the European Economic Area (EEA);

clinical trials conducted outside the EU / EEA that are linked to European paediatric-medicine development.

Learn more about the EU Clinical Trials Register including the source of the information and the legal basis.

The EU Clinical Trials Register currently displays 35340 clinical trials with a EudraCT protocol, of which 5785 are clinical trials conducted with subjects less than 18 years old.
The register also displays information on 18700 older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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Trials with a EudraCT protocol (961)
Paediatric studies in scope of Art45 of the Paediatric Regulation (0)

961 result(s) found. Displaying page 28 of 49.

EudraCT Number: 2007-005367-10

Sponsor Protocol Number: CRAF265A2101

Start Date*: 2009-05-18

Sponsor Name:Novartis Pharma Services AG

Full Title: A Phase I/II, open-label, dose escalation trial to evaluate the safety, pharmacokinetics, and pharmacodynamics of RAF265 (CHIR-265) administered orally to patients with locally advanced or metastat...

Medical condition: local advanced or metastatic melanoma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10027481	Metastatic melanoma	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Completed)

Trial results: View results

EudraCT Number: 2010-023584-17

Sponsor Protocol Number: RAS-AZIC

Start Date*: 2012-08-31

Sponsor Name:Universität Leipzig

Full Title: Response-Adapted Sequential Azacitidine And Chemotherapy in Patients > 60 Years Old With Newly Diagnosed AML Eligible for Chemotherapy and allogeneic hematopoietic cell transplantation: A Multicent...

Medical condition: acute myeloid leukeamia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	19.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000880	Acute myeloid leukaemia	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: (No results available)

EudraCT Number: 2008-007365-23

Sponsor Protocol Number: MOR-002

Start Date*: 2009-03-12

Sponsor Name:BioMarin Pharmaceutical Inc.

Full Title: A Phase 1/2, Multicenter, Open-Label, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Efficacy of BMN 110 in Subjects with Mucopolysaccharidosis IVA (Morquio Syndrome)

Medical condition: Mucopolysaccharidosis Type IV A

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10028095	Mucopolysaccharidosis IV	LLT

Population Age: Children, Adolescents, Under 18, Adults

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2015-002900-10	Sponsor Protocol Number: APD001	Start Date*: 2016-01-29
Sponsor Name:UCB Celltech, UK Registered Branch of UCB Pharma SA
Full Title: AN OPEN-LABEL EXPLORATORY STUDY OF UCB5857 IN SUBJECTS WITH ACTIVATED PHOSPHOINOSITIDE 3 KINASE (PI3K) DELTA SYNDROME (APDS)
Medical condition: Activated PI3K delta Syndrome (APDS)
Disease:
Population Age: Adolescents, Under 18, Adults		Gender: Male, Female
Trial protocol: IT (Completed) DE (Completed) ES (Completed) FR (Completed)
Trial results: View results

EudraCT Number: 2014-001333-88	Sponsor Protocol Number: ACTION	Start Date*: 2014-10-16
Sponsor Name:Academic Medical Center
Full Title: A phase Ib/II study on the addition of Nab-paclitaxel (Abraxane) to capecitabine and oxaliplatin in the first-line treatment of metastastasized oesophagogastric carcinoma
Medical condition: Metastasized oesophagogastric carcinoma
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: NL (Completed)
Trial results: (No results available)

EudraCT Number: 2017-000648-16

Sponsor Protocol Number: BAY59-7939/19365

Start Date*: 2017-06-21

Sponsor Name:Bayer AG

Full Title: Single-dose, open-label, randomized, 2-way crossover bioequivalence study of 10 mg granules for oral suspension rivaroxaban versus 10 mg tablets rivaroxaban under fasted condition in healthy subjects

Medical condition: Prevention and treatment of thromboembolic disorders

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	19.1	100000004866	10043640	Thrombosis venous	LLT

Population Age: Adults

Gender: Male

Trial protocol: DE (Completed)

Trial results: View results

EudraCT Number: 2015-001443-36

Sponsor Protocol Number: ARQ087-101

Start Date*: 2015-08-05

Sponsor Name:ARQULE INC

Full Title: A Phase 1/2 Study of ARQ 087 in Adult Subjects with Advanced Solid Tumors with FGFR Genetic Alterations, Including Intrahepatic Cholangiocarcinoma with FGFR2 Gene Fusion

Medical condition: Advanced Solid Tumors with FGFR Genetic Alterations, Including Intrahepatic Cholangiocarcinoma with FGFR2 Gene Fusion

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.1	100000004864	10065143	Malignant solid tumour	LLT
	20.0	100000004864	10073077	Intrahepatic cholangiocarcinoma	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Completed)

Trial results: (No results available)

EudraCT Number: 2006-005341-11

Sponsor Protocol Number: rhASA-01

Start Date*: 2006-12-28

Sponsor Name:Shire Pharmaceuticals Ireland Limited

Full Title: A single center, open-label, non-randomized, uncontrolled, multiple-dose, dose escalation study of the safety, pharmacokinetics and efficacy of Metazym (recombinant human arylsulfatase A or rhASA) ...

Medical condition: Late infantile metachromatic leukodystrophy (MLD)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10024381	Leukodystrophy	LLT

Population Age: Infants and toddlers, Children, Under 18

Gender: Male, Female

Trial protocol: DK (Completed)

Trial results: View results

EudraCT Number: 2015-002530-50

Sponsor Protocol Number: EspeRare_RIM_001

Start Date*: 2015-11-04

Sponsor Name:EspeRare

Full Title: A phase Ib, open label study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending oral doses of Rimeporide in patients with Duchenne Muscular Dystrophy.

Medical condition: Duchenne Muscular Dystrophy (DMD)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	18.1	10010331 - Congenital, familial and genetic disorders	10013801	Duchenne muscular dystrophy	PT

Population Age: Children, Adolescents, Under 18

Gender: Male

Trial protocol: ES (Completed) GB (Completed) FR (Completed) IT (Completed)

Trial results: View results

EudraCT Number: 2017-000609-18

Sponsor Protocol Number: BAY59-7939/19366

Start Date*: 2017-06-20

Sponsor Name:Bayer AG

Full Title: Single-dose, open-label, randomized, 2-way crossover bioequivalence study of 20 mg granules for oral suspension rivaroxaban versus 20 mg tablets rivaroxaban under fed condition in healthy subjects

Medical condition: Prevention and treatment of thromboembolic disorders

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	19.1	100000004866	10043640	Thrombosis venous	LLT

Population Age: Adults

Gender: Male

Trial protocol: DE (Completed)

Trial results: View results

EudraCT Number: 2013-001294-24

Sponsor Protocol Number: ONEnTreg13

Start Date*: 2014-11-18

Sponsor Name:Medizinischen Klinik mit Schwerpunkt Nephrologie und Internistische Intensivmedizin/Charité - Universitätsmedizin Berlin

Full Title: The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation – Natural regulatory T-cells (nTregs) Trial.

Medical condition: Kidney allograft rejection following living-donor renal transplantation.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	16.1	100000004865	10050436	Prophylaxis against renal transplant rejection	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: (No results available)

EudraCT Number: 2017-002577-18

Sponsor Protocol Number: APR-633

Start Date*: 2017-12-13

Sponsor Name:APREA THERAPEUTICS AB

Full Title: A phase I/IIa study to investigate the safety and clinical activity of APR-246 in combination with dabrafenib in patients with BRAF V600 mutant unresectable metastatic melanoma resistant to dabrafe...

Medical condition: BRAF V600 Mutant Metastatic Melanoma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004864	10027481	Metastatic melanoma	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: BE (Completed)

Trial results: (No results available)

EudraCT Number: 2010-022160-13

Sponsor Protocol Number: H9H-MC-JBAI

Start Date*: 2011-02-21

Sponsor Name:Eli Lilly and Company

Full Title: Phase 1b/2a Study Combining LY2157299 with Standard Temozolomide-based Radiochemotherapy in Patients with Newly Diagnosed Malignant Glioma

Medical condition: Glioblastoma Multiforme (GBM)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10018337	Glioblastoma multiforme	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: View results

EudraCT Number: 2011-000259-17

Sponsor Protocol Number: PazTo_2010

Start Date*: 2012-04-20

Sponsor Name:Charité - Universitätsmedizin Berlin

Full Title: A phase I/II study of Pazopanib and weekly Topotecan in patients with platinum-resistant or intermediate-sensitive recurrent ovarian cancer

Medical condition: This study is a prospective single-arm, open-label, multicenter phase I/II trial. The phase I-trial is a dose-escalation trial to determine the maxium tolerated dose (MTD) of pazopanib in combinati...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	19.0	100000004864	10033131	Ovarian carcinoma	LLT

Population Age: Adults, Elderly

Gender: Female

Trial protocol: DE (Completed)

Trial results: (No results available)

EudraCT Number: 2014-004805-34

Sponsor Protocol Number: TDU13828-ACT13830

Start Date*: 2015-04-02

Sponsor Name:Sanofi-aventis Research & Development

Full Title: A Two Part Protocol Using Double Blind Placebo Control to Assess the Safety, Tolerability, and Pharmacokinetics of Single Escalating Intra-articular Doses Followed by Assessment of Efficacy, Safety...

Medical condition: Osteoarthritis

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10028395 - Musculoskeletal and connective tissue disorders	10031161	Osteoarthritis	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: View results

EudraCT Number: 2018-001775-20	Sponsor Protocol Number: CHDR1644	Start Date*: 2018-07-12
Sponsor Name:Centre for Human Drug Research
Full Title: Immunomonitoring of tacrolimus in healthy volunteers
Medical condition: Immunesuppression
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: NL (Completed)
Trial results: (No results available)

EudraCT Number: 2015-004360-10

Sponsor Protocol Number: ALN-HBV-001

Start Date*: 2016-04-06

Sponsor Name:Alnylam Pharmaceuticals, Inc

Full Title: A Phase 1/2, Randomized, Single-Blind, Placebo-Controlled, Single-Ascending and Multiple-Ascending Dose, Safety, Tolerability, Pharmacokinetics, and Antiviral Efficacy Study of Subcutaneously Admin...

Medical condition: Chronic Hepatitis B virus (HBV) Infection

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	18.1	10021881 - Infections and infestations	10008910	Chronic hepatitis B	PT

Population Age: Adults

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2011-006197-88

Sponsor Protocol Number: FANCOSTEM-1

Start Date*: 2012-03-22

Sponsor Name:Cristina Díaz de Heredia Rubio

Full Title: Clinical Phase II Trial to evaluate efficacy and safety of CD34+ cells mobilization and collection after treatment with plerixafor and filgrastim in patients with Fanconi anemia for subsequent tra...

Medical condition: Fanconi anemia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10010331 - Congenital, familial and genetic disorders	10055206	Fanconi's anemia	LLT

Population Age: Children, Adolescents, Under 18, Adults

Gender: Male, Female

Trial protocol: ES (Completed)

Trial results: (No results available)

EudraCT Number: 2009-016853-16

Sponsor Protocol Number: MGN1601-CT1

Start Date*: 2010-08-31

Sponsor Name:MOLOGEN AG

Full Title: A Phase I/II, Proof-of-Principle, Multi-Center, Open-Label, Single-Arm, Non-randomized Clinical Study to Assess Safety and Efficacy of a Tumor Vaccine Consisting of Genetically Modified Allogeneic ...

Medical condition: Advanced renal cell carcinoma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	17.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10038394	Renal cancer stage IV	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: (No results available)

EudraCT Number: 2007-005405-21

Sponsor Protocol Number: UMCN-AKF 07.06

Start Date*: 2008-01-21

Sponsor Name:Radboud University Nijmegen Medical Centre

Full Title: The influence of Raltegravir (MK_0518) on the pharmacokinetics of single-dose Lamotrigine in healthy male subjects (GRANOLA)

Medical condition: HIV infection

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10020161	HIV infection	LLT

Population Age: Adults

Gender: Male

Trial protocol: NL (Completed)

Trial results: View results

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