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Clinical trials for Additive effect

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    49 result(s) found for: Additive effect. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2006-004427-11 Sponsor Protocol Number: 060317 Start Date*: 2006-10-27
    Sponsor Name:Univ of Lund, Dept of Pediatrics
    Full Title: Effects of Omega-3-Fatty Acids on Arterial Endothelial Function and Intima Media Thickness in Children with Insulin-Dependent Diabetes Mellitus
    Medical condition: Diabetes mellitus type 1 in children
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003377-97 Sponsor Protocol Number: KLLVACC-2018 Start Date*: 2018-12-18
    Sponsor Name:Swedish CLL-group
    Full Title: Long term effect on immune response after pneumococcal vaccination in patients with chronic lymphocytic leukemia and evaluation of the effect of revaccination.
    Medical condition: The aim of the study is to evaluate pneumococcal vaccination strategy with PPSV23 and PCV13 in patients with chronic lymphocytic leukemia (CLL) initially randomized in a clinical study.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004674-27 Sponsor Protocol Number: 14076 Start Date*: 2007-02-14
    Sponsor Name:Dutch Kidney Foundation
    Full Title: Effect of GM-CSF on development of antigen-specific T cell responses following hepatitis B vaccination
    Medical condition: Haemodialysis patients are susceptible for infections due to a continuous mildly activated immune system. About 40% of the haemodialysis patients does not respond to the standard HBV vaccination pr...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10018487 GM-CSF prophylaxis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010863-18 Sponsor Protocol Number: NL26548.101.09 Start Date*: 2010-06-25
    Sponsor Name:Amphia ziekenhuis
    Full Title: The additive effect of short contact tar-derivates to UVB therapy in “en plaque” psoriasis: a prospective single blind unicenter randomized clinical trial
    Medical condition: Psoriasis patient getting UVB lighttherapy in a dermatological daycare center
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015581 Exacerbation of psoriasis LLT
    9.1 10037153 Psoriasis LLT
    9.1 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002175-42 Sponsor Protocol Number: GernerDex001 Start Date*: 2011-10-12
    Sponsor Name:Paracelsus Medizinische Universität - Universitätsklinik für Anästhesie
    Full Title: The effect and safety of dexmedetomidine as an additive to ropivacaine for interscalene brachial plexus blocks for shoulder surgery
    Medical condition: The goal of the present study is to investigate the safety and efficiacy of dexmedetomidine added to ropivacaine for interscalene brachial plexus nerve block for shoulder surgery in humans. Provi...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2020-002756-21 Sponsor Protocol Number: 1663/2020 Start Date*: 2021-02-23
    Sponsor Name:Department of Cardiothoracic Anesthesia and Intensive Care Medicine, Medical University of Vienna
    Full Title: Plasma Pharmacokinetics of Prophylactic Cefazolin Administered for Cardiac Surgery: Comparison of Cardiopulmonary Bypass Priming with Additive Human Albumin 20% vs.Pure Crystalloid Priming: A singl...
    Medical condition: This is a pharmacokinetic trial for patients undergoing cardiac surgery. It will be investigated whether cardiopulmonary bypass priming substituted with human albumin 20% has an effect on the pharm...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-000869-38 Sponsor Protocol Number: VGSKAS-12916 Start Date*: 2008-06-02
    Sponsor Name:Skaraborg Hospital
    Full Title: Impact of Losartan in hypertensive men with obstructive sleep apnea
    Medical condition: Hypertension and obstructive sleep apnea (OSA)
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006948-65 Sponsor Protocol Number: Version 4 Start Date*: 2007-11-29
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: The effect of acidosis correction and exercise on tissue wasting and immune function in renal patients
    Medical condition: Chronic kidney disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-005814-28 Sponsor Protocol Number: 17099.2901 Start Date*: 2008-11-24
    Sponsor Name:Erasmus MC
    Full Title: Cost-effectiveness of viscosupplementation therapy for patients with osteoarthritis of the knee: a randomized clinical trial
    Medical condition: osteoarthritis of the knee
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005231-28 Sponsor Protocol Number: 31121976-1 Start Date*: 2008-10-01
    Sponsor Name:Med. Univ. Wien, Universitätsklinik für Anästhesie, allgemeine Intensivmedizin und Schmerzmedizin
    Full Title: Postoperative Analgesie and Antihyperalgesia of Tramadol and Acetaminophen peroral after Caesarean Section
    Medical condition: Pain after Cesarean Section in spinal anesthesia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-021188-34 Sponsor Protocol Number: LT2380-PIII-05/10 Start Date*: 2011-07-01
    Sponsor Name:Laboratoires Théa
    Full Title: Efficacy and safety assessment of intracameral T2380 (Fixed combination of lidocaine, phenylephrine and tropicamide) for mydriasis and anaesthesia in phacoemulsification cataract surgery
    Medical condition: The aim of this clinical study will be to develop a combination of active substances enabling to obtain at the same time a mydriasis and an anaesthesia during cataract surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10011719 Cycloplegia PT
    14.1 10042613 - Surgical and medical procedures 10002325 Anesthesia local LLT
    14.1 10015919 - Eye disorders 10028521 Mydriasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) DE (Completed) BE (Completed) AT (Completed) ES (Ongoing) SE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-007881-45 Sponsor Protocol Number: SPP100ANL02T Start Date*: 2009-03-12
    Sponsor Name:University Medical Center Groningen
    Full Title: A double-blind, placebo-controlled, randomized trial investigating the safety and efficacy of Additive Renin Inhibition with Aliskiren on renal blood flow and Neurohormonal Activation in patients w...
    Medical condition: Patients with chronic heart failure and reduced glomerular filtration rate.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038443 Renal failure and impairment HLT
    9.1 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-004142-35 Sponsor Protocol Number: ABSALON Start Date*: 2023-04-18
    Sponsor Name:Department of Ophthalmology, Rigshospitalet
    Full Title: Additive Benefits of Semaglutide for open-AngLe glaucoma – an Opportunity for Neuroprotection (ABSALON)
    Medical condition: mild and moderate glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10036719 Primary open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-002600-18 Sponsor Protocol Number: 43/2007/O/Sper Start Date*: 2007-06-05
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: EVALUATION OF THE RELATIONSHIP BETWEEN INFLAMMATION-PHYSICAL ACTIVITY AND THE ACTIVITY OF THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS
    Medical condition: Abdominal obesity with metabolic syndrome
    Disease: Version SOC Term Classification Code Term Level
    6.1 10052066 PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-002010-35 Sponsor Protocol Number: TinnEx Start Date*: 2006-12-14
    Sponsor Name:Prof. Herta Flor, Head of the Institute of Clinical and Cognitive Neuroscience
    Full Title: An Extinction Training in Tinnitus
    Medical condition: The effect of pregabalin on the success to reduce the interference by tinnitus by an extinction training is tested in chronic tinnitus sufferers.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001888-21 Sponsor Protocol Number: DPM-CF-203 Start Date*: 2004-12-03
    Sponsor Name:Pharmaxis Ltd
    Full Title: A cross-over comparative study of inhaled mannitol, alone and in combination with daily rhDNase, in children with cystic fibrosis
    Medical condition: Cystic fibrosis (CF)
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-000990-35 Sponsor Protocol Number: FARM12.PW7R_A6-DeprEpil Start Date*: 2019-02-06
    Sponsor Name:DIP. MEDICINA DEI SISTEMI UNIVERSITà DEGLI STUDI DI ROMA TOR VERGATA
    Full Title: EFFECTS OF ANTIDEPRESSANT TREATMENT WITH AGOMELATINE ON PATIENTS AFFECTED BY DEPRESSION AND EPILEPSY. A DOUBLE BLIND RANDOMIZED STUDY WITH ACTIVE CONTROL (ESCITALOPRAM) WITH PARALLEL GROUPS.
    Medical condition: Depression in patients affected by epilepsy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10032061 Other forms of epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003321-32 Sponsor Protocol Number: 108 Start Date*: 2021-01-21
    Sponsor Name:Hvidovre Hospital, Dep. of Orthopaedic Surgery
    Full Title: Evaluation of intra articular Tranexamic acid for reduction of total blood loss in total hip arthroplasty
    Medical condition: The benefit of additional Tranexamic Acid (TXA) injected intra-articular at the end of surgery for patients undergoing a unilateral total hip arthroplasty in addition to conventional IV TXA to redu...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10003397 Arthroplasty of hip LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-000559-15 Sponsor Protocol Number: FB2012 Start Date*: 2012-09-14
    Sponsor Name:FinnBladder
    Full Title: TREATMENT OF Ta BLADDER CANCER WITH HIGH RISK OF RECURRENCE – FLUORESCENCE CYSTOSCOPY WITH OPTIMIZED ADJUVANT MITOMYCIN-C
    Medical condition: bladder cancer (non-invasive Ta urothelial bladder cancer)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2009-012642-22 Sponsor Protocol Number: 0887x1-20003 Start Date*: 2009-12-18
    Sponsor Name:Swedish CLL-group
    Full Title: A Randomized Phase III Trial to Determine Whether Conjugated Pneumococcal Vaccine Can Improve the Immune Responsiveness Compared to Polyclonal Pneumococcal Vaccine in Patients With Untreated Chroni...
    Medical condition: The purpose of the study is to determine wheter patients with chronic lymphocytic leukaemia (CLL) will benefit from vaccination with conjugated pneumococcal vaccine compared to conventional 23-vale...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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