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Clinical trials for Amphotericin B

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    41 result(s) found for: Amphotericin B. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2005-003609-96 Sponsor Protocol Number: AMB ELF Start Date*: 2005-09-07
    Sponsor Name:Medical University, Dpt. Internal Medicin, Division of General Internal Medicine
    Full Title: Amphotericin B Spiegel in bronchoalveolären Lavagen (Epithelial Lining Fluid) unter Behandlung mit lipidformuliertem Amphotericin B (Amphotericin B levels in broncho-alveolar lavage [epithelial lin...
    Medical condition: Plasma and ELF concentrations of lipidformulatied amphotericin b will be measured in patients requiring treatment with lipid-formulated amphotericin B for fungal pneumonia (proven or suspected).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001795-37 Sponsor Protocol Number: AMB TS Start Date*: 2007-07-19
    Sponsor Name:Medical University Innsbruck, Dpt. Internal Medicine, Div. Internal Medicine
    Full Title: WIRKORTKONZENTRATIONEN VON AMPHOTERICIN B FORMULIERUNGEN IN ASZITES, LIQUOR, PLEURAERGUSS, GALLE UND LIQUOR BEI KRITISCH KRANKEN (Target-site concentrations of Amphotericin B preparations in ascit...
    Medical condition: Plasma and target-site (ascites, pleural effusion, bile and cerebrospinal fluid) concentrations of amphotericin B preparations will be measured in critically ill patients, requiring treatment with ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-000266-21 Sponsor Protocol Number: ABCD HEP Start Date*: 2007-07-19
    Sponsor Name:Medical University, Dpt. Internal Medicine, Div. of General Internal Medicine
    Full Title: PHARMAKOKINETIK VON KOLLOIDALEM AMPHOTERICIN B BEI KRITISCH KRANKEN MIT EINGESCHRÄNKTER LEBERFUNKTION (Pharmacokinetics of colloidal Amphotericin B in critically ill Patients with hepatic impairme...
    Medical condition: Plasma concentrations of colloidal Amphotericin B will be measured in critically ill Patients with hepatic impairment and with normal liver function, both requiring treatment with Amphocil, to dete...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-003406-28 Sponsor Protocol Number: LF AMB AD Start Date*: 2005-09-07
    Sponsor Name:Medical University, Dpt. Internal Medicin, Division of General Inteal Medicine
    Full Title: Pharmakokinetik von lipid-formuliertem Amphotericin B unter Albumindialyse (Pharmacokinetics of lipid-formulated amphotericin B during albumin dialysis)
    Medical condition: Plasma concentrations of lipidformulated amphotericin B will be measured in patients requiring treatment with lipid-formulated amphotericin B for systemic fungal infection (proven or suspected) an...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-005021-13 Sponsor Protocol Number: MK-0991-044 Start Date*: 2015-04-03
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Multicenter, Double-Blind, Randomized, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin Versus (Amphotericin B) Liposome for Injection as Empirical Therapy in P...
    Medical condition: Empirical Therapy in Pediatric Patients
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2013-000371-32 Sponsor Protocol Number: 13-02/AM-MG Start Date*: 2014-10-06
    Sponsor Name:Dermapharm AG
    Full Title: Randomised, double-blind, vehicle controlled trial comparing Amphotericin B 100.000 I.E./g oral gel vs. Ampho-Moronal® suspension vs. modified vehicle to suspension in adult patients with oropharyn...
    Medical condition: Oropharyngeal candidiasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10050346 Oropharyngeal candidiasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-010943-15 Sponsor Protocol Number: ICU_AMB_1 2009-010943-15 Start Date*: 2009-08-26
    Sponsor Name:Intensive Care Unit, The Adelaide and Meath Hospital Incorporating the National Children's Hospital
    Full Title: Determination of Pharmacokinetic Parameters of Amphotericin B in critically ill patients during continuous veno-venous haemodiafiltration.
    Medical condition: Critically ill patients with systemic fungal infection.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005030-20 Sponsor Protocol Number: Ematonco/divmalinf/2006.6 Start Date*: 2007-02-16
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: Secondary prophylaxis of invasive mycosis in immunocompromised patients by means of a weekly high dose of liposomal Amphotericin B
    Medical condition: Invasive fungal infection in immunocompromised patients
    Disease: Version SOC Term Classification Code Term Level
    8.1 10052366 Systemic mycosis LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005031-21 Sponsor Protocol Number: Ematonco/divmalinf/2006.5 Start Date*: 2007-02-16
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: Nebulized liposomial Amphotericin B as rescue treatment of pulmonary and or sinusal invasive fungal infection
    Medical condition: Invasive fungal infection of the respiratory tract
    Disease: Version SOC Term Classification Code Term Level
    6.1 10017537 HLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005032-34 Sponsor Protocol Number: MK-0991-058 Start Date*: 2015-02-27
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Multicenter, Sequential-Panel, Open-Label, Noncomparative Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Caspofungin Acetate in Neonates and Infants Less Than 3 Months of ...
    Medical condition: Empirical therapy for fungal infections
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-001924-11 Sponsor Protocol Number: 37/2007/O/Sper Start Date*: 2007-06-05
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Primary fungal profilaxis with Liposomal Amphotericin B at the dose of 10 mg/kg a week in adult patient undergoing orthotopic liver transplantation and high risk for postoperative fungal infection:...
    Medical condition: Postoperative fungal infection.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10052366 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002084-26 Sponsor Protocol Number: MK0991-064 Start Date*: 2017-01-27
    Sponsor Name:Merck Sharp & Dohme Corp.
    Full Title: A Multicenter, Double-Blind, Randomized, Comparator-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin Versus Amphotericin B Deoxycholate in the Treatment of Invasiv...
    Medical condition: Invasive Candidiasis
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004862 10064954 Invasive candidiasis LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: BG (Prematurely Ended) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2012-000780-24 Sponsor Protocol Number: 9463-CL-2303 Start Date*: 2012-07-24
    Sponsor Name:Astellas Pharma Global Development, Inc.
    Full Title: A Phase 3, Randomized, Double-Blind, Multi-Center Study to Compare the Efficacy and Safety of Micafungin Versus Amphotericin B Deoxycholate for the Treatment of Neonatal Candidiasis
    Medical condition: Neonatal Candidiasis
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GR (Completed) HU (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2014-003306-33 Sponsor Protocol Number: UMCN-AKF-14.04 Start Date*: 2017-01-17
    Sponsor Name:Radboud university medical center
    Full Title: Liposomal amphotericin B (Ambisome) pharmacokinetics given as a single intravenous dose to obese patients (ASPEN).
    Medical condition: Prophylaxis for patients at risk for invasive fungal infection due to gastric bypass surgery.
    Disease: Version SOC Term Classification Code Term Level
    17.1 10021881 - Infections and infestations 10017533 Fungal infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-005210-20 Sponsor Protocol Number: 2005-005210-20 Start Date*: 2006-04-10
    Sponsor Name:CHU Sart-Tilman
    Full Title: Phase II trial of caspofungin as secondary prophylaxis for invasive fungal infections in patients with high-risk hematological malignancies undergoing intensive chemotherapy or hematopoietic stem ...
    Medical condition: Acute leukemia during induction or consolidation therapy. Autologous HSCT for a hematological malignancy. Standard allogeneic HSCT with a myeloablative conditioning regimen.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002211-28 Sponsor Protocol Number: 36713 Start Date*: 2012-11-07
    Sponsor Name:VU medical center
    Full Title: Perioperative selective decontamination of the digestive tract (SDD) in elective colorectal cancer patients: a multicenter randomized clinical trial
    Medical condition: Post-operative infective complications and long term oncological outcome in patients undergoing surgery for colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004862 10059428 Postoperative infection LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004988-27 Sponsor Protocol Number: FG-463-21-20 Start Date*: 2006-07-27
    Sponsor Name:Astellas Pharma BV
    Full Title: A PHASE II, MULTICENTRE, RANDOMISED, OPEN-LABEL, ACTIVE CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF MICAFUNGIN SALVAGE MONO THERAPY VERSUS ACTIVE CONTROL INTRAVENOUS SALVAGE MONO THE...
    Medical condition: Patients with haematopoietic stem cell transplantation (HSCT), acute leukaemia, myelodysplastic syndrome (MDS) and with proven (probable only in case of pulmonary aspergillosis) invasive aspergillo...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10022881 Invasive bronchopulmonary aspergillosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) BE (Completed) ES (Completed) HU (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-002335-14 Sponsor Protocol Number: LAMBDA Start Date*: 2018-12-05
    Sponsor Name:AOU DI BOLOGNA POLICLINICO S.ORSOLA-MALPIGHI
    Full Title: A ß-d-glucan guided antifungal stewardship strategy for the management of patients with severe abdominal sepsis. A multicenter interventional explorative study with a pharmadynamic/pharmachokinetic...
    Medical condition: Patients with severe sepsis or septic shock
    Disease: Version SOC Term Classification Code Term Level
    23.1 10021881 - Infections and infestations 10066593 Post procedural sepsis PT
    20.0 10021881 - Infections and infestations 10058040 Abdominal sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-019194-15 Sponsor Protocol Number: CRCFC-ABLC003 Start Date*: 2010-05-12
    Sponsor Name:AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
    Full Title: Esplorative study to evaluate the tolerability of Amphotericin B lipid complex (Abelcet) by aerosol in patients with Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis (ABPA)
    Medical condition: Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis (ABPA)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021881 SOC
    9.1 10011762 PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000499-32 Sponsor Protocol Number: FSJD-ABELNEB-2010 Start Date*: 2011-09-29
    Sponsor Name:FUNDACIÓ SANT JOAN DE DEU
    Full Title: A PHASE II CLINICAL TRIAL TO EVALUATE THE SAFETY AND TOLERABILITY OF AMPHOTERICIN B LIPID COMPLEX (ABELCET®) FOR THE PROPHYLAXIS OF INVASIVE PULMONARY ASPERGILLOSIS DURING PROLONGED NEUTROPENIA IN ...
    Medical condition: Invasive pulmonary aspergillosis in patients with acute myeloblastic or lymphoblastic leukaemia.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10022881 Invasive bronchopulmonary aspergillosis LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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