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Clinical trials for Anesthetic agents

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    13 result(s) found for: Anesthetic agents. Displaying page 1 of 1.
    EudraCT Number: 2019-001534-34 Sponsor Protocol Number: 260319 Start Date*: 2022-03-11
    Sponsor Name:Odense University Hospital
    Full Title: Propofol and thiopental for intravenous induction in neonates: a dose finding study
    Medical condition: Any condition requiring general anesthesia.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10018061 General anesthesia LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-001850-83 Sponsor Protocol Number: 2012/175/HP Start Date*: 2013-08-02
    Sponsor Name:CHU- Hôpitaux de Rouen
    Full Title: Adaptation to neonatal life after an anesthetic protocol using remifentanil for general anesthesia for caesarean section in a context of prematurity - REAGI Protocol (Remifentanil for General Anes...
    Medical condition: pregnant woman older than 18 years with an indication for caesarean section under general anesthesia in a context of prematurity.
    Disease: Version SOC Term Classification Code Term Level
    18.0 10036585 - Pregnancy, puerperium and perinatal conditions 10026908 Maternal complications of pregnancy HLGT
    Population Age: Preterm newborn infants, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008193-31 Sponsor Protocol Number: 2008/44 Start Date*: Information not available in EudraCT
    Sponsor Name:Hopital Foch
    Full Title: Impact des facteurs chronologiques et démographiques sur les posologies per-opératoires des agents anesthésiques (Etude prospective multicentrique)
    Medical condition: general anesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002323 Anesthesia general LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-003737-19 Sponsor Protocol Number: CHUB-ITF-sevo-propofol Start Date*: 2023-01-10
    Sponsor Name:CHU Brugmann
    Full Title: Influence of sevoflurane and propofol on maximum muscular strength, speed of contraction and relaxation, in humans: A pilot study.
    Medical condition: Impact of anesthetic drugs on neuromuscular transmission
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001496-21 Sponsor Protocol Number: LOC-2013 Start Date*: 2013-06-18
    Sponsor Name:Harry Scheinin
    Full Title: The Neural Mechanisms of Anesthesia and Human Consciousness
    Medical condition: No medical condition or disease involved. The study subjects are healthy volunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004982-10 Sponsor Protocol Number: LOC-2016 Start Date*: 2015-12-15
    Sponsor Name:Harry Scheinin
    Full Title: The Neural Mechanisms of Anesthesia and Human Consciousness (Part 6)
    Medical condition: No medical condition or disease involved. The study subjects are healthy volunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001668-21 Sponsor Protocol Number: FDE_2014_25 Start Date*: Information not available in EudraCT
    Sponsor Name:Fondation Ophtalomologique A. de Rothschild
    Full Title: Addition of neuromuscular-blocking agents during induction in infants: potential interest in reducing hypoxia episodes
    Medical condition: Chirurgie programmée sous anesthésie générale avec intubation orotrachéale, avec induction inhalatoire prévue
    Disease: Version SOC Term Classification Code Term Level
    21.0 10042613 - Surgical and medical procedures 10002326 Anesthetic induction LLT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003279-28 Sponsor Protocol Number: LT2380-PII-11/07 Start Date*: 2008-07-24
    Sponsor Name:Laboratoires Théa
    Full Title: Efficacy and safety assessment of intracameral T2380 (Fixed combination of lidocaïne, phenylephrine and tropicamide) for anaesthesia and mydriasis in phacoemulsification cataract surgery
    Medical condition: The aim of the development was to develop a combination of active substances enabling to obtain at the same time a mydriasis and an anaesthesia during cataract surgery.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002325 Anesthesia local LLT
    9.1 10011719 Cycloplegia PT
    9.1 10028521 Mydriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing) ES (Ongoing) BE (Completed) PT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001761-42 Sponsor Protocol Number: 0869-131 Start Date*: 2006-06-12
    Sponsor Name:Merck & Co., Inc
    Full Title: A Randomized, Double-Blind, Active Comparator-Controlled, Parallel-Group Study Conducted Under In-House Blinding Conditions, to Examine the Safety, Tolerability, and Efficacy of Aprepitant for the ...
    Medical condition: Postoperative Nausea and Vomiting
    Disease: Version SOC Term Classification Code Term Level
    8.1 10036238 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001738-33 Sponsor Protocol Number: I14032 Start Date*: 2015-09-24
    Sponsor Name:CHU de LIMOGES
    Full Title: Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion for third trimester voluntary termination of pregnancy analgesia : a randomized study.
    Medical condition: Termination Pregancy
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10015011 Epidural anaesthesia PT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2006-003231-71 Sponsor Protocol Number: NOT APPLICABLE Start Date*: 2006-12-08
    Sponsor Name:Dept of Anaesthesia, University College Hospital, Galway
    Full Title: Determination of the efficacy of the Transversus Abdominis Plane Block in the management of postoperative pain in children post open abdominal surgery.
    Medical condition: Postoperative pain in children post open abdominal surgery
    Disease: Version SOC Term Classification Code Term Level
    8.1 10054711 Postoperative pain LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000188-33 Sponsor Protocol Number: MK-8616-146 Start Date*: 2017-10-27
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase 4 Randomized, Active-Comparator Controlled Trial to Study the Efficacy and Safety of Sugammadex (MK-8616) for the Reversal of Neuromuscular Blockade Induced by Either Rocuronium Bromide or ...
    Medical condition: Reversal of neuromuscular blockade
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10018061 General anesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) BE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-004679-37 Sponsor Protocol Number: GECOP-MMC Start Date*: Information not available in EudraCT
    Sponsor Name:Hospital Universitario de Fuenlabrada
    Full Title: Phase IV multicentric clinical trial to evaluate the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) with Mytomicin-C after complete surgical cytoreduction in patients with Colon Canc...
    Medical condition: Surgical resection combined with intraperitoneal chemotherapy (CT) is the best treatment for selected patients with Peritoneal Metastases from colon cancer. However, the real role of intraperitonea...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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