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Clinical trials for Antibiotic resistance

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    The EU Clinical Trials Register currently displays   44364   clinical trials with a EudraCT protocol, of which   7388   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    120 result(s) found for: Antibiotic resistance. Displaying page 1 of 6.
    1  2  3  4  5  6  Next»
    EudraCT Number: 2005-004211-30 Sponsor Protocol Number: 2005-23 Start Date*: 2005-10-17
    Sponsor Name:The Norwegian Radium Hospital
    Full Title: Penicillin G and an aminoglycoside versus meropenem as initial empiric antibiotic therapy in lymphoma and leukemia patients with febrile neutropenia
    Medical condition: Lymphoma and leukemia patients with febrile neutropenia
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004290-29 Sponsor Protocol Number: BY 221 OM2 Start Date*: 2004-11-29
    Sponsor Name:University of Oxford
    Full Title: Randomised controlled trial of effect of antibiotic dose on antibiotic resistance in young children with otitis media
    Medical condition: Acute otitis media
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-000244-10 Sponsor Protocol Number: EGBAB Start Date*: 2019-12-13
    Sponsor Name:Region Uppsala
    Full Title: Influence of antibiotic treatment on the normal flora and the presence of resistance genes in known carriers of ESBL and VRE
    Medical condition: Carriage of genes coding for vancomycin resistant enterococci (VRE) and extended spectrum betalactamase producing enterobacteriales (EPE) phenotypes.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-003378-28 Sponsor Protocol Number: 2013071339 Start Date*: 2014-04-09
    Sponsor Name:Department of Medicine, Køge University Hospital [...]
    1. Department of Medicine, Køge University Hospital
    2. Department of Medicine, Køge University Hospital
    Full Title: THE ROLE OF PHAGES IN MICROBIAL GUT ECOLOGY A STUDY OF INTERACTIONS BETWEEN ANTIBIOTICS AND THE GUT MICROBIOTA IN HEALTHY VOLUNTEERS A PARALLEL, SINGLE-BLIND, RANDOMIZED, CONTROLLED STUDY
    Medical condition: Resistance to anitbiotics
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10004052 Bacterial resistance LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-001708-14 Sponsor Protocol Number: ABOGRAFT-01 Start Date*: 2021-06-29
    Sponsor Name:Region Östergötland
    Full Title: Antibiotic Impregnated Bone Graft to reduce infection in hip replacement. The ABOGRAFT trial
    Medical condition: Patients scheduled for any type of hip arthroplasty requiring bone grafting
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-002556-32 Sponsor Protocol Number: ANTIC:6672 Start Date*: 2013-09-05
    Sponsor Name:The Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: Antibiotic treatment for intermittent bladder catheterisation: A randomised controlled trial of once daily prophylaxis (The AnTIC study)
    Medical condition: Recurrent urinary tract infection in people who use intermittent bladder catheterisation.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10064736 Antibiotic prophylaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-003704-31 Sponsor Protocol Number: ARG-16 Start Date*: 2019-05-17
    Sponsor Name:Uppsala University
    Full Title: Impact on the intestinal microbiota during antibiotic treatment
    Medical condition: Impact on the intestinal microbiota during antibiotic treatment
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023889-52 Sponsor Protocol Number: AntiResDev-SWE Start Date*: 2011-01-18
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Effects of Clindamycin and Ciprofloxacin administration on the emergence, prevalence and persistence of antibiotic-resistant bacteria in humans
    Medical condition: To assess the effect of ciprofloxacin and clindamycin administration on the proportions and types of cultivable antibiotic-resistant bacteria that emerge in the oropharynx, on the skin and in the...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003487-36 Sponsor Protocol Number: 1 Start Date*: 2015-12-23
    Sponsor Name:The Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: Alternatives to prophylactic antibiotics for the treatment of recurrent urinary tract infection in women
    Medical condition: Recurrent urinary tract infection in women
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10064736 Antibiotic prophylaxis PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000334-59 Sponsor Protocol Number: PI2017_843_0002 Start Date*: 2018-06-05
    Sponsor Name:CHU Amiens-Picardie
    Full Title: The value of post-operative antibiotic therapy after laparoscopic appendectomy for complicated acute appendicitis (other than for generalized peritonitis): a prospective, randomized, placebo-contro...
    Medical condition: The value of post-operative antibiotic therapy after laparoscopic appendectomy for complicated acute appendicitis (other than for generalized peritonitis): a prospective, randomized, placebo-contro...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-004297-14 Sponsor Protocol Number: SLH2015001 Start Date*: 2016-06-08
    Sponsor Name:Streeklaboratorium voor de volksgezondheid Kennemerland
    Full Title: Effectiveness of fosfomycin versus nitrofurantoin in Dutch risk groups with cystitis: a pilot study (Uri-weg study)
    Medical condition: Cystitis without tissue invasion (uncomplicated cytitis)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004921-25 Sponsor Protocol Number: 848018006 Start Date*: 2020-08-17
    Sponsor Name:Amsterdam UMC
    Full Title: Safe shortening of antibiotic treatment duration for complicated Staphylococcus aureus bacteremia
    Medical condition: Unnecessary long-term exposure to antibiotics can cause adverse events such as renal and hepatic toxicity, health-care-related infections and antibiotic resistance. Staphylococcus aureus bacteremia...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-003727-22 Sponsor Protocol Number: CER13266 Start Date*: 2015-05-26
    Sponsor Name:Geneva University Hospitals
    Full Title: A randomized controlled multicenter trial of a five day course of oral colistin and neomycin followed by restoration of the gut microbiota using fecal transplantation to eradicate intestinal carr...
    Medical condition: Intestinal colonization with extended-spectrum beta-lactamse or carbapenemase producing enterobacteriaceae
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004862 10071097 Beta-lactam antibiotic resistance LLT
    18.1 100000004862 10069718 Bacterial colonization LLT
    18.1 100000004862 10028152 Multi-antibiotic resistance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004084-10 Sponsor Protocol Number: T001018N Start Date*: 2022-05-16
    Sponsor Name:Flemisch Fund for Scientific Research - Fonds voor Wetenschappelijk Onderzoek
    Full Title: Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment; a pragmatic randomised controlled trial
    Medical condition: Rifampicin resistant (RR-TB) and drug resistant (DR-TB) tuberculosis
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022891 - Investigations 10049031 Genotype drug resistance test PT
    20.1 10018065 - General disorders and administration site conditions 10048723 Multiple-drug resistance PT
    20.0 10018065 - General disorders and administration site conditions 10059866 Drug resistance PT
    20.0 100000004862 10004052 Bacterial resistance LLT
    20.0 100000004862 10038637 Resistance bacterial LLT
    20.1 100000004862 10028152 Multi-antibiotic resistance LLT
    20.0 10022891 - Investigations 10070974 Antibiotic resistance test LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2019-000953-30 Sponsor Protocol Number: EPAAC Start Date*: 2019-07-25
    Sponsor Name:Uppsala University Hospital
    Full Title: Effects of phenoximetylpenicillin, amoxicillin and amoxicillin-clavulanic acid on the gut microbiota of healthy volunteers: a randomized clinical trail
    Medical condition: Effects of phenoximetylpenicillin, amoxicillin and amoxicillin-clavulanic acid on the gut microbiota of healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004447-36 Sponsor Protocol Number: ZonMw848015005 Start Date*: 2017-06-23
    Sponsor Name:Stichting Rotterdams Onderzoeksconsortium Kindergeneeskunde
    Full Title: INTRAVENOUS-TO-ORAL ANTIBIOTIC SWITCH THERAPY FOR SUSPECTED NEONATAL BACTERIAL INFECTIONS: CLINICAL EFFICACY, SAFETY AND COST-EFFECTIVENESS
    Medical condition: Neonatal probable bacterial infection
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001941-41 Sponsor Protocol Number: RC10-18 Start Date*: 2020-04-21
    Sponsor Name:IRCCS MATERNO INFANTILE BURLO GAROFOLO
    Full Title: Shortened antibiotic therapy for febrile urinary tract infections (UTI) in childhood: a multicentre randomized controlled trial
    Medical condition: FEBRILE URINARY TRACT INFECTION
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10000822 Acute kidney infection LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000899-16 Sponsor Protocol Number: UMM022013TG Start Date*: 2013-10-16
    Sponsor Name:Department of Pharmacy Unversitätsmedizin Mainz
    Full Title: Investigation of pharmacokinetics of Linezolid and Meropenem in patients receiving continuous renal replacement therapy
    Medical condition: Sepsis and acute renal failure (ARF) are pathological entities that commonly co-exist in patients admitted to intensive care. Antibiotic dosing in septic patients with ARF can be complicated and ma...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001257-14 Sponsor Protocol Number: P160910J Start Date*: 2018-04-13
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Temocillin versus a carbapenem as initial intravenous treatment for extended-spectrum beta-lactamase related urinary tract infections, a non-inferiority study.TEMO-CARB
    Medical condition: -Hospitalized patient with complicated UTI due to ESBL producing enterobacteriaceae (pyelonephritis, prostatitis or renal abscess) requiring parenteral antimicrobial therapy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10054088 Urinary tract infection bacterial PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-002578-37 Sponsor Protocol Number: OPHT-240518 Start Date*: 2019-04-25
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: The effect of antibiotic eye drops on the nasal microbiome in healthy subjects
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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