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Clinical trials for Aortic surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    130 result(s) found for: Aortic surgery. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2012-003391-39 Sponsor Protocol Number: 9026 Start Date*: 2012-10-26
    Sponsor Name:University Hospital of Montpellier
    Full Title: Ballon aortic valvuloplasty performed without heparin to decrease vascular and bleeding complications of the procedure
    Medical condition: Aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10002906 Aortic stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000518-34 Sponsor Protocol Number: 0107 Start Date*: 2011-10-25
    Sponsor Name:Rikshospitalet
    Full Title: Effect of beta blockade on left ventricular remodeling and function in aortic regurgitation
    Medical condition: The aim of the present study is therefore to assess the effect of a 6 month treatment with beta-blocker on left ventricular remodeling and function in patients with asymptomatic moderate to severe ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10002904 Aortic regurgitation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-001456-39 Sponsor Protocol Number: Tranex-AAA Start Date*: 2015-01-05
    Sponsor Name:IRCCS Ospedale San Raffaele
    Full Title: Tranexamic acid in major vascular surgery (Tranex-AAA)
    Medical condition: abdominal aortic aneurysm
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004866 10000054 Abdominal aortic aneurysm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-002736-24 Sponsor Protocol Number: TicAAA-1.0 Start Date*: 2014-01-29
    Sponsor Name:Uppsala University
    Full Title: Does Ticagrelor inhibit growth of small abdominal aortic aneurysms? A randomised controlled trial (TicAAA)
    Medical condition: Small abdominal aortic aneurysm
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004866 10000051 Abdominal aneurysm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003818-92 Sponsor Protocol Number: CURITIBA_TRIAL Start Date*: 2014-12-22
    Sponsor Name:Ospedale San Raffaele, UO Chirurgia Vascolare
    Full Title: CUstodiol vs RInger: whaT Is the Best Agent?
    Medical condition: Thoracoabdominal aortic aneurysm
    Disease: Version SOC Term Classification Code Term Level
    17.1 10047065 - Vascular disorders 10002882 Aortic aneurysm PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-004612-31 Sponsor Protocol Number: BI3023_2002 Start Date*: 2008-05-29
    Sponsor Name:CSL Behring GmbH
    Full Title: Efficacy and safety of Haemocomplettan® P in patients experiencing acute bleeding while undergoing aortic replacement surgery
    Medical condition: Acute bleeding while undergoing aortic replacement surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061651 Aortic surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-016823-74 Sponsor Protocol Number: CDZ-PE-002 Start Date*: 2010-01-27
    Sponsor Name:Cardoz AB
    Full Title: An open pilot study to assess the effects of pemirolast on C-reactive protein levels in subjects with coronary artery disease.
    Medical condition: Cardoz AB intends to develope pemirolast as an anti-inflammatory agent. The first intended indication for the product under development is abdominal aortic aneurysm. The proposed clinical study...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10000054 Abdominal aortic aneurysm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-002448-25 Sponsor Protocol Number: MA3RSTrial Start Date*: 2012-10-02
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian Health Board
    Full Title: Magnetic Resonance Imaging Using Ultrasmall Superparamagnetic Particles of Iron Oxide in Patients Under Surveillance for Abdominal Aortic Aneurysms to Predict Rupture or Surgical Repair: the MA3RS ...
    Medical condition: Abdominal Aortic Aneurysm
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2022-000513-14 Sponsor Protocol Number: NBK154/2/2021 Start Date*: 2023-03-08
    Sponsor Name:Medical University of Gdańsk
    Full Title: Evaluation of the Efficacy of Valsartan in Slowing Down Aortic Root Dilatation in Children and Young Adults with Marfan-type Heritable Thoracic Aortic Diseases – Valsar-TAD, a randomised, double-b...
    Medical condition: Marfan Syndrome Diseases related to Marfan syndrome (rare diseases with aneurysms of the thoracic aorta and dissection of the aorta), among others: Loeys-Dietz syndrome, Vascular type of Ehlers-Da...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-001382-26 Sponsor Protocol Number: HCS-2014-2 Start Date*: 2014-06-09
    Sponsor Name:TAYS Sydänsairaala
    Full Title: Adenosine in initial cardioplegia
    Medical condition: Coronary artery disease, aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    16.1 10047065 - Vascular disorders 10002906 Aortic stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2014-004604-29 Sponsor Protocol Number: 210710120713 Start Date*: 2015-04-27
    Sponsor Name:Jens Rolighed Larsen
    Full Title: Sevoflurane versus standard general anesthesia in elective open abdominal aortic aneurism surgery
    Medical condition: Abdominal aortic aneurism
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10002885 Aortic aneurysm repair PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-004289-33 Sponsor Protocol Number: MAAAGI Start Date*: 2019-12-12
    Sponsor Name:Department of Surgical, Sciences Uppsala University
    Full Title: Metformin for Abdominal Aortic Aneurysm Inhibition A randomized controlled trial MAAAGI trial
    Medical condition: Small abdominal aortic aneurysm (AAA) under active surveillance; 30-49 mm in diameter for men and 30-44 mm in diameter for women
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned) DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-001859-39 Sponsor Protocol Number: TEDY Start Date*: 2013-10-02
    Sponsor Name:Leiden University Medical Center
    Full Title: TElmisartan in the management of abDominal aortic aneurYsm (TEDY)
    Medical condition: Abdominal aortc aneurysm
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10000051 Abdominal aneurysm LLT
    14.1 10047065 - Vascular disorders 10002889 Aortic aneurysms and dissections HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019302-16 Sponsor Protocol Number: 2010GU001B Start Date*: 2010-09-13
    Sponsor Name:Royal Brompton and Harefield NHS Foundation Trust
    Full Title: A prospective, randomised, placebo-controlled, double blind, multi-centre study of the effects of Irbesartan on aortic dilatation in Marfan syndrome
    Medical condition: Marfan Syndrome
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-000077-57 Sponsor Protocol Number: 2021-THORANE-Pharma-001 Start Date*: 2022-06-25
    Sponsor Name:Rigshospitalet
    Full Title: Methadone versus fentanil and oxycodone for post-operative pain reduction in patients undergoing coronary artery bypass grafting and/or valve surgery – a placebo-controlled, double-blind, randomiz...
    Medical condition: We investigate the efficacy of methadonehydrochloride for reducing optoperative opioid requirements, pain scores and improving quality of recovery in patients undergoing heart surgery (i.e. corona...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10008937 Chronic ischemic heart disease, unspecified LLT
    20.0 10007541 - Cardiac disorders 10002911 Aortic valvular disorders HLT
    20.0 10007541 - Cardiac disorders 10061532 Mitral valve disease PT
    20.0 10042613 - Surgical and medical procedures 10062202 Mitral valve repair PT
    20.0 10042613 - Surgical and medical procedures 10027732 Mitral valve replacement PT
    20.0 10042613 - Surgical and medical procedures 10002916 Aortic valve replacement PT
    20.0 10042613 - Surgical and medical procedures 10061652 Aortic valve repair PT
    21.1 10042613 - Surgical and medical procedures 10011077 Coronary artery bypass PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-005784-24 Sponsor Protocol Number: MEIXO-VALV-001 Start Date*: 2012-06-14
    Sponsor Name:Andres Iñiguez Romo
    Full Title: Dual antiplatelet therapy versus oral anticoagulation for a short time to prevent cerebral embolism after percutaneous aortic valve implantation. Multicenter randomized clinical trial.
    Medical condition: Evaluate the efficacy of dual antiplatelet therapy versus oral anticoagulation for primary prevention of cerebral thromboembolism at three months after percutaneous aortic valve implantation (TAVI).
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003776-40 Sponsor Protocol Number: CL-N-CSM-AV-III/05/12 Start Date*: 2013-11-08
    Sponsor Name:Dr. Franz Köhler Chemie GmbH
    Full Title: A Prospective Randomized Double Blind Multicenter Phase III Study Comparing two Methods of Cardioplegia in Aortic Valve Surgery Custodiol-N versus Custodiol
    Medical condition: Patients with aortic valve disease and has to undergo aortic valve surgery +/- bypass surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-002376-95 Sponsor Protocol Number: RRK3535 Start Date*: 2009-01-05
    Sponsor Name:University Hospital Birmingham NHS Foundation Trust
    Full Title: Myocardial protection with Perhexiline in Left Ventricular Hypertrophy
    Medical condition: Patients with left ventricular hypertrophy undergoing aortic valve surgery (with or without coronary artery surgery)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-005224-32 Sponsor Protocol Number: OCMR 06.01 Start Date*: 2008-12-16
    Sponsor Name:University of Oxford
    Full Title: A randomised controlled trial of the angiotensin converting enzyme inhibitor ramipril in asymptomatic aortic stenosis
    Medical condition: Aortic stenosis of at least moderate degree (peak velocity >=3.0m/sec or aortic valve area <1.5cm2)
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-002701-59 Sponsor Protocol Number: IIBSP-CAR-2018-71 Start Date*: 2019-04-12
    Sponsor Name:Institut de Recerca Hospital de la Santa Creu i Sant Pau
    Full Title: Randomized, open and multi-center clinical trial to compare the efficacy and safety of Buckberg vs Del Nido cardioplegia in isolated aortic valve replacement
    Medical condition: Myocardial protection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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