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Clinical trials for Apnea-hypopnea index

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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    32 result(s) found for: Apnea-hypopnea index. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2007-002174-58 Sponsor Protocol Number: ACT6796 Start Date*: 2007-11-30
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: A double-blind, randomized, placebo-controlled, study of the safety and activity of four escalating single doses of AVE0657 in patients suffering from Obstructive Sleep Apnea Hypopnea Syndrome
    Medical condition: Patients suffering from Obstructiv-Sleep Apnea Hypopnea Syndrome (OSAHS)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055577 Obstructive sleep apnea syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) ES (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000733-37 Sponsor Protocol Number: 21402 Start Date*: 2005-08-20
    Sponsor Name:NV Organon
    Full Title: A randomized, double-blind, placebo-controlled, multicenter parallel-group dose ranging clinical trial to assess the efficacy and safety of Org 4419-2 in the treatment of obstructive sleep apnea/hy...
    Medical condition: Obstructive sleep apnea/hypopnea syndrome
    Disease: Version SOC Term Classification Code Term Level
    8.0 10055577 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-003133-33 Sponsor Protocol Number: EMG-2006 Start Date*: 2006-07-14
    Sponsor Name:Hôpital Erasme
    Full Title: Etude des effets d’un antagoniste non spécifique de l’endothéline (le bosentan) sur l’activité orthosympathique et le chémoréflexe.
    Medical condition: healthy subjects obstructive sleep apnea (Bosentan is used in clinic in pulmonary hypertension)
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015859-24 Sponsor Protocol Number: Zon-001 Start Date*: 2010-02-24
    Sponsor Name:The Sahlgrenska Academy, University of Gothenburg
    Full Title:
    Medical condition: The objective is to explore the efficacy of pharmacological weight reduction compared with CPAP treatment in patients with moderate to severe obstructive sleep apnea (OSA).
    Disease: Version SOC Term Classification Code Term Level
    12.0 10055577 Obstructive sleep apnea syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-004552-41 Sponsor Protocol Number: I8F-MC-GPI2 Start Date*: 2022-09-14
    Sponsor Name:Eli Lilly and Company
    Full Title: A Master Protocol to Investigate the Efficacy and Safety of Tirzepatide Once Weekly in Participants who have Obstructive Sleep Apnea and Obesity: A Randomized, Double-Blind, Placebo-Controlled Tria...
    Medical condition: Obstructive sleep apnea
    Disease: Version SOC Term Classification Code Term Level
    25.0 10038738 - Respiratory, thoracic and mediastinal disorders 10029983 Obstructive sleep apnoea syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2015-003095-68 Sponsor Protocol Number: ORL-DISE-2015 Start Date*: 2016-04-29
    Sponsor Name:Fundació Parc Taulí
    Full Title: Randomized cross-over open-label clinical trial to compare the videoendoscopic examination with induced sleep after sedation with propofol or clonidine
    Medical condition: Apnea hypopnea syndrome
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10040976 Sleep apnea syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001497-27 Sponsor Protocol Number: BY1023/M3-713 Start Date*: 2005-08-12
    Sponsor Name:ALTANA Pharma AG
    Full Title: Effect of pantoprazole on sleep-related breathing disorders
    Medical condition: Sleep-related breathing disorders
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-000869-38 Sponsor Protocol Number: VGSKAS-12916 Start Date*: 2008-06-02
    Sponsor Name:Skaraborg Hospital
    Full Title: Impact of Losartan in hypertensive men with obstructive sleep apnea
    Medical condition: Hypertension and obstructive sleep apnea (OSA)
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-004551-16 Sponsor Protocol Number: I8F-MC-GPI1 Start Date*: 2022-09-14
    Sponsor Name:Eli Lilly and Company
    Full Title: A Master Protocol to Investigate the Efficacy and Safety of Tirzepatide Once Weekly in Participants who have Obstructive Sleep Apnea and Obesity: A Randomized, Double-Blind, Placebo-Controlled Tria...
    Medical condition: Obstructive sleep apnea
    Disease: Version SOC Term Classification Code Term Level
    25.0 10038738 - Respiratory, thoracic and mediastinal disorders 10029983 Obstructive sleep apnoea syndrome PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004866-33 Sponsor Protocol Number: CA-BP13 Start Date*: 2014-04-04
    Sponsor Name:Göteborgs Universitet
    Full Title: A short term open, randomized cross over trial trial exploring the effect of carbonic anhydrase inhibition by acetazolamide on sleep apnea associated hypertension
    Medical condition: obstructive sleep apnea related hypertension
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004855 10055577 Obstructive sleep apnea syndrome LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000520-19 Sponsor Protocol Number: BAY2586116/20849 Start Date*: 2021-02-10
    Sponsor Name:Bayer AG
    Full Title: Proof-of-concept, multi-center, randomized, double-blind, placebo-controlled, two-way crossover study to investigate the effect strength of BAY 2586116 on the apnea-hypopnea-index after repetitive ...
    Medical condition: Sleep Apnea, Obstructive
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10055577 Obstructive sleep apnea syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2023-000062-34 Sponsor Protocol Number: Reb-Oxy-OSA Start Date*: 2023-06-02
    Sponsor Name:CHU Brugmann
    Full Title: Combination of Reboxetine 4mg and Oxybutynin 5mg for treating moderate obstructive sleep apnea: a one-month randomized placebo-controlled double-blind study
    Medical condition: Obstructive sleep apnea
    Disease: Version SOC Term Classification Code Term Level
    25.0 100000004855 10055577 Obstructive sleep apnea syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004469-15 Sponsor Protocol Number: ITRDEX-2-01 Start Date*: 2013-12-12
    Sponsor Name:Rottapharm S.p.A.
    Full Title: Effect of CCK antagonists in Obstructive Sleep Apnea (OSA) syndrome. A randomized, double-blind, cross-over study
    Medical condition: Obstructive Sleep Apnea Syndrome
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000645-23 Sponsor Protocol Number: Borealis1 Start Date*: 2015-06-19
    Sponsor Name:CIBER (Centro de Investigacion Biomedica en Red)
    Full Title: Safety, tolerability and efficacy of nocturnal hypertension treatment with domperidone in the sleep apnea-hypopnea syndrome. Pilot study.
    Medical condition: Nocturnal hypertension in the sleep apnea-hypopnea syndrome.
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004855 10040976 Sleep apnea syndrome LLT
    17.1 100000004866 10019180 HBP LLT
    Population Age: Adults Gender: Male
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005792-16 Sponsor Protocol Number: Rocuronium_HVR_OSAS Start Date*: 2012-02-10
    Sponsor Name:Karolinska University Hospital
    Full Title: Effect of reduced cholinergic transmission by rocuronium on the hypoxic ventilatory response in patients with obstructive sleep apnea - before and after three months of continous positive airway pr...
    Medical condition: Obstuctive sleep apnea and acute hypoxic ventilatory response
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10055577 Obstructive sleep apnea syndrome LLT
    Population Age: Adults Gender: Male
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003789-40 Sponsor Protocol Number: DON DF 1 Start Date*: 2005-11-11
    Sponsor Name:Pharmapnea AB
    Full Title: A randomized, four-way cross-over, double-blind, controlled study of oral donepezil (2, 5, 10 mg) in patients with moderate to severe obstructive sleep apnea.
    Medical condition: Moderate to severe obstructive sleep apnea. Males and females; aged 25 to 65 years, previously diagnosed OSA defined as an oxygen desaturation (4%) index of 15 or more per hour of sleep obtained fr...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001357-40 Sponsor Protocol Number: HDZNRW-KA_006_TB Start Date*: 2016-11-08
    Sponsor Name:Klinik für Kardiologie, Herz- und Diabeteszentrum NRW
    Full Title: High-Flow-Therapy for the treatment of Cheyne-Stokes-Respiration in chronic heart failure: A randomized, controlled, cross-over trial
    Medical condition: Cheyne-Stokes Respiration in chronic heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-005125-12 Sponsor Protocol Number: LIRALUNG Start Date*: 2016-05-12
    Sponsor Name:Dr. Albert Lecube, Ph.D., M.D.
    Full Title: MULTICENTRE RANDOMIZED DOUBLE BLIND, CROSSOVER, PLACEBO-CONTROLLED CLINICAL TRIAL TO EVALUATE THE EFFECT OF LIRAGLUTIDE ON LUNG FUNCTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS (LIRALUNG STUDY)
    Medical condition: Type 2 Diabetes
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001900-17 Sponsor Protocol Number: 2020/0431/HP Start Date*: 2022-10-24
    Sponsor Name:DRCI - CHU de Rouen
    Full Title: PILOT STUDY OF THE EFFECT OF A SUBSTANCE P ANTAGONIST, APREPITANT, ON THE SECRETION OF ALDOSTERONE IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA AND ARTERIAL HYPERTENSION SYNDROME
    Medical condition: Patients with obstructive sleep apnea syndrome with arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10052741 Endocrine and metabolic secondary hypertension HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-002127-16 Sponsor Protocol Number: UCAB-CT-03 Start Date*: 2017-08-24
    Sponsor Name:Umecrine Cognition AB
    Full Title: A phase IIa study of GR3027 in patients with idiopathic hypersomnia (IH) involving an open-label part to assess safety, tolerability and pharmacokinetics (PK) of a single oral GR3027 dose in female...
    Medical condition: Idiopathic hypersomnia (IH)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10028714 Narcolepsy and hypersomnia HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed) DK (Completed) SE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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