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Clinical trials for Attenuation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    88 result(s) found for: Attenuation. Displaying page 1 of 5.
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    EudraCT Number: 2014-000681-22 Sponsor Protocol Number: VIS-13-08 Start Date*: 2015-02-25
    Sponsor Name:ErasmusMC
    Full Title: EFFECT OF ISO-OSMOLAR CONTRAST MEDIUM ON CORONARY OPACIFICATION AND HEART RHYTHM IN CORONARY CT ANGIOGRAPHY (ISO-COR)
    Medical condition: Patients with suspected coronary artery disease and clinically referred for coronary CTA.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002608-33 Sponsor Protocol Number: KI CLINTEC mikro 02 Start Date*: 2006-10-27
    Sponsor Name:Karolinska Institute, CLINTEC, div of orthopedics
    Full Title: En dubbelblind placebokontrollerad studie för utvärdering av postoperativa analgetikaeffekter via mikrodialys synovialt på patienter som genomgår artroskopi.
    Medical condition: Painfull knee condition of traumatic or other origin, where arthroscopic surgery is indicated, as judged by the surgeon.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002241-30 Sponsor Protocol Number: CEC-3/CEL Start Date*: 2018-01-30
    Sponsor Name:Dr. Falk Pharma GmbH
    Full Title: A phase IIa, double-blind, randomised, placebo-controlled, dose-finding study on the efficacy and tolerability of a 6-week treatment with ZED1227 capsules vs. placebo in subjects with well-controll...
    Medical condition: Treatment of celiac disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004856 10007864 Celiac disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: LT (Completed) FI (Completed) DE (Completed) AT (Completed) IE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003647-19 Sponsor Protocol Number: CELIM-NRCD-001 Start Date*: 2016-02-22
    Sponsor Name:Celimmune LLC
    Full Title: A Phase 2a, Randomized, Double-Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients with Celiac Disease.
    Medical condition: Celiac disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-000267-17 Sponsor Protocol Number: VPI-103-01 Start Date*: 2007-02-21
    Sponsor Name:Verus Pharmaceuticals Inc
    Full Title: A SINGLE CENTRE, GAMMA SCINTIGRAPHY STUDY IN ASTHMATIC PATIENTS TO COMPARE PULMONARY DEPOSITION AND PHARMACOKINETICS OF ALBUTEROL INHALATION SOLUTION (AIS) DELIVERED VIA eFLOW NEBULISER AND SALBUTA...
    Medical condition: The medical condition which is under investigation is Asthma.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038738 Respiratory, thoracic and mediastinal disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-001210-13 Sponsor Protocol Number: PR IOM-101 Start Date*: 2004-11-19
    Sponsor Name:Bracco Imaging S.p.A
    Full Title: MS-CTA IN PULMONARY ARTERIES FOR THE DETECTION OF PULMONARY EMBOLI AND SUBSEQUENT FOLLOW-UP MS-CTP OF THE LOWER EXTREMITY VEINS FOR THE DETECTION OF DEEP VENOUS THROMBOSIS
    Medical condition: SUSPECTED PULMONARY EMBOLI AND/OR DEEP VENOUS THROMBOSIS MedDRA code for deep venous thrombosis: version 7 LLT 0.913
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-002437-37 Sponsor Protocol Number: 13-1-033 Start Date*: 2014-07-31
    Sponsor Name:Maastricht University Medical Centre
    Full Title: Effects on Intra-Coronary Attenuation using low iodine concentrations (240 mg, 300 mg and 370 mg iodine per ml) while maintaining identical IDR
    Medical condition: atypical or typical complaints of angina pectoris with no previous cardiovascular medical history low to intermediate risk for atherosclerosis referred for coronary CTA to rule out CAD
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-017480-42 Sponsor Protocol Number: SG005 Start Date*: 2010-03-03
    Sponsor Name:Synairgen Research Ltd
    Full Title: A randomised, double-blind, placebo-controlled Phase II study, comparing the efficacy and safety of inhaled SNG001 to placebo administered to asthmatic subjects after the onset of a respiratory vir...
    Medical condition: prevention or attenuation of asthma symptoms caused by respiratory viruses
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-002269-14 Sponsor Protocol Number: NL80263.018.21 Start Date*: 2022-08-11
    Sponsor Name:AMC, Cardiovascular Sciences
    Full Title: Dotatate to locate coronary plaques at high-risk of myocardial infarction
    Medical condition: Inflammatory atherosclerosis of the coronary arteries.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022110-29 Sponsor Protocol Number: SG006 Start Date*: 2010-10-08
    Sponsor Name:Synairgen Research Limited
    Full Title: A randomised, double-blind, placebo-controlled Phase II study, comparing the efficacy and safety of inhaled SNG001 to placebo administered to COPD patients after the onset of a respiratory viral in...
    Medical condition: Prevention or attenuation of COPD symptoms caused by respiratory viruses
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2023-000166-33 Sponsor Protocol Number: SLICK-001 Start Date*: 2023-04-12
    Sponsor Name:Semmelweis University
    Full Title: Implementation study of lipid management of high-risk cardiovascular patients- Semmelweis Lipid Center for high-risk patients
    Medical condition: primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia in atherosclerotic cardiovascular disease
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004861 10020604 Hypercholesterolemia LLT
    20.0 100000004850 10054380 Familial hypercholesterolemia LLT
    20.0 100000004850 10077966 Primary hypercholesterolemia LLT
    21.0 100000004861 10058110 Dyslipidemia LLT
    20.1 100000004861 10079969 Atherogenic dyslipidemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-002248-26 Sponsor Protocol Number: IEOS701/412 Start Date*: 2012-10-16
    Sponsor Name:ISTITUTO EUROPEO DI ONCOLOGIA
    Full Title: Prevention of anthracycline-induced cardiotoxicity: a multicentre randomizedtrial comparing two therapeutic strategies.
    Medical condition: Anthracycline-­‐induced cardiotoxicity
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10008444 Chemotherapy cardiotoxicity attenuation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004618-24 Sponsor Protocol Number: 012018CONTROL Start Date*: 2018-08-03
    Sponsor Name:IRCCS ISTITUTO CLINICO HUMANITAS
    Full Title: Evaluation of CardioprOtection by the use of betablocker Nebivolol in paTients with bReast cancer Or diffuse Large B cell lymphoma undergoing chemotherapy with anthracyclines: a randomized controll...
    Medical condition: To prevent cardiotoxicity of chemotherapeutic agents (anthracyclines)
    Disease: Version SOC Term Classification Code Term Level
    20.1 10042613 - Surgical and medical procedures 10008444 Chemotherapy cardiotoxicity attenuation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000914-23 Sponsor Protocol Number: SAFE2014 Start Date*: 2016-08-05
    Sponsor Name:DIPARTIMENTO DI SCIENZE BIOMEDICHE SPERIMENTALI E CLINICHE, UNIVERSITà DI FIRENZE
    Full Title: Cardiac toxicity prevention in non-metastatic breast cancer patients treated with anthracycline-based chemotherapy: a randomized, placebo controlled, phase 3 trial - SAFE trial.
    Medical condition: Female, non metastatic histologically confirmed primary invasive breast cancer scheduled to receive neoadjuvant or adjuvant anthracyclines with or without anti Her 2 therapy, LVEF >50%
    Disease: Version SOC Term Classification Code Term Level
    20.1 10042613 - Surgical and medical procedures 10008444 Chemotherapy cardiotoxicity attenuation PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-000371-18 Sponsor Protocol Number: 220105 Start Date*: 2005-09-23
    Sponsor Name:Portsmouth Hospitals Trust
    Full Title: The use of Thalidomide as a treatment for the cachexia of incurable upper gastrointestinal adenocarcinomas:a randomised, double-blinded, placebo controlled trial.
    Medical condition: The cachexia associated with terminal gastrointestinal adenocarcinomas
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002928-27 Sponsor Protocol Number: 2014OpaOma001 Start Date*: 2015-02-26
    Sponsor Name:VU university medical center
    Full Title: Observing Platelet Activability in a Once daily vs. a More frequent Aspirin intake regimen
    Medical condition: Stable cardiovascular disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000193-77 Sponsor Protocol Number: 05/Q1405/78 Start Date*: 2007-03-20
    Sponsor Name:The University of Manchester
    Full Title: Protective analgesia using bupivacaine and conventional release ibuprofen versus bupivacaine and sustained release ibuprofen for postoperative pain relief in patients undergoing third molar surgery...
    Medical condition: Pain following surgical removal of impacted lower wisdom tooth/ teeth.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014532-37 Sponsor Protocol Number: JU-AMG-403-1-1 Start Date*: 2011-01-13
    Sponsor Name:Universitätsklinikum Schleswig-Holstein
    Full Title: Effekte von oraler Cortisol oder Propranolol-Gabe auf die Verarbeitung alkoholbezogener Schlüsselreize, den Schlaf und das Rückfallrisiko von alkoholabhängigen Patienten (Copro-Studie).
    Medical condition: alkohol dependence
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001048-22 Sponsor Protocol Number: 990312 Start Date*: 2005-12-29
    Sponsor Name:Göteborg University, Institute for Internal Medicine
    Full Title: Rosuvastatin in Visceral Adiposity. A 26-week, single center, randomised, placebo-controlled, double-blind, parallel-group study to evaluate the effect of rosuvastatin on visceral adipose tissue in...
    Medical condition: Visceral adiposity
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000683-27 Sponsor Protocol Number: GRAY09 Start Date*: 2006-05-17
    Sponsor Name:Research and Innovation Services
    Full Title: A Placebo Controlled Trial to Evaluate The Effects of Levocetirizine on Nasal Allergen Challenge And Adenosine Monophosphate Challenge In Patients with Intermittent and Persistent Allergic Rhinitis
    Medical condition: Allergic Rhinitis - Both Persistent and Intermittent
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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