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Clinical trials for Baclofen

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
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    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    49 result(s) found for: Baclofen. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2010-021861-62 Sponsor Protocol Number: BACLAD Start Date*: 2010-12-10
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: Baclofen for the Treatment of Alcohol Dependence
    Medical condition: Alcohol Dependence
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005286-24 Sponsor Protocol Number: 22112015 Start Date*: 2016-02-24
    Sponsor Name:
    Full Title: Baclofen in managing acute alcohol withdrawal
    Medical condition: Alcohol withdrawal syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003711-51 Sponsor Protocol Number: Otto M. Lesch Start Date*: 2006-12-15
    Sponsor Name:Otto M. Lesch
    Full Title: IBIS- International Baclofen Interventional Study
    Medical condition: Preclinical pharmacological and behavioral data indicate that baclofen, a GABAB receptor agonist, modifies some neurobiological factors contributing to alcohol consumption (Cousins et al., 2001). P...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-004934-26 Sponsor Protocol Number: N/A Start Date*: 2008-11-26
    Sponsor Name:UMCG
    Full Title: Pharmacokinetics and –dynamics of intrathecal baclofen therapy in patients with spasticity
    Medical condition: Spasticity of varying origin (i.e. MS, spinal cord injury), which doesn't respond on treatment with oral medication
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041416 Spasticity LLT
    9.1 10024132 Leg spasticity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001356-22 Sponsor Protocol Number: CLR_09_21 Start Date*: 2016-07-13
    Sponsor Name:Sun Pharma Advanced Research Company Ltd.
    Full Title: A PLACEBO-CONTROLLED RANDOMIZED WITHDRAWAL EVALUATION OF THE EFFICACY AND SAFETY OF BACLOFEN ER CAPSULES (GRS) IN SUBJECTS WITH SPASTICITY DUE TO MULTIPLE SCLEROSIS
    Medical condition: Spasticity due to multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004852 10041416 Spasticity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-000368-10 Sponsor Protocol Number: NEX-426-MEI-0040-I Start Date*: 2006-08-10
    Sponsor Name:Tecnical University of Munich
    Full Title: High-dose therapy with Esomeprazol in combination with Baclofen therapy for symptomatic therapy-resistant gastrooesophageal reflux disease.
    Medical condition: Gastroesophageal reflux disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-005319-28 Sponsor Protocol Number: CNWL/AL/BACL/01 Start Date*: 2015-03-13
    Sponsor Name:Central and North West London NHS Foundation Trust
    Full Title: Improving GHB withdrawal with baclofen (The GHB Trial)
    Medical condition: GHB/GBL Withdrawal Syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-004994-30 Sponsor Protocol Number: NL68837.091.21 Start Date*: 2022-02-08
    Sponsor Name:Roessingh
    Full Title: Pulmonary function and sleep related disorders during cervical admission of intrathecal baclofen in spinal cord injury; a safety study
    Medical condition: Spasticity in patients with spinal cord injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-003418-16 Sponsor Protocol Number: Bac04018 Start Date*: 2007-02-14
    Sponsor Name:Academic Medical Center
    Full Title: The role of a hiatal hernia on the efficacy of anti-TLESR therapy in patients with gastroesophageal reflux disease
    Medical condition: Gastroesophageal reflux disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000236-16 Sponsor Protocol Number: IPX056-B06-03 Start Date*: 2007-05-28
    Sponsor Name:IMPAX Laboratories, Inc.
    Full Title: A Double-Blind, Randomized, Placebo- and Active Comparator- Controlled, Parallel Group, Multinational Study to Evaluate the Pharmacokinetics and Pharmacodynamics of IPX056 in Subjects with Establis...
    Medical condition: Established Spasticity Resulting from Multiple Sclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041416 Spasticity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2005-000436-24 Sponsor Protocol Number: AGI006-001 Start Date*: 2005-04-08
    Sponsor Name:AGI Therapeutics Limtied
    Full Title: A randomised, double-blind, placebo-controlled study of AGI 006 in the treatment of functional dyspepsia.
    Medical condition: Functional (Non-ulcer) Dyspepsia (FD; NUD)
    Disease: Version SOC Term Classification Code Term Level
    6.0 10013946 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) LT (Completed) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019768-35 Sponsor Protocol Number: ITB2010 Start Date*: 2012-07-27
    Sponsor Name:
    Full Title: Intrathecal baclofen treatment in dystonic cerebral palsy: a randomized clinical trial
    Medical condition: dytonic cerebral palsy
    Disease: Version SOC Term Classification Code Term Level
    19.1 10010331 - Congenital, familial and genetic disorders 10008129 Cerebral palsy PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017351-96 Sponsor Protocol Number: baclofen2009 Start Date*: 2009-12-23
    Sponsor Name:UZleuven
    Full Title: A placebo controlled trial with Baclofen for the treatment of GERD patients with incomplete PPI response
    Medical condition: Gastroesophageal reflux disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-007020-18 Sponsor Protocol Number: 1999/07 Start Date*: 2008-05-26
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Efficacy of baclofen in the treatment of nicotine addicted patients:randomized, double blind study of Baclofen versus placebo
    Medical condition: Smoking addiction
    Disease: Version SOC Term Classification Code Term Level
    12.0 10043903 Tobacco abuse LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000833-23 Sponsor Protocol Number: BACLOFENE INTRATECALE Start Date*: 2008-02-26
    Sponsor Name:AZIENDA OSPEDALIERA ISTITUTI CLINICI DI PERFEZIONAMENTO DI MILANO
    Full Title: Efficacy evaluation of oral baclofen treatment versus intrathecal baclofen in children with dystonic cerebral palsy
    Medical condition: Dystonic or spastic dystonic cerebral palsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029205 SOC
    9.1 10008129 PT
    9.1 10021740 LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002745-35 Sponsor Protocol Number: rum_baclofen2011 Start Date*: 2011-09-09
    Sponsor Name:UZLeuven
    Full Title: A placebo controlled trial with Baclofen for the treatment of patients with clinical suspicion of rumination syndrome or esophageal belching
    Medical condition: Rumination syndrome and supragastric belching
    Disease: Version SOC Term Classification Code Term Level
    14.0 10037175 - Psychiatric disorders 10039292 Rumination disorder LLT
    14.0 10017947 - Gastrointestinal disorders 10004222 Belching LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-011216-38 Sponsor Protocol Number: 1.02.7001 Start Date*: 2009-09-01
    Sponsor Name:Medtronic International Trading Sarl
    Full Title: A randomized, controlled, open-label, parallel-group, multicenter study to compare the effect of Intrathecal Baclofen Therapy (ITB Therapy) versus Best Medical Treatment (BMT) on severe spasticity ...
    Medical condition: Severe spasticity in post-stroke patients
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004852 10041416 Spasticity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) ES (Completed) BE (Completed) DE (Completed) IT (Completed) NL (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002565-39 Sponsor Protocol Number: 2006015 Start Date*: 2006-11-27
    Sponsor Name:South Tees Acute Hospitals NHS Trust
    Full Title: Effects of the Modification of the Daily Flow Rate with a Constant Daily Dose on Patient's Reported Analgesia in Intathecal Therapy
    Medical condition: Chronic Pain.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002824-16 Sponsor Protocol Number: 03-624 Start Date*: 2004-12-21
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Spinalt klonidin och baklofen som adjuvans till ryggmärgsstimulering vid terapiresistent smärta. (Möjlighet att förstärka den smärtlindrande effekten av alektrisk tyggmärgsstimulering med läkemedel...
    Medical condition: Neuropathic pain patients with insufficient pain-relief of trial spinal cord stimulation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000901-35 Sponsor Protocol Number: 2016-02 Start Date*: 2017-07-10
    Sponsor Name:ASISTANCE PUBLIQUE HOPITAUX DE MARSEILLE
    Full Title: Riluzole for the treatment of spasticity in the traumatic chronic spinal cord injury condition: Adaptive, Multicenter, placebo-controlled, randomised, double blind trial in a Rare Disorder” RILUSCI
    Medical condition: the traumatic chronic spinal cord injury condition
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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