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Clinical trials for Calcification

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    88 result(s) found for: Calcification. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2013-003949-41 Sponsor Protocol Number: 36810 Start Date*: 2014-11-06
    Sponsor Name:VU medical Center
    Full Title: Role of different phosphate binders on absorption of vitamin K, metabolism of matrix γ-carboxy-glutamaat (Gla) proteïne (MGP).
    Medical condition: Vascular calcification, phosphate binders and patients on hemodialysis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-005306-39 Sponsor Protocol Number: VitaminKStudy Start Date*: 2009-06-29
    Sponsor Name:RWTH Aachen University, represented by the rector, himself represented by Clinical Trial Center Aachen (CTC-A)
    Full Title: Food supplementation with Vitamin K for MGP-activation and inhibition of progression of aortic valve calcification
    Medical condition: progression of aortic valve calcification
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10050559 Aortic valve calcification PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-021264-14 Sponsor Protocol Number: 10-003 Start Date*: 2012-09-25
    Sponsor Name:RWTH Aachen University represented by the rector, himself represented by the dean of the Medical Faculty
    Full Title: Vitamin K1 to slow vascular calcification in hemodialysis patients. Multicenter, multinational, randomized controlled clinical trial
    Medical condition: dialysis patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001685-33 Sponsor Protocol Number: 07-002 Start Date*: 2007-12-28
    Sponsor Name:RWTH Aachen University
    Full Title: Prospective Comparison of Phenpocoumon (Marcumar) and Acetylsalicylic Acid (ASS) as to Progression of the Valvular and Coronary Calcification.
    Medical condition: Treatment with oral anti-coagulants prevents thromboembolic complications e.g at atrial fibrillation or artificial heart valves. Primary objective of the study is the prospective comparison of the ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019656-41 Sponsor Protocol Number: ZA/CP/0210 Start Date*: 2011-08-24
    Sponsor Name:King’s College London [...]
    1. King’s College London
    2. Guy’s and St Thomas’ NHS Foundation Trust
    Full Title: Effects of Zoledronic Acid on arterial calcification and arterial stiffness in women – a co-twin randomised double blind, placebo-controlled parallel group, clinical trial
    Medical condition: Arterial stiffness and arterial calcification
    Disease: Version SOC Term Classification Code Term Level
    14.0 10047065 - Vascular disorders 10059123 Arterial calcification LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-001719-65 Sponsor Protocol Number: CALC-SSc Start Date*: 2018-12-10
    Sponsor Name:University Medial Center Groningen
    Full Title: CALCification as an early marker of vasculopathy and organ involvement in Systemic Sclerosis CALC-SSc study
    Medical condition: Systemic sclerosis (SSc) is a rare progressive autoimmune disease hallmarked by severe vasculopathy. Patients are prone to enhanced calcification of skin and the vasculature. Active calcifications ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001865-28 Sponsor Protocol Number: 08/H0802/9 Start Date*: 2008-05-30
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Guys and St Thomas NHS Foundation Trust
    Full Title: The Relationship between Osteoporosis and Aortic Calcification in Postmenopausal Women
    Medical condition: Osteoporosis; Aortic Calcification
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10054208 Aortic calcification PT
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031285 Osteoporosis postmenopausal PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-004906-88 Sponsor Protocol Number: NL69395.042.19 Start Date*: 2020-04-24
    Sponsor Name:University Medical Center Groningen
    Full Title: Placebo-controlled double-blind randomized controlled trial investigating vitamin K supplementation on vascular calcification propensity in vitamin K deficient renal transplant recipients
    Medical condition: Vitamin K deficiency is highly prevalent among renal transplant recipients, promotes vascular calcification, and is associated with an increased risk of cardiovascular disease. Supplementation of ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003871-19 Sponsor Protocol Number: srhths01 Start Date*: 2006-09-19
    Sponsor Name:Salford Royal Hospital
    Full Title: A randomised control trial to identify the effects of cinacalcet on bone and cardiovascular health in end-stage renal disease
    Medical condition: Secondary hyperparathyroidism in renal failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002270-52 Sponsor Protocol Number: CIRIVA Start Date*: 2013-12-05
    Sponsor Name:Hospital Universitari de Girona Dr.Josep Trueta
    Full Title: Effects of cinacalcet versus conventional treatment on metabolism bone and vascular involvement in advanced chronic renal failure
    Medical condition: Bone's disorders and mineral metabolism and vascular involvement
    Disease: Version SOC Term Classification Code Term Level
    16.1 10047065 - Vascular disorders 10051753 Vascular calcification PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001978-22 Sponsor Protocol Number: I17004 Start Date*: 2019-07-31
    Sponsor Name:CHU de LIMOGES
    Full Title: Injections of Sodium Thiosulfate for ectopic calcifications or ossifications. A pilot study.
    Medical condition: Patient presenting with: - ectopic ossification secondary to iPPSD2 or - ectopic calcification secondary to dermatomyositis or - ectopic calcification secondary to systemic sclerosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004867 10006935 Calcification and ossification, unspecified LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-000434-34 Sponsor Protocol Number: UMCU-VASC-CO-003 Start Date*: 2023-04-12
    Sponsor Name:University Medical Centre Utrecht
    Full Title: A placebo-controlled, double-blind randomized trial evaluating the effect of etidronate in young patients with pseudoxanthoma elasticum on ectopic mineralization.
    Medical condition: Pseudoxanthoma elasticum
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001888-39 Sponsor Protocol Number: PGX-HT Start Date*: 2016-01-28
    Sponsor Name:OSPEDALE SAN RAFFAELE
    Full Title: PHARMACOGENOMICS HYPERTENSION : A NEW APPROACH FOR PERSONALIZED MEDICINE ( PGX - HT )
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    19.0 10047065 - Vascular disorders 10051753 Vascular calcification PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-003299-17 Sponsor Protocol Number: 22-1005-CALCIFADE Start Date*: 2023-03-20
    Sponsor Name:University Medical Center Utrecht
    Full Title: A randomized, placebo-controlled, double blind trial to study the effects of Etidronate on ectopic CALCIfication in FAhr’s Disease.
    Medical condition: Fahr’s disease or sondrome is a neurodegenerative disease in which all patients present with bilateral vessel associated calcifications in the basal ganglia in the absence of other secondary causes...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10059626 Fahr's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000421-31 Sponsor Protocol Number: Etelcalcetide-T50-CKD5D-2018 Start Date*: 2018-12-19
    Sponsor Name:Ordensklinikum Linz GmbH, ELISABETHINEN, Interne 3
    Full Title: A study to investigate the influence of PTH-lowering by Etelcalcetide (Parsabiv®) on the Calcification Propensity of Serum in Dialysis Patients
    Medical condition: End stage renal disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-005586-40 Sponsor Protocol Number: NL79407.091.21 Start Date*: 2022-05-30
    Sponsor Name:Radboudumc
    Full Title: Colchicine and Inflammation in Aortic Stenosis
    Medical condition: Aortic stenosis (AS) is the most common valvular heart disease in the developed world. The prevalence of aortic sclerosis in the general population is estimated to be 25% at the age of 65 years and...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002834-59 Sponsor Protocol Number: SNFCT2015-05 Start Date*: 2016-11-28
    Sponsor Name:Sanifit Therapeutics S.A.
    Full Title: A double-blind, randomised, placebo-controlled study to assess the effect of SNF472 on progression of cardiovascular calcification on top of standard of care in end-stage-renal-disease (ESRD) patie...
    Medical condition: Cardiovascular calcification in blood vessels in end-stage-renal-disease (ESRD) patients on haemodialysis (HD).
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004857 10014646 End stage renal disease (ESRD) LLT
    20.0 10047065 - Vascular disorders 10051753 Vascular calcification PT
    20.0 10042613 - Surgical and medical procedures 10018875 Haemodialysis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-005087-24 Sponsor Protocol Number: Version 2 23/03/2005. Start Date*: 2005-07-11
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: CIMETIDINE IN THE TREATMENT OF CALCIFIC SUPRASPINATUS TENDINITIS- A TRIAL OF CIMETIDINE 200mg B.D IN THE RESOLUTION OF CALCIFICATION IN THE SUPRASINATUS TENDON.
    Medical condition: CALCIFIC SUPRASPINATUS TENDINITIS
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-004789-24 Sponsor Protocol Number: PA21-T50-CKD5D-2016 Start Date*: 2017-03-10
    Sponsor Name:Ordensklinikum Linz, Krankenhaus der Elisabethinen Linz GmbH, III. Interne
    Full Title: The Effect of Phosphate Lowering using sucroferric oxyhydroxide (PA21) on Calcification Propensity of Serum – a randomized, controlled, open-label, cross-over trial
    Medical condition: end stage renal disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006606-16 Sponsor Protocol Number: F003MN0307_1 Start Date*: 2008-07-11
    Sponsor Name:University of Wuerzburg
    Full Title: The Effects of Paricalcitol capsules on Inflammation (CRP levels) and Calcification regulation (fetuin-A levels) in CKD stage 5D patients
    Medical condition: Chronic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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