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Clinical trials for Cardiovascular Diseases AND Cardiac Arrest

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    69 result(s) found for: Cardiovascular Diseases AND Cardiac Arrest. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2011-001074-26 Sponsor Protocol Number: S-CPR2011 Start Date*: 2011-11-17
    Sponsor Name:Medizinische Universität Graz, Universitätsklinik für Innere Medizin
    Full Title: Effect of High Dose Selenium on Inflammation and Neurological Outcome after Cardiac Arrest: A randomized, double blind placebo controlled phase 2a study
    Medical condition: Cardiac Arrest with successful resuscitation
    Disease: Version SOC Term Classification Code Term Level
    14.0 10007541 - Cardiac disorders 10007515 Cardiac arrest PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-002686-19 Sponsor Protocol Number: 2018-HJEPharma-001 Start Date*: 2018-11-07
    Sponsor Name:Department of Cardiology, Copenhagen University Hospital Rigshospitalet
    Full Title: Interleukin-6 Receptor Antibodies for Modulating the Systemic Inflammatory Response after Out-of-Hospital Cardiac Arrest
    Medical condition: We investigate the efficacy of commercially available interleukin-6 receptor antibody 'RoActemra' for reducing the systemic inflammatory response in patients having been resuscitated after out-of-h...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007515 Cardiac arrest PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-004311-45 Sponsor Protocol Number: 2013-PharmaCA-001 Start Date*: 2014-03-25
    Sponsor Name:Copenhagen University Hospital Rigshospitalet, Department of Cardiology B 2143
    Full Title: GLP-1 ANALOGS FOR NEUROPROTECTION AFTER OUT-OF-HOSPITAL CARDIAC ARREST, A RANDOMIZED CLINICAL TRIAL
    Medical condition: We investigate the efficacy of commercially available GLP-1 analog for reducing post anoxic brain injury in patients who remain comatose after having been resuscitation from out of hospital cardiac...
    Disease: Version SOC Term Classification Code Term Level
    17.0 10007541 - Cardiac disorders 10007515 Cardiac arrest PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-004773-13 Sponsor Protocol Number: 00001 Start Date*: 2018-02-27
    Sponsor Name:Research Center for Emergency Medicine Department of Clinical Medicine Aarhus University
    Full Title: Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest – A Randomized, Double-Blind, Placebo-Controlled Trial
    Medical condition: The study will include patients with in-hospital cardiac arrest (IHCA). The study will test whether treatment with methylprednisolone and vasopressin added to standard care will improve survival fo...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007515 Cardiac arrest PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-004191-35 Sponsor Protocol Number: AGO/2013/011 Start Date*: 2014-11-28
    Sponsor Name:Ghent University Hospital
    Full Title: Evaluation of the effects and plasma concentration of the potent platelet inhibitor ticagrelor, after crushed and non-crushed intake, after semi-urgent coronary bypass and in patients after cardiac...
    Medical condition: Group A: Patients who received CPR because of cardiac arrest. Group B: Patients in need of semi-urgent coronary bypass surgery, allowing interrupting the administration of ticagrelor 3 days before ...
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10063919 Bypass surgery LLT
    17.1 10007541 - Cardiac disorders 10007515 Cardiac arrest PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000792-11 Sponsor Protocol Number: Start Date*: 2014-07-09
    Sponsor Name:University of Warwick
    Full Title: Prehospital Assessment of the Role of Adrenaline: Measuring the Effectiveness of Drug administration In Cardiac arrest
    Medical condition: Out of hospital cardiac arrest
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-003047-32 Sponsor Protocol Number: IRFMN-7557 Start Date*: 2021-01-21
    Sponsor Name:IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
    Full Title: CardioPulmonary resuscitation with Argon (CPAr) trial
    Medical condition: Cardiac Arrest
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019249 Heart arrest LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-000855-11 Sponsor Protocol Number: HJE-STEROHCA-001 Start Date*: 2020-09-11
    Sponsor Name:Department of Cardiology, Copenhagen University Hospital Rigshospitalet
    Full Title: STEROID TREATMENT AS ANTI-INFLAMMATORY AND NEUROPROTECTIVE AGENT FOLLOWING OUT-OF-HOSPITAL CARDIAC ARREST. A RANDOMIZED TRIAL.
    Medical condition: We investigate the efficacy of commercially available glucocorticoid "methylprednisolone" (Solu-Medrol) for reducing the systemic inflammatory response and neurological injury in patients resuscita...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10003109 Arrest cardiac LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-001285-15 Sponsor Protocol Number: KOIIM-2019-1 Start Date*: 2019-06-28
    Sponsor Name:University Medical Centre Ljubljana
    Full Title: Platelet inhibition with cangrelor in comatose survivors of out-of-hospital cardiac arrest undergoing primary percutaneous coronary intervention
    Medical condition: Comatose survivors of out-of-hospital cardiac arrest undergoing primary percutaneous coronary intervention
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-005876-21 Sponsor Protocol Number: DANOHCA-001 Start Date*: 2022-07-08
    Sponsor Name:Department of Cardiology, Copenhagen University Hospital, Rigshospitalet
    Full Title: The Danish Out-of-Hospital Cardiac Arrest study (DANOHCA)
    Medical condition: We will investigate the efficacy of four interventions (two pharmaceutical) for reducing mortality and organ damage in patients resuscitated after out-of-hospital cardiac arrest.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10003109 Arrest cardiac LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-005922-82 Sponsor Protocol Number: IVIO1.3 Start Date*: 2022-01-13
    Sponsor Name:Prehospital Emergency Medical Services, Central Denmark Region
    Full Title: Intravenous vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest - A Randomized Clinical Trial
    Medical condition: Out-of-hospital cardiac arrest (OHCA)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10007517 Cardiac arrest transient LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-004277-41 Sponsor Protocol Number: 16.0012 Start Date*: 2017-01-18
    Sponsor Name:St George's University of London
    Full Title: An observational study into the variety of electrocardiographic responses to an ajmaline Provocation in healthy subjects. What are the genetic and structural variations dictating this response ?
    Medical condition: Study in the healthy population. This is a study of a test used in the diagnosis of the condition, Brugada Syndrome.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003109 Arrest cardiac LLT
    20.0 10007541 - Cardiac disorders 10003119 Arrhythmia PT
    20.0 10007541 - Cardiac disorders 10059027 Brugada syndrome PT
    20.1 100000004867 10042436 Sudden death unexplained LLT
    21.0 100000004848 10069779 Brugada-type ECG LLT
    20.0 100000004848 10008396 Change in ECG LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022679-71 Sponsor Protocol Number: Xenon-MTH-Studie Start Date*: 2011-01-07
    Sponsor Name:Clinical Trials Center Aachen, University of Aachen
    Full Title: Xenon and Therapeutical Hypothermia After Successful Cardiopulmonary Resuscitation
    Medical condition: In this clinical trial will be checked, whether 2 hours ventilation with xenon has neuroprotetctive effect on the patients, which had out of hospital cardiac arrest and successful cardiopulmonary r...
    Disease: Version SOC Term Classification Code Term Level
    16.1 10042613 - Surgical and medical procedures 10067221 Mechanical ventilation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-002310-39 Sponsor Protocol Number: Vasta2019 Start Date*: 2019-09-23
    Sponsor Name:Norrtälje Sjukhus, Tiohundra AB
    Full Title: VAsopressin and STeroids in addition to Adrenaline in cardiac arrest - a randomized clinical trial
    Medical condition: In hospital cardiac arrest
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-003265-26 Sponsor Protocol Number: 345 Start Date*: 2017-01-03
    Sponsor Name:Medical University of Vienna
    Full Title: Pharmacokinetic/Pharmacodynamic effects of add-on antiplatelet therapy with parenteral cangrelor as compared to standard dual antiplatelet treatment in patients with ST-elevation myocardial infarct...
    Medical condition: ST-elevation myocardial infarction, cardiac arrest
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-003387-46 Sponsor Protocol Number: COCA2 Start Date*: 2019-10-28
    Sponsor Name:Research Center for Emergency Medicine Department of Clinical Medicine Aarhus University
    Full Title: Calcium for Out-of-Hospital Cardiac Arrest – A Randomized, Double-Blind, Placebo-Controlled trial
    Medical condition: The study will include patients with out-of-hospital cardiac arrest (OHCA). The study will test whether treatment with Calcium Chloride added to standard care will improve survival following OHCA. ...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10007517 Cardiac arrest transient LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000005-23 Sponsor Protocol Number: Ghreline Start Date*: 2018-12-12
    Sponsor Name:University of Twente
    Full Title: Ghrelin treatment of comatose patients after cardiac arrest: A clinical trial to promote cerebral recovery
    Medical condition: Brain damage after cardiac arrest
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-004317-40 Sponsor Protocol Number: ADRAMIO001 Start Date*: 2014-06-23
    Sponsor Name:The Heart Centre, Rigshospitalet
    Full Title: Adrenaline versus amiodarone for out of hospital cardiac arrest due to shockable rhythms (ventricular fibrillation and pulseless ventricular tachycardia) - ADRAMIO. A randomized, double blind, mu...
    Medical condition: Out of hospital cardiac arrest due to ventricular fibrillation.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004849 10047293 Ventricular fibrillation paroxysmal LLT
    17.0 100000004849 10066685 Recurrent ventricular fibrillation LLT
    17.0 100000004849 10034048 Paroxysmal ventricular fibrillation LLT
    17.0 100000004849 10047292 Ventricular fibrillation paroxysm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-001683-37 Sponsor Protocol Number: 2018012805 Start Date*: 2018-07-03
    Sponsor Name:Rigshospitalet
    Full Title: The RIME-IVF study Investigation of RIsk factors in out-of-hospital-cardiac-arrest patients, and MEdical treatment in Idiopathic Ventricular Fibrillation patients
    Medical condition: Unexplained cardiac arrest patients after thorough investigations (Idiopathic ventricular fibrillation, IVF)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-002998-11 Sponsor Protocol Number: ENDO-RCA Start Date*: 2014-11-14
    Sponsor Name:Rigshospitalet, Capital Region Bloodbank 2034, Section for Transfusion Medicine
    Full Title: Safety and efficacy of low-dose Iloprost administration and blood pressure target in addition to standard therapy, as compared to standard therapy alone, in post-cardiac- arrest-syndrome patients...
    Medical condition: Cardiac Arrest
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004849 10007517 Cardiac arrest transient LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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