Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Cerebral edema

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    37 result(s) found for: Cerebral edema. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2009-010756-10 Sponsor Protocol Number: Index-CSBTE-01-09 Start Date*: 2009-05-19
    Sponsor Name:InDex Pharmaceuticals AB
    Full Title: Effect of an additional single dose of Kappaproct to corticosteroid treated patients with brain edema caused by brain tumor
    Medical condition: Patients with increasing clinical symptoms of brain edema caused by brain tumor or brain metatstasis, on maximum dose of corticosteroids will be asked to participate in the study. The brain edema m...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006121 Brain edema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-006694-39 Sponsor Protocol Number: ASF-CP02-001 Start Date*: 2022-07-08
    Sponsor Name:Lantmännen Medical AB
    Full Title: An open-label, historical cohort control study to evaluate the safety and tolerability of AF-16 in patients with cerebral oedema caused by traumatic brain injury (TBI)
    Medical condition: Cerebral oedema caused by traumatic brain injury (TBI)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    20.1 100000004852 10008127 Cerebral oedema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004854-41 Sponsor Protocol Number: 252LH301 Start Date*: 2018-11-09
    Sponsor Name:Biogen Idec Research Limited
    Full Title: Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema followi...
    Medical condition: Cerebral edema following Large Hemispheric Infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10008107 Cerebral edema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) CZ (Completed) DK (Prematurely Ended) BE (Completed) PT (Prematurely Ended) ES (Prematurely Ended) HU (Completed) FI (Completed) LT (Completed) IT (Prematurely Ended) HR (Completed)
    Trial results: View results
    EudraCT Number: 2009-011696-68 Sponsor Protocol Number: 09014 Start Date*: 2009-10-09
    Sponsor Name:University of Nottingham
    Full Title: The effect of drugs used to reverse neuromuscular blockade on intra-cranial pressure
    Medical condition: intracranial pressure changes following craniotomy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050598 Brain operation NOS LLT
    9.1 10058952 Brain swelling LLT
    9.1 10061019 Brain neoplasm LLT
    9.1 10061030 Brain tumour LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-000197-53 Sponsor Protocol Number: 2011-000197-53 Start Date*: 2011-04-15
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: Effects of Potassium Sparing Diuretics on Potassium Urinary Output, Plasma Levels and Cardiac Arrhythmias in Neurocritical Care Patients Receiving Mannitol Therapy for Cerebral Edema: double blind,...
    Medical condition: Acute Cerebral Edema
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10057359 Cerebellar edema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002076-39 Sponsor Protocol Number: WC42759 Start Date*: 2022-02-25
    Sponsor Name:Roche Farma S. A. U. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
    Full Title: A PHASE II, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE SAFETY AND EFFICACY OF BALOVAPTAN IN PATIENTS WITH ACUTE ISCHEMIC STROKE AT HIGH RISK OF DEVELOPING MALIG...
    Medical condition: Acute Ischemic Stroke (AIS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10008107 Cerebral edema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) FR (Completed)
    Trial results: View results
    EudraCT Number: 2004-004202-24 Sponsor Protocol Number: F7ICH-1641 Start Date*: 2005-04-29
    Sponsor Name:Novo Nordisk A/S
    Full Title: Randomised, Double-Blind, Placebo Controlled, Multi-Centre, Parallel Groups Confirmatory Efficacy and Safety Trial of Activated Recombinant Factor VII (NovoSeven®/Niastase®) in Acute Intracerebral ...
    Medical condition: Acute Intracerebral Haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    7.1 10022753 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed) SE (Completed) NO (Completed) DK (Completed) IT (Completed) BE (Completed) AT (Completed) GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-000230-53 Sponsor Protocol Number: TMC-CLV-07-02 Start Date*: 2008-05-15
    Sponsor Name:The Medicines Company
    Full Title: The evaluation of patients with acute hypertension and intracerebral hemorrhage with intravenous clevidipine treatment
    Medical condition: Acute hypertension in patients who present with intracerebral hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022754 Intracerebral hemorrhage LLT
    9.1 10020772 Hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006731-31 Sponsor Protocol Number: tandem-1 Start Date*: 2008-05-19
    Sponsor Name:Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol
    Full Title: Estudio doble ciego, aleatorizado, controlado con placebo de dosis escaladas de deferoxamina intravenosa en pacientes con ictus isquémico agudo tratado con activador tisular del plasminógeno. Doubl...
    Medical condition: La deferoxamina es un neuroprotector en modelos animales de isquemia/reperfusión cerebral. Si la deferoxamina es segura y bien tolerada en pacientes con ictus agudo puede significar una nueva estra...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027580 Middle cerebral artery stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002078-71 Sponsor Protocol Number: 16758 Start Date*: 2010-06-02
    Sponsor Name:Wilhelmina Children's Hospital/UMC Utrecht
    Full Title: Reductie van Hersenschade na “Perinatal Arterial Stroke”of PAS met recombinant humaan Erythropoietine (rhEPO): Een “Proof of Concept” en “Safety” studie
    Medical condition: treatment of perinatal stroke.
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-002095-17 Sponsor Protocol Number: MAGSPET Start Date*: 2011-09-13
    Sponsor Name:Anna Suy Franch
    Full Title: Sulfato de magnesio en pauta continua versus discontinua en la conducta expectante de la preeclampsia grave: ensayo clínico aleatorizado
    Medical condition: Preeclampsia grave
    Disease: Version SOC Term Classification Code Term Level
    14.0 10036585 - Pregnancy, puerperium and perinatal conditions 10040445 Severe pre-eclampsia, antepartum LLT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-001996-13 Sponsor Protocol Number: Tirofiban-Urokinasi 2007 Start Date*: 2007-06-06
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: Intravenous glycoprotein IIbIIIa inhibitor (Tirofiban) combined with low dose of intra-arterial Urokinase for the endovascolar treatment of patients with acute major ischemic stroke
    Medical condition: patients with major ischemic stroke not suitable for other authorized treatment for riperfusion of the ischemic area
    Disease: Version SOC Term Classification Code Term Level
    6.1 10057613 PT
    Population Age: In utero, Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003858-24 Sponsor Protocol Number: 252BN201 Start Date*: 2019-08-13
    Sponsor Name:Biogen Idec Research Limited
    Full Title: A Multicenter, Double-Blind, Multidose, Placebo-Controlled, Randomized, Parallel-Group, Phase 2 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 for Patients with Brain Contusion
    Medical condition: Brain contusion
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10052346 Brain contusion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005811-34 Sponsor Protocol Number: 24d005 Start Date*: 2018-07-05
    Sponsor Name:VU Medical Center, Amsterdam
    Full Title: Pregnancy reLated Acute hyperTension INtervention Action: a randomized trial comparing labetalol and nicardipine in women with acute hypertension in pregnancy (Platina-trial)
    Medical condition: To asses optimal treatment of hypertension of hypertensive disorders in pregnancy
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004890-15 Sponsor Protocol Number: EU-C-001-II-01 Start Date*: 2019-06-05
    Sponsor Name:Eustralis Pharmaceuticals Ltd.
    Full Title: A double-blind placebo-controlled study with an open-label pilot phase, assessing the efficacy, tolerability and safety of EU-C-001 in patients with moderate to severe traumatic brain injury
    Medical condition: Traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    22.1 100000004852 10021665 Increased intracranial pressure LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-006997-27 Sponsor Protocol Number: CRAD001M2301 Start Date*: 2011-06-01
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, double-blind, placebo-controlled study of RAD001 in the treatment of patients with subependymal giant cell astrocytomas (SEGA) associated with Tuberous Sclerosis Complex (TSC)
    Medical condition: This study will evaluate the antitumor activity of RAD001 versus placebo in patients with subependymal giant cell astrocytomas (SEGA) associated with Tuberous Sclerosis Complex (TSC).
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) IT (Completed) GB (Completed) DE (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-022583-13 Sponsor Protocol Number: CRAD001MIC02 Start Date*: Information not available in EudraCT
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An open-label, multi-center, expanded access study of RAD001 in patients with subependymal giant cell astrocytomas (SEGA) associated with tuberous sclerosis complex (TSC). The EFFECTS STUDY: Everol...
    Medical condition: The study will evaluate the safety of RAD001 in patients with subependymal giant cell astrocytomas (SEGA) associated with Tuberous Sclerosis Complex (TSC).
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) HU (Completed) CZ (Completed) FR (Ongoing) BE (Completed) GR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004217-18 Sponsor Protocol Number: glutamine 001 Start Date*: 2007-02-06
    Sponsor Name:Leiden University Medical Center
    Full Title: The Impact of glutamine suppletion on outcome in patients undergoing high-risk cardiothoracic surgery.
    Medical condition: Infectious complications after high-risk cardiothoracic surgery.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10051284 Parenteral nutrition LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015080-13 Sponsor Protocol Number: 3133K1-3003-WW Start Date*: 2010-01-22
    Sponsor Name:Wyeth Research Division of Wyeth Pharmaceuticals Inc., Clinical Research and Development
    Full Title: A Phase 3 Extension, Multicenter, Long-term Safety and Tolerability Trial of Bapineuzumab (AAB-001, ELN115727) in Subjects With Alzheimer Disease Who Are Apolipoprotein E ε4 Carriers and Participat...
    Medical condition: Alzheimer Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012271 Dementia Alzheimer's type PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Prematurely Ended) BE (Prematurely Ended) ES (Prematurely Ended) PT (Prematurely Ended) SK (Prematurely Ended) IT (Prematurely Ended) FI (Prematurely Ended) NL (Prematurely Ended) SE (Prematurely Ended) AT (Prematurely Ended) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015079-29 Sponsor Protocol Number: 3133K1-3002-WW Start Date*: 2010-01-22
    Sponsor Name:Wyeth Research Division of Wyeth Pharmaceuticals Inc., Clinical Research and Development
    Full Title: A Phase 3 Extension, Multicenter, Double-blind, Parallel-Group, Long-term Safety and Tolerability Trial of Bapineuzumab (AAB-001, ELN115727) in Subjects With Alzheimer Disease Who Are Apolipoprotei...
    Medical condition: Alzheimer Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012271 Dementia Alzheimer's type PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Prematurely Ended) BE (Prematurely Ended) ES (Prematurely Ended) PT (Prematurely Ended) SK (Prematurely Ended) IT (Prematurely Ended) FI (Prematurely Ended) NL (Prematurely Ended) SE (Prematurely Ended) AT (Prematurely Ended) DE (Prematurely Ended)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Sat May 10 21:33:30 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA