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Clinical trials for Contractility

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    44 result(s) found for: Contractility. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2012-001898-90 Sponsor Protocol Number: Crijns01.12-02-026 Start Date*: 2012-06-25
    Sponsor Name:Maastricht University Medical Center
    Full Title: Effects of vernakalant and flecainide on atrial contractility in patients with atrial fibrillation
    Medical condition: Patients with paroxysmal or persistent atrial fibrillation (AF) reporting at the first heart aid.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004650-93 Sponsor Protocol Number: botuline5 Start Date*: 2007-10-10
    Sponsor Name:University Medical Center Groningen
    Full Title: The effect of Botulinum toxin A injections for overactive bladder on detrusor contractility
    Medical condition: Neurogenic or idiopathic overactive bladder, not adequately responding to anticholinergic therapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059617 Overactive bladder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000460-90 Sponsor Protocol Number: AGO/2006/002 Start Date*: 2006-03-09
    Sponsor Name:University Hospital Ghent
    Full Title: Echocardiographic study of the haemodynamic effects of remifentanil with and without glycopyrrolate in healthy children
    Medical condition: ASA I and II children
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-005371-40 Sponsor Protocol Number: JP2-171560 Start Date*: 2014-11-17
    Sponsor Name:Szpital im. Jana Pawla II
    Full Title: Medical laser and stem cells in treatment ischemic heart disease
    Medical condition: Ischemic heart disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002187-26 Sponsor Protocol Number: neostigmine2019 Start Date*: 2019-08-28
    Sponsor Name:KU Leuven - TARGID
    Full Title: A Prospective evaluation of the effect of a single dose of neostigmine in patients with patients with weak or absent esophageal peristalsis
    Medical condition: Patients with complaints of dysphagia and poor esophageal motility
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006660-30 Sponsor Protocol Number: RO730 Start Date*: 2009-03-11
    Sponsor Name:Hull and East Yorkshire Hospitals NHS Trust
    Full Title: Contemporary Heart Failure Management : A Randomised, Placebo-Controlled Trial to Measure the Effects of Low Dose Digoxin on Haemodynamics and Symptoms in Patients with Heart Failure
    Medical condition: Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003906-89 Sponsor Protocol Number: 2163/2006 Start Date*: 2006-11-23
    Sponsor Name:Istituto Fisiologia Clinica, CNR
    Full Title: Insulin Therapy in non-diabetic patients with Acute Coronary Syndromes: Effect of strict glycemic control on systemic endothelial function, coronary flow reserve, and left ventricular contractility
    Medical condition: Iperglycemia with Acute Coronary Syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051592 Acute coronary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-004034-41 Sponsor Protocol Number: 21267983 Start Date*: 2005-11-25
    Sponsor Name:Genzyme Europe B.V.
    Full Title: Evaluation of Skeletal Myoblast Transplant for Treating Ischemic Heart Failure Phase 2 Study Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) Study
    Medical condition: Ischemic Heart Failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-002645-38 Sponsor Protocol Number: BIOMARCHA Start Date*: 2012-09-04
    Sponsor Name:CRESIB-Barcelona Centre for International Health Research
    Full Title: Evolution of serologic biomarkers and diastolic function and segmentary contractility determined by echocardiography after treatment in Chagas diseases
    Medical condition: The study will be held in 63 patients with chronic Chagas Disease and 63 healthy people
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006081-29 Sponsor Protocol Number: Rimonaslok Start Date*: 2008-10-21
    Sponsor Name:UZLeuven
    Full Title: INFLUENCE OF RIMONABANT ON LOWER ESOPHAGEAL FUNCTION IN HEALTHY VOLUNTEERS
    Medical condition: none; this is a physiological study to investigate the influence of CB1 receptor antagonism by rimonabant (normally used for the treatment of obesity) on esophageal function, i.e. esophageal contr...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017924 Gastroesophageal reflux LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000867-27 Sponsor Protocol Number: HDPET Start Date*: 2006-05-04
    Sponsor Name:University Medical Center Groningen
    Full Title: Gated 13N-NH3 PET before and during hemodialysis for the assessment of changes in myocardial perfusion, volumes and output of the left ventricle
    Medical condition: Hemodialysis patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015826-13 Sponsor Protocol Number: Q-10 Start Date*: 2010-10-07
    Sponsor Name:PROF. TIZIANO GHERLI
    Full Title: THE USE OF COENZYME Q 10 BEFORE HEART SURGERY IN ELDERLY PATIENTS.
    Medical condition: Patients (male or female) aged > 70 years, clinically stable, with a diagnosis of severe aortic stenosis with indication to surgery based on echocardiography and left ventricle angiography.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10049194 Stable angina pectoris LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-004082-33 Sponsor Protocol Number: erythstom2 Start Date*: 2011-10-05
    Sponsor Name:UZLeuven
    Full Title: The role of induced phase 3 contractions in the control of hunger and food intake
    Medical condition: Gastrointestinal contractility will be studied in healthy volunteers for 7 hours in a fasting condition
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2012-004600-35 Sponsor Protocol Number: Modifast3 Start Date*: 2012-12-19
    Sponsor Name:KULeuven
    Full Title: Effect of diet-induced weight loss on motilin, ghrelin, bitter taste perception, hunger and the migrating motor complex: a prospective study
    Medical condition: Gastrointestinal contractility and hormones will be studied in obese patients before and after weight loss induced by a diet
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002278-37 Sponsor Protocol Number: panto001 Start Date*: 2008-08-12
    Sponsor Name:Johann Wolfgang Goethe Universität
    Full Title: Auswirkungen von Pantoprazol auf die myokardiale Kontraktilität bei Patienten mit Herzinsuffizienz - influence of pantoprazole on human myocardial contractility at patients with congestive heart fa...
    Medical condition: Recently literature revealed facts, that show H+/K+ ATPase expression is not limited tot he stomach. H+/K+ ATPase was also found in smooth muscle cells and in other tissues (McCabe, R.D. et al., Am...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004979-39 Sponsor Protocol Number: 8.1 Start Date*: 2014-12-19
    Sponsor Name:VieCuri Medical Center
    Full Title: Levosimendan in Acute Kidney Injury Study, a prospective, randomized, monocenter, double blind, placebo-controlled study to investigate the efficacy and safety of Levosimendan in Intensive Care Pat...
    Medical condition: Acute Kidney Injury (AKI) in adult ICU patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004012-31 Sponsor Protocol Number: RD 5130-009-07 Start Date*: 2009-07-06
    Sponsor Name:Derby Hospitals NHS Foundation Trust [...]
    1. Derby Hospitals NHS Foundation Trust
    2. The University of Nottingham-Research innovation services
    Full Title: The effects of improving oxygen concentration in the reduction of dialysis induced myocardial stunning – A pilot study
    Medical condition: Chronic renal failure patients who are receiving haemodialysis treatment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066623 Chronic haemodialysis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005435-98 Sponsor Protocol Number: version_2.0_dated_19.04.2011 Start Date*: 2012-06-21
    Sponsor Name:Śląski Uniwersytet Medyczny w Katowicach
    Full Title: A randomized, prospective, double-blind study with placebo to evaluate the efficacy of treatment of patients with angina resistant to pharmacological treatment and induced myocardial ischemia with...
    Medical condition: Stable angina pectoris CCS II-IV
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10049194 Stable angina pectoris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2004-001922-26 Sponsor Protocol Number: BMI-EU-02-008 Start Date*: 2006-01-06
    Sponsor Name:Bioheart, Inc
    Full Title: A Phase II, Open-label, Randomized, Multicenter Study to Assess the Safety and Cardiovascular Effects of MyoCell™ Implantation by a Catheter Delivery System in Congestive Heart Failure Patients Pos...
    Medical condition: Patients with congestive heart failure who have had a previous myocardial infarction.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004723-17 Sponsor Protocol Number: UZBSK001 Start Date*: 2021-02-26
    Sponsor Name:UZ Brussel
    Full Title: Clinical usefulness and influence on oesophageal motility of pyridostigmine for dysphagia in systemic sclerosis.
    Medical condition: Dysphagia by patients suffering from systemic sclerosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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