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Clinical trials for Cough AND Cough challenge test

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    45 result(s) found for: Cough AND Cough challenge test. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2014-000306-36 Sponsor Protocol Number: XEN-D0501-CL-04 Start Date*: 2014-05-20
    Sponsor Name:Xention Limited
    Full Title: A double-blind, randomised, placebo-controlled, crossover study to assess the efficacy of XEN D0501, a TRPV1 antagonist, in reducing the frequency of cough in patients with chronic idiopathic cough
    Medical condition: Chronic Idiopathic Cough
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004855 10066656 Chronic cough LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-003980-36 Sponsor Protocol Number: IIT15419 Start Date*: 2018-01-26
    Sponsor Name:Hull and East Yorkshire Hospitals NHS Trust
    Full Title: A single-Centre, open-label, exploratory study of the effect of 20 mg ambroxol hydrochloride on cough reflex sensitivity in patients with acute cough.
    Medical condition: acute cough assouciated with URTI
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10066522 Acute cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004589-14 Sponsor Protocol Number: BC1036-001 Start Date*: 2012-05-17
    Sponsor Name:Respicopea Limited
    Full Title: A Multicentre, Double-Blind, Placebo-Controlled, Adaptive Pivotal Study of the Efficacy and Safety of Oral BC1036 in the Management of Cough
    Medical condition: Chronic and sub acute persistent cough
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10066656 Chronic cough LLT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10070801 Persistent cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002034-47 Sponsor Protocol Number: AF219-014 Start Date*: 2015-10-12
    Sponsor Name:Afferent Pharmaceuticals, Inc.
    Full Title: A Study to Assess the Effect of AF-219 on Cough Reflex Sensitivity in Both Healthy and Chronic Cough Subjects
    Medical condition: Chronic cough
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-004891-20 Sponsor Protocol Number: PNV117270 Start Date*: 2013-09-06
    Sponsor Name:GlaxoSmithKline Research and Development Ltd
    Full Title: A randomised, double-blind (sponsor-unblind), placebo controlled, cross-over study to investigate the efficacy, effect on cough reflex sensitivity, safety, tolerability and pharmacokinetics of inha...
    Medical condition: chronic idiopathic cough
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-000464-34 Sponsor Protocol Number: AF219-015 Start Date*: 2015-04-29
    Sponsor Name:Afferent Pharmaceuticals, Inc.
    Full Title: A Study to Assess the Effect of AF-219 on Cough Reflex Sensitivity in Both Healthy and Chronic Cough Subjects
    Medical condition: Chronic Cough
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002165-39 Sponsor Protocol Number: P04887 Start Date*: 2006-11-30
    Sponsor Name:Schering Plough Research Institute, a division of Schering Corporation
    Full Title: Study of the Efficacy and Safety of SCH486757 in Subjects With Chronic Idiopathic Cough
    Medical condition: Chronic Idiopathic Cough
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002164-26 Sponsor Protocol Number: P04888 Start Date*: 2006-11-10
    Sponsor Name:Schering Plough Research Institute, a division of Schering Corporation
    Full Title: Study of the Efficacy and Safety of SCH619734 in Subjects with Chronic Idiopathic Cough
    Medical condition: Chronic Idiopathic Cough
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004102-13 Sponsor Protocol Number: AcadMed CTU210406 Start Date*: 2006-10-16
    Sponsor Name:Hull and east yorkshire Hospitals Trust
    Full Title: An 8 week, non-selected, cohort, study to investigate whether the treatment of reflux induced cough alters associated bronchial hyperresponsiveness.
    Medical condition: Bronchial hyper-responsiveness in relation to reflux associated chronic cough
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011233 Coughing and associated symptoms HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-000620-14 Sponsor Protocol Number: Cough/1/2010 Start Date*: 2011-12-22
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA CAREGGI
    Full Title: Effects of short term Erdosteine treatment on chronic cough on bronchitis phenotypes of COPD
    Medical condition: COPD
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10038738 Respiratory, thoracic and mediastinal disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004748-27 Sponsor Protocol Number: Acadmed CTU01/05 Start Date*: 2005-02-21
    Sponsor Name:Hull and east Yorkshire Hospitals Trust, Research and Deveopment, admin porta cabin
    Full Title: An 8 week, double-blind, randomised, parallel group study to investigate the effect of 20 mg Esomeprazole (Nexium) tablets Twice daily versus placebo on symptoms associated with chronic cough due ...
    Medical condition: We will be using Nexium to treat gastro-oesophageal reflux and in return this will reduce reflux related cough ( a manifestation of reflux)
    Disease: Version SOC Term Classification Code Term Level
    3 10013946 2
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-021642-22 Sponsor Protocol Number: VR1114693 Start Date*: 2011-04-01
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A two part study to investigate the pharmacokinetics and pharmacodynamics of SB705498, a TRPV1 antagonist, in cough. Part A: an open label study in healthy subjects to determine the exposure to SB-...
    Medical condition: Chronic cough
    Disease: Version SOC Term Classification Code Term Level
    14.0 10038738 - Respiratory, thoracic and mediastinal disorders 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-004041-17 Sponsor Protocol Number: XEN-D0501-CL-05 Start Date*: 2013-12-13
    Sponsor Name:Xention Limited
    Full Title: A double-blind, randomised, placebo-controlled, crossover study to assess the efficacy of XEN-D0501, a TRPV1 antagonist, in reducing the frequency of cough in patients with chronic obstructive pulm...
    Medical condition: Chronic Obstructive Pulmonary Disease.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004855 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-004095-37 Sponsor Protocol Number: CQAB149A2222 Start Date*: 2005-02-25
    Sponsor Name:Novartis Pharma Services
    Full Title: An exploratory, multi-center, randomized, open-label, single dose, crossover study to assess the safety and tolerability of 200µg of QAB149, delivered via a MDDPI, with or without the co-administra...
    Medical condition: 1) Stable persistent asthma 2) COPD
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) BE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-003194-33 Sponsor Protocol Number: VAC18193RSV2002 Start Date*: 2017-10-03
    Sponsor Name:Janssen Vaccines and Prevention B.V.
    Full Title: An Exploratory, Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the prophylactic Efficacy of a Single Immunization of Ad26.RSV.preF Against Respiratory Syncytial Virus Infe...
    Medical condition: Prophylactic respiratory syncytial virus (RSV) vaccine.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-003653-26 Sponsor Protocol Number: OVG2011/07 Start Date*: 2011-12-08
    Sponsor Name:Clinical Trials and Research Governance
    Full Title: A phase II, single-centre, randomised, single-blind, study to evaluate Vi-CRM197 against historical unvaccinated controls in a healthy adult challenge model, with a Vi-PS vaccine control arm.
    Medical condition: Prophylaxis for Salmonella enterica serovar Typhi (S. Typhi) disease
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10039446 Salmonella typhi infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005838-12 Sponsor Protocol Number: OC000459/004/05 Start Date*: 2006-03-30
    Sponsor Name:Oxagen Ltd
    Full Title: A PHASE II STUDY OF THE EFFICACY (AS ASSESSED BY BRONCHIAL ALLERGEN CHALLENGE) AND SAFETY OF OC000459 DOSED ORALLY (200mg BID WITH FOOD) IN SUBJECTS WITH ALLERGIC ASTHMA; IN A RANDOMISED, DOUBLE BL...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-004612-22 Sponsor Protocol Number: FP-01.1_CS_04 Start Date*: 2013-12-24
    Sponsor Name:Immune Targeting Systems Ltd
    Full Title: A randomised, double-blind, placebo-controlled study to assess the safety, tolerability, efficacy and immunogenicity of an influenza A vaccine (Vaccine FP-01.1) in healthy volunteers following viru...
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004862 10022002 Influenza A virus infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-002847-62 Sponsor Protocol Number: TCS_19_02 Start Date*: 2020-05-28
    Sponsor Name:Marinomed Biotech AG
    Full Title: Clinical evaluation of two different dosage groups of Tacrosolv over 8 days with once daily administration in a placebo controlled cross-over design to evaluate safety and efficacy in patients suff...
    Medical condition: Allergic rhinoconjunctivitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10001728 Allergic rhinoconjunctivitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003795-35 Sponsor Protocol Number: Griac001 Start Date*: 2006-10-03
    Sponsor Name:University Medical Center Groningen
    Full Title: Mannitol inhalations as a faster procedure for testing of airways hyperresponsiveness
    Medical condition: Detection of airway hyperresponsiveness in patients with asthma or COPD
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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