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Clinical trials for Cruciate ligament

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    19 result(s) found for: Cruciate ligament. Displaying page 1 of 1.
    EudraCT Number: 2007-007668-15 Sponsor Protocol Number: AGO/2007/016 Start Date*: 2008-03-10
    Sponsor Name:University Hospital Ghent
    Full Title: Evaluatie van Arthroscopisch Voorste Kruisband Herstel via Ziekenhuisopname of via Dagopname: een Gerandomiseerde Prospectieve Klinische Studie.
    Medical condition: Patients who suffered from a isolated rupture of the Anterior Cruciate Ligament with instability of the knee joint
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059062 Anterior cruciate ligament tear LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002732-75 Sponsor Protocol Number: MSC-ACLrep Start Date*: 2021-02-01
    Sponsor Name:Alexander IV sp. Partnership Ortopedika Surgery Specialistic Center
    Full Title: The use of mesenchymal stem cells from the bone marrow stroma for reconstruction of the anterior cruciate ligament
    Medical condition: Rupture of the anterior cruciate ligament in the knee
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10049548 Knee operation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001708-31 Sponsor Protocol Number: Protokol_PPB_ACL_21042017 Start Date*: 2017-06-20
    Sponsor Name:Aarhus University Hospital
    Full Title: The effect of the popliteal plexus block on postoperative pain after reconstruction of the anterior cruciate ligament
    Medical condition: Postoperative pain after reconstruction of the anterior cruciate ligament
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000021343 10078191 Anterior cruciate ligament reconstruction LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-000663-83 Sponsor Protocol Number: SM3-ME-13 Start Date*: 2013-04-19
    Sponsor Name:Rigshospitalet
    Full Title: The effect of Adductor-Channel Blockade with high pain responders after reconstruction of the anterior cruciate ligament
    Medical condition: Patients who will undergo reconstruktion of ligament cruciate ligament.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003684-54 Sponsor Protocol Number: ACLS Start Date*: 2014-03-27
    Sponsor Name:Academic Medical Center Amsterdam
    Full Title: Analgesic efficacy of saphenous nerve blockade for outpatient knee anterior cruciate ligament surgery
    Medical condition: Mid thigh saphenous nerve block with levobupivacain, as compared to femoral nerve block, in patients undergoing anterior cruciate ligament surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001556-12 Sponsor Protocol Number: RD-5103-024-05 Start Date*: 2006-08-17
    Sponsor Name:Derby Hospitals NHS Foundation Trust
    Full Title: Hamstrings Graft Donor Site Infiltration with Bupivacaine for Pain Relief after Arthroscopically Assisted Anterior Cruciate Ligament Reconstruction
    Medical condition: Anterior Cruciate Ligament Reconstruction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002731-24 Sponsor Protocol Number: UAort/06/001 Start Date*: 2006-07-12
    Sponsor Name:University of Aberdeen
    Full Title: The use of morphine in addition to local anaesthetic for post operative analgesia in anterior cruciate reconstruction
    Medical condition: Rupture of anterior cruciate ligament being corrected by anterior cruciate reconstruction.
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-002712-30 Sponsor Protocol Number: FPS-SMG-2021-02 Start Date*: 2021-10-05
    Sponsor Name:FUNDACIÓN PÚBLICA ANDALUZA PROGRESO Y SALUD
    Full Title: PHASE III, RANDOMISED, DOUBLE-BLIND, CLINICAL TRIAL TO DETERMINE THE ROLE OF MAGNESIUM SULPHATE IN ADDUCTOR CANAL BLOCK IN ARTHROSCOPIC KNEE SURGERY
    Medical condition: Pain in arthroscopic anterior cruciate ligament reconstruction surgery.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000299-25 Sponsor Protocol Number: 1.4 Start Date*: 2014-12-05
    Sponsor Name:Unfallkrankenhaus Salzburg
    Full Title: Dexmedetomidine for saphenous nerve blockade in patients undergoing anterior cruciate ligament replacement: a randomized, placebo-controlled, triple blinded study
    Medical condition: Dexmedetomidine -a selective alpha-2-receptor agonist- added to a local anaesthetic (ropivacaine) should prolong a saphenous block and the patients demand for the first analgesic. We designed a pro...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001782-18 Sponsor Protocol Number: MRZ 92579-0404/1 Start Date*: 2005-02-14
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: Saftey and efficacy of two different doses of Neramexane mesylate as preemptive analgesic and add-on therapy to opioids in the management of postoperative pain. A randomised, double-blind, placebo-...
    Medical condition: Moderate to severe acute postoperative pain
    Disease: Version SOC Term Classification Code Term Level
    7.1 10054711 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2020-005742-42 Sponsor Protocol Number: SCALA Start Date*: 2023-04-13
    Sponsor Name:Groupement de Coopération Sanitaire Ramsay Générale de Santé pour l’Enseignement et la Recherche
    Full Title: Effect of botulinum toxin on hamstring contracture and the occurrence of cyclops syndrome after anterior cruciate ligament reconstruction
    Medical condition: Cyclops syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10058029 Arthrofibrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022500-50 Sponsor Protocol Number: 2602-967 Start Date*: 2010-10-19
    Sponsor Name:Ortopædkirurgisk afdeling
    Full Title: Pain treatment after anterior cruciate ligament reconstruction - Comparison of infiltration analgesia with femoral nerve block after hamstrings anterior cruciate ligament reconstruction.
    Medical condition: Smertebehandling i forbindelse med rekonstruktionsoperation af forreste korsbånds
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002192 Analgesic drug level NOS therapeutic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-019517-16 Sponsor Protocol Number: SM1-MET-10 Start Date*: 2010-05-19
    Sponsor Name:Professor Jørgen B. Dahl
    Full Title: Effekten af Adductor-Kanal-Blokade (AKB) på patienter efter rekonstruktion af forreste korsbånd (ACL) i dagkirurgisk regi (The Effect of Adductor-Channel Blockade (ACB) in Patients After Anterior...
    Medical condition: Patients who have had a Reconstruction of the Anterior Cruciate Ligament. We want to investigate wheater Ropivacain can be used as a postoperative analgetic drug, when applied ultrasound-guided as...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10036236 Postoperative pain relief LLT
    12.1 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001056-22 Sponsor Protocol Number: NDOL-001-2016 Start Date*: 2016-08-24
    Sponsor Name:Medical Univerity Vienna
    Full Title: Neodolpasse® Infusion Solution versus diclofenac 75 mg infusion in the treatment of postoperative pain after elective knee surgery - an exploratory placebo-controlled clinical study to investigate ...
    Medical condition: major elective knee surgery (cruciate ligament surgery)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-024162-22 Sponsor Protocol Number: ACTLP001-01 Start Date*: 2012-05-02
    Sponsor Name:Azellon Ltd
    Full Title: A Prospective Open-Label Study to Evaluate the Safety of Cell Bandage (Mesenchymal Stem Cells) in the Treatment of Meniscal Tears
    Medical condition: Meniscal tear that would otherwise be treated by a partial meniscectomy.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2006-004817-16 Sponsor Protocol Number: MACI00206 Start Date*: 2008-01-23
    Sponsor Name:Genzyme Europe B.V.
    Full Title: A Prospective, Randomized, Open-Label, Parallel-Group, Multicenter Study to Demonstrate the Superiority of Matrix-induced Autologous Chondrocyte Implantation (MACI® implant) versus Arthroscopic Mi...
    Medical condition: Symptomatic Articular Cartilage Defects of the Femoral Condyle including the Trochlea. osteochondritis dissecans lesions that do not require a bone graft.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10031231 Osteochondritis dissecans LLT
    13.1 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) SE (Completed) NL (Completed) PL (Completed) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004921-33 Sponsor Protocol Number: R475-OA-1758 Start Date*: 2018-11-09
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients with Pain Due to Osteoarthritis of the Hip or Knee
    Medical condition: Pain due to osteoarthritis of the hip or knee
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) PL (Completed)
    Trial results: View results
    EudraCT Number: 2017-002601-35 Sponsor Protocol Number: ACT-2017-01 Start Date*: 2018-07-02
    Sponsor Name:PrimeCell Advanced Therapy a.s.
    Full Title: A Prospective, Randomized, Controlled, Multicenter, Phase II / III, Clinical Study to Evaluate the Effectiveness and Safety of NTC chondrograft® versus the Standard Procedure Arthroscopic Microfrac...
    Medical condition: Symptomatic knee articular cartilage defects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001702-15 Sponsor Protocol Number: R475-OA-1688 Start Date*: 2018-03-05
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: A Phase 3 Randomized, Double-Blind, Multi-Dose, Placebo And NSAID-Controlled Study To Evaluate The Efficacy And Safety Of Fasinumab In Patients With Pain Due To Osteoarthritis Of The Knee Or Hip
    Medical condition: Pain due to osteoarthritis of the knee or hip
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) DE (Completed) EE (Completed) GB (GB - no longer in EU/EEA) RO (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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