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Clinical trials for Dental caries

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    18 result(s) found for: Dental caries. Displaying page 1 of 1.
    EudraCT Number: 2009-010725-39 Sponsor Protocol Number: 56493 Start Date*: 2009-07-23
    Sponsor Name:The University of Manchester [...]
    1. The University of Manchester
    2. Belfast Health and Social Care Trust
    Full Title: A randomised controlled trial to measure the effects and costs of a dental caries prevention regime for young children attending primary care dental services
    Medical condition: Dental Caries
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10012318 Dental caries PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-002402-13 Sponsor Protocol Number: R04684 Start Date*: 2018-02-02
    Sponsor Name:Manchester University NHS Foundation Trust
    Full Title: A Randomised controlled trial to Evaluate the effectiveness and cost benefit of prescribing high dose FLuoride toothpaste in preventing and treating dEntal Caries in high-risk older adulTs (REFLECT...
    Medical condition: Dental caries in high-risk older adults
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10012318 Dental caries PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-023476-23 Sponsor Protocol Number: SPON766-09 Start Date*: 2011-03-17
    Sponsor Name:Cardiff University
    Full Title: Seal or Varnish? A Randomised Trial To Determine The Relative Cost And Effectiveness Of Pit And Fissure Sealants And Fluoride Varnish In Preventing Dental Decay
    Medical condition: Dental Caries
    Disease: Version SOC Term Classification Code Term Level
    13.1 10012318 Dental Caries LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-002287-26 Sponsor Protocol Number: GN12CO201 Start Date*: 2012-10-24
    Sponsor Name:Greater Glasgow and Clyde NHS Board [...]
    1. Greater Glasgow and Clyde NHS Board
    2. University of Glasgow
    Full Title: Comparison of the caries-protective effect of fluoride varnish (Duraphat®) with treatment as usual in nursery school attenders receiving preventive oral health support through the Childsmile Progra...
    Medical condition: Childhood dental caries
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10012318 Dental caries PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005742-37 Sponsor Protocol Number: 06/AN/02 Start Date*: 2007-01-26
    Sponsor Name:NHS Glasgow and Clyde / University of Glasgow
    Full Title: Randomised clinical trial of the effects of total intravenous anaesthesia (TIVA: propofol) versus volatile anaesthesia (sevoflurane-N20 induction and isoflurane-N20 maintenance) on children’s post...
    Medical condition: Dental caries
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012318 Dental caries LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-006537-14 Sponsor Protocol Number: 2-geltest Start Date*: 2008-05-05
    Sponsor Name:Sven-Åke Lundin
    Full Title: 2-geltest: Comparison of plaque-inhibiting efect of toothbrushing with Sodium Fluoride el 0,2 % and Sodium Fluoride.Chlorhexidine Gel 0,2 % + 0,2 % respectively, in treatment of initial and manifes...
    Medical condition: Children aged 1-3 yearsr with initial and/or manifest caries on buccal surfaces of their upper incisors
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006104-11 Sponsor Protocol Number: CHX2007-01 Start Date*: 2008-12-23
    Sponsor Name:CHX Technologies Europe Ltd.
    Full Title: Phase IV Open-label Pharmaco-economic and Practice Management Study of a New Preventive Treatment for Adult Caries in the U.K. and Germany
    Medical condition: Adult dental caries
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-002982-30 Sponsor Protocol Number: AGO/2008/004 Start Date*: 2008-10-09
    Sponsor Name:University Hospital Ghent
    Full Title: A Prospective, randomized, clinical study on the effects of CPP-ACP paste on plaque, gingivitis and initial caries lesion development in orthodontic patients - part 2
    Medical condition: Plaque and the initial development of caries and gingivitis in orthodontic patients.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003845-15 Sponsor Protocol Number: PHI/03/C1/017 Start Date*: 2005-12-13
    Sponsor Name:University of Manchester
    Full Title: A cluster randomised control trial to measure the benefit of fluoride varnish in preventing dental decay when applied to the permanent teeth of children for three years in the school setting
    Medical condition: Dental caries in first permanent molars
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-005300-29 Sponsor Protocol Number: SDF1 Start Date*: 2016-06-06
    Sponsor Name:Malmö University, Faculty of Odontology
    Full Title: Prevention and treatment of initial rotcaries among elderly in Skåne.
    Medical condition: Dental caries
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004711-23 Sponsor Protocol Number: DT11/9936 Start Date*: 2013-05-22
    Sponsor Name:Leeds Dental Institute
    Full Title: Comparative studies of the anaesthetic efficacy of 4% Articaine used as mandibular infiltration versus 2% Lidocaine used as inferior dental nerve block, in extraction and pulpotomy of mandibular pr...
    Medical condition: Dental caries in primary molars
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000260-17 Sponsor Protocol Number: Intermed_Chlorhexidine_sol_0.2%_ Start Date*: 2012-09-07
    Sponsor Name:IOULIA & IRENE TSETI PHARMACEUTICAL LABORATORIES S.A.-INTERMED S.A.
    Full Title: A therapeutic equivalence study, comparing two chlorhexidine digluconate formulations, the test formulation Chlorel® Or. T. Sol. 0,2% w / v and the reference formulation Corsodyl® 0.2% w / v Mint M...
    Medical condition: Therapeutic equivalence study, comparing two chlorhexidine digluconate formulations indicated for inhibition of the formation of dental plaque, as an aid in the treatment and prevention of gingivi...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10042613 - Surgical and medical procedures 10063390 Oral hygiene LLT
    15.0 10017947 - Gastrointestinal disorders 10058078 Tooth plaque LLT
    15.0 10021881 - Infections and infestations 10018294 Gingivitis infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2010-020538-24 Sponsor Protocol Number: GASAS-1002X Start Date*: 2011-02-16
    Sponsor Name:GABA International AG
    Full Title: White spot lesion development in post-orthodontic patients following weekly application of a 1.25% fluoride gel compared to placebo over 6 months
    Medical condition: To monitor the white spot lesion development and dental status under weekly applied 1.25% fluoride gel compared to placebo in patients after orthodontic treatment with multibracket appliances
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002366-38 Sponsor Protocol Number: P305 R-EF02 Start Date*: 2004-11-16
    Sponsor Name:GABA GmbH
    Full Title: Fluoride uptake and remineralisation of incipient carious lesions following the application of fluoride fluids with different fluoride concentrations
    Medical condition: caries lesions
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-003240-20 Sponsor Protocol Number: 16-058 Start Date*: 2017-10-12
    Sponsor Name:RWTH Aachen, represented by the rector, himself represented by the dean of the Medical Faculty
    Full Title: Velphoro and impact on the oral cavity and gut microbiome
    Medical condition: Hyperphosphatemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001468-21 Sponsor Protocol Number: KIIOIW001 Start Date*: 2006-08-24
    Sponsor Name:Karolinska Institutet
    Full Title: Sympthomatic and prophylactic treatment of drug induced oral dryness in elderly patients with high drug consumption.
    Medical condition: Oral dryness is a common problem with serious consquences, especially among elderly individuals. The most common reason for oral dryness is drug consumption. Research has shown that an individual w...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000600-29 Sponsor Protocol Number: UX023-CL301 Start Date*: 2016-09-15
    Sponsor Name:Ultragenyx Pharmaceuticals Inc
    Full Title: A Randomized, Open-Label, Phase 3 Study to Assess the Efficacy and Safety of KRN23 Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients with X-linked Hypophosphatemia (XLH)
    Medical condition: X-linked hypophosphatemia (XLH) is a disorder of renal phosphate wasting, defective bone mineralisation, and impaired growth plate or endochondral ossification caused by inactivating mutations in t...
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004850 10016206 Familial hypophosphataemic rickets LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) IE (Completed) DE (Completed) ES (Prematurely Ended) SE (Completed) GB (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-001489-41 Sponsor Protocol Number: P00003466 Start Date*: 2018-07-02
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Radiation- and alkylator-free hematopoietic cell transplantation for bone marrow failure due to dyskeratosis congenita / telomere disease
    Medical condition: Dyskeratosis congenita / telomere disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10001756 Allogenic bone marrow transplantation therapy PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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