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Clinical trials for Design effect

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    302 result(s) found for: Design effect. Displaying page 1 of 16.
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    EudraCT Number: 2023-000126-29 Sponsor Protocol Number: SZÚ/00127/2023 Start Date*: 2023-04-21
    Sponsor Name:Státní zdravotní ústav
    Full Title: Pilot Study of Combined PDT and SDT Efficacy In Vivo in Human Volunteers for Application in Hygiene and Clinical Practice
    Medical condition: Antimicrobial efficacy of combined PDT and SDT on the skin
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001669-17 Sponsor Protocol Number: 18GS001 Start Date*: 2018-08-28
    Sponsor Name:Nottingham University Hospitals NHS Trust
    Full Title: ICaRAS (IV Iron for Cancer Related Anaemia Symptoms) – A Feasibility Study of Intravenous Iron Therapy for Anaemia in Palliative Cancer Care.
    Medical condition: Iron deficiency anaemia secondary to cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004851 10002062 Anaemia iron deficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-015799-92 Sponsor Protocol Number: FER-SURG02-Pilot Start Date*: 2009-12-02
    Sponsor Name:Universitätspital Zürich Anästhesie
    Full Title: Intravenous ferric carboxymaltose (Ferinject®) with or without Erythropoietin for the correction of preoperative anaemia in patients undergoing orthopaedic surgery
    Medical condition: • To evaluate the effect of the administration of ferric carboxymaltose (Ferinject®) with or without erythropoietin vs. no treatment (standard therapy) on the preoperative anaemia status in patient...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002968-10 Sponsor Protocol Number: 024 Start Date*: 2008-01-17
    Sponsor Name:Department of Medicine I, Clinical Dep. f. Oncology, University Hospital,
    Full Title: Treatment of Patients Suffering from Tumour Cachexia with Dronabinol (tetrahydrocannabinol) or Placebo Comparison of individually optimised dosages in a double blind, randomised parallel design
    Medical condition: tumour cachexia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-003648-59 Sponsor Protocol Number: CH1.0 Start Date*: 2012-10-01
    Sponsor Name:Dept. of Neurology, Atrium Medical Centre
    Full Title: Oxygen treatment for cluster headache attacks at different flow rates. A double-blind, randomized, cross-over design study.
    Medical condition: To study whether there is a difference in treatment effect between oxygen at flow rates of 7 L/min versus 12 L/min in the acute treatment of cluster headache attacks.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004071-34 Sponsor Protocol Number: PRG-Opioid-06-/03 Start Date*: 2009-01-14
    Sponsor Name:Queen Mary, University of London (QMUL)
    Full Title: A single centre, parallel group, pilot study to investigate the effect of opioids on immunomarkers using gene expression profiling.
    Medical condition: This study is not looking at any disease process
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002962-37 Sponsor Protocol Number: NA_00008675 Start Date*: 2010-09-14
    Sponsor Name:VU Medical Center Amsterdam
    Full Title: Phase I/II study of dalteparin, a low molecular weight heparin (LMWH), in combination with Sunitinib (SU11248), an oral, selective multitargeted tyrosine kinase inhibitor, as first line treatment, ...
    Medical condition: Patients with metastatic or inoperable renal cell cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016827-72 Sponsor Protocol Number: GAL-Moa-003 Start Date*: 2010-01-12
    Sponsor Name:Galenica AB
    Full Title: A multicentre, randomized, double-blind, safety and efficacy non-inferiority, intra-individual study, comparing Mometasone furoate Galenica 0.1% cream with Elocon 0.1% cream and placebo in patients...
    Medical condition: Mild to moderate plaque psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-002010-35 Sponsor Protocol Number: TinnEx Start Date*: 2006-12-14
    Sponsor Name:Prof. Herta Flor, Head of the Institute of Clinical and Cognitive Neuroscience
    Full Title: An Extinction Training in Tinnitus
    Medical condition: The effect of pregabalin on the success to reduce the interference by tinnitus by an extinction training is tested in chronic tinnitus sufferers.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005006-31 Sponsor Protocol Number: EML053774_002 Start Date*: 2007-04-03
    Sponsor Name:Merck Sante France
    Full Title: A randomized, stratified on age, parallel group design study to investigate the safety, tolerability and pharmacokinetics after a 60 minutes application of 4% lidocaine cream compared to EMLA® crea...
    Medical condition: Topical anesthesia of healthy skin before venous or subcutaneous puncture, before superficial cutaneous instrumental surgery or laser beam (tattoo or cutaneousangioma)
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-004176-13 Sponsor Protocol Number: SPP635CRD04 Start Date*: 2006-10-11
    Sponsor Name:Speedel Pharma Ltd.
    Full Title: A Phase IIa, Double-Blind, Placebo-Controlled, Randomised, Parallel-Design, Four-week Study to Investigate the Safety and Efficacy of Oral SPP635 450 mg Once Daily in Patients With Mild to Moderate...
    Medical condition: mild to moderate hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-005474-25 Sponsor Protocol Number: DC2021DESIGN1 Start Date*: 2023-08-03
    Sponsor Name:VUmc – Internal medicine / Diabetes Center
    Full Title: DiEtary Sodium Intake effects on ertugliflozin-induced changes in GFR, reNal oxygenation and systemic hemodynamics: the DESIGN study, a randomized, placebo-controlled, cross-over study with ertugli...
    Medical condition: Type 2 Diabetes Mellitus
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-005481-36 Sponsor Protocol Number: L_9795 Start Date*: 2006-06-22
    Sponsor Name:Sanofi-Synthelabo Produtos Farmaceuticos, S.A.
    Full Title: Alfuzosin in Uretheric Stones
    Medical condition: Uretheric Stones
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-003693-17 Sponsor Protocol Number: KetKet_2008 Start Date*: 2008-09-10
    Sponsor Name:Leiden University Medical Center
    Full Title: Treatment of Complex Regional Pain Syndrome type I: A randomised, double-blind, placebo-controlled study with multiple rounds of S(+)-ketamine infusions
    Medical condition: Chronic CRPS ian
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001642-18 Sponsor Protocol Number: WP3 Start Date*: 2019-12-05
    Sponsor Name:Department of Ophthalmology, Rigshospitalet-Glostrup
    Full Title: Effect on the ocular surface when treating glaucoma with eye drops: an investigation of the conjunctival goblet cells
    Medical condition: Open angular glaucoma and ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-003513-41 Sponsor Protocol Number: 15072011 Start Date*: 2011-10-27
    Sponsor Name:Danish Headache Center
    Full Title: A study of the farmacokinetic effect of telmisartan on the serum concentration of verapamil and the prophylactic effect of verapamil on clusterheadache.
    Medical condition: Horton's Headache
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10020397 Horton's headache LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002175-40 Sponsor Protocol Number: no number Start Date*: 2008-12-17
    Sponsor Name:
    Full Title: Effect of Botulinum Toxin A Injections and Specific Intensive Rehabilitation Therapy in Children with Hemiparetic Cerebral Palsy on Upper Limb Functions and Skills
    Medical condition: Study design: a factorial design with four study groups in which btA alone, intensive rehabilitation therapy aimed at improving bimanual skills alone, a combination of these two and continuing the ...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000585-38 Sponsor Protocol Number: SQ411218 Start Date*: 2019-08-20
    Sponsor Name:University Hospitals Coventry and Warwickshire NHS Trust
    Full Title: Chronic Endometritis and Recurrent Miscarriage - The CERM trial
    Medical condition: Chronic Endometritis and Recurrent Miscarriage
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2012-005097-66 Sponsor Protocol Number: NCAG2512 Start Date*: 2014-07-14
    Sponsor Name:HOMVIORA Arzneimittel - Dr. Hagedorn GmbH & Co.
    Full Title: Effect of two homeopathic preparations on blood pressure in comparison to metoprolol (trade name Beloc-Zok® mite 47,5 mg) in 90 patients suffering from mild hypertonia. A prospective, confirmator...
    Medical condition: Patients suffering from mild hypertonia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004507-23 Sponsor Protocol Number: 3112004 Start Date*: 2016-03-15
    Sponsor Name:Orion Corporation
    Full Title: Efficacy and safety of ODM-104 compared to a standard combination (Stalevo); a randomised, double-blind, crossover proof-of-concept study in patients with Parkinson's disease and end-of-dose wearin...
    Medical condition: Parkinson's disease (PD) patients with end-of-dose wearing-off (motor fluctuations)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) DE (Completed) HU (Completed) FI (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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