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Clinical trials for Emetics

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    22 result(s) found for: Emetics. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2016-002924-99 Sponsor Protocol Number: NL.58160.091.16 Start Date*: 2016-10-27
    Sponsor Name:Radboudumc
    Full Title: The effectiveness of deep versus moderate neuromuscular blockade during laparoscopic donor nephrectomy in enhancing postoperative recovery.
    Medical condition: Live kidney donation is currently the most effect strategy to manage the shortage of donor kindeys for transplantation. Optimizing the safety and postoperative recovery after laparoscopic donornep...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-004834-40 Sponsor Protocol Number: THA_glucocorticoids_Ro105 Start Date*: 2020-05-15
    Sponsor Name:University Hospitals Leuven
    Full Title: Do peri-operative high doses of intravenous glucocorticoids improve short-term functional outcome after direct anterior total hip arthroplasty? A randomized, single surgeon, placebo controlled, dou...
    Medical condition: Functional recovary after total hip arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004451-37 Sponsor Protocol Number: VATS-SVP Start Date*: 2012-11-27
    Sponsor Name:Per F. Jensen
    Full Title: Multimodal analgesia in video-assisted thoracic surgery with interostal catheter and glucocorticoid - a randomized, double-blind, placebo-controlled study.
    Medical condition: Pain after thoracoscopic surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-005309-30 Sponsor Protocol Number: 1 Start Date*: 2014-03-13
    Sponsor Name:Fondazione IRCCS Istituto Nazionale dei Tumori
    Full Title: open label, randomized, pilot study on the activity of olanzapine with or without delayed dexamenthasone versus dexamenthasone alone for the prevention of delayed nausea and vomiting in patients wi...
    Medical condition: Patients with gynecologic tumors candidate to chemotherapy with carboplatinum and paclitaxel
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001485-42 Sponsor Protocol Number: NL65290.091.18 Start Date*: 2018-06-14
    Sponsor Name:Radboudumc
    Full Title: RECOVER study: the effect of low- versus normal pressure pneumoperitoneum during laparoscopic colorectal surgery on the early quality of recovery with perioperative care according to the enhanced r...
    Medical condition: Laparoscopic colorectal surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022894-32 Sponsor Protocol Number: RG_10-209 Start Date*: 2011-02-16
    Sponsor Name:University of Birmingham
    Full Title: Dexamethasone Reduces Emesis After Major gastrointestinal Surgery (DREAMS trial) - A prospective, double-blind, multicentre, randomised control trial
    Medical condition: Patients undergoing nausea and vomiting following elective colorectal resections
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022170-14 Sponsor Protocol Number: DN10007 Start Date*: 2010-12-16
    Sponsor Name:Acacia Pharma Ltd
    Full Title: Open-label, ascending-dose, Phase II study to determine the minimum effective dose of APD421 (intravenous amisulpride) in the prevention of cisplatin-induced nausea and vomiting
    Medical condition: Cisplatin-induced nausea and vomiting
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10054133 Prophylaxis of nausea and vomiting PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-002294-38 Sponsor Protocol Number: DANSAC-open Start Date*: 2015-08-31
    Sponsor Name:Odense University Hospital
    Full Title: DANSAC-open: A multicenter, open label study to investigate the efficacy and tolerability of olanzapine in patients with advanced cancer not receiving chemotherapy or irradiation.
    Medical condition: Nausea and/or vomiting
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000017043 10014542 Emesis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-003070-33 Sponsor Protocol Number: DANSAC-RCT Start Date*: 2015-11-30
    Sponsor Name:Odense University Hospital
    Full Title: DANSAC-RCT: Fosaprepitant in patients with advanced cancer not receiving chemotherapy or irradiation; A multicenter, randomized, double-blind, placebo-controlled study.
    Medical condition: Emesis
    Disease: Version SOC Term Classification Code Term Level
    18.1 10017947 - Gastrointestinal disorders 10028817 Nausea and vomiting symptoms HLT
    18.1 10017947 - Gastrointestinal disorders 10014542 Emesis LLT
    18.1 10017947 - Gastrointestinal disorders 10028813 Nausea PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000476-14 Sponsor Protocol Number: TCI_BRIVA Start Date*: 2013-05-07
    Sponsor Name:LANDSTINGET I ÖSTERGÖTLAND
    Full Title: TARGET-CONTROLLED INFUSION (TCI) WITH PROPOFOL AND REMIFENTANIL AS ANALGO-SEDATION IN WOUND CARE IN PATIENTS WITH BURNS
    Medical condition: Burn patients who need analgo-sedation during wound care.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004863 10028175 Multiple burns LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003713-28 Sponsor Protocol Number: 2014-08 Start Date*: 2014-11-06
    Sponsor Name:Univeritetssjukhuset Örebro [...]
    1. Univeritetssjukhuset Örebro
    2. Universitetssjukhuset Örebro
    Full Title: What is the post operative opioid-reducing effect of the beta-receptor-agonist esmolol when administered during laparoscopic gastric by-pass surgery? Comparison between standard anesthesia and anes...
    Medical condition: Effect on post operative opioid consumption after laparoscopic gastric by-pass in obese
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005502-29 Sponsor Protocol Number: 2011-441 Start Date*: 2012-01-12
    Sponsor Name:Mona R Gätke
    Full Title: Optimization of surgical conditions during laparoscopic cholecystectomy with deep or moderate neuromuscular blockade
    Medical condition: Surgical conditions during laparoscopic cholecystectomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10008611 Cholecystectomy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003679-32 Sponsor Protocol Number: 984 Start Date*: 2021-11-25
    Sponsor Name:Sint Maartenskliniek
    Full Title: Erector spinae plane block for reduction of early postoperative pain scores and opioid use in lumbar spinal fusion surgery, a prospective double-blinded randomized placebo controlled trial
    Medical condition: Patients planned to undergo elective lumbar spinal fusion surgery with a dorsal surgical approach
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005775-16 Sponsor Protocol Number: SUBLIME1 Start Date*: 2012-06-19
    Sponsor Name:Research and Development Department
    Full Title: A randomised, double blind, placebo-controlled trial of continuous subpectoral local anaesthetic infusion for pain and shoulder function following mastectomy.
    Medical condition: Post-operative pain following mastectomy surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10024758 Local anaesthesia PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005978-51 Sponsor Protocol Number: TED6421 Start Date*: 2008-08-22
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: Uncontrolled, multicenter, dose finding, safety and pharmacokinetic study of AVE1642, an anti-Insulin-like Growth Factor-1 Receptor (IGF-1R/ CD221) monoclonal antibody, administered as single agent...
    Medical condition: Advanced solid tumors
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005679-18 Sponsor Protocol Number: GMX04 Start Date*: 2011-12-07
    Sponsor Name:Bio Products Laboratory Limited
    Full Title: A Phase IV, Multicenter, Open-Label Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases (PID) in Children and Adolescents
    Medical condition: Primary immunodeficiency diseases
    Disease: Version SOC Term Classification Code Term Level
    14.0 10005329 - Blood and lymphatic system disorders 10005329 Blood and lymphatic system disorders SOC
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: Removed from public view
    EudraCT Number: 2005-004279-39 Sponsor Protocol Number: BUP4004 Start Date*: 2006-01-25
    Sponsor Name:Napp Pharmaceuticals Limited
    Full Title: An open, randomised, multicentre study to compare buprenorphine transdermal delivery system (BTDS) with standard treatment in elderly subjects with OA of the hip and/or knee.
    Medical condition: Severe osteoarthritic pain of the hip(s) and/or knee(s)
    Disease: Version SOC Term Classification Code Term Level
    8.0 10003239 PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-002652-81 Sponsor Protocol Number: DEXLEV01 Start Date*: 2017-10-17
    Sponsor Name:Eske Kvanner Aasvang
    Full Title: High dose steroids in liver resection – effects on complications and endothelial function in the immediate postoperative phase. A randomized, double-blind, controlled trial
    Medical condition: Complications after liver resections - due to liver disease (mainly primary liver cancer and metastases)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000020453 10036278 Postoperative complications NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-003956-32 Sponsor Protocol Number: POSTPAL Start Date*: 2016-03-15
    Sponsor Name:Umeå University
    Full Title: Effects of postoperative palonosetron in ambulatory patients identified with high risk for postdischarge nausea and vomiting (PDNV) – a randomized controlled trial with comparison to placebo.
    Medical condition: Nausea and vomiting in the home (after discharge) after day-case surgery under general anesthesia-
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004856 10028817 Nausea and vomiting symptoms HLT
    18.1 100000004863 10036285 Postoperative nausea LLT
    18.1 100000004865 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    18.1 100000004865 10054182 Perioperative nausea and vomiting prophylaxis LLT
    18.1 100000004863 10028818 Nausea postoperative LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2014-005623-27 Sponsor Protocol Number: RM-131-009 Start Date*: 2015-04-08
    Sponsor Name:Rhythm Pharmaceuticals, Inc.
    Full Title: A Phase 2b, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of RM-131 Administered to Patients with Vomiting Symptoms and Moderate to Severe Diabetic Gastropa...
    Medical condition: Vomiting symptoms in patient with moderate to severe diabetic gastroparesis
    Disease: Version SOC Term Classification Code Term Level
    17.1 10017947 - Gastrointestinal disorders 10051153 Diabetic gastroparesis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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