Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Endarterectomy

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    44 result(s) found for: Endarterectomy. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2009-016902-17 Sponsor Protocol Number: CLINMEDINT001 Start Date*: 2012-05-18
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA OSPEDALI RIUNITI UMBERTO I - G.M.LANCISI - G.SALESI
    Full Title: Direct renin inhibitor (aliskiren)and carotid plaques instability markers in hypertensive patients requiring carotid endoarterectomy
    Medical condition: Essential hypertension.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059238 LLT
    9.1 10007692 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2008-005246-23 Sponsor Protocol Number: ARC1779-008 Start Date*: 2008-12-17
    Sponsor Name:Archemix Corp.
    Full Title: A Study of the Effect of ARC1779 Injection on Cerebral Microembolism in Patients Undergoing Carotid Endarterectomy
    Medical condition: Patients undergoing carotid endarterectomy,
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007692 Carotid endarterectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-003470-88 Sponsor Protocol Number: 11-195 Start Date*: 2012-07-30
    Sponsor Name:University Medical Center Utrecht, The Netherlands
    Full Title: Phenylephrine versus EPhedrine on cerebral Perfusion during carotid EndarteRectomy: PEPPER study
    Medical condition: Hypotension during carotid endarterectomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10062300 Procedural hypotension PT
    14.1 10042613 - Surgical and medical procedures 10007692 Carotid endarterectomy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004209-27 Sponsor Protocol Number: 05/Q1606/127 Start Date*: 2005-11-11
    Sponsor Name:Oxford Radcliffe Hospitals NHS Trust
    Full Title: Effect of altering inspired oxygen concentrations on cerebral oxygenation during awake carotid surgery
    Medical condition: Carotid endarterectomy is an operation performed on patients with a symptomatic stenosis of the internal carotid artery. Such patients have usually presented with stroke or transient ischaemic atta...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2014-001338-27 Sponsor Protocol Number: 2014-001338-27 Start Date*: 2014-06-19
    Sponsor Name:Helsinki University Central hospital
    Full Title: Influence of propofol and desfluran on the cerebral circulation and recovery after anesthesia
    Medical condition: Carotid endarterectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-018166-36 Sponsor Protocol Number: XENON-2009 Start Date*: 2010-03-18
    Sponsor Name:CHU de Poitiers
    Full Title: Evaluation de l’entretien de l’anesthésie générale sous Xénon comparé au Desflurane au cours de l’endartérectomie carotidienne, étude prospective, randomisée et comparative.
    Medical condition: Carotid artery stenosis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10007687 Carotid artery stenosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002769-37 Sponsor Protocol Number: cervikalblock Start Date*: 2012-10-23
    Sponsor Name:UK für Anästhesiologie und allgemeine Intensivmedizin, LKH Salzburg
    Full Title: Influence of the concentration of the local anesthetic ropivacaine in the quality of a ultrasound guided block of the regio collis lateralis for carotid endarterectomy: a prospective, randomized an...
    Medical condition: Regional anesthesia for carotid endarterectomy surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000543-27 Sponsor Protocol Number: 19852012 Start Date*: 2012-04-23
    Sponsor Name:AMC
    Full Title: A Proof of Concept Study to Determine the Local Delivery and Efficacy of Intravenously Injected PEG-Liposomal Prednisolone Sodium Phosphate (Nanocort®) in Atherosclerotic Tissue in Subjects with Pe...
    Medical condition: Vessel wall inflammation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002452-16 Sponsor Protocol Number: PTO95105013 Start Date*: 2020-02-04
    Sponsor Name:UMC Utrecht
    Full Title: Inhibition of Mast cell Activation in AtheroScleroTic lesions using an Anti-IgE antibody approach (MAST-trial)
    Medical condition: Atherosclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-008006-46 Sponsor Protocol Number: 0000-111 Start Date*: 2009-05-20
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Randomized Clinical Trial to Evaluate the Effects of High Dose Statin and Niacin Therapy on Excised Plaque Biomarkers in Patients Undergoing Carotid Endarterectomy (CEA)
    Medical condition: carotid atherosclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003601 Atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-000456-17 Sponsor Protocol Number: 43466 Start Date*: 2019-10-16
    Sponsor Name:University Hospital Maastricht
    Full Title: Plaque at risk (ParisK): Molecular imaging of plaque vulnerability using 18F-choline PET-CT and MRI in carotid artery atherosclerosis patients
    Medical condition: Patients with carotid artery stenosis due to atherosclerosis, who are scheduled for carotid endarterectomy or are treated conservatively.
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10066537 Atherosclerosis prophylaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000176-17 Sponsor Protocol Number: CL2 – 18886 – 026 Start Date*: 2007-09-07
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Effects of terutroban versus aspirin on composition of atherosclerotic plaque in patients undergoing a carotid endarterectomy.A multicentre, randomised, double blind, two parallel group study compa...
    Medical condition: Ischaemic stroke or transient ischaemic attack
    Disease: Version SOC Term Classification Code Term Level
    7.0 10008190 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-000072-25 Sponsor Protocol Number: IG402 Start Date*: 2008-08-04
    Sponsor Name:Instituto Grifols S.A.
    Full Title: Estudio prospectivo, simple ciego, de Fase II/III para evaluar la Seguridad y Eficacia del Adhesivo de Fibrina Grifols (FS Grifols) como un Adyuvante a la Hemostasia durante Cirugía Vascular Perifé...
    Medical condition: Adyuvante a la hemostasia en cirugía vascular periférica. Adjunct to hemostasis during peripheral vascular surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-002911-16 Sponsor Protocol Number: na Start Date*: 2016-12-28
    Sponsor Name:Maastricht University Medical Center
    Full Title: PET/MRI and plaque vulnerability A feasibility study of 18F-Flutemetamol in atherosclerosis
    Medical condition: Atherosclerosis in the carotids and coronary arteries.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-001300-30 Sponsor Protocol Number: 2017_CERVPLEX_1.1 Start Date*: 2017-10-03
    Sponsor Name:UK für Anästhesieologie, Gemeinn. Sbg. Landeskliniken BetriebsgesmbH
    Full Title: Comparison of deep, intermediate and superficial cervical plexus block for carotid endarterectomies concerning paresis of the phrenic nerve, lung function and tissue distribution: a prospective, ra...
    Medical condition: deep, intermediate or superficial cervical plexus block for carotid endarterectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001121-40 Sponsor Protocol Number: PEA_Bridging_Study Start Date*: 2018-09-17
    Sponsor Name:International CTEPH Association (ICA)
    Full Title: A Phase 2, Randomised, Double-Blind, Placebo-Controlled, Multicentre, Prospective Study to Assess Efficacy of Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy With High P...
    Medical condition: Chronic Thromboembolic Pulmonary Disease (CTEPH)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10068740 CTEPH LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Prematurely Ended) FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-006611-29 Sponsor Protocol Number: 80009 Start Date*: 2022-06-28
    Sponsor Name:University Medical Centre Utrecht Department of Vascular Surgery
    Full Title: A randomized placebo-controlled double-blind trial studying the effect of antiplatelet monotherapy (clopidogrel) versus dual antiplatelet therapy (clopidogrel + aspirin) on the occurrence of athero...
    Medical condition: (Chronic) Peripheral (occlusive) arterial disease (PAD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000072-16 Sponsor Protocol Number: BAY63-2521/11348 Start Date*: Information not available in EudraCT
    Sponsor Name:Bayer HealthCare AG
    Full Title: Randomized, double-blind, placebo-controlled, multi-centre, multi-national study to evaluate the efficacy and safety of oral BAY 63-2521 (1 mg, 1.5 mg, 2 mg, or 2.5 mg tid) in patients with Chronic...
    Medical condition: Chronic Thromboembolic Pulmonary Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10037406 Pulmonary hypertension secondary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IE (Prematurely Ended) GB (Completed) AT (Completed) ES (Completed) NL (Completed) FR (Completed) IT (Completed) BE (Completed) CZ (Completed) SK (Completed) PT (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-001635-21 Sponsor Protocol Number: VIA-2291-02 Start Date*: 2006-12-21
    Sponsor Name:VIA PHARMACEUTICALS, INC.
    Full Title: A Phase 2 Randomised, Double-blind, Placebo-controlled Study of the Effects of VIA-2291, a 5-lipoxygenase Inhibitor, on Atherosclerotic Plaque and Biomarkers of Vascular Inflammation in Patients wi...
    Medical condition: Carotid Stenosis.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10047065 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005338-35 Sponsor Protocol Number: PM1111138 Start Date*: 2009-04-01
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A double-blind, placebo-controlled, parallel group study to evaluate the effects of two regimens of GW856553, over a period of 3 months, on in-vivo macrophage activity, as assessed by FDG-PET/CT im...
    Medical condition: GW-856553 is under development as a potential anti-atherosclerosis agent for reduction of major cardiovascular events in high risk patient populations.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003601 Atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Tue May 20 14:58:04 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA