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Clinical trials for Enteral administration

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    54 result(s) found for: Enteral administration. Displaying page 1 of 3.
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    EudraCT Number: 2004-001299-38 Sponsor Protocol Number: EMULIP Start Date*: 2004-11-26
    Sponsor Name:Metabolism and Nutrition Group of the SEMICYUC
    Full Title: Study prospective, multicenter, randomized, comparative, double blind, to evaluate two different lipidic emulsions in the total parenteral nutrition of the critic patient and their influence in the...
    Medical condition: Patients in whom the necessity is foreseen to receive metabolic total parenteral nutrition like nutritional support, during a minimum period of 7 days, because they can not to be fed by route enter...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003411-19 Sponsor Protocol Number: CPU-003 Start Date*: 2017-11-09
    Sponsor Name:Fakultní nemocnice u sv. Anny v Brně
    Full Title: Compatibility of clopidogrel prepared for administration through nasogastric tube with enteral nutrition (CPU-003)
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003626-91 Sponsor Protocol Number: CAFSP01 Start Date*: 2019-04-09
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
    Full Title: CAFFEINE TREATMENT IN DELIVERY ROOM FOR VERY PRETERM INFANTS : A FEASIBILITY STUDY
    Medical condition: 25+0-29+6 gestational age preterm infants at risk of respiratory distress syndrome with no need of mechanical ventilation in delivery room.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004868 10021734 Infant premature LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004260-22 Sponsor Protocol Number: ELFIN01 Start Date*: 2013-08-28
    Sponsor Name:University of Oxford
    Full Title: A multi-centre randomised placebo-controlled trial of prophylactic enteral lactoferrin supplementation to prevent late-onset invasive infection in very preterm infants.
    Medical condition: Late onset invasive infection in very preterm infants
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-006179-20 Sponsor Protocol Number: INSULINE Start Date*: 2013-01-04
    Sponsor Name:Endocrinology and Nutrition Unit. Hospital Universitari Bellvitge.
    Full Title: Comparative randomized clinical trial between insulin analogues and human insulin in hospitalized patients treated with enteral nutrition and who present hyperglycemia. INSULINE study.
    Medical condition: Pacients receiving enteral nutrition and who present hyperglycemia.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004687-37 Sponsor Protocol Number: 14SM2335 Start Date*: 2016-06-17
    Sponsor Name:Imperial College Healthcare NHS Trust
    Full Title: Use of Methylnaltrexone for the Treatment of Opioid Induced Constipation & Gastro-Intestinal Stasis in Intensive Care Patients
    Medical condition: Opioid Induced Constipation
    Disease: Version SOC Term Classification Code Term Level
    17.1 10017947 - Gastrointestinal disorders 10010774 Constipation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004541-34 Sponsor Protocol Number: 21092005 Start Date*: 2006-02-14
    Sponsor Name:South Manchester University Healthcare Trust
    Full Title: The Effect of Enteral Administration of Synbiotics Upon Infection Rates in Major Burns
    Medical condition: Major burn injuries: Thermal related trauma with burn injury involving significant proportions of the total body surface area, as defined by age: Adults (>=17 years old): >= 15% body surface area ...
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-002744-89 Sponsor Protocol Number: 20130620 Start Date*: 2014-01-27
    Sponsor Name:Erasmus MC
    Full Title: Bioavailability of oral ciprofloxacin tablets and suspension in pediatric cancer patients
    Medical condition: Microbial prophylaxis during cancer treatment
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-003557-15 Sponsor Protocol Number: HMB-ICU Start Date*: 2018-08-31
    Sponsor Name:Guy's and St Thomas NHS Foundation Trust
    Full Title: A Study to Investigate the Effect of β-Hydroxy-β-Methylbutyrate (HMB) on Skeletal Muscle Wasting in Early Critical Illness.
    Medical condition: Critical illness
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10077264 Critical illness PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-000882-19 Sponsor Protocol Number: P160949J Start Date*: 2020-07-15
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Efficacy of add-on PEramPanel in focal motor Status epilepticus
    Medical condition: Patients with a focal motor status epilepticus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-004473-16 Sponsor Protocol Number: SL001-2.0 Start Date*: 2016-07-19
    Sponsor Name:Masarykův onkologický ústav
    Full Title: Prospective study investigating efficacy of lanreotide on decrease of chemotherapy induced diarrhoea (CID) in patiens with colorectal carcinoma.
    Medical condition: Chemotherapy induced diarrhoea that is resistant to common treatment including loperamide in patients with colorectal carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-003445-17 Sponsor Protocol Number: BBG001 Start Date*: 2009-05-12
    Sponsor Name:Queen Mary, University of London
    Full Title: The probiotic Bifidobacterium breve strain BBG-01 admistered early to preterm infants to prevent infection, necrotising enterocolitis and death.
    Medical condition: Necrotising enterocolitis in the preterm baby Late-onset (>72h of age) blood stream infection in the preterm baby Death of preterm babies before discharge from hospital
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-017137-22 Sponsor Protocol Number: 190178 Start Date*: 2013-04-16
    Sponsor Name:Klinische Abteilung für Thorax -u. Hyperbare Chirurgie, Medizinische Universität Graz
    Full Title: Clinical course after substitution of Vitamin-D deficiency in patients with lung cancer or oesophageal carcinoma. Double blind randomised prospective, placebo-controlled study.
    Medical condition: Patients admitted for treatment on a general thoracic surgery division with the following conditions: Lung cancer Esophageal cancer Cancer of the gastroesophageal junction (GEJ)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-002093-23 Sponsor Protocol Number: 1.01 Start Date*: 2011-09-21
    Sponsor Name:University of Tartu
    Full Title: Bioavailability of oral N-acetylcysteine in different intensive care unit patient groups
    Medical condition: Severe neurotrauma, severe pulmonary infections and severe gastrointestinal disease (eg peritonitis, pancreatitis, ileus, major abdominal surgery etc). Need for liquefaction of viscous sputum
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: EE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001723-10 Sponsor Protocol Number: 767905/012 Start Date*: 2005-08-26
    Sponsor Name:GlaxoSmithKline R & D Limited
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Efficacy and Safety of Alvimopan 0.5mg Once Daily and 0.5mg Twice Daily for 12 Weeks for the Treatment of O...
    Medical condition: Opioid-induced bowel dysfunction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) FI (Completed) GB (Completed) DE (Completed) DK (Completed) EE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-002053-19 Sponsor Protocol Number: CLMI070X2201 Start Date*: 2014-12-16
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An open-label multi-part first-in-human study of oral LMI070 in infants with Type 1 spinal muscular atrophy
    Medical condition: Spinal Muscular Atrophy
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004850 10051203 Spinal muscular atrophy congenital LLT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed) IT (Completed) DE (Completed) BE (Completed) NL (Ongoing) CZ (Completed) PL (Completed) HU (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2005-001725-28 Sponsor Protocol Number: 767905/014 Start Date*: 2005-08-26
    Sponsor Name:GlaxoSmithKline R & D Limited
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Long-Term Safety of Alvimopan 0.5mg Twice Daily for 12 Months for the Treatment of Opioid-Induced Bowel Dys...
    Medical condition: Opioid-induced bowel dysfunction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) FI (Completed) SE (Completed) GB (Completed) HU (Completed) AT (Completed) DK (Completed) PT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-001724-37 Sponsor Protocol Number: 767905/013 Start Date*: 2005-09-08
    Sponsor Name:GlaxoSmithKline R & D Limited
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Efficacy and Safety of Alvimopan 0.5mg Once Daily and 0.5mg Twice Daily for 12 Weeks for the Treatment of O...
    Medical condition: Opioid-induced bowel dysfunction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) HU (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-002871-32 Sponsor Protocol Number: Rifabupre Start Date*: 2012-08-28
    Sponsor Name:Turku University hospital
    Full Title: Effects of rifampicin on the pharmacokinetics and pharmacodynamics of sublingual and intravenous buprenorphine: A four-phase cross-over study in healthy subjects.
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002109-70 Sponsor Protocol Number: E6011-ET2 Start Date*: 2019-04-15
    Sponsor Name:EA Pharma Co., Ltd.
    Full Title: Early phase 2 clinical trial of E6011 in patients with active Crohn’s disease
    Medical condition: Active Crohn’s disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10011401 Crohn's disease PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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