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Clinical trials for Environmental factors

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    32 result(s) found for: Environmental factors. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2008-005395-27 Sponsor Protocol Number: 4705 Start Date*: 2009-01-27
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: Inter-individual variability in response to warfarin in children: Analysis of environmental and pharmacogenetic factors
    Medical condition: The study population will consist of children (0-18 years of age) who are anticoagulated with warfarin.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051445 Foetal warfarin syndrome LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001910-40 Sponsor Protocol Number: 0305070107 Start Date*: 2020-06-09
    Sponsor Name:Radboud University
    Full Title: Combining emotion recognition training with oxytocin administration: A psychobiological approach
    Medical condition: We examine whether oxytocin administration can improve the effectiveness of emotion recognition training compared to placebo in residential youth with antisocial behavior
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003588-85 Sponsor Protocol Number: PSYCHIC Start Date*: 2022-01-11
    Sponsor Name:UCLouvain
    Full Title: Individualized care with antipsychotics in patients suffering from schizophrenia spectrum disorders- How to conciliate plasma concentrations, clinical response and genetic factors ?
    Medical condition: Schizophrenia, schizoaffective disorders, psychosis not otherwise specified, and dellusional disorders
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001587-70 Sponsor Protocol Number: 07/03 Inopec ITEM Start Date*: 2007-06-07
    Sponsor Name:Fraunhofer Gesellschaft
    Full Title: A randomized, double-blind, placebo-controlled crossover study to assess the efficacy's reproducibility of a combination of Pseudoephedrine and Cetirizine on symptom scores and rhinomanometry in pa...
    Medical condition: subjects with seasonal allergic rhinitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002708-13 Sponsor Protocol Number: SP002 Start Date*: 2004-12-27
    Sponsor Name:Synergia Pharma, Inc.
    Full Title: A RANDOMIZED, BLINDED, CROSSOVER TRIAL OF A SINGLE DOSE OF ORAL L-DOPS 300 MG IN AN ENVIRONMENTAL EXPOSURE UNIT IN SUBJECTS WITH SEASONAL ALLERGIC RHINITIS
    Medical condition: seasonal allergic rhinitis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10039776 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002720-16 Sponsor Protocol Number: CPPM2013 Start Date*: 2014-10-08
    Sponsor Name:Stockholms Läns Sjukvårdsområde (SLSO)
    Full Title: EMPHAS I Evaluation of Methylphenidate (MPH) in adults with ADHD and SUD - clinical pharmacology study A Cross-sectional, Open-label, Non-randomized Single-Center Study on Adults with ADHD and ...
    Medical condition: ADHD
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020985-94 Sponsor Protocol Number: TH1010 Start Date*: 2010-09-10
    Sponsor Name:Reckitt Benckiser Healthcare (UK) Ltd
    Full Title: A randomised, double blind, placebo-controlled, parallel group, single dose study of the efficacy of a flavoured variant of Strepsils Throat Lozenge in the relief of dry and irritated sore throat d...
    Medical condition: Sore throat
    Disease: Version SOC Term Classification Code Term Level
    12.1 10041367 Sore throat LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005269-20 Sponsor Protocol Number: 6078-PG-PSC-158 Start Date*: 2007-01-15
    Sponsor Name:LETI Pharma GmbH
    Full Title: Randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy of Depigoid® Grass Mix as a rush immunotherapy in patients with allergic rhinitis using an environmental ...
    Medical condition: Allergic rhinitis and/or rhinoconjunctivitis with or without mild intermittent asthma caused by clinical relevant sensitization against grass pollen.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039083 Rhinitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-003340-37 Sponsor Protocol Number: PJ21069 Start Date*: 2018-10-30
    Sponsor Name:Technological University Dublin
    Full Title: Efficacy and Mechanisms of Low Dose Atropine in the Control of Myopia in Children Trial name: Myopia Outcome Study of Atropine in Children (MOSAIC)
    Medical condition: Myopia- a refractive error due to a discrepancy between the anatomical axial length and the focal length of the eye. resulting in distant objects appearing blurred
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10028651 Myopia PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011459-39 Sponsor Protocol Number: HHI112864 Start Date*: 2009-05-28
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A randomised, double-blind, placebo-controlled 4-period crossover study to assess the efficacy and safety of repeat dose intranasal GSK1004723 (1000μg), oral GSK835726 (10mg) and cetirizine (10mg) ...
    Medical condition: Seasonal Allergic Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039776 Seasonal allergic rhinitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-003000-35 Sponsor Protocol Number: Final Version 1.0 Hyposensitisation Start Date*: 2007-07-09
    Sponsor Name:Department of Occupational and Environmental Dermatology, Malmö University Hospital
    Full Title: A randomized controlled single blind multicenter study to investigate the induction of aluminium contact allergy in children/adults receiving hyposensitisation therapy due to allergic disease. Chi...
    Medical condition: The development of contact allergy to aluminium during hyposensitization therapy.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000309-10 Sponsor Protocol Number: CHUBX2017/45 Start Date*: 2021-10-04
    Sponsor Name:CHU de Bordeaux
    Full Title: Phase II/III double-blind randomized placebo-controlled trial assessing the preventive effect of Clopidogrel on the systemic sclerosis development risk in subjects with specific dysimmunity and Ray...
    Medical condition: Raynaud phenomenon
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10037914 Raynaud's syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-004255-10 Sponsor Protocol Number: 6078-PG-PSC-164 Start Date*: 2007-11-12
    Sponsor Name:LETI Pharma GmbH
    Full Title: Randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of Depigoid® Grass Mix in patients with al-lergic rhinitis and/or rhinoconjunctivitis with or ...
    Medical condition: Allergic rhinitis and/or rhinoconjunctivitis with or without mild intermitent asthma caused by clinical relevant sensitization against grass pollen.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001723 Allergic rhinitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-002277-22 Sponsor Protocol Number: AMYPAD-02 Start Date*: 2018-09-12
    Sponsor Name:Stichting VUmc
    Full Title: AMYPAD Prognostic and Natural History Study (PNHS), an open label, prospective, multicentre, cohort study in individuals without dementia to evaluate the additional value of quantitative amyloid im...
    Medical condition: Alzheimer's Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) ES (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003471-39 Sponsor Protocol Number: Miltefosin bei AD Start Date*: 2007-08-24
    Sponsor Name:Prof. Dr. med. Margitta Worm
    Full Title: Explorative analysis of topical miltefosine application in adult patients with atopic dermatitis.
    Medical condition: Atopic Dermatitis (AD) is a chronic, inflammatory skin disease combined with intense itching. Beside the existing genetic background, various environmental factors impact the pathophysiology. Topic...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004092-22 Sponsor Protocol Number: HH3110163 Start Date*: 2008-09-03
    Sponsor Name:GlaxSmithKline Research & Development Limited
    Full Title: A randomised, double-blind, placebo-controlled, 4-period incomplete block crossover study of single oral dose GSK835726 (100mg, 50mg, 10mg), Cetirizine (10mg) and placebo to evaluate the efficacy a...
    Medical condition: Seasonal Allergic Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039776 Seasonal allergic rhinitis LLT
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-000115-11 Sponsor Protocol Number: VR1111924 Start Date*: 2011-04-19
    Sponsor Name:GlaxoSmithKline Research and Development Ltd
    Full Title: A randomized, double-blind, placebo controlled, incomplete block, 3 way cross over study in subjects with allergic rhinitis to assess the effect of intranasal repeat doses of SB-705498 when adminis...
    Medical condition: Allergic rhinitis.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10001723 Allergic rhinitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-002738-22 Sponsor Protocol Number: 62388 Start Date*: 2018-03-02
    Sponsor Name:Princess Máxima Center of Pediatric Oncology
    Full Title: Double blind placebo controlled randomized intervention study to validate the beneficial effect of hydrocortisone on dexamethasone-induced neurobehavioral side effects in pediatric acute lymphoblas...
    Medical condition: Acute lymphoblastic leukemia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10024338 Leukemia lymphoblastic acute LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-002940-94 Sponsor Protocol Number: 200286 Start Date*: 2013-10-23
    Sponsor Name:GlaxoSmithKline
    Full Title: A randomised, double-blind, placebo-controlled, 3 way, incomplete block cross over study in subjects with allergic rhinitis to assess the effect of once daily single and repeat doses of intranasal ...
    Medical condition: Allergic rhinitis (AR) in its seasonal and perennial form is a common allergic condition. It is clinically defined as a symptomatic disorder induced by immunoglobulin E (IgE)- mediated inflammatio...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004509-29 Sponsor Protocol Number: 2012-776 Start Date*: 2015-11-03
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Antidepressant treatments during pregnancy and lactation: prediction of drug exposure through breastfeeding and evaluation of drug effect on the neonatal adaptation and the development of the youn...
    Medical condition: depression
    Disease: Version SOC Term Classification Code Term Level
    18.0 10037175 - Psychiatric disorders 10012378 Depression PT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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