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Clinical trials for Epilepsy

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    385 result(s) found for: Epilepsy. Displaying page 1 of 20.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2016-002313-22 Sponsor Protocol Number: ADV6770-A11CS Start Date*: Information not available in EudraCT
    Sponsor Name:ADVICENNE PHARMA SA
    Full Title: A randomised, active controlled, open-label, 2-way cross-over, multicentre study to investigate the palatability, acceptability, pharmacokinetics, safety and tolerability, and treatment compliance ...
    Medical condition: Children with chilhood absence epilepsy.
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10000332 Absence seizures HLT
    19.0 10029205 - Nervous system disorders 10034759 Petit mal epilepsy PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001514-29 Sponsor Protocol Number: LAM115377 Start Date*: 2017-08-11
    Sponsor Name:GlaxoSmithKline KK
    Full Title: A multi-center, uncontrolled, open-label, evaluation of Lamotrigine monotherapy on newly diagnosed typical absence seizures in children and adolescents
    Medical condition: Typical absence seizure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000014665 10000331 Absence seizure LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-004146-40 Sponsor Protocol Number: LEV Start Date*: 2005-03-10
    Sponsor Name:ISTITUTI FISIOTERAPICI OSPITALIERI
    Full Title: pILOT STUDY TO EVALUATE QUALITY OF LIFE, SEIZURES CONTROL AND SIDE EFFECTS IN PATIENTS WITH BRAIN TUMORS AND EPILEPSY TREATED WITH LEVETIRACETAM IN MONOTHERAPY
    Medical condition: TREATMENT OF EPILEPSY IN PATIENTS WITH BRAIN TUMORS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015037 Epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001515-36 Sponsor Protocol Number: 200776 Start Date*: 2017-08-11
    Sponsor Name:GlaxoSmithKline K.K.
    Full Title: Valproate dose reduction and its clinical evaluation by introducing lamotrigine in Japanese women with epilepsy – single arm, multicenter, and open-label study
    Medical condition: Partial seizures (including secondary generalized seizures) or tonic-clonic seizures with or without myoclonus but without other generalized seizure type(s)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000038485 10043999 Tonic-clonic epilepsy LLT
    20.0 100000014703 10065336 Partial epilepsy LLT
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-003520-18 Sponsor Protocol Number: LEV05-1 Start Date*: 2005-07-25
    Sponsor Name:ISTITUTO C. MONDINO
    Full Title: Multicenter, double-blind placebo controlled study of levetiracetam in the treatment of childhood and juvenile absence epilepsy.
    Medical condition: therapy of absence epilepsy
    Disease: Version SOC Term Classification Code Term Level
    6.1 10015037 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004878-15 Sponsor Protocol Number: LAM115376 Start Date*: 2016-12-21
    Sponsor Name:GlaxoSmithKline K.K. (GSK)
    Full Title: A multi-center, uncontrolled, open-label, evaluation of lamotrigine monotherapy in adult subjects with newly diagnosed epilepsy or recurrent epilepsy (currently untreated).
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-004511-27 Sponsor Protocol Number: S64647 Start Date*: 2021-08-05
    Sponsor Name:University Hospital Leuven
    Full Title: Add-on clioquinol in drug-resistant childhood epilepsy: an exploratory study
    Medical condition: Drug resistant epilepsy in children
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-003522-26 Sponsor Protocol Number: LEVFU05-1 Start Date*: 2005-07-25
    Sponsor Name:ISTITUTO C. MONDINO
    Full Title: Open label, multicenter study of levetiracetam in the treatment of childhood and juvenile absence epilepsy
    Medical condition: Efficacy and tolerability within one year of levetiracetam
    Disease: Version SOC Term Classification Code Term Level
    6.1 10015037 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005088-34 Sponsor Protocol Number: 1372-14 Start Date*: 2015-06-17
    Sponsor Name:Cardiff University
    Full Title: A randomised controlled, double blind trial investigating the efficacy of fluoxetine treatment in improving memory and learning impairments in patients with mesial temporal lobe epilepsy: Fluoxetin...
    Medical condition: Mesial Temporal Lobe Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029205 - Nervous system disorders 10043209 Temporal lobe epilepsy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018284-42 Sponsor Protocol Number: LEVVPA Start Date*: 2012-12-19
    Sponsor Name:University Medical Centre Groningen
    Full Title: Double-blind randomized trial comparing efficacy, safety and tolerance between Levetiracetam monotherapy and Valproic acid monotherapy in children with newly diagnosed epilepsy
    Medical condition: epilepsy
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-004376-39 Sponsor Protocol Number: N01340 Start Date*: 2015-02-24
    Sponsor Name:UCB Biosciences, Inc.
    Full Title: An Open-Label, Multicenter, Parallel-Group, Two-Arm Study Comparing the Pharmacokinetics of Keppra XR in Children (Aged 12 - 16 Years Old) With Epilepsy and in Adults (Aged 18 - 55 Years Old) With ...
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-004333-57 Sponsor Protocol Number: N01221 Start Date*: 2015-02-10
    Sponsor Name:UCB Japan Co., Ltd.
    Full Title: A Double-blind, Randomized, Placebo-controlled 5 Parallel Groups, Confirmatory Trial on the Efficacy and Safety of Levetiracetam used as add-on Therapy at doses of 0.5 to 3 g/day in Patients From 1...
    Medical condition: Epilepsies Partial
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-006346-34 Sponsor Protocol Number: N01254 Start Date*: 2007-06-13
    Sponsor Name:UCB Pharma
    Full Title: An international, randomized, double-blind, parallel-group, placebo-controlled, flexible dose study: evaluation of the safety and efficacy of brivaracetam in subjects (>=16 to 70 years old) sufferi...
    Medical condition: Localization-related or generalized epilepsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015037 Epilepsy LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) CZ (Completed) SE (Completed) DE (Completed) AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-001223-23 Sponsor Protocol Number: CAPSS-311 Start Date*: 2015-04-24
    Sponsor Name:Johnson & Johnson Pharmaceutical Research and Development, L.L.C.
    Full Title: TOPAMAX (Topiramate) Initiated as Monotherapy in Epilepsy (TIME): A Multicenter, Outpatient, Open-Label, Study to Evaluate the Dosing, Effectiveness and Safety of TOPAMAX as Monotherapy in the Trea...
    Medical condition: New onset epilepsy
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-005722-23 Sponsor Protocol Number: N01274 Start Date*: 2007-05-15
    Sponsor Name:UCB Pharma S.A.
    Full Title: Open-label, single-arm, multi-center, pharmacokinetic, safety and tolerability study of levetiracetam intravenous infusion in children (4 - 16 years old) with epilepsy.
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015037 Epilepsy LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2016-004958-14 Sponsor Protocol Number: E2090-S082-409 Start Date*: 2017-04-24
    Sponsor Name:Eisai Korea Inc.
    Full Title: A Korean Open-label, Multi-center, Community-based Trial Assessing the Efficacy and Safety of Zonisamide as Adjunctive Therapy in Patients With Uncontrolled Partial Epilepsy
    Medical condition: Epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2011-004156-19 Sponsor Protocol Number: VX11-765-402 Start Date*: 2012-06-21
    Sponsor Name:Vertex Pharmaceuticals Incorporated
    Full Title: A Phase 2b, Randomized, Double Blind, Placebo Controlled, Parallel Group, Dose Ranging Study to Evaluate the Efficacy and Safety of VX-765 in Subjects With Treatment Resistant Partial Epilepsy With...
    Medical condition: Partial epilepsy
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10065336 Partial epilepsy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) AT (Prematurely Ended) HU (Completed) GB (Prematurely Ended) FI (Completed)
    Trial results: View results
    EudraCT Number: 2014-004377-16 Sponsor Protocol Number: N01375 Start Date*: 2015-07-24
    Sponsor Name:UCB Japan Co. Ltd.
    Full Title: An Open-label, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of Levetiracetam Used as Monotherapy in Newly or Recently Diagnosed Epilepsy Patients Aged Older Than or Equal to 16...
    Medical condition: Focal Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-004379-22 Sponsor Protocol Number: SP0961 Start Date*: 2015-03-10
    Sponsor Name:UCB BIOSCIENCES, Inc.
    Full Title: An Open-Label Pilot Study to Assess the Safety of Oral Lacosamide as Adjunctive Therapy for Uncontrolled Primary Generalized Tonic-Clonic Seizures in Subjects With Idiopathic Generalized Epilepsy
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-004898-16 Sponsor Protocol Number: V_1 Start Date*: 2015-05-27
    Sponsor Name:Medizinische Universität Wien
    Full Title: A study to investigate (R)-11C-verapamil PET as a predictive biomarker for epilepsy surgery outcome
    Medical condition: temporal lobe epilepsy
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10043209 Temporal lobe epilepsy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
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