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Clinical trials for External fertilization

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    14 result(s) found for: External fertilization. Displaying page 1 of 1.
    EudraCT Number: 2005-000993-29 Sponsor Protocol Number: 04I/HMG10 Start Date*: 2005-07-19
    Sponsor Name:IBSA
    Full Title: A prospective, randomized, investigator-blind, controlled, clinical study of phase III on the clinical efficacy and tolerability of hMG-IBSA IBSA Institut Biochimique sa versus Menopur Ferring ...
    Medical condition: COH Controlled Ovarian Hyperstimulation in ART Assisted Reproductive Technology /IVF
    Disease: Version SOC Term Classification Code Term Level
    6.1 10056204 PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-004233-27 Sponsor Protocol Number: RF-2013-02358757 Start Date*: 2016-06-23
    Sponsor Name:FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO
    Full Title: Vitamin D Supplementation on Assisted Reproduction Technology (ART) outcomes: a randomized clinical controlled trial and an investigation of the involved biological mechanisms
    Medical condition: in vitro fertilization
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10056204 In vitro fertilisation PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-002385-31 Sponsor Protocol Number: 2015/582 Start Date*: 2017-08-28
    Sponsor Name:Professor Peter Humaidan, The Fertility Clinic Skive
    Full Title: A double-blind, placebo-controlled multicenter trial on the effect of clindamycin and a live biotherapeutic on the reproductive outcomes of IVF patients with abnormal vaginal microbiota
    Medical condition: Infertility
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10021572 In vitro fertilization LLT
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-006595-11 Sponsor Protocol Number: 07EU/Prg06 Start Date*: 2008-09-25
    Sponsor Name:IBSA Institut Biochimique SA
    Full Title: Efficacy and Tolerability of Subcutaneous Progesterone (IBSA) versus Vaginal Progesterone Gel (Crinone) for Luteal Phase Support in Patients Undergoing In-Vitro Fertilization (IVF).
    Medical condition: Patient undergoing in-Vitro Fertilization (IVF)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021572 In vitro fertilization LLT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed) HU (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-002993-29 Sponsor Protocol Number: M13-625 Start Date*: 2015-07-15
    Sponsor Name:Abbott Laboratories GmbH
    Full Title: A Randomized, Open-label, Two-arm, Multicenter Study Comparing the Efficacy, Safety and Tolerability of Oral Dydrogesterone 30 mg daily versus Crinone 8% intravaginal progesterone gel 90 mg daily ...
    Medical condition: Treatment for the luteal support in in-vitro fertilization (IVF).
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004865 10021572 In vitro fertilization LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021021-13 Sponsor Protocol Number: 10EU/HMG02 Start Date*: 2010-11-25
    Sponsor Name:IBSA, Institut Biochimique S.A.
    Full Title: Safety and efficacy study comparing a new hMG formulation (hMG-IBSA) to a reference product (Menopur®) in patients undergoing ovarian stimulation for in vitro fertilisation (IVF).
    Medical condition: Patients, with basal FSH <10 IU/L and E2 <80 pg/ml (~290 pmol/l), undergoing controlled ovarian stimulation for in vitro fertilisation.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10056204 In vitro fertilisation LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed) DK (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2012-004824-39 Sponsor Protocol Number: 1 Start Date*: 2015-09-18
    Sponsor Name:UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST
    Full Title: The use of GnRH antagonist versus co-flare protocol for women with low ovarian reserve undergoing first cycle of in vitro fertilization
    Medical condition: response to ovarian stimulation in women with reduced ovarian reserve undergoing first cycle of in vitro fertilisaion.
    Disease: Version SOC Term Classification Code Term Level
    17.0 10042613 - Surgical and medical procedures 10056204 In vitro fertilisation PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004460-31 Sponsor Protocol Number: PRINT Start Date*: 2007-02-21
    Sponsor Name:Guy's & St Thomas' NHS Foundation Trust
    Full Title: A randomised controlled trial comparing the gonadotrophin releasing hormone (GnRH) agonist long regimen versus the GnRH agonist short regimen versus the GnRH antagonist regimen in poor responders u...
    Medical condition: Poor ovarian response in women undergoing In vitro Fertilisation (IVF) treatment.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10056204 In vitro fertilisation PT
    Population Age: Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-017854-11 Sponsor Protocol Number: FIBHGM-ECNC004-2010(FEBRES-09) Start Date*: 2010-06-22
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital Gregorio Marañón
    Full Title: Efecto de la dosis de FSH recombinante en el resultado de la estimulación ovárica para fecundación in vitro en pacientes con baja reserva ovárica. Estudio aleatorizado y abierto de no inferioridad....
    Medical condition: Hiperestimulación ovárica controlada para inducir el desarrollo de folículos múltiples en programas de reproducción asistida
    Disease: Version SOC Term Classification Code Term Level
    9 10021572 In vitro fertilization LLT
    9 10021926 Infertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020559-29 Sponsor Protocol Number: IVF-03-01-052 Start Date*: 2010-09-23
    Sponsor Name:Pantec Biosolutions AG
    Full Title: Proof of concept study to investigate the efficacy, safety and tolerability as well as the pharmacokinetics and pharmacodynamics of a newly developed patch containing follicle-stimulating hormone a...
    Medical condition: Healthy female oocyte donors of normal body weight (body mass index within 18 to 29 kg/m2), age from 20 to 30 years (inclusive), ultrasound of ovaries, normal endocrine status, non-smoker
    Disease: Version SOC Term Classification Code Term Level
    12.0 10021926 Infertility LLT
    12.0 10056204 In vitro fertilisation LLT
    Population Age: Adults Gender: Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003938-41 Sponsor Protocol Number: IMP 28364 Start Date*: 2007-09-25
    Sponsor Name:Merck Lipha Santé SAS
    Full Title: Open label pilot study on gene expression profiling of the endometrial tissue in patients undergoing Assisted Reproductive Technology (ART: only IVF) with GONAL-f.
    Medical condition: This study will be conducted in infertile women justifying ART (Assisted Reproductive Technology) treatment (only IVF - In Vitro Fecondation)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056204 In vitro fertilisation LLT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2017-002267-18 Sponsor Protocol Number: APTE Start Date*: 2017-11-27
    Sponsor Name:Sara Rafael Fernández
    Full Title: EFFICACY AND SAFETY OF THE CONCENTRATE OF AUTOMOTIVE RICH PLASMA IN GROWTH FACTORS IN THE TREATMENT OF THE FINE ENDOMETRY IN PATIENTS SUBMITTED TO TRANSFER OF CRIO-PRESERVED EMBRYOS: CLINICAL TRIAL...
    Medical condition: infertile women
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10056204 In vitro fertilisation PT
    20.0 100000024038 10016463 Fertility decreased female LLT
    20.0 10038604 - Reproductive system and breast disorders 10021928 Infertility female PT
    20.0 10038604 - Reproductive system and breast disorders 10021926 Infertility PT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012121-11 Sponsor Protocol Number: P06060 (299001) Start Date*: 2009-10-13
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: A randomized, multicenter, explorative trial to explore the safety, acceptability and vaginal bleeding pattern of three doses of an etonogestrel-releasing medicated intrauterine system (ENG-MIUS) v...
    Medical condition: healthy parous women in need of contraception
    Disease: Version SOC Term Classification Code Term Level
    12.0 10010808 Contraception LLT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-002482-19 Sponsor Protocol Number: 13EU/FSH01 Start Date*: 2013-12-12
    Sponsor Name:IBSA Institut Biochimique S.A.
    Full Title: Randomised clinical trial comparing highly purified FSH formulation (Fostimon®) and recombinant FSH (Gonal-F®) in GnRH-antagonist controlled ovarian hyperstimulation cycles.
    Medical condition: female infertility
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004872 10016398 Female infertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed) GB (Completed) ES (Completed) BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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