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Clinical trials for Extubation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    141 result(s) found for: Extubation. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2016-003260-39 Sponsor Protocol Number: ML16633 Start Date*: 2016-08-05
    Sponsor Name:F. Hoffmann-La Roche AG
    Full Title: Intravenous Granisetron (Kytril) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy
    Medical condition: Prevention of Post-operative Nausea and Vomiting (PONV) in pediatric subjects
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-004389-15 Sponsor Protocol Number: STH14192 Start Date*: 2007-04-05
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: The use of Single dose intravenous paracetamol "Perfalgan" in Early extubation cardiac surgery
    Medical condition: Extubation time following coronary artery bypass surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000714-20 Sponsor Protocol Number: ASOKLIF 0511/JA Start Date*: 2006-04-18
    Sponsor Name:Dr. Wolfgang Jaksch
    Full Title: Klinische Studie zum Einfluss einer postoperativen Verabreichung von (S)-(+)-Ketamin auf das Schmerzempfinden nach großen chirurgischen Eingriffen
    Medical condition: Postoperatives Schmerzempfinden bei elektiven großen bauchchirurgischen Eingriffen, transabdominellen urologischen Eingriffe oder transabdominellen gynäkologischen Eingriffen
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000596-16 Sponsor Protocol Number: DH112018 Start Date*: 2019-04-17
    Sponsor Name:University Hospitals Leuven
    Full Title: Erector spinae plane block for minimal invasive direct coronary artery bypass surgery. A double blind, prospective randomized placebo-controlled trial.
    Medical condition: postoperative pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001125-27 Sponsor Protocol Number: DH022019 Start Date*: 2019-06-04
    Sponsor Name:University Hospitals Leuven
    Full Title: Erector Spinae plane block for minimal invasive mitral valve surgery. A double blind, prospective randomized placebo-controlled trial.
    Medical condition: postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2022-003202-77 Sponsor Protocol Number: NEOKOFF22 Start Date*: 2023-04-04
    Sponsor Name:
    Full Title: The effect of additional pre-extubational loading dose of caffeine-citrate
    Medical condition: Extubation failure and bronchopulmonary dysplasia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10002973 Apnea neonatal LLT
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10071132 Primary apnea of premature newborns LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10077322 Infantile apnea LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10077325 Infantile obstructive apnea LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10077328 Infantile central apnea LLT
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10028975 Neonatal respiratory failure PT
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10006475 Bronchopulmonary dysplasia PT
    20.0 100000004868 10076729 Very preterm infant LLT
    23.1 100000004868 10084217 Extremely preterm (less than 28 weeks) LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: HU (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-004351-20 Sponsor Protocol Number: 01122018v2 Start Date*: 2019-02-01
    Sponsor Name:Aarhus University Hospital
    Full Title: Intraoperative methadone in same-day hysterectomy: a prospective, double-blind, randomised controlled trial
    Medical condition: Same-day hysterectomy
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10023692 Laparoscopically assisted hysterectomy LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2022-002496-11 Sponsor Protocol Number: 07072022v1.0 Start Date*: 2022-10-03
    Sponsor Name:Aarhus University Hospital
    Full Title: METATONS - Intraoperative methadone for postoperative pain in patients undergoing tonsillectomy - a randomized controlled trial
    Medical condition: Same-day tonsillectomy
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002021-35 Sponsor Protocol Number: ANR-1/14 Start Date*: 2014-09-23
    Sponsor Name:Fondazione IRCCS Istituto Nazionale dei Tumori
    Full Title: Decurarization After Thoracic Anesthesia - A prospective multicenter double-blind randomized trial comparing sugammadex vs neostigmine reversal after thoracic anesthesia
    Medical condition: Neuromuscular block is commonly adopted during general anesthesia to facilitate tracheal intubation, mechanical ventilation and surgical manipulation. At the end of anesthesia it very important to ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005342-63 Sponsor Protocol Number: UoL001206 Start Date*: 2016-06-23
    Sponsor Name:University of Liverpool
    Full Title: Mindex: The efficacy and safety of very low dose dexamethasone used to facilitate the extubation of ventilator dependent preterm babies who are at high risk of bronchopulmonary dysplasia
    Medical condition: Bronchopulmonary dysplasia
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-003684-14 Sponsor Protocol Number: DH11/2022 Start Date*: 2023-03-01
    Sponsor Name:University Hospitals Leuven
    Full Title: Intrathecal morphine for minimally invasive direct coronary artery bypass surgery: a multicentre, double blind, prospective randomized placebo-controlled trial
    Medical condition: Postoperative pain treatment after robotically assisted minimally invasive direct coronary artery bypass surgery.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004826-47 Sponsor Protocol Number: 23956082 Start Date*: 2020-12-16
    Sponsor Name:Lone Nikolajsen
    Full Title: Intraoperative methadone for postoperative pain management in spinal fusion surgery: a prospective, double-blind, randomised controlled trial
    Medical condition: Low back pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-002672-13 Sponsor Protocol Number: CRHACS Start Date*: 2021-03-18
    Sponsor Name:ALMA MATER STUDIORUM UNIVERSITà DI BOLOGNA
    Full Title: CPAP Reduces Hypoxemia After Cardiac Surgery (CRHACS Trial). A randomized controlled trial
    Medical condition: Hypoxemia after cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10038738 Respiratory, thoracic and mediastinal disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011112-37 Sponsor Protocol Number: 2009-3 Start Date*: 2009-08-04
    Sponsor Name:Dept. of Anaesthesia, Oslo University Hospital, Ullevål
    Full Title: Dexmedetomidine versus midazolam til sedasjon av pediatriske intensivpasienter ved Oslo Universitetssykehus.
    Medical condition: Paediatric patients requiring mecanical ventilation and sedation in PICU.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003225-15 Sponsor Protocol Number: HALO-ICU Start Date*: 2017-12-19
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
    Full Title: Comparison between inhaled sedation with Sevoflurane vs endovenous sedation with Propofol in the Intensive Care Unit: a randomized prospective trial
    Medical condition: Preoperative-scheduled sedation in surgical patients admitted in the Intensive Care Unit (ICU) for postoperative monitoring
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10049124 Sedation during medical procedure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001650-98 Sponsor Protocol Number: AC1802 Start Date*: 2018-12-10
    Sponsor Name:University of Edinburgh and NHS Lothian [...]
    1. University of Edinburgh and NHS Lothian
    2. NHS Lothian
    Full Title: Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): A randomised, parallel-group, allocation concealed, controlled, open, phase 3 pragmatic clinical and cost...
    Medical condition: Any patient requiring intensive care treatment due to critical illness.
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10033305 Oversedation LLT
    20.0 10029205 - Nervous system disorders 10039897 Sedation PT
    21.1 100000004865 10049124 Sedation during medical procedure LLT
    20.1 10029205 - Nervous system disorders 10039898 Sedation excessive LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-004581-18 Sponsor Protocol Number: 26123332 Start Date*: 2020-03-12
    Sponsor Name:Lone Nikolajsen
    Full Title: Clinical effectiveness and safety of intraoperative methadone in patients undergoing cystectomy: a randomised, double-blind trial
    Medical condition: Bladder cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10005003 Bladder cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002411-26 Sponsor Protocol Number: GO-SLEEP Start Date*: 2019-10-09
    Sponsor Name:CHU de Poitiers
    Full Title: Impact of Gamma-OH on sleep in ICU patients difficult to wean from mechanical ventilation
    Medical condition: Patients difficult to wean from mechanical ventilation in the ICU
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10067221 Mechanical ventilation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-001425-48 Sponsor Protocol Number: BLUEBERRY Start Date*: 2021-07-07
    Sponsor Name:Division of Anaesthesiology - Department of Acute Medicine - Geneva Children's Hospital, University Hospitals of Geneva
    Full Title: Dexamethasone and postoperative bleeding following tonsillectomy in children
    Medical condition: Tonsillectomy/tonsillotomy
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-002258-56 Sponsor Protocol Number: SD-DXP Start Date*: 2018-08-27
    Sponsor Name:University Hospitals Leuven
    Full Title: The use of xenon and dexmedetomidine for the prevention of postoperative emergence delirium after anaesthesia for pediatric cardiac catheterization: A randomized, controlled, observer-blinded pilot...
    Medical condition: xenon-dexmedetomidine Anesthesia in children undergoing cardiac catheterization
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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