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Clinical trials for Generalized seizures

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    150 result(s) found for: Generalized seizures. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2011-000265-12 Sponsor Protocol Number: E2007-G000-332 Start Date*: 2011-08-31
    Sponsor Name:Eisai Limited
    Full Title: A Double-blind, Randomized, Placebo-controlled, Multicenter, Parallel-group Study with an Open-label Extension Phase to Evaluate the Efficacy and Safety of Adjunctive Perampanel in Primary Generali...
    Medical condition: Primary Generalized Tonic-Clonic Seizures
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10018101 Generalised tonic-clonic seizures HLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) LV (Completed) GR (Completed) AT (Completed) CZ (Completed) NL (Completed) PL (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001337-41 Sponsor Protocol Number: YKP3089C025 Start Date*: 2018-12-17
    Sponsor Name:SK Life Science, Inc.
    Full Title: A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Cenobamate Adjunctive Therapy in Subjects with Primary Generalized Tonic-Clonic Seizures
    Medical condition: Primary Generalized Tonic-Clonic Seizures
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10018101 Generalised tonic-clonic seizures HLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Trial now transitioned) BG (Completed) CZ (Completed) SK (Trial now transitioned) PL (Trial now transitioned) DE (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003100-21 Sponsor Protocol Number: SP0982 Start Date*: 2015-10-02
    Sponsor Name:UCB BIOSCIENCES, Inc.
    Full Title: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, PARALLEL-GROUP, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF LACOSAMIDE AS ADJUNCTIVE THERAPY FOR UNCONTROLLED PRIMARY GENERALIZED TONIC-...
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10071096 Idiopathic generalized epilepsy LLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) SK (Completed) HU (Completed) DE (Completed) ES (Completed) CZ (Completed) BE (Completed) IT (Completed) PL (Completed) FR (Completed) BG (Completed) RO (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2017-001180-20 Sponsor Protocol Number: E2007-G000-410 Start Date*: 2021-10-28
    Sponsor Name:Eisai Inc.
    Full Title: Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Genera...
    Medical condition: Epilepsy: Partial Onset Seizures with or without 1) Secondarily Generalized Seizures 2) Primary Generalized Tonic-Clonic Seizures
    Disease: Version SOC Term Classification Code Term Level
    24.0 10029205 - Nervous system disorders 10085326 Parietal lobe epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-006695-10 Sponsor Protocol Number: E2090-E044-316 Start Date*: 2008-09-23
    Sponsor Name:Eisai Limited
    Full Title: Open Label Extension Study Following Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess Efficacy and Safety of Adjunctive Zonisamide in Primary Generalized Tonic-Clonic Seizures
    Medical condition: Primary generalised tonic-clonic seizures (PGTCS) in idiopathic generalised epilepsy (IGE)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018101 Generalised tonic-clonic seizures HLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-002981-37 Sponsor Protocol Number: YKP3089C033 Start Date*: 2019-08-23
    Sponsor Name:SK Life Science, Inc.
    Full Title: A Multicenter Open-label Extension Study to Evaluate the Long-term Safety of Cenobamate Adjunctive Therapy in Subjects with Primary Generalized Tonic-Clonic Seizures
    Medical condition: Primary Generalized Tonic-Clonic Seizures
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10018101 Generalised tonic-clonic seizures HLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Trial now transitioned) PL (Trial now transitioned) CZ (Completed) BG (Completed) DE (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004401-32 Sponsor Protocol Number: N01159 Start Date*: 2015-03-02
    Sponsor Name:UCB Japan Co. Ltd.
    Full Title: A Double-blind, Multicenter, Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of Adjunctive Treatment With Oral Levetiracetam, in Epilepsy Patients Aged ≥16 Years, With Gene...
    Medical condition: - Epilepsy - Generalized Tonic-Clonic Seizures
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-001997-13 Sponsor Protocol Number: N167 Start Date*: 2004-11-22
    Sponsor Name:UCB S.A. Pharma Sector
    Full Title: An open-label, multicenter, follow-up study to evaluate the safety and efficacy of levetiracetam (LEV) (oral tablets of 166, 250 or 500 mg b.i.d.), at individualized doses up to a maximum of 4000 m...
    Medical condition: Neurology, epilepsy, primary generalized seizures
    Disease: Version SOC Term Classification Code Term Level
    10018079 LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002167-16 Sponsor Protocol Number: E2007-G000-311 Start Date*: 2017-01-30
    Sponsor Name:Eisai Limited
    Full Title: An Open-Label, Multicenter Study with an Extension Phase to Evaluate the Safety, Tolerability, and Exposure-Efficacy Relationship of Perampanel Oral Suspension when Administered as an Adjunctive Th...
    Medical condition: Epilepsy : 1) Partial-Onset Seizures (POS) 2) Primary Generalized Tonic-Clonic Seizures (PGTC)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10018101 Generalised tonic-clonic seizures HLT
    19.0 10029205 - Nervous system disorders 10061334 Partial seizures PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) LV (Completed) ES (Completed) PL (Completed) BE (Completed) IT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2013-003771-35 Sponsor Protocol Number: UX007G-CL201 Start Date*: 2014-02-11
    Sponsor Name:Ultragenyx Pharmaceutical Inc
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Adaptive Study to Assess the Safety and Efficacy of UX007 in Subjects with Glucose Transporter Type 1 Deficiency Syndrome
    Medical condition: Glucose Transporter Type 1 deficiency syndrome
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10039911 Seizures (incl subtypes) HLGT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed) GB (Completed) FR (Ongoing) HU (Completed) ES (Completed) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003557-91 Sponsor Protocol Number: E2090-E044-315 Start Date*: 2008-07-09
    Sponsor Name:Eisai Limited
    Full Title: A double-blind, randomised, placebo-controlled, multicentre study to assess the efficacy and safety of adjunctive zonisamide in primary generalised tonic clonic seizures
    Medical condition: Primary generalised tonic-clonic seizures (PGTCS) in idiopathic generalised epilepsy (IGE)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018101 Generalised tonic-clonic seizures HLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed) HU (Prematurely Ended) LT (Prematurely Ended) FI (Prematurely Ended) CZ (Prematurely Ended) EE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-004382-25 Sponsor Protocol Number: N01363 Start Date*: 2015-02-24
    Sponsor Name:UCB Japan Co. Ltd.
    Full Title: An Open-label, Single-arm, Multicenter Study to Evaluate the Efficacy and Safety of Adjunctive Treatment With Levetiracetam in Japanese Patients (≥4 to <16 Years) With Uncontrolled Generalized Toni...
    Medical condition: - Epilepsy - Generalized Tonic-clonic Seizures
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2018-002484-25 Sponsor Protocol Number: TAK-935-2002(OV935) Start Date*: 2019-04-29
    Sponsor Name:Takeda Development Center Americas, Inc.
    Full Title: A PHASE 2, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY, SAFETY, AND TOLERABILITY OF TAK-935 (OV935) AS AN ADJUNCTIVE THERAPY IN PEDIATRIC PATIENTS WITH ...
    Medical condition: Epileptic Encephalitis: Dravet and Lennox Gastuat syndrome (LGS)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: PT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2004-000199-14 Sponsor Protocol Number: N01009 Start Date*: 2004-11-25
    Sponsor Name:UCB Pharma S.A. [...]
    1. UCB Pharma S.A.
    2. UCB Pharma Inc.
    Full Title: A double-blind, randomized, multicenter, placebo-controlled, in-patients maximum 34 day study of levetiracetam oral solution (20-50 mg/kg/day) as adjunctive treatment of refractory partial onset se...
    Medical condition: Epilepsy - Refractory Partial Onset Seizures
    Disease: Version SOC Term Classification Code Term Level
    7.0 10061334 LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) BE (Completed) HU (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-003734-17 Sponsor Protocol Number: E2007-J000-342 Start Date*: 2019-11-22
    Sponsor Name:Eisai Co., Ltd. (Japan)
    Full Title: A Multicenter, Uncontrolled, Open-label Study and Extension Study for Verification of Efficacy and Safety for Perampanel Monotherapy in Untreated Patients with Partial Onset Seizures (Including Sec...
    Medical condition: Epilepsy : 1) Partial-Onset Seizures (POS)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2021-001959-13 Sponsor Protocol Number: EPICDKL5 Start Date*: 2021-12-02
    Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
    Full Title: Adjunctive cannabidiol therapy in patients with CDKL5 deficiency disorder. Interventional drug study on efficacy and safety with focus on seizure effects
    Medical condition: patients with CDKL5
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10015039 Epilepsy congenital PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000125-13 Sponsor Protocol Number: B3541002 Start Date*: 2017-01-12
    Sponsor Name:Pfizer Inc
    Full Title: A Multi-center, Open-label, Non-controlled Study To Evaluate The Efficacy And Safety Of Lorazepam Intravenously Administered In Subjects With Status Epilepticus Or Repetitive Status Epilepticus
    Medical condition: Status Epilepticus
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-004023-19 Sponsor Protocol Number: A0081046 Start Date*: 2006-05-25
    Sponsor Name:Pfizer Ltd, Ramsgate Rd, Sandwich, Kent, United Kingdom
    Full Title: A RANDOMIZED, COMPARATIVE, DOUBLE-BLIND, PARALLEL-GROUP, MULTICENTER, MONOTHERAPY, STUDY OF PREGABALIN (LYRICA) AND LAMOTRIGINE (LAMICTAL) IN PATIENTS WITH NEWLY DIAGNOSED PARTIAL SEIZURES
    Medical condition: Epilepsy; Patients with newly diagnosed partial seizures (with or without secondary generalization)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061334 Partial seizures LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) PT (Completed) ES (Completed) BE (Completed) IE (Completed) CZ (Completed) LT (Completed) DE (Completed) SK (Completed) IT (Completed) HU (Completed) FI (Completed) EE (Completed) BG (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2005-001982-33 Sponsor Protocol Number: E2090-E044-401 Start Date*: 2005-09-05
    Sponsor Name:Eisai Limited
    Full Title: An open label study of Zonegran (zonisamide) in patients with partial onset seizures.
    Medical condition: Indicated as adjunctive therapy in the treatment of adult patients with partial seizures, with or without secondary generalisation.
    Disease: Version SOC Term Classification Code Term Level
    8.0 10061334 pt
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) AT (Completed) SE (Completed) DK (Completed) FI (Completed) DE (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-004951-55 Sponsor Protocol Number: E2090-AS086-311 Start Date*: 2017-04-24
    Sponsor Name:Eisai Inc.
    Full Title: A Multicenter, Placebo-controlled, Double-blind Study to Evaluate the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizures
    Medical condition: Epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
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