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Clinical trials for Glaucoma

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    221 result(s) found for: Glaucoma. Displaying page 1 of 12.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2010-020213-82 Sponsor Protocol Number: GLC-04-10 Start Date*: 2010-05-27
    Sponsor Name:IRCCS- FONDAZIONE G.B. BIETTI PER LO STUDIO E LA RICERCA IN OFTALMOLOGIA-ONLUS
    Full Title: Comparison of Incidence and Severity of conjunctival hyperemia associated with use of topical Bimatoprost 0.01% and latanoprost 0.005% in Glaucoma or Ocular Hypertensive patients
    Medical condition: glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018304 LLT
    9.1 10018304 LLT
    9.1 10018304 LLT
    9.1 10018304 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-002601-30 Sponsor Protocol Number: QTM/OMN0111 Start Date*: 2011-09-26
    Sponsor Name:OMNIVISION GmbH
    Full Title: A COMPARISON OF LATANOPROST 50µg/ml EYE DROPS vs. XALATAN EYE DROPS IN THE TREATMENT OF OPEN ANGLE GLAUCOMA: AN OPEN, RANDOMIZED, CLINICAL TRIAL
    Medical condition: Open angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10030856 Open-angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-001733-41 Sponsor Protocol Number: 004,1 Start Date*: 2013-06-12
    Sponsor Name:Harju Mika
    Full Title: Hypertonic saline - the effect of repeating doses
    Medical condition: Elevated eyepressure
    Disease: Version SOC Term Classification Code Term Level
    16.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    16.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2010-022586-10 Sponsor Protocol Number: SCO 5511 Start Date*: 2011-05-05
    Sponsor Name:Alfred E. Tiefenbacher (GmbH & Co. KG)
    Full Title: Randomized, Double-Masked, Active Controlled, Crossover Phase III Equivalence Study of Travoprost Eye Drops Solution in Subjects with Open Angle Glaucoma or Ocular Hypertension
    Medical condition: Open Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    13.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-009182-34 Sponsor Protocol Number: DOR/2008 Start Date*: 2009-03-30
    Sponsor Name:ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Full Title: RANDOMIZED, DOUBLE MASKED; ACTIVE CONTROLLED, CROSSOVER PHASE III EQUIVALENCE STUDY OF DORZOLAMIDE 2 % EYE DROPS SOLUTION IN SUBJECTS WITH OPEN ANGLE GLAUCOMA OR OCULAR HYPERTENSION
    Medical condition: Open angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-024272-26 Sponsor Protocol Number: GLC-05-10 Start Date*: 2011-04-14
    Sponsor Name:IRCCS- FONDAZIONE G.B. BIETTI PER LO STUDIO E LA RICERCA IN OFTALMOLOGIA-ONLUS
    Full Title: Comparison of the effects of Bimatoprost 0.01% and Timolol 0.5% on circadian intraocular pressure
    Medical condition: glaucoma and ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001786-34 Sponsor Protocol Number: IT-04-01 Start Date*: 2005-05-16
    Sponsor Name:ALCON ITALIA
    Full Title: Hypotonic efficacy and tollerability of Travoprost in patient with open angle primary glaucoma and/or ocular hypertension, not controlled with dorzolamide + timolol treatment in fixed association...
    Medical condition: Reducing high intraocular pressure in patient with ocular hypertension or open-angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    6.1 10030348 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-018853-36 Sponsor Protocol Number: Cos_Gan_PR/09 Start Date*: 2010-09-04
    Sponsor Name:Prof. Stefano Gandolfi-Universita` degli studi di Parma
    Full Title: Switching from beta blocker monotherapy to either ganfort � or cosopt �. A three months, single-blind , parallel group, randomized clinical trial in ocular hypertension/primary open angle glaucoma.
    Medical condition: Primary open angle glaucoma or ocular hypertensive patients, any level of intraocular pressure.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-006005-61 Sponsor Protocol Number: PRN 05-001 Start Date*: 2006-03-16
    Sponsor Name:Pharmaceutical Research Network, LLC
    Full Title: A COMPARISON OF THE EFFICACY AND SAFETY OF THE DORZOLAMIDE/TIMOLOL FIXED COMBINATION GIVEN TWICE DAILY VERSUS THE LATANOPROST/TIMOLOL FIXED COMBINATION GIVEN ONCE EVERY MORNING FOLLOWING A RUN-IN...
    Medical condition: open-angle glaucoma ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    10030348
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010101-36 Sponsor Protocol Number: Alcon SMA-08-22 Start Date*: 2009-09-21
    Sponsor Name:Alcon Laboratories, Inc.
    Full Title: The Efficacy and Safety of Adding the Brinzolamide/Timolol Maleate Fixed Combination (Azarga®) to Prostaglandin Monotherapy
    Medical condition: primary open-angle glaucoma ocular hypertension pigment dispersion glaucoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10035015 Pigmentary glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    9.1 10036719 Primary open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-022984-36 Sponsor Protocol Number: 201051 Start Date*: Information not available in EudraCT
    Sponsor Name:Santen Oy
    Full Title: A phase III, randomized, double-masked 6-month clinical study to compare the efficacy and safety of the preservative-free fixed dose combination of tafluprost 0.0015% and timolol 0.5% eye drops to ...
    Medical condition: Patients diagnosed with ocular hypertension or open-angle glaucoma (primary open-angle glaucoma [POAG], capsular glaucoma or pigmentary glaucoma).
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030043 Ocular hypertension LLT
    12.1 10036719 Primary open angle glaucoma LLT
    12.1 10035015 Pigmentary glaucoma LLT
    12.1 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LV (Completed) CZ (Completed) ES (Completed) PT (Completed) AT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2012-000044-10 Sponsor Protocol Number: QTM/OMN0114 Start Date*: 2015-03-30
    Sponsor Name:OMNIVISION
    Full Title: Open, Observer-blind, two Parallel Group, Randomized, Multicentric Clinical Phase III Trial on the Comparison of Efficacy and Tolerability of a New Preservative-free Formulation of the Fixed Combin...
    Medical condition: Open Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    18.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    18.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-005273-37 Sponsor Protocol Number: 201450 Start Date*: 2015-02-17
    Sponsor Name:Santen Oy
    Full Title: A phase IV study on the changes in ocular signs and symptoms in patients with ocular hypertension or open-angle glaucoma switched from Ganfort® eye drops (bimatoprost 0.03%/timolol 0.5%) to Taptiq...
    Medical condition: Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    17.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    17.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    17.1 10015919 - Eye disorders 10074026 Exfoliation glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022965-82 Sponsor Protocol Number: 201050 Start Date*: 2010-12-22
    Sponsor Name:Santen Oy
    Full Title: A phase III, randomized, double-masked 6-month clinical study to compare the efficacy and safety of the preservative-free fixed-dose combination of tafluprost 0.0015% and timolol 0.5% eye drops to ...
    Medical condition: Ocular hypertension and POAG, capsular glaucoma and pigmentary glaucoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10035015 Pigmentary glaucoma PT
    14.1 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.1 10015919 - Eye disorders 10036719 Primary open angle glaucoma LLT
    14.1 10015919 - Eye disorders 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) DE (Completed) EE (Completed) NL (Completed) PL (Completed) IT (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020746-98 Sponsor Protocol Number: 77557 Start Date*: 2010-11-01
    Sponsor Name:Santen Oy
    Full Title: An open-label phase IV study on the changes in ocular signs and symptoms in patients with ocular hypertension or open-angle glaucoma switched from preserved travoprost 0.004% eye drops to preservat...
    Medical condition: Patients diagnosed with Ocular Hypertension or Open-angle glaucoma (primary open-angle glaucoma [POAG] or capsular glaucoma)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030856 Open-angle glaucoma LLT
    12.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021039-14 Sponsor Protocol Number: S001-2010 Start Date*: 2010-08-19
    Sponsor Name:Tampere University, Faculty of Medicine, Department of Ophthalmology
    Full Title: An open-label, phase IV, pilot study, to evaluate confocal microscopic findings of cornea, ocular signs and symptoms in patients with ocular hypertension or open-angle glaucoma switching from latan...
    Medical condition: Ocular Hypertension (OH) or Open-Angle Glaucoma (OAG); primary open-angle glaucoma [POAG] or capsular glaucoma.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030043 Ocular hypertension LLT
    12.1 10030856 Open-angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002131-18 Sponsor Protocol Number: 192024-093 Start Date*: 2016-12-21
    Sponsor Name:Allergan Limited
    Full Title: A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-angle Glaucoma and Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) DK (Completed) PL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2010-022948-21 Sponsor Protocol Number: RDG-10-246 Start Date*: 2011-03-08
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Eficacia y Seguridad de añadir Brinzolamida/Maleato de Timolol en combinación fija (Azarga ®) en pacientes con Hipertensión ocular o Glaucoma no controlados en Monoterapia de Prostaglandinas
    Medical condition: Hipertension ocular o glaucoma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030856 Open-angle glaucoma LLT
    12.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-002501-45 Sponsor Protocol Number: EMD-06-02 Start Date*: 2008-03-14
    Sponsor Name:Alcon Laboratories Inc.
    Full Title: Phase IV randomised double masked clinical trial: Assessing morning versus evening dosing of a fixed dose combination of Travoprost 0.004% / Timolol Maleate 0.5% in patients with primary open angle...
    Medical condition: Open - angle glaucoma or ocular hypertension.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-003083-31 Sponsor Protocol Number: Becro/OV/Brimo Start Date*: 2013-10-17
    Sponsor Name:OmniVision GmbH
    Full Title: Open, Observer-blind, two Parallel Group, Randomized, Multicentric Clinical Phase III Trial on the Comparison of Efficacy and Tolerability of a New Preservative-free Formulation of Brimonidine 2 mg...
    Medical condition: Open angle glaucoma or ocular hypertension.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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