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Clinical trials for Hydrochloride

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    2,828 result(s) found for: Hydrochloride. Displaying page 1 of 142.
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    EudraCT Number: 2006-000858-45 Sponsor Protocol Number: S308.3.006 Start Date*: 2006-12-18
    Sponsor Name:Solvay Pharmaceuticals
    Full Title: An open label SLV308 safety extension to study S308.3.001 in early PD patients.
    Medical condition: Parkinson's Disease Early Stage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SK (Completed) SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-006033-32 Sponsor Protocol Number: S308.3.001 Start Date*: 2006-04-20
    Sponsor Name:Solvay Pharmaceuticals
    Full Title: A Randomized, Double-blind, Placebo Controlled Parallel-group Fixed and Flexible SLV308 Dose Arm Study to Assess Efficacy and Safety of SLV308 Monotherapy in the Treatment of Patients with Early St...
    Medical condition: Parkinson's Disease Early Stage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SK (Completed) SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005183-91 Sponsor Protocol Number: S308.3.007 Start Date*: 2007-02-14
    Sponsor Name:Solvay Pharmaceuticals
    Full Title: An open label SLV308 safety extension to study S308.3.002 in patients with Parkinson’s disease experiencing motor fluctuations.
    Medical condition: Advanced stage Parkinson's disease with motor fluctuations.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013113 Disease Parkinson's LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002229-23 Sponsor Protocol Number: RB-UK-11-0018 Start Date*: 2012-05-09
    Sponsor Name:RB Pharmaceuticals Inc.
    Full Title: A randomised, double blind, placebo controlled, cross over study of the effects of Buprenorphine Hemiadipate Hydrochloride/Naloxone Hydrochloride Dihydrate intravenous challenges in opioid dependen...
    Medical condition: Maintenance/substitution agent for the treatment of opioid dependence.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10012346 Dependence on opiates LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002432-10 Sponsor Protocol Number: S308.3.005 Start Date*: 2005-11-25
    Sponsor Name:Solvay Pharmaceuticals
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, ascending dose, parallel group study exploring effects of SLV308 up to 42 mg/day administered as an adjunctive therapy to l-dopa in pati...
    Medical condition: Parkinson Disease late stage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: MT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-016079-32 Sponsor Protocol Number: AS Start Date*: 2010-12-02
    Sponsor Name:Universitätsklinik für Psychiatrie - Spezialambulanz für Abhangigkeitserkrankungen
    Full Title: Auswirkungen der Substitutionstherapie mit Methadon und Buprenorphin auf die kognitiven Funktionen.
    Medical condition: Untersuchung der kognitiven Leistungsfähigkeit bei Opiatabhängigen, die sich in der Substitutionstherapie unter Methadon und unter Buprenorphin befinden.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012814-36 Sponsor Protocol Number: HDL09-01 Start Date*: 2009-09-23
    Sponsor Name:Helsingin Diakonissalaitos
    Full Title: Buprenorfiini-naloksoni ja metadoni erilaisissa psykososiaalisissa hoito-ohjelmissa buprenorfiiniriippuvaisten korvaushoidossa. Satunnaistettu kontrolloitu tutkimus
    Medical condition: Opioidiriippuvuus, buptenorfiinin suonensisäinen väärinkäyttö
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030893 Opioid type dependence, continuous use LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-010428-25 Sponsor Protocol Number: KF5503/45 Start Date*: 2010-02-15
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with severe chronic nocicept...
    Medical condition: Low back Pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) NL (Completed) DE (Completed) FR (Completed) BE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-000859-18 Sponsor Protocol Number: S308.3.008 Start Date*: 2006-09-11
    Sponsor Name:Solvay Pharmaceuticals
    Full Title: An open label SLV308 safety extension to study S308.3.003 in early PD patients
    Medical condition: Parkinson's Disease Early stage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) EE (Completed) LT (Completed) PT (Completed) IT (Completed) DE (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-003280-38 Sponsor Protocol Number: PSY-NIL-0006 Start Date*: 2016-05-04
    Sponsor Name:Medical University of Vienna
    Full Title: Positron Emission Tomography assessment of Ketamine Binding of the Serotonin Transporter and its Relevance for Rapid Antidepressant Response
    Medical condition: 20 patients with severe unipolar depression (structured clinical interview for DSM-IV and the 17-item Hamilton Depression Rating Scale), also 20 age and sex matched healthy controls. plus 12 HC f...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004873 10045543 Unipolar depression LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-003925-23 Sponsor Protocol Number: PIANISSIMO Start Date*: 2023-04-12
    Sponsor Name:Vrije Universiteit Brussel
    Full Title: Pain medication tapering for patients with Persistent Spinal Pain Syndrome Type II, treated with Spinal Cord Stimulation.
    Medical condition: Persistent spinal pain syndrome type 2
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-005182-20 Sponsor Protocol Number: S308.3.002 Start Date*: 2007-02-13
    Sponsor Name:Solvay Pharmaceuticals
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, parallel group study of SLV308 as adjunct therapy to levodopa in patients with Parkinson’s disease experiencing motor fluctuations.
    Medical condition: Advanced stage Parkinson's disease with motor fluctuations.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10034007 Parkinson's disease NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014518-83 Sponsor Protocol Number: C_21060_P3_04 Start Date*: 2009-10-07
    Sponsor Name:Acino Supply AG
    Full Title: A double blind, two-period cross-over study to compare the analgesic efficacy and tolerability of a new modified release formulation of hydromorphone (Hydromorphone hydrochloride 8 mg, 16 mg, and 2...
    Medical condition: chronic, severe pain adequately treated with Palladon® retard 8 mg or more twice daily
    Disease: Version SOC Term Classification Code Term Level
    12.0 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017470-20 Sponsor Protocol Number: GRT-CG5503-2009-02-FR Start Date*: 2010-05-07
    Sponsor Name:Laboratoires Grünenthal
    Full Title: An open-label extension study for patients with severe chronic low back pain or severe chronic pain due to knee osteoarthritis who have completed any of the previous phase IIIb trials with tapentad...
    Medical condition: Severe chronic pain
    Disease: Version SOC Term Classification Code Term Level
    12.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-010423-58 Sponsor Protocol Number: KF5503/42 Start Date*: 2009-08-28
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with uncontrolled severe chr...
    Medical condition: Pain due to Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-010425-39 Sponsor Protocol Number: KF5503/43 Start Date*: 2009-09-23
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with severe chronic pain due...
    Medical condition: Pain due to Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) DE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-013022-16 Sponsor Protocol Number: ZonMw 80-82100-98-096/11510014 Start Date*: 2009-10-21
    Sponsor Name:Erasmus MC [...]
    1. Erasmus MC
    2. ZonMw
    Full Title: Effecten en bijwerkingen van opioïden: een studie naar de rol van farmacokinetische en farmacogenetische heterogeniteit.
    Medical condition: Nociceptive cancer pain for which strong opioids are needed
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058019 Cancer pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014982-16 Sponsor Protocol Number: DIA002 Start Date*: 2010-02-25
    Sponsor Name:Wockhardt UK Limited
    Full Title: An open label, single dose safety study of Diamorphine Hydrochloride Nasal Spray (0.1mg/kg) in children
    Medical condition: The IMP is to be used as an analgesic for the relief of acute pain.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10002182 Analgesia LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-001313-42 Sponsor Protocol Number: OXN2001 (Inc. Amd 3) Start Date*: 2007-11-02
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A randomised, double-blind, active-controlled, double-dummy, parallel group study to determine the safety and efficacy of oxycodone / naloxone prolonged release tablets in subjects with moderate to...
    Medical condition: subjects with moderate to severe, chronic cancer pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058019 Cancer pain LLT
    9.1 10058019 Cancer pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) DE (Completed) HU (Completed) FR (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-002235-26 Sponsor Protocol Number: OTR3002 Start Date*: 2011-10-26
    Sponsor Name:Purdue Pharma L.P.
    Full Title: An Open-label, Extension Study to Assess the Long-Term Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Opioid Experienced Children Who Completed the OTR3001 Study
    Medical condition: Opioid experienced paediatric patients aged 6-17 years with moderate to severe malignant and/or nonmalignant pain requiring opioid therapy.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10002182 Analgesia LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) EE (Completed) ES (Completed) FI (Completed) DE (Completed) GR (Prematurely Ended) GB (Prematurely Ended) SK (Completed) BE (Completed) HU (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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