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Clinical trials for INR

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,382 result(s) found for: INR. Displaying page 1 of 70.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2010-022826-34 Sponsor Protocol Number: 08092010 Start Date*: 2011-04-28
    Sponsor Name:
    Full Title: Randomised trial to investigate possible differences in biological availability and effectiveness between vitamin K solution in oil and vitamin K tablets.
    Medical condition: Lowering anticoagulant effect of vitamin K antagonists in case of over-anticoagulation or pending diagnostic or therapeutic invase action.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10053755 Vitamin K antagonist LLT
    12.1 10058768 Vitamin K LLT
    12.1 10011970 Decreased INR LLT
    12.1 10037818 Raised INR LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003432-30 Sponsor Protocol Number: P051056 Start Date*: 2007-09-14
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Interaction médicamenteuse entre la warfarine (Coumadine®) et l’association amoxicilline-acide clavulanique (Augmentin®)
    Medical condition: maladies thromboemboliques
    Disease: Version SOC Term Classification Code Term Level
    8.1 10043607 thrombose PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002291-41 Sponsor Protocol Number: 1 Start Date*: 2018-08-30
    Sponsor Name:Gelderse Vallei Hospital
    Full Title: The effect of administering VITamin K preprocedural on the vitamin K dependent coagulation factors and the INR in patients anticoagulated with ACEnocoumarol
    Medical condition: Adult patients using acenocoumarol and planned to undergo an invasive procedure for which the effect of the anticoagulants should be reversed.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001007-18 Sponsor Protocol Number: 2989 Start Date*: 2005-06-03
    Sponsor Name:Royal Victoria Infirmary
    Full Title: Reversal of warfarin anticoagulation with oral vitamin K: towards a better management of over-anticoagulation
    Medical condition: Patients with thromboembolic disorders are anticogulated with warfarin. However excessive over-anticoagulation can increase the patient risk of bleeding. Oral vitamin K is routinely used for revers...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006416-30 Sponsor Protocol Number: INPAWA 2 Start Date*: 2006-12-28
    Sponsor Name:Unité de Recherches Thérapeutiques
    Full Title: Effect of two distinct dosing regimen of acetaminophen on the anticoagulant effect of warfarin
    Medical condition: Arterial and venous thromboembolic disease including atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    8.1 10043565 Thromboembolic event LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000382-19 Sponsor Protocol Number: BE1116_3001 Start Date*: 2005-09-15
    Sponsor Name:ZLB Behring GmbH
    Full Title: Efficacy and tolerance of BERIPLEX® P/N in subjects with acquired deficiency of coagulation factors II, VII, IX and X due to oral anticoagulation
    Medical condition: Acquired deficiency of coagulation factors II, VII, IX and X due to oral anticoagulation requiring an immediate reversal of anticoagulant effect (i.e. emergency surgery or acute bleeding).
    Disease: Version SOC Term Classification Code Term Level
    7.1 10000534 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) HU (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003086-25 Sponsor Protocol Number: 201600620 Start Date*: 2017-04-19
    Sponsor Name:University Medical Center Groningen
    Full Title: More precise dosing of acenocoumarol in patients aged 80 and above, a pilot study
    Medical condition: atrial fibrillation venous thrombo-embolism heart valve repair other diseases with an indication for anticoagulation with vitamin K antagonists
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007862-39 Sponsor Protocol Number: BE1116_3003 Start Date*: 2009-01-16
    Sponsor Name:CSL Behring GmbH
    Full Title: An open-label, randomized, multicenter Phase IIIb study to assess the efficacy, safety and tolerance of BERIPLEX® P/N compared with plasma for rapid reversal of coagulopathy induced by vitamin K an...
    Medical condition: Perioperative prophylaxis for emergency surgery in subjects who have an acquired deficiency of vitamin K-dependent coagulation factors and proteins C and S
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10065667 Haemorrhage prophylaxis PT
    14.1 100000004848 10009789 Coagulation factors decreased LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed) PL (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-007861-19 Sponsor Protocol Number: BE1116_3002 Start Date*: 2009-01-16
    Sponsor Name:CSL Behring GmbH
    Full Title: An open-label, randomized, multicenter Phase IIIb study to assess the efficacy, safety and tolerance of BERIPLEX® P/N compared with plasma for rapid reversal of coagulopathy induced by coumarin der...
    Medical condition: Therapy of major bleeding resulting from an acquired deficiency of vitamin K-dependent coagulation factors and proteins C and S due to use of oral anticoagulation therapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009789 Coagulation factors decreased LLT
    9.1 10005103 Bleeding LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-016992-31 Sponsor Protocol Number: COU-001A Start Date*: 2010-03-19
    Sponsor Name:Democritus Universityof Thrace Medical School [...]
    1. Democritus Universityof Thrace Medical School
    2. University Utrecht
    3. Fundacion Marques de Valdecilla
    Full Title: EUropean Pharmacogenetics of AntiCoagulation Therapy trial
    Medical condition: Newly diagnosed patients with venous tromboembolism (VTE) or atrial fibrillation (AF) requiring oral anticoagulation with phenprocoumon.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003658 Atrial fibrillation LLT
    12.1 10012107 Deep venous thrombosis NOS LLT
    12.1 10037377 Pulmonary embolism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016993-34 Sponsor Protocol Number: COU-001W Start Date*: 2010-09-02
    Sponsor Name:Uppsala University Hospital
    Full Title: EUropean Pharmacogenetics of AntiCoagulation Therapy trial
    Medical condition: Newly diagnosed patients with venous tromboembolism (VTE) or atrial fibrillation (AF) requiring oral anticoagulation with warfarin.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    14.1 10047065 - Vascular disorders 10012107 Deep venous thrombosis NOS LLT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10037377 Pulmonary embolism PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016994-13 Sponsor Protocol Number: COU-001P Start Date*: 2010-03-19
    Sponsor Name:University Utrecht [...]
    1. University Utrecht
    2. Prof. Dr. R Marre, University Hospital Ulm
    3. Elisabethinen Hospital Linz
    Full Title: EUropean Pharmacogenetics of AntiCoagulation Therapy trial
    Medical condition: Newly diagnosed patients with venous tromboembolism (VTE) or atrial fibrillation (AF) requiring oral anticoagulation with phenprocoumon.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10003658 Atrial fibrillation LLT
    12.0 10012107 Deep venous thrombosis NOS LLT
    12.0 10037377 Pulmonary embolism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002536-94 Sponsor Protocol Number: 1160.47 Start Date*: 2006-03-20
    Sponsor Name:Boehringer Ingelheim Finland Ky
    Full Title: A phase III, randomised, multicenter, double-blind, parallel-group, active controlled study to evaluate the efficacy and safety of oral dabigatran etexilate (150 mg bid) compared to warfarin (INR 2...
    Medical condition: Confirmed Venous Thromboembolism (VTE) i.e. uni or bilateral deep vein thrombosis (DVT) of the leg involving proximal veins and/or pulmonay embolism (PE) - treated with anticoagulant for 3 to 6 mo...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) AT (Completed) SE (Completed) CZ (Completed) BE (Completed) SK (Completed) GB (Completed) ES (Completed) DE (Completed) HU (Completed) PT (Completed) GR (Completed) DK (Completed) IT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2007-005037-11 Sponsor Protocol Number: WP21272 Start Date*: 2008-01-02
    Sponsor Name:F.Hoffmann-La Roche Ltd
    Full Title: An open-label, randomized 2-period crossover study to investigate the pharmacodynamics, pharmacokinetics, safety and tolerability of warfarin in combination with oseltamivir in volunteers stabilize...
    Medical condition: Drug interaction study to investigate the the PD, PK, safety and tolerability of warfarin in combination with oseltamivir in volunteers stabilized on warfarin therapy.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-015858-38 Sponsor Protocol Number: ACENO-K-01-2009 Start Date*: 2011-05-26
    Sponsor Name:Dr. Antonio Javier Trujillo Santos
    Full Title: Comparación de la adición de bajas dosis de vitamina K al tratamiento con acenocumarol frente al tratamiento tradicional con acenocumarol sobre la estabilidad del efecto anticoagulante y sus compli...
    Medical condition: Pacientes que precisen de anticoagulación oral con cumarinas durante al menos 3 meses, fundamentalmente son pacientes con arritmias cardíacas (sobre todo fibrilación auricular) y enfermedad tromboe...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016643-18 Sponsor Protocol Number: FC/HULP_002 Start Date*: 2010-03-18
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital Universitario de La Paz
    Full Title: Ensayo clínico randomizado para evaluar la eficiencia y efectividad de la dosificación individualizada de acenocumarol mediante un algoritmo farmacogenético versus ajuste estándar en pacientes que...
    Medical condition: enfermedad tromboembólica venosa (ETEV: trombosis venosa profunda y tromboembolismo pulmonar).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000030-11 Sponsor Protocol Number: NAC400 Start Date*: 2011-04-07
    Sponsor Name:INSTITUTO DE INVESTIGACIÓN SANITARIA LA FE
    Full Title: EFICACIA DE N-ACETILCISTEINA EN EL LÍQUIDO DE PRESERVACIÓN DURANTE EL TRASPLANTE HEPÁTICO
    Medical condition: Trasplante hepático
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006238-87 Sponsor Protocol Number: 4717 Start Date*: 2010-01-22
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: Improving the safety and efficacy of anticoagulation therapy for thromboembolic disease through vitamin K
    Medical condition: Patients will be recruited who are receiving long term warfarin therapy for the treatment or prevention of venous or arterial thrombosis or embolism
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-001639-35 Sponsor Protocol Number: M602011014 Start Date*: 2019-11-26
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: Prospective, randomized, double-blind, placebo-controlled, multicenter study to investigate the efficacy and safety of NT 201 in the treatment of lower limb spasticity caused by stroke or traumatic...
    Medical condition: Diagnosis of lower limb spasticity with or without upper limb spasticity of the same body side caused by stroke or traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10058977 Spastic paresis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned) DE (Trial now transitioned) FR (Trial now transitioned) NO (Completed) CZ (Trial now transitioned) GB (GB - no longer in EU/EEA) ES (Ongoing) IT (Trial now transitioned) HU (Trial now transitioned) SK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-004975-37 Sponsor Protocol Number: LIMIT Start Date*: 2021-09-06
    Sponsor Name:Hamilton Health Sciences through the Population Health Research Institute
    Full Title: Low INR to Minimize bleeding with mechanical valves Trial
    Medical condition: Treatment with a Vitamin K Antagonist due to having a mechanical heart valve.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
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