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Clinical trials for Immunodeficiency

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    753 result(s) found for: Immunodeficiency. Displaying page 1 of 38.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2005-000669-21 Sponsor Protocol Number: ML18243 Start Date*: 2005-04-26
    Sponsor Name:ROCHE
    Full Title: Pilot study of HIV Viral slope in naive patients treated with Enfuvirtide (ENF) based therapy compared to current standard treatment.
    Medical condition: advanced HIV management
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000565 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-006522-25 Sponsor Protocol Number: ZLB06_005CR Start Date*: 2007-02-01
    Sponsor Name:CSL Behring AG
    Full Title: A multicenter study on the efficacy and safety of Vivaglobin® in Previously Untreated Patients (PUPs) with Primary Immunodeficiency (PID)
    Medical condition: Patients with PID diseases as Common Variable Immunodeficiency (CVID) or X-linked agammaglobulinemia ( XLA), age 1 to 70 years
    Disease: Version SOC Term Classification Code Term Level
    8.1 10010112 Common variable immunodeficiency LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Prematurely Ended) BE (Completed) GR (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-007882-19 Sponsor Protocol Number: MI2-STAR2-2006 Start Date*: 2006-10-09
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: A pilot, randomized trial to evaluate the lipid profile after antiretroviral regimens including nevirapine or atazanavir boosted with ritonavir in HIV-positive patients naive for antiretrovirals
    Medical condition: immunodefic syndrome - patients naive antiretroviral therapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000565 Acquired immunodeficiency syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-007934-21 Sponsor Protocol Number: MI2-INCA-2007 Start Date*: 2007-06-27
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: Intracellular concentration of Antiretrovirals)INCA STADY
    Medical condition: HIV -immunodefic syndrome-
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000565 Acquired immunodeficiency syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006188-35 Sponsor Protocol Number: IMMUNEF Start Date*: 2009-01-29
    Sponsor Name:AZIENDA OSPEDALIERA SAN GERARDO DI MONZA
    Full Title: Immunological efficacy of efavirenz based treatment in HIV-positive naive patients (a pylot study)
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052740 Acquired immunodeficiency syndromes HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002818-38 Sponsor Protocol Number: ML 19326 Start Date*: 2005-07-21
    Sponsor Name:ROCHE
    Full Title: ESPrES 500 - Evaluation of the safety profile of the new 500 mg film-coated tablet (FCT) formulation of boosted saquinavir (Invirase 500 mg) in HIV-1 infected patients
    Medical condition: HIV-! / AIDS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000565 Acquired immunodeficiency syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-002437-13 Sponsor Protocol Number: TMC114-C226 Start Date*: 2006-05-09
    Sponsor Name:Tibotec Pharmaceuticals Ltd.
    Full Title: Early access of TMC114 in combination with low-dose ritonavir (RTV) and other antiretrovirals (ARVs) in highly treatment experienced HIV-1 infected subjects with limited to no treatment options.
    Medical condition: HIV-1 infected patient
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-001681-16 Sponsor Protocol Number: Break Start Date*: 2006-06-06
    Sponsor Name:FONDAZIONE NADIR ONLUS
    Full Title: A pilot, open label, randomised clinical trial assessing the 12 week immunological response in HIV-1 failing subjects receiving monotherapy with emtricitabine 200 mg once a day or emtricitabine 200...
    Medical condition: HIV-Infection
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000565 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004646-29 Sponsor Protocol Number: GESIDA9016 Start Date*: 2017-05-31
    Sponsor Name:Fundación SEIMC-GESIDA
    Full Title: A phase IV open- label, randomized and pilot clinical trial, designed to evaluate the potential neurotoxicity of dolutegravir/lamivudine/abacavir in neurosymptomatic HIV patients and their reversi...
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004862 10001509 AIDS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001621-26 Sponsor Protocol Number: MALINFITA006 Start Date*: 2006-03-13
    Sponsor Name:A.U.S.L. RIMINI
    Full Title: A RANDOMIZED, MULTICENTER STUDY OF USE INTERMITTENT HAART HIGHLY ACTIVE ANTIRETROVIRAL THERAPY THERAPY VERSUS CONTINUATIVE HAART THERAPY IN HIV PATIENTS
    Medical condition: PATIENTS POSITIVE HIV TO LOW RISK OF DEVELOPMENT OF OPPORTUNISTIC PATHOLOGIES CORRELATED-HIV.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10052740 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-007935-14 Sponsor Protocol Number: MI2-RIFART-2005 Start Date*: 2005-03-15
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: RIFART
    Medical condition: HIV- TB
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000565 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-002582-39 Sponsor Protocol Number: NADIR-02 Start Date*: 2006-07-10
    Sponsor Name:FONDAZIONE NADIR ONLUS
    Full Title: A multicenter, randomized, prospective, controlled study to evaluate the efficacy and the tolerability of a switch to a two different-dosed, nevirapine-based HAARTs in HIV-1 infected patients with ...
    Medical condition: pazienti HIV-1 positivi
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000565 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019518-25 Sponsor Protocol Number: MENHIR Start Date*: 2010-06-11
    Sponsor Name:AZIENDA OSPEDALIERA "OSPEDALI RIUNITI DI BERGAMO" (A.O. DI RILIEVO NAZIONALE)
    Full Title: (Maraviroc ENHancement of Immunological Response): A pilot study of maraviroc as an add-on in patients with reduced CD4 cell count despite full viral suppression
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052740 HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000307-26 Sponsor Protocol Number: CeTMAd-VIH-2014 Start Date*: 2016-06-09
    Sponsor Name:Iniciativa Andaluza en Terapias Avanzadas-Fundación Pública Andaluza Progreso y Salud
    Full Title: Clinical trial Phase I/II, test of concept, double blind, randomized, controlled with placebo, to evalue the safety and efficiency of the treatment with expanded adult mesenchymal stem cells from a...
    Medical condition: Infection for HIV with controlled viral load and immunological discordant response
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004862 10001509 AIDS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2018-001158-82 Sponsor Protocol Number: GESIDA10418 Start Date*: 2018-09-21
    Sponsor Name:Fundación SEIMC-GESIDA
    Full Title: Phase IV, Open Label, Randomized, Clinical Trial to Evaluate the Reversibility of abacavir/lamivudine/dolutegravir CNS-Related Neurotoxicity After Switching to tenofovir alafenamide/emtricitabine/d...
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10001509 AIDS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2008-008556-16 Sponsor Protocol Number: PRADA Start Date*: 2009-07-13
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Pharmacokinetic and safety study of RAltegravir and atazanavir in a once DAily dose regimen in HIV-1 in-fected patients (PRADA)
    Medical condition: HIV infected patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000390-59 Sponsor Protocol Number: P03802 Start Date*: 2004-07-15
    Sponsor Name:SCHERING-PLOUGH
    Full Title: Safety and efficacy of SCH 417690 in HIV-infected treatment-naive subjects
    Medical condition: HIV-1 infected naive subject
    Disease: Version SOC Term Classification Code Term Level
    6.1 10020161 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-003463-31 Sponsor Protocol Number: P04999 Start Date*: 2010-08-23
    Sponsor Name:Schering-Plough Research Institute
    Full Title: COVER- Registro de observación continua tras exposición Vicriviroc (VCV)
    Medical condition: Síndrome de inmunodeficiencia adquirida (SIDA)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    9.1 10020161 HIV infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000240-94 Sponsor Protocol Number: CLEAR0001 Start Date*: 2012-05-09
    Sponsor Name:Aarhus University Hospital
    Full Title: The Safety and Efficacy of The Histone Deacetylase Inhibitor Panobinostat for Purging HIV-1 from The Latent Reservoir (CLEAR) Study
    Medical condition: Human Immunodeficiency Virus (HIV) Infection
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10020172 HIV infection NOS LLT
    14.1 10021881 - Infections and infestations 10020192 HIV-1 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2022-001591-33 Sponsor Protocol Number: DoRSwitch.21 Start Date*: 2022-10-06
    Sponsor Name:Fundació Clinic per a la Recerca Biomèdica
    Full Title: Open-label, single-arm, unicenter and Pilot Study of a Switch strategy from Etravirine (ETR) to Doravirine (DOR) in Virologically-Suppressed HIV-1 Infected Adults With ETR-Resistance
    Medical condition: Human Immunodeficiency Virus (HIV)
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10020161 HIV infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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