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Clinical trials for Implants

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44379   clinical trials with a EudraCT protocol, of which   7391   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,054 result(s) found for: Implants. Displaying page 1 of 53.
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    EudraCT Number: 2020-006142-39 Sponsor Protocol Number: ATB21 Start Date*: 2021-08-13
    Sponsor Name:Facultad de Odontología. Universidad Complutense de Madrid
    Full Title: INFLUENCE OF THE ANTIBIOTIC GUIDELINE ON IMPLANT SURVIVAL
    Medical condition: Patients undergoing implant placement
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002532-16 Sponsor Protocol Number: 02 Start Date*: 2017-12-05
    Sponsor Name:Cliniques Universitaires Saint-Luc
    Full Title: Adjunctive systemic antimicrobial therapy in the surgical treatment of peri-implantitis. A prospective randomized clinical study
    Medical condition: To treat patients with chronic infection of dental implants. One group with antibiotics and one group without.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004878-26 Sponsor Protocol Number: 26842468452 Start Date*: 2013-02-07
    Sponsor Name:Karolinska University Hospital Solna
    Full Title: Antibiotic prophylaxis in patients undergoing primary or secondary breast reconstruction with implants, a randomized parallel two armed prospective clinical trial.
    Medical condition: The incidence of postoperative infections in patients with breast cancer or a history of breast cancer, after elective surgery with primary or secondary first-time breast reconstruction with implan...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Prohibited by CA)
    Trial results: (No results available)
    EudraCT Number: 2006-003551-20 Sponsor Protocol Number: 2006-MSC-01 Start Date*: 2007-06-25
    Sponsor Name:Department of Oral Surgery Dental School Med. Univ. Graz, Austria
    Full Title: The Effect of adult MSC on Bone Regeneration and Osseointegration of Dental Implants following a Sinus Augmentation Procedure
    Medical condition: In patients with biltareral edentulous areas and resorbed alveolar processes in the maxilla a bilateral sinus augmentation with Bio-OssTM, CE certified (Geistlich Biomaterials, Wolhusen Switzerlan...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-002112-41 Sponsor Protocol Number: 2016-05-04 Start Date*: 2016-07-16
    Sponsor Name:Region Östergötland
    Full Title: Can Insuline improve the healing of dental implants?
    Medical condition: Missing teeth
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004825-42 Sponsor Protocol Number: Notapplicablenow Start Date*: 2016-12-22
    Sponsor Name:ACTA
    Full Title: Effect of Delmopinol on treatment of Peri - implant mucositis : a randomised controlled clinical trial
    Medical condition: Peri implant mucositis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2018-004046-41 Sponsor Protocol Number: 273551 Start Date*: 2021-12-09
    Sponsor Name:University of Bergen,
    Full Title: A multicentre clinical trial; Alveolar bone augmentation using Mesenchymal Stem Cells and biphasic calcium phosphate granules prior to dental implants
    Medical condition: Patients in need of dental implant(s) in the upper and lower jaws with presence of bone defects with loss in vertical height and < than 4 mm in lateral width
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003940-21 Sponsor Protocol Number: 46361 Start Date*: 2014-03-20
    Sponsor Name:University Medical Center Groningen
    Full Title: Systemic antibiotic therapy (amoxicillin plus metronidazole) as an adjunct to surgical treatment of peri-implantitis; a single blind randomized controlled study
    Medical condition: peri-implantitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002181-20 Sponsor Protocol Number: NTX2010-2-0130 Start Date*: 2011-12-29
    Sponsor Name:Oslo University Hospital [...]
    1. Oslo University Hospital
    2. Oslo University Hospital
    Full Title: Naltrexone Implants for Alcoholism
    Medical condition: Alcohol dependence in outpatients.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10001640 Alcoholism (excl psychosis) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000276-15 Sponsor Protocol Number: OV-AP-ICG-IV Start Date*: 2013-03-08
    Sponsor Name:Jules Bordet Institute
    Full Title: Feasibility study of the (intravenously injected) Indocyanine green (ICG) imaging of tumoral implants in patients with peritoneal carcinomatosis from ovarian carcinoma
    Medical condition: Peritoneal carcinomatosis from ovarian cancer
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000024-34 Sponsor Protocol Number: CH-MAX-FACC-TR-12 Start Date*: 2015-01-13
    Sponsor Name:AOU di Bologna, Policlinico S.Orsola-Malpighi
    Full Title: Use of PRP from umbilical cord in post-extractive sites
    Medical condition: • Patients who require extraction of dental elements and subsequent implant rehabilitation in the same site.
    Disease: Version SOC Term Classification Code Term Level
    17.0 10028395 - Musculoskeletal and connective tissue disorders 10068975 Bone atrophy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003512-37 Sponsor Protocol Number: OC-AP-ICG-IV-2 Start Date*: 2014-10-13
    Sponsor Name:Jules Bordet Institute
    Full Title: Study of the (intravenously injected) ICG (Indocyanine Green) imaging of tumoral implants in patients with peritoneal carcinomatosis from colorectal origin.
    Medical condition: Imaging of tumours and their metastasis after intravenous injection of Indocyanine Green to patients with peritoneal carcinomatosis from colorectal cancer.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000653-42 Sponsor Protocol Number: OC-AP-ICG-IV Start Date*: 2013-03-20
    Sponsor Name:Jules Bordet Institute
    Full Title: Feasibility study of the (intravenously injected) ICG imaging of tumoral implants in patients with peritoneal carcinomatosis from colorectal cancer
    Medical condition: Peritoneal carcinomatosis from colon Cancer.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001848-35 Sponsor Protocol Number: APB-MET-2017-01 Start Date*: 2017-12-14
    Sponsor Name:Juan Blanco Carrion
    Full Title: METRONIDAZOLE AS AN ADJUNCT OF NON-SURGICAL TREATMENT OF PERI-IMPLANTITIS: A 6-MONTHS PLACEBO-CONTROLLED CLINICAL TRIAL IN HUMANS.
    Medical condition: Peri-implantitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000636-13 Sponsor Protocol Number: CUV017 Start Date*: 2008-06-17
    Sponsor Name:Clinuvel Pharmaceuticals Limited
    Full Title: A Phase III, Multicentre, Randomised, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Bioresorbable CUV1647 Implants in Patients with Erythropoietic Protoporphyria (EPP)
    Medical condition: Erythropoietic Protoporphyria (EPP)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015289 Erythropoietic protoporphyria LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) IT (Completed) FR (Completed) DE (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2020-004564-26 Sponsor Protocol Number: BAS20 Start Date*: 2021-09-20
    Sponsor Name:Karolinska Institute
    Full Title: Role of antibiotics in conjunction with oral bone augmentation procedures (BAS20)
    Medical condition: Patients requiring bone augmentation procedure prior to, or in conjunction to installation of dental implants.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10049924 Infection prophylaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-002459-40 Sponsor Protocol Number: BREAST-AB-01 Start Date*: 2020-12-17
    Sponsor Name:Rigshospitalet
    Full Title: Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: a randomized controlled trial (The ...
    Medical condition: Implant-based breast reconstruction following mastectomy
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-001481-18 Sponsor Protocol Number: 6925 Start Date*: 2011-10-07
    Sponsor Name:Uppsala University Hospital
    Full Title: Uncemented total hip implant and subcutaneous injection of Denosumab for patients with osteoarthritis of the hip. A randomised double blind placebo controlled study on the effects on bone evaluated...
    Medical condition: Patients with osteoarthritis of the hip treated with an uncemented total hip arthroplasty. This procedure is accompanied with an increased risk for loss of bone adjacent to the implants
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004356-20 Sponsor Protocol Number: DCS-002 Start Date*: 2011-10-31
    Sponsor Name:Pergamum AB
    Full Title: A randomised, parallel-group, double-blind, placebo-controlled study of DPK-060 to investigate clinical safety and efficacy in patients with acute external otitis
    Medical condition: Acute external otitis (EO)
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-001885-40 Sponsor Protocol Number: Syst-AB+Sinus Start Date*: 2022-02-24
    Sponsor Name:Universidad Complutense de Madrid
    Full Title: The effect of systemic antibiotics on post-surgical complications and paitent-centered outomes in patients undergoing implant surgery with the guided bone regeneration and simultaneous sinus floor ...
    Medical condition: The medical condition that the patients have in this trial is edentulism in a posterior maxillary quadrant of the mouth with a sinus pneumatisation/ decreased crestal bone heigh defect requiring a...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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