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Clinical trials for Insulin sensitivity

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    345 result(s) found for: Insulin sensitivity. Displaying page 1 of 18.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2011-006165-18 Sponsor Protocol Number: FEN Start Date*: 2012-06-20
    Sponsor Name:Academic Medical Center
    Full Title: A randomized double blind placebo controlled study on the effects of fenretinide Lym-X-Sorb on insulin sensitivity in obese insulin resistant subjects
    Medical condition: Obesity Metabolic syndrome X Insulin resistance Fatty liver
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003124-73 Sponsor Protocol Number: na Start Date*: 2018-01-31
    Sponsor Name:Maastricht University
    Full Title: Carnitine supplementation as a therapy to improve insulin sensitivity in Type 2 diabetic patients with low carnitine status
    Medical condition: Glucose tolerance
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-003771-19 Sponsor Protocol Number: 2019-100 Start Date*: 2019-11-19
    Sponsor Name:Aarhus Universitetshospital
    Full Title: The effect of improved insulin sensitivity on bone turnover markers and bone biomechanical properties in persons with type 2 diabetes mellitus
    Medical condition: Type 2 diabetes mellitus Diabetic bone disease
    Disease: Version SOC Term Classification Code Term Level
    21.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-001356-36 Sponsor Protocol Number: 20131 Start Date*: 2013-10-10
    Sponsor Name:"G. d'Annunzio" University
    Full Title: Effects of liraglutide or lifestyle counselling on subcutaneous adipose tissue and visceral adipose tissue distribution, circulating adipokine concentration, insulin sensitivity and beta-cell perfo...
    Medical condition: Obesity with a diagnosis of impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) or type 2 Diabetes Mellitus (T2DM) for less than 12 months, according to the American Diabetes Associa...
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000810-31 Sponsor Protocol Number: na Start Date*: 2016-07-08
    Sponsor Name:Maastricht University
    Full Title: Impact of L-Carnitine infusion on Lipid induced Insulin resistance
    Medical condition: Glucose tolerance
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-003477-18 Sponsor Protocol Number: Empabrain01 Start Date*: 2017-05-04
    Sponsor Name:University Hospital Tuebingen
    Full Title: A double-blind randomized study to determine the effect of empagliflozin versus placebo on brain insulin sensitivity in patients with prediabetes
    Medical condition: brain insulin sensitivity in patients with prediabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004861 10065542 Prediabetes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002880-86 Sponsor Protocol Number: 936 Start Date*: 2013-01-25
    Sponsor Name:Liverpool Heart and Chest Hospital NHS Trust
    Full Title: PRESERVING ΒETA-CELLS: ‘RESTING THE PANCREAS’ IN CYSTIC FIBROSIS
    Medical condition: Cystic Fibrosis Related Diabetes (CFRD)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004848 10022468 Insulin LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-002964-22 Sponsor Protocol Number: AGO/2013/009 Start Date*: 2013-12-10
    Sponsor Name:Ghent University Hospital
    Full Title: Influence of aromatase inhibitors on insulin sensitivity, liver and hart function in obese men
    Medical condition: Influence of aromatase inhibitors on insulin sensitivity, liver and hart function in obese men
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002649-39 Sponsor Protocol Number: WC28038 Start Date*: 2012-11-15
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: A SINGLE-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE II STUDY TO ASSESS THE EFFICACY OF ALEGLITAZAR ON INSULIN SENSITIVITY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS (T2D) WHO ARE IN...
    Medical condition: Type II Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004861 10063624 Type II diabetes mellitus inadequate control LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-000086-35 Sponsor Protocol Number: NN304-1430 Start Date*: 2004-11-01
    Sponsor Name:Novo Nordisk Farma Oy
    Full Title: A one-year, multi-national, open-labelled, parallel-group, 2:1 randomised treat-to-target trial comparing efficacy and safety of insulin detemir with insulin glargine using a basal-bolus regimen wi...
    Medical condition: Type 1 diabetes
    Disease: Version SOC Term Classification Code Term Level
    7.0 10012608 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2012-003011-58 Sponsor Protocol Number: CACZ885M2301S2 Start Date*: 2012-12-10
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, double-blind, placebo-controlled, event-driven trial of quarterly subcutaneous canakinumab in the prevention of recurrent cardiovascular events among stable post-myocardial infarction...
    Medical condition: atherosclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) HU (Completed) IT (Prematurely Ended) SK (Completed)
    Trial results: View results
    EudraCT Number: 2009-010999-19 Sponsor Protocol Number: MEC-2009-074 Start Date*: 2010-07-07
    Sponsor Name:Erasmus MC - Sophia Children's Hospital
    Full Title: Protein and Energy Interactions in Critically Ill Children
    Medical condition: We want to study protein, glucose and lipid metabolism in critically ill septic children admitted to the PICU. As these children often receive insulin because of hyperglycemia due to insulin resist...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022489 Insulin resistance LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-003991-27 Sponsor Protocol Number: D1690C00047 Start Date*: 2017-12-27
    Sponsor Name:AstraZeneca AB
    Full Title: MAAST: A Double-blind, Randomized, Phase IV, Mechanistic, Placebo-controlled, Cross-over, Single-center Study to Evaluate the Effects of 5 Weeks Dapagliflozin Treatment on Insulin Sensitivity in Sk...
    Medical condition: Study to investigate mitochondrial function and insulin sensitivity in skeletal muscle in subjects with T2DM.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-023479-24 Sponsor Protocol Number: 01/2010 Start Date*: 2011-02-03
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Effect of Interleukin-1 receptor antagonist on insulin sensitivity in subjects with type 1 diabetes mellitus.
    Medical condition: diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012601 Diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-016783-37 Sponsor Protocol Number: WS475202 Start Date*: 2010-01-07
    Sponsor Name:Sahlgrenska University Hospital
    Full Title: The Effects of 18-Month Replacement with a Very Low Fixed Dose vs. Standard Dose of Growth Hormone (GH) on Insulin Sensitivity, Body Composition, Bone Mass, Lipids, Muscle Strength and Quality of L...
    Medical condition: Growth hormone deficiency in adults
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000022-63 Sponsor Protocol Number: 1-10-72-393-12 Start Date*: 2013-03-15
    Sponsor Name:Aarhus University
    Full Title: Acyl and desacyl ghrelin: The Yin and Yang of glucose homeostasis and insulin sensitivity? -Acute metabolic effects of desacyl ghrelin in insulin resistant patients
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    16.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-001663-22 Sponsor Protocol Number: na Start Date*: 2018-09-05
    Sponsor Name:Maastricht University
    Full Title: Effects of ciprofibrate on myocardial insulin sensitivity in pre-diabetes
    Medical condition: Insulin resistance, diastolic cardiac failure, mitochondrial function
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023980-17 Sponsor Protocol Number: Metformin 3.0 Start Date*: 2011-08-24
    Sponsor Name:St. Antonius Hospital
    Full Title: An efficacy, safety and pharmacokinetic study on the short-term and long-term use of METFORMIN in obese children and adolescents
    Medical condition: obese children and adolescents of Caucasian descent with insulin resistance in the age of ≥ 10 and ≤ 16 years at study entry.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000225-51 Sponsor Protocol Number: ITP-NODAT Start Date*: 2012-11-21
    Sponsor Name:Fundació Institut Mar d'investigacions Mediques
    Full Title: Insulin Therapy for the Prevention of New Onset Diabetes after Transplantation (ITP-NODAT) Prospective Study in Non-Diabetic De Novo Kidney Transplant Recipients
    Medical condition: Previously non-diabetic end stage renal disease patients undergoing kidney transplantation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001214-40 Sponsor Protocol Number: cro085 Start Date*: 2007-08-17
    Sponsor Name:Imperial College London
    Full Title: A trial to compare the effects of nebivolol versus atenolol on various cardiovascular measurements including insulin sensitivity
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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