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Clinical trials for Intraocular

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44294   clinical trials with a EudraCT protocol, of which   7351   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    413 result(s) found for: Intraocular. Displaying page 1 of 21.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2007-001046-41 Sponsor Protocol Number: 07OY004 Start Date*: 2008-12-11
    Sponsor Name:Nottingham University Hospital NHS Trust (Research & Development)
    Full Title: Effectiveness of GANfort® in reducing intraocular pressure in patients presenting with significantly elevated intraocular pressure
    Medical condition: Primary Open Angle Glaucoma Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022806 Intraocular pressure increased PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2012-005025-70 Sponsor Protocol Number: 003,1 Start Date*: 2012-12-21
    Sponsor Name:Helsingin Yliopistollinen keskussairaala
    Full Title: Reducing high intraocular pressure with hypertonic saline infusion before eyesurgery
    Medical condition: Elevated eyepressure
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004848 10022805 Intraocular pressure high LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2006-003907-38 Sponsor Protocol Number: DNB-001-CT001 Start Date*: 2007-03-06
    Sponsor Name:Danube Pharmaceuticals Inc.
    Full Title: A Multi-Centre, Double-Blind, Randomised, Parallel-Group, Placebo Controlled Phase II Study to Investigate the Safety, Efficacy, and Pharmacokinetic Profile of Twice-daily DNB-001 in Previously Unt...
    Medical condition: Intraocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    8.1 10021667 Increased intraocular pressure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001793-21 Sponsor Protocol Number: CPA12001 Start Date*: 2013-08-06
    Sponsor Name:PHARMATHEN S.A.
    Full Title: Efficacy and tolerability of brinzolamide in patients with elevated intraocular pressure: a double-blind, randomized, parallel, verum-controlled trial.
    Medical condition: intraocular pressure increased
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10022806 Intraocular pressure increased PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2013-002947-27 Sponsor Protocol Number: SYL040012_IV Start Date*: 2014-07-01
    Sponsor Name:Sylentis S.A.U.
    Full Title: A phase II, observer masked, active controlled study of SYL040012 for the treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension (SYLTAG)
    Medical condition: Open angle glaucoma - intraocular pressure
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004848 10022801 Intraocular pressure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2020-000252-35 Sponsor Protocol Number: DA-TCS-AD Start Date*: 2020-07-09
    Sponsor Name:Lone Skov
    Full Title: The risk of an elevated intraocular pressure after treatment with topical corticosteroids in the periocular region
    Medical condition: Intraocular pressure in healthy individuals and in patients with atopic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004858 10003639 Atopic dermatitis LLT
    20.1 100000004848 10022801 Intraocular pressure LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000225-36 Sponsor Protocol Number: hss198 Start Date*: 2015-05-20
    Sponsor Name:Helsinki University Hospital
    Full Title: PBA (4-phenylbutyrate) in the prevention of intraocular pressure increase caused by glucocorticoids
    Medical condition: Intraocular pressure increase caused by glucocorticoid use in genetically predisposed patients
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020932-20 Sponsor Protocol Number: D4250C00001 Start Date*: 2010-10-05
    Sponsor Name:AstraZeneca AB
    Full Title: A Double Masked, Placebo Controlled, Randomised, Parallel Group Phase IIa Study to assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-Ocular Pressure
    Medical condition: Raised Intra-Ocular Pressure or primary open angle glaucoma (POAG) on anti-glaucoma monotherapy that has been stable in dose for at least 30 days prior to screening.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10036719 Primary open angle glaucoma LLT
    14.1 10022891 - Investigations 10022809 Intraocular pressure raised LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001849-33 Sponsor Protocol Number: SYL040012_III Start Date*: 2012-04-09
    Sponsor Name:Sylentis S.A.U.
    Full Title: DOSE FINDING CLINICAL TRIAL WITH SYL040012 TO EVALUATE THE TOLERABILITY AND EFFECT ON INTRAOCULAR PRESSURE IN SUBJECTS WITH OCULAR HYPERTENSION OR OPEN-ANGLE GLAUCOMA
    Medical condition: Ocular Hypertension or Open-Angle Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10022801 Intraocular pressure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) ES (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-003164-50 Sponsor Protocol Number: CEUSUM Start Date*: 2012-10-19
    Sponsor Name:OSPEDALE S. RAFFAELE DI MILANO
    Full Title: CONTRAST ENHANCED ULTRASOUND (CEUS) IN UVEAL MELANOMA: QUANTITATIVE ASSESSMENT OF TUMOR RESPONSE TO GAMMA KNIFE RADIOSURGERY (GKR)
    Medical condition: patients affected by uveal melanoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061252 Intraocular melanoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-003157-16 Sponsor Protocol Number: OPHT-260213 Start Date*: 2013-08-27
    Sponsor Name:Ordination Dr. Hommer
    Full Title: An open, non-randomized study on the effect of preservative free tafluprost (Saflutan® Augentropfen) in patients with ocular hypertension or with primary open angle glaucoma with an uncontrolled in...
    Medical condition: Glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-006728-20 Sponsor Protocol Number: TAYS1002 Start Date*: 2007-05-31
    Sponsor Name:Moorfields Eye Hospital
    Full Title: The use of intraocular methotrexate to treat uveitis: a safety and efficacy study
    Medical condition: Uveitis (inflammatory eye disease)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10046851 Uveitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-004466-34 Sponsor Protocol Number: 005,1 Start Date*: 2014-02-25
    Sponsor Name:Hyks Silmätautien klinikka
    Full Title: The effect of hypertonic saline on blood electrolytes, acid-base balance and hormones that regulate blood pressure
    Medical condition: Elevated intraocular pressure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004201-29 Sponsor Protocol Number: CM-05-08/HU Start Date*: 2006-06-01
    Sponsor Name:Alcon Hungarian ltd
    Full Title: THE EFFICACY AND SAFETY OF TIMOLOL MALEATE 0.5% COMPARED TO BRINZOLAMIDE 1% EACH GIVEN TWICE DAILY WHEN ADDED TO TRAVOPROST 0.004% GIVEN EACH EVENING IN PRIMARY OPEN-ANGLE GLAUCOMA OR OCULAR HYPERT...
    Medical condition: Increased intraocular pressure and glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003885-15 Sponsor Protocol Number: OMS302-ILR-006 Start Date*: 2014-01-06
    Sponsor Name:Omeros Corporation
    Full Title: A Phase 3 Randomised, Double-Masked, Placebo-Controlled Study of the Effect of OMS302 on Intraoperative Pupil Diameter in Subjects at High Risk of Intraoperative Floppy Iris Syndrome Undergoing Int...
    Medical condition: Intraocular Lens Replacement (ILR) in subject at high risk for Intraoperative Floppy Iris Syndrome (IFIS)
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10054771 Intraocular lens replacement LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Prematurely Ended) AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-000867-25 Sponsor Protocol Number: OMS302-ILR-004 Start Date*: 2012-07-23
    Sponsor Name:Omeros Corporation
    Full Title: A Phase 3 Randomised, Double-Masked, Placebo-Controlled Study of the Pharmacokinetics of OMS302 and the Effect of OMS302 on Intraoperative Pupil Diameter and Early Postoperative Pain in Subjects Un...
    Medical condition: Intraocular Lens Replacement with Pharmacoemulsification
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004865 10054771 Intraocular lens replacement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-015916-16 Sponsor Protocol Number: 2.707/03/2010 Start Date*: 2009-11-06
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust
    Full Title: A Comparison of Postural and Ibopamine Challenges between Progressive and Non-Progressive Glaucoma Patients
    Medical condition: Glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001489-24 Sponsor Protocol Number: PSt012015 Start Date*: 2015-11-19
    Sponsor Name:Pharma Stulln GmbH
    Full Title: Prospective, controlled, randomized, investigator-masked, mul-ticenter, phase III trial to demonstrate the efficacy and safety of Brimonidine UD
    Medical condition: open angle glaucoma, elevated intraocular pressure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-003407-34 Sponsor Protocol Number: pre-CIN Start Date*: 2021-06-01
    Sponsor Name:Oslo University Hospital
    Full Title: A randomized clinical three-arm trial comparing inflammation and cystoid macular edema for the medication regimens preoperative and postoperative topical NSAIDs to only postoperative topical NSAIDs...
    Medical condition: Cataract surgery, and the medical treatment is anti-inflammatory eye drops to treat (and prevent) intraocular inflammation and development og cystoid macular edema.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-002777-27 Sponsor Protocol Number: CF101-231GL Start Date*: 2011-12-30
    Sponsor Name:Can-Fite BioPharma Ltd.
    Full Title: A Phase 2, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group Study of the Safety and Efficacy of Daily CF101 Administered Orally in Subjects with Elevated Intraocular Pressure
    Medical condition: patients with elevate intraocular pressure
    Disease: Version SOC Term Classification Code Term Level
    18.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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