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Clinical trials for Keratoconjunctivitis sicca

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    9 result(s) found for: Keratoconjunctivitis sicca. Displaying page 1 of 1.
    EudraCT Number: 2007-005882-37 Sponsor Protocol Number: 524 Start Date*: 2008-01-17
    Sponsor Name:BAUSCH&LOMB
    Full Title: RANDOMIZED CONTROLLED CLINICAL STUDY ON THE EFFICACY AND TOLERABILITY OF 0.4% HYALURONIC ACID HYPOTONIC EYE DROPS (IALUREX) VS. HYDROXYPROPYL-GUAR EYE DROPS (SYSTANE) IN THE TREATMENT OF DRY EYE SY...
    Medical condition: Dry eye syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023350 Keratoconjunctivitis sicca LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003391-35 Sponsor Protocol Number: LT1910-PIV-01/06 (NL) Start Date*: 2006-09-13
    Sponsor Name:Laboratoires THEA
    Full Title: Evaluation of the efficacy and safety of unpreserved dexamethasone phosphate 0.1% eye drops (T1910) versus placebo in patients with bilateral treated severe keratoconjunctivitis sicca due to Sjögre...
    Medical condition: keratoconjunctivitis sicca
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023350 Keratoconjunctivitis sicca PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000029-23 Sponsor Protocol Number: NVG06C103 Start Date*: 2008-10-16
    Sponsor Name:Novagali Pharma S.A.
    Full Title: A Phase III, Multicenter, Randomized, Controlled, Double-Masked Trial of NOVA22007 (Ciclosporin 0.1%) Ophthalmic Cationic Emulsion versus Vehicle in Patients with Moderate to Severe Dry Eye Syndrome
    Medical condition: Keratoconjunctivitis sicca (KCS), or dry eye syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023350 Keratoconjunctivitis sicca PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) FR (Completed) ES (Completed) IT (Completed) DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-002804-38 Sponsor Protocol Number: AMASS Start Date*: 2020-08-12
    Sponsor Name:Rigshospitalet-Glostrup
    Full Title: A randomized clinical trial evaluating allogeneic adipose-derived mesenchymal stem cells as a treatment of dry eye disease in Sjögren's Syndrome
    Medical condition: The trial will include participants with Aqueous Deficient Dry Eye Disease due to Sjögrens syndrom (International Classification of Diseases-10: DM 350A)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10023350 Keratoconjunctivitis sicca LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-000160-97 Sponsor Protocol Number: NVG10E117 Start Date*: 2011-04-08
    Sponsor Name:NOVAGALI Pharma S.A.
    Full Title: A MULTICENTER, RANDOMIZED, DOUBLE-MASKED, 2 PARALLEL ARM, VEHICLE CONTROLLED, 6-MONTH PHASE III TRIAL WITH A 6 MONTH OPEN LABEL TREATMENT SAFETY FOLLOW-UP PERIOD TO EVALUATE THE EFFICACY AND SAFETY...
    Medical condition: Severe Dry Eye Disease
    Disease: Version SOC Term Classification Code Term Level
    13.1 10015919 - Eye disorders 10013774 Dry eye PT
    13.1 10015919 - Eye disorders 10013777 Dry eye syndrome LLT
    13.1 10015919 - Eye disorders 10023350 Keratoconjunctivitis sicca PT
    13.1 10015919 - Eye disorders 10013778 Dry eyes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) BE (Completed) DE (Completed) IT (Ongoing) AT (Completed) GB (Completed) CZ (Completed) ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2012-002066-12 Sponsor Protocol Number: NVG12D122 Start Date*: 2012-12-13
    Sponsor Name:NOVAGALI Pharma S.A.S
    Full Title: A Multicenter, Open Label, Interventional, Prospective, Non Randomized, One Cohort Extension Study To Assess the Sustainability of the Effect of NOVA22007 Following Treatment Discontinuation in Imp...
    Medical condition: Severe Dry Eye Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10023350 Keratoconjunctivitis sicca LLT
    14.1 10015919 - Eye disorders 10013778 Dry eyes LLT
    14.1 10015919 - Eye disorders 10013777 Dry eye syndrome LLT
    14.1 10015919 - Eye disorders 10013774 Dry eye PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) AT (Completed) DE (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000991-34 Sponsor Protocol Number: DMP 81.1.05 Start Date*: 2006-04-21
    Sponsor Name:Dr. Gerhard Mann, Chem-pharm. Fabrik GmbH
    Full Title: A randomized, double-blind, monocentric phase IV clinical study on the ocular tolerability of a topical ophthalmic product containing Retinolpalmitat 1000 I.U. in comparison to a reference product ...
    Medical condition: Patients suffering from keratoconjunctivitis sicca (dry eye) and break-up-time (BUT) values < 10 sec
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004929-33 Sponsor Protocol Number: SiccaIkervis Start Date*: 2018-12-05
    Sponsor Name:KH Hietzing, Department of Ophthalmology
    Full Title: Effect of Ciclosporin eyedrops on ocular symptoms and optical image quality in patients with primary or secondary Sjögren syndrome
    Medical condition: primary or secondary Sjögren Syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024254-11 Sponsor Protocol Number: CF101-301KCS Start Date*: 2011-03-30
    Sponsor Name:Can-Fite BioPharma, Ltd
    Full Title: A Phase 3, Randomized, Double-Masked, Placebo-Controlled, Dose-Finding, Parallel-Group Study of the Safety and Efficacy of Daily CF101 Administered Orally in Patients with Moderate-to-Severe Dry Ey...
    Medical condition: Moderate-to-severe Dry Eye disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10013774 Dry eye PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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